Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies by Jinlin Hou, Thomas Berg, Arndt Vogel, Teerha Piratvisuth, Jörg Trojan, Enrico N. De Toni, Masatoshi Kudo, Katarina Malinowsky, Peter Findeisen, Johannes Kolja Hegel, Wenzel Schöning, Kairat Madin, Konstantin Kroeniger, Henry Lik-Yuen Chan, Ashish Sharma

“…Background & Aims: We compared the clinical performance of the novel GAAD (gender [biological sex], age, alpha-fetoprotein [AFP], des-gamma carboxyprothrombin [DCP]) and GALAD (gender [biological sex], age, AFP, Lens culinaris agglutinin-reactive AFP [AFP-L3], DCP) algorithms to deduce the clinical utility of AFP-L3 for detecting early-stage hepatocellular carcinoma (HCC) from chronic liver disease (CLD). …”
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Stenotrophomonas maltophilia bacteremia in adult patients with hematological diseases: clinical characteristics and risk factors for 28-day mortality by Wenjing Guo, Qingsong Lin, Jia Li, Xiaomeng Feng, Sisi Zhen, Yingchang Mi, Yizhou Zheng, Fengkui Zhang, Zhijian Xiao, Erlie Jiang, Mingzhe Han, Jianxiang Wang, Sizhou Feng

“…Patients with high SOFA scores, advanced age, pulmonary infection, or recent tigecycline exposure are at higher risk of mortality. …”
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scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria by Collins M. Morang’a, Riley S. Drake, Riley S. Drake, Riley S. Drake, Riley S. Drake, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Nancy K. Nyakoe, Dominic S. Y. Amuzu, Vincent Appiah, Yaw Aniweh, Yaw Bediako, Saikou Y. Bah, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Gordon A. Awandare, Thomas D. Otto, Lucas Amenga-Etego

“…First, we determined the relationship between host age and parasite density in patients (n = 134/224) compared to controls (n = 90/224). …”
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Prevalence of abnormal bone mineral density and its influencing factors among adult residents in Jiangsu province: a cross-sectional survey by Weihao WANG, Huijing HE, Yaoda HU, Xingming CHEN, Tan XU, Ji TU, Ang LI, Binbin LIN, Qihang LIU, Zhiming LU, Tianshu XI, Haibo HUANG, Da XU, Zhili CHEN, Zichao WANG, Guangliang SHAN

“…Age ≥ 60 years, hypertension, and menopause were risk factors for abnormal BMD in female adults, whereas high school education and moderate physical work were protective factors. …”
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Editorial by Jörg Tremmel, Maria Lenk, Antony Mason, Markus Rutsche

“…Since some cohorts are born into favourable eras, and others are not, it is important to examine  intergenerational public finances by reference to the standard of living inherited by different age groups, and the socio-economic circumstances they currently face. …”
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Adverse events in the nervous system associated with blinatumomab: a real-world study by Wen Gao, Jingwei Yu, Yifei Sun, Zheng Song, Xia Liu, Xue Han, Lanfan Li, Lihua Qiu, Shiyong Zhou, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

“…Concomitant use of medication for age, musculoskeletal system, genitourinary system, and sexual hormones were independent risk factors for NST, and age was an independent protective factor for fatal NST. …”
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Models based on dietary nutrients predicting all-cause and cardiovascular mortality in people with diabetes by Fang Wang, Yukang Mao, Jinyu Sun, Jiaming Yang, Li Xiao, Qingxia Huang, Chenchen Wei, Zhongshan Gou, Kerui Zhang

“…The association of key dietary nutrients with all-cause and cardiovascular mortality were visualized by restricted cubic spline (RCS) models both in the whole and subgroups by sex, age, drinking and smoking status. The overall median age of the cohort was 62.0 years (interquartile range (IQR) 52.0–70.0), 2564 (50.67%) being male. …”
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Comparison of ultrasonographic features between two types of hepatic echinococcosis and hepatoblastoma in children by Yi Tao, Hanqing Kong, Jiawu Li, Zhizhi Tan, Jun Wang, Yan Luo

