Effect of Acupuncture at ST36 on Signal Transduction Pathways of BDNF-CREB in Dentate Gyrus of Telomerase Knockout Mice by Xiaoting YANG, Shiyi QI, Shen LIN, Dong LIN

“…Objective:To explore the effect of acupuncture on BDNF-CREB related signaling pathway in hippocampal dentate gyrus of Telomerase knockout mice (Terc-/-mice) and its neuro protective mechanism, in order to promote hippocampal neurogenesis, delay aging, improve learn cognitive skills, and provide possible pathways and experimental evidence.Methods:The phenotype was identified by polymerase chain reaction, and eighteen telomerase knockout mice with a length of 350 bp were selected, weighing (20±5) g. …”
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Influence of symptoms of attention deficit hyperactivity disorder on emotional behavioral problems： parallel mediating effect of different dimensions of executive function by XUE Yiyun, OU Zixin, HONG Danping, DANG Caiping, ZHU Zhihang, CHENG Daomeng, HU Yingzi, LI Guoquan, YANG Chanjuan, YIN Weizhen

“…Methods A total of 102 children with ADHD aged 6-12 years old who met the Diagnostic and Statistical Manual of Mental Disorders 5th edition （DSM-5） criteria were selected as the study subjects. …”
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Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…In this study were included 86 patients aged from 18 to 65 years with moderate or severe active inflammatory bowel disease (61 — UC, 25 — CD). …”
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Utilities Associated with the Treatment of Growth Hormone Deficiency (GHD): A Time Trade-off (TTO) Study in the UK and Canada by Kirsch S, Butler G, Jensen LDF, Okkels A, Yssing C, Håkan-Bloch J

“…Based on a pilot, data collection was conducted in two surveys only (Survey A and Survey B). In Survey A, adults aged ≥ 18 years evaluated health states as if they were receiving injections themselves. …”
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Exploring parenthood intentions and perceptions of infertility and assisted reproductive technology among 2SLGBTQIA + young adults in Ontario, Canada: a mixed methods study by Caitlin I. T. Ennis, Nurasha G. Fernando, Karen P. Phillips

“…Methods An online survey, designed as mixed-methods with sex-and-gender-based analysis (SGBA +), was used to recruit childless, post-secondary students, aged 18–30 years, in May–October 2022. Survey questions were analyzed by descriptive statistics across gender groups. …”
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Evaluation of a Global Initiative for Asthma Education and Implementation Program to Improve Asthma Care Quality (CARE4ALL): Protocol for a Multicenter, Single-Arm Study by Kewu Huang, Wenjun Wang, Ying Wang, Yanming Li, Xiaokai Feng, Huahao Shen, Chen Wang

“…Approximately 1500 patients with asthma aged ≥14 years will be enrolled in participating hospitals and followed up for 48 weeks. …”
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The relationship between negative psychological state and quality of life among cardiovascular disease patients in China: the masking effect of abnormal dietary behavior by QingNing Chang, QingNing Chang, HaiBo Ma, Can Zhang, Xin Li, YiBo Wu, LiNa Ha

“…The purpose of this study was to construct a moderated mediation model to explore the roles of abnormal dietary behavior and family health in the mechanism through which depression/anxiety influences Quality of life (QoL) in patients with cardiovascular disease.MethodsA field survey was conducted in China and ultimately included 730 patients with cardiovascular disease aged 20–60 years. Data were collected using the Europe Quality of five-dimensional five-level questionnaire, Short-Form of the Eating Behavior Scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and the Chinese version of the short-form of the Family Health Scale. …”
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Determination of the Contents of Antioxidants and Their Degradation Products in Sodium Chloride Injection for Blood Transfusion by Bo Tao, Gang Wang, Zongning Yin, Xiaocong Pu, Yan Jiang, Luohong Zhang, Jie Cheng, Yong Li, Jiayu Zhang

“…Antioxidants are usually added to these polymer materials in the production process to prevent the materials from aging and enhance the stability of the materials. …”
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The influence of locus of control, coping strategies and time perspective on post-traumatic growth in survivors with primary breast cancer by Alexandra-Cristina Paunescu, Marina Kvaskoff, Cyrille Delpierre, Lidia Delrieu, Guillemette Jacob, Myriam Pannard, Marie Préau

“…Results The study included 821 BCSs aged 26 to 79 years, one to 16 years after cancer diagnosis. …”
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Symptom patterns in patients newly sick listed for common mental disorders and associations with work-related and socioeconomic factors: a cross-sectional study in Swedish primary... by Cecilia Björkelund, Dominique Hange, Eva-Lisa Petersson, Irene Svenningsson, Nashmil Ariai, Lilian Wiegner

“…Objective The aim was to determine symptom patterns of depression, anxiety and stress-related mental disorders in newly sick listed due to common mental disorders in Swedish primary care patients and to examine associations with sick leave diagnosis, also in relation to socioeconomic, work-related and demographic factors.Design Cross-sectional study.Setting Primary care in western Sweden.Participants From a randomised controlled trial, patients aged 18–67, seeking primary care and on sick leave due to depression, anxiety and/or mental stress, in total 341 individuals, during 2018–2020.Primary outcome measures Patterns of depressive, anxiety and stress symptoms measured via self-assessment questionnaires (Montgomery Asberg Depression Rating Scale-Self (MADRS-S), General Anxiety Disorder Scale-7 (GAD-7), Karolinska Exhaustion Disorder Scale (KEDS)), sick leave diagnosis, perception of Work Ability Index and job strain via the job strain model.Results A combination of high levels of depressive and stress-related symptoms was more frequent than single symptom clusters among persons with common mental disorders (CMD) on sick leave: 7% of the patients had scores above cut-off for one of the instruments MADRS-S, GAD-7 and KEDS, 12% above cut-off for two and 80% had above cut-off for all three instruments. …”
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Efficacy of solution-focused brief therapy versus case management for psychological distress in adolescents and young adults in a community-based youth mental health service in Sin... by Janhavi Ajit Vaingankar, Edimansyah Abdin, Charmaine Tang, Cheryl Yunn Shee Foo, Tianyi Hui, Nur Khairunisa Binte Ngaiman, Darshan s/o Dahjalarrajah, Yi Chian Chua, Yi Ping Lee

“…From September 2023 to March 2025, the study will recruit 124 participants (aged 16–30) presenting at a national youth mental health service in Singapore (CHAT, Centre of Excellence for Youth Mental Health) with clinically assessed general psychological distress, subthreshold or prodromal symptoms, or a first episode of a mood disorder. …”
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The obesity paradox in osteoporosis risk among older adults is mostly driven by women: a population-based prospective study by Qingfeng Luo, Shiyong Zhang, Zixin Liang, Danni Wang, Yanlin Zhong, Bin Xia, Peng Xie, Can Wang, Jinqiu Yuan, Ziji Zhang, Xingsheng Li

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Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…The study included 86 patients with moderate to severe active disease (61 with UC and 25 with CD) aged 18 to 65 years. To induce remission, all patients had the first course of prednisone at a starting dose of 30 to 60 mg/day, with a subsequent reduction. …”
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Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators by S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema, Craig N. Jenne

“…Plasma mediator levels, analyzed by Luminex multiplex assays, were evaluated in children aged 5-17 years with nonappendicitis abdominal pain (NAAP), acute appendicitis (AA), and nonappendicitis sepsis (NAS). …”
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Domestic violence victimisation and its association with mental distress: a cross-sectional study of the Yangon Region, Myanmar by Johanne Sundby, