Fluoxetine for reducing postoperative cognitive dysfunction in elderly patients after total knee replacement: study protocol for a single-centre, double-blind, randomised, parallel... by Yusheng Yao, Hong Ye, Yushan Wu, Daoyi Lin, Lulu Yu, Jiaxin Chen

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Comparing the effectiveness, safety and tolerability of interventions for depressive symptoms in people with multiple sclerosis: a systematic review and network meta-analysis proto... by Amalia Karahalios, Allan G Kermode, Yvonne C Learmonth, Julia Lyons, Stephanie Campese, Alexandra Metse, Claudia H Marck

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Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled t... by Torben Hansen, Tina Vilsbøll, Filip Krag Knop, Alexander Sidelmann Christensen, Heidi Storgaard, Sofie Hædersdal

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Development of a core patient-reported outcome set for use in HIV care at the individual patient level in Montreal: protocol for a two-phased multimethod project by Bertrand Lebouché, Karine Lacombe, David Lessard, Kim Engler, Romain Palich

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Identification and prevalence of frailty in diabetes mellitus and association with clinical outcomes: a systematic review protocol by David A McAllister, Frances S Mair, Peter Hanlon, Isabella Fauré, Neave Corcoran, Elaine Butterly, Jim Lewsey

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Nomogram model and risk score predicting overall survival and guiding clinical decision in patients with Hodgkin’s lymphoma: an observational study using SEER population-based data... by Yue Yang, Shang Li, Xiao Zhu, Yi Kong, Mingtao Zhang, Xiangping Liang, Zherui Zhang, Shuzhen Tan, Yingqi Li, Yueyuan Zhong, Yingqi Shao, Jiayi Xu, Zesong Li

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Thirty years from FDA approval of pegylated liposomal doxorubicin (Doxil/Caelyx): an updated analysis and future perspective by Alberto A Gabizon, Shira Gabizon-Peretz, Shadan Modaresahmadi, Ninh M La-Beck

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Efficacy, efficiency and safety of a cardiac telerehabilitation programme using wearable sensors in patients with coronary heart disease: the TELEWEAR-CR study protocol by Andrew Xanthopoulos, Eleni Kapreli, Garyfallia Pepera, Konstantinos I Gourgoulianis, Varsamo Antoniou, Gregory Giamouzis, Constantinos Davos, Ladislav Batalik, Vasileios Stavrou, John Skoularigis

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Evaluation of the implementation in primary care of genetic testing for the screening of MODY2 (iMOgene): protocol for an implementation pilot study by Marie-Ève Poitras, Luigi Bouchard, Samuel Legeay, Vanessa Tremblay-Vaillancourt, Amélie Fournier, Josianne Leblanc, Philippe Caron, Catherine Savard, Nathalie Bettez, Karine Tremblay

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Midwives’ knowledge and perspectives on neonatal resuscitation and survival before and after Helping Babies Breathe training: a qualitative study in Uganda by Anna Bergstrom, Josaphat Byamugisha, Susanna Myrnerts Höök, Marielle Abrahamsson, Sarah Namusoko

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Nature and prevalence of long-term conditions in people with intellectual disability: retrospective longitudinal population-based study by Ashley Akbari, Navjot Kaur, Rania Kousovista, Gemma Lewin, Emeka Abakasanga, Rishika Shivamurthy, Georgina Cosma, Gyuchan Jun, Satheesh Gangadharan

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Self-reported sexually transmitted infections and associated factors among sexually active men in East Africa: a multilevel analysis of recent demographic and health surveys by Beminate Lemma Seifu, Yohannes Mekuria Negussie, Bezawit Melak Fente, Zufan Alamrie Asmare, Angwach Abrham Asnake, Meklit Melaku Bezie, Hiwot Atlaye Asebe

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Uncovering the boundary conditions of the association between concerns about falling and physical activity in adult populations: a scoping review protocol by Jason Brian Reed, Steve Amireault, Reese Colby Kerschner, Emilie Ann Chadwell, Heesoo Roh, Emily Ryan Jakob, Kelsie Jo Muller

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Physical activity for children and adolescents with attention deficit hyperactivity disorder: a protocol of a systematic review and meta-analysis by Ole Jakob Storebø, Marie-Louise Jensen, Merete Bender Bjerrum, Marianne Vamosi

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Effects of aerobic exercise on cognitive function and quality of life in patients with Alzheimer’s disease: a systematic review and meta-analysis by Linlin Yang, Zhichao Yuan, Chenggen Peng

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Improving quality and safety in nursing homes and home care: the study protocol of a mixed-methods research design to implement a leadership intervention by Eline Ree, Terese Johannessen, Siri Wiig, Torunn Strømme, Ingunn Aase, Roland Bal, Karina Aase, Marianne Storm, Berit Ullebust, Elisabeth Holen-Rabbersvik, Line Hurup Thomsen, Anne Torhild Sandvik Pedersen, Hester van de Bovenkamp

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Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

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Effect of bortezomib on the treatment of multiple myeloma: a systematic review protocol by Vania dos Santos Nunes-Nogueira, Lucas Oliveira Cantadori, Rafael Dezen Gaiolla

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Association of overweight and obesity with hypertension, diabetes and comorbidity among adults in Bangladesh: evidence from nationwide Demographic and Health Survey 2017–2018 data... by Sukanta Das, Manabika Debnath, Sunanda Das, Snigdha Sarkar, Afrin Sadia Rumana

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Effect of electroacupuncture on symptoms of female pelvic organ prolapse (stage II–III) (EAPOP study): protocol of a randomised controlled trial by Yan Yan, Zhishun Liu, Huan Chen, Xiaoxu Liu, Hangyu Shi

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