Criteria to define rare diseases and orphan drugs: a systematic review protocol by Katie Kerr, Ghada Mohammed Abozaid, Amy McKnight, Hussain A Al-Omar

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Laparoscopic versus open left hemicolectomy for left-sided colon cancer: protocol for a systematic review and meta-analysis by Yang Yang, Yong Wang, Lie Yang, Qiang Du, Jianhao Zhang, Xueting Liu

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Assessing the impact of different donor milk treatments on infant health and growth: a systematic review protocol by Daniel Klotz, Carolyn Smith, Agnieszka Bzikowska-Jura, Marzia Giribaldi, Tanya Cassidy, Laura Cavallarin, Serena Gandino, Karolina Karcz, Chiara Peila, Bartłomiej Walczak, Aleksandra Wesolowska

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Analysis of influencing factors of narrative medicine competence in the clinical nursing population in Hunan province, China: a cross-sectional study by Chao Yang, Siqi Zhang, Hao Yin, Wanying Su, Hailing Qiu, Yingyan Pan, Qiong Qi

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Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study by Arthur Clement, Lee S Nguyen, Anousone Daulasim, Magali Souibri

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Women's perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey by Irene Petersen, Hedvig Nordeng, Angela Lupattelli, Rachel L McCrea

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Mapping spreading depolarisations after traumatic brain injury: a pilot clinical study protocol by Anant Naik, Samuel W Cramer, Isabela Peña Pino, Danielle Carlson, Michael C Park, David P Darrow

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Patterns of prescription opioid use in Swiss emergency department patients and its association with outcome: a retrospective analysis by Aristomenis K Exadaktylos, Gregor Lindner, Georg-Christian Funk, Bertram K Woitok, Petra Büttiker, Svenja Ravioli

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Diagnostic yield of chest and thumb ECG after cryptogenic stroke, Transient ECG Assessment in Stroke Evaluation (TEASE): an observational trial by Peter Magnusson, Adam Lyren, Gustav Mattsson

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Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort st... by Piet Geusens, Jacqueline R Center, Tuan V Nguyen, Thach Tran, Johanna Driessen, Joop P van den Bergh, John Eisman, Caroline E Wyers, Lisanne Vranken, Robert Y Van der Velde, Heinrich M J Janzing, Sjoerd Kaarsemakers, Dana Bliuc

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Work-related musculoskeletal disorders, fatigue and stress among gas station workers in China: a cross-sectional study by Jing Wang, Andrew Paul Smith, Jialin Fan, Xiaotong Tan

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Physical activity behaviour up to 1 year post-rehabilitation among adults with physical disabilities and/or chronic diseases: results of the prospective cohort study ReSpAct by Lucas H V van der Woude, Rienk Dekker, Trynke Hoekstra, Leonie A Krops, Femke Hoekstra, Florentina J Hettinga, Pim Brandenbarg, Bregje L Seves

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Deployment and uptake of COVID-19 vaccines for refugees and migrants in regular and irregular situations: a mixed-method multicountry study by Biraj Man Karmacharya, Karl Blanchet, Jai K Das, Laetitia Nyirazinyoye, Maria Midea M Kabamalan, Nguyen Toan Tran, Zahra A Padhani, Anjali Joshi, Seyed-Moeen Hosseinalipour, Enrique Teran, Pierina Benavente, Vinay N Kampalath, Moussa Lonkila Zan, Elżbieta Anna Czapka, Cheryl Martens, Vicente B Jurlano

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Potential traumatic events in the workplace and depression, anxiety and post-traumatic stress: a cross-sectional study among Dutch gynaecologists, paediatricians and orthopaedic su... by Maria G van Pampus, Karel Willem Frank Scheepstra, Hannah S Pauw, Minouk Esmee van Steijn, Claire A I Stramrood, Miranda Olff

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Non-utilisation of postpartum services in northwestern Nigeria: analyses of trend and social determinants from 2003 to 2018 by Dyah Anantalia Widyastari, Abubakar Abbani Yakubu, Yothin Sawangdee, Pojjana Hunchangsith

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Public satisfaction with Healthy China Action Plan implementation: a web-based cross-sectional survey in southwest China by Li Pan, Yi Chen, Virasakdi Chongsuvivatwong, Dongyang Liu, Wuzhao Chen, Xinyu Bai

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Health Canada's use of its priority review process for new drugs: a cohort study by Joel Lexchin

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Association of preoperative blood biomarkers with postoperative major adverse cardiac events and mortality in major orthopaedic surgery: a systematic review and meta-analysis by Lin Lu, Yi Ren, Zhen Hua, Yanxia Sun, Zhenghao Wen, Suzhen Zhou

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Randomised controlled trial to investigate the effectiveness of local oestrogen treatment in postmenopausal women undergoing pelvic organ prolapse surgery (LOTUS): a pilot study to... by Jane Daniels, Lee Middleton, Tina Sara Verghese, Versha Cheed, Lisa Leighton, Pallavi Manish Latthe

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Influencing basic behavioral mechanisms of action while targeting daily walking in sedentary adults at risk for cardiovascular disease: randomised factorial design protocol by Karina W Davidson, Ying Kuen Cheung, Joan Duer-Hefele, Jerry Suls, Ashley M Goodwin, Samantha Gordon, Ravneet Sahni, Frank Vicari, Kaitlyn Accardi, Salvatore Crusco, Ciaran Friel, Elizabeth A Vrany

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