“…The mean age of 36 children with hepatoblastoma was 2.9 ± 3.0 years. …”
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Medication adherence and blood pressure control in treated hypertensive patients: first follow-up findings from the PREDIcT-HTN study in Northern Bangladesh by Ahmed Hossain, Gias Uddin Ahsan, Mohammad Zakir Hossain, Mohammad Anwar Hossain, Probal Sutradhar, Sarowar-E. Alam, Zeeba Zahra Sultana, Heba Hijazi, Syed Azizur Rahman, Mohamad Alameddine

“…Results Analysis of 2276 hypertensive patients (mean age 51.31 ± 11.58 years) revealed that 36.1% had grade-I and 24.2% had grade-II uncontrolled hypertension. …”
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First-trimester Doppler Ultrasound for Predicting Successful Management of Pregnancy with Recurrent Pregnancy Losses Due to Antiphospholipid Syndrome and Thrombophilia: A Cohort St... by Muhammad Adrianes Bachnas, Uki Retno Budihastuti, Eriana Melinawati, Nutria Widya Purna Anggraini, Robert Ridwan, Lini Astetri, Agung Sari Wijayanti, Atthahira Amalia Hafiizha, Muhammad Denny Gagah Pradana, Aliffudin Nur, Muhammad Alamsyah Azis, Wiryawan Permadi, Luthfi Rahman, Jimmy Yanuar Annas, Daniel Jonathan Mangapul Siagian, Neissya Nastiti Firmanto, Gilang Rizqy Perdana Aries Rohman, Muhammad Ilham Aldika Akbar

“…Maternal characteristics – including age, BMI, number of pregnancy losses, etiopathology and immuno-inflammatory response – were considered in the analysis. …”
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Unconventional use of injectable long-acting cabotegravir and rilpivirine against HIV-1 in PWH in clinical need: 52 weeks real-world data by Valentina Iannone, Roberto Rossotti, Nicholas Brian Bana, Gabriele Cavazza, Federico D’Amico, Francesca Lombardi, Pierluigi Francesco Salvo, Gianmaria Baldin, Simona Di Giambenedetto, Dario Bernacchia, Gabriele Pagani, Alberto Borghetti, Stefano Rusconi

“…Overall probability of discontinuation was 14.9% at week 52. Younger age was protective against discontinuation (HR 0.93, 95%CI 0.88–0.99, p = 0.048). …”
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Medical care and initial health status of French children returnees from jihadist group operation areas: A cross-sectional study from 2017 to 2020 in one referral French hospital by J. Goutines, L.L. Pham, N. Lucidarme, C. Briand, A. Malka, C. Baker, M. Veyret-Morau, A. Mapelli, A. Klein, T. Baubet, L. De Pontual

“…Findings: We included 70 children (44M, 26F; mean age: 4.9 years old (±3.8)). In average, they crossed two countries, mainly Syria (n = 55), Turkey (n = 53) and Iraq (n = 18). …”
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Exploring Chronic Pain in Hemodialysis Patients: An Observational Study Based on the New IASP Classification for ICD-11 by Vittorio Schweiger, Martina Cacciapuoti, Marta Nizzero, Salvatore Simari, Gianmarco Lombardi, Leonardo Gottin, Lisa Stefani, Alvise Martini, Giustino Varrassi, Gabriele Finco, Enrico Polati, Giovanni Gambaro

“…Risk factors for chronic pain in HD patients are older age, long-lasting dialysis history, several concomitant diseases, malnutrition, and others. …”
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Incidence of shoulder dislocations in the UK, 1995–2015: a population-based cohort study by Gary S Collins, Sarah E Lamb, Sally Hopewell, Daniel Prieto-Alhambra, Andrew Judge, Amar Rangan, Andrew J Carr, Jonathan L Rees, Nigel K Arden, Katherine Edwards, Tim A Holt, Anjali Shah, Antonella Delmestri, Rafael A Pinedo-Villanueva

“…Objective This cohort study evaluates the unknown age-specific and gender-specific incidence of primary shoulder dislocations in the UK.Setting UK primary care data from the Clinical Practice Research Datalink (CPRD) were used to identify patients aged 16–70 years with a shoulder dislocation during 1995–2015. …”
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Clinical benefits of modifying the evening light environment in an acute psychiatric unit: A single-centre, two-arm, parallel-group, pragmatic effectiveness randomised controlled t... by Håvard Kallestad, Knut Langsrud, Melanie Rae Simpson, Cecilie Lund Vestergaard, Daniel Vethe, Kaia Kjørstad, Patrick Faaland, Stian Lydersen, Gunnar Morken, Ingvild Ulsaker-Janke, Simen Berg Saksvik, Jan Scott

“…The Intent to Treat sample comprised 476 individuals (mean age 37 (standard deviation (SD) 13.3); 193 (41%) were male, 283 (59%) were female). …”
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Prevalence of AZFс Y chromosome microdeletions and association with spermatogenesis in Russian men from the general population by L. V. Osadchuk, G. V. Vasiliev, M. K. Ivanov, M. A. Prasolova, M. A. Kleshchev, A. V. Osadchuk

“…Age, weight, height, and the volume, concentration, total count, proportion of motile and morphologically normal spermatozoa in the ejaculate were recorded for all participants. …”
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Esophageal lesions at irritable bowel syndrome by M. G. Mnatsakanyan, O. V. Tashchyan, Yu. A. Morozova, A. P. Pogromov, G. M. Dyukova, D. V. Khalyapina

“…Of them 52 were men, 149 — women, mean age was 41,8±9,5 years. In 70 (35%) of them (21men, 49 women, mean age — 42,3±12,0 years) heartburn, belching, epigastric dyscomfort, non-coronary retrosternal pain were present along with IBS. …”
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Anatomical and Functional Outcomes of Vitrectomy with/without Intravitreal Methotrexate Infusion for Management of Proliferative Vitreoretinopathy Secondary to Rhegmatogenous Retin... by Samir El Baha, Mahmoud Leila, Ahmed Amr, Mohamed M. A. Lolah

“…Study Groups I, II, and III included 42, 35, and 24 eyes, respectively. Mean age was 45 years. Male gender constituted 70% of patients. …”
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Population Dynamics of Bullet Tuna (Auxis rochei Risso 1881) from the Indian Ocean, West Nusa Tenggara, Indonesia by Evron Asrial, Ruly Isfatul Khasanah, Fathurriadi Fathrurriadi, Yasir Arapat, Usma Kurniawan Hadi, Lalu Achmad Tan Tilar Wangsajati Sukmaring Kalih, Lalu Samsul Rizal, Mita Ayu Liliyanti, Erwin Rosadi, Daduk Setyohadi, Muhammad Junaidi, Ishani Nelunika Rathnayake

“…The length-weight relationship curve showed that BLT was in an immature age group (adolescent fish). Meanwhile, the composition of BLT is worth selling (Condition Factor > 1.00), fit for catch (FLc / FLm > 1.00) and worthy of maturity (FLc > FLm), respectively 99.92%, 0.82% and 0.00%. …”
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Incidence, prevalence, and predictors of osteoporotic fracture in adult lung transplant recipients by Elisabeth Ng, Shanal Kumar, Eldho Paul, Daniel Bennett, Luisa Rosi, Louise Fuller, Lauren Chiu, Shoshana Sztal-Mazer, Steven Ivulich, Greg Snell, Leon A. Bach, Kathryn L. Hackman

“…Results: Four hundred and five LT recipients (41% female, median age 59 years) had a median follow-up of 4.9 years (interquartile range 3.4-6.7). …”
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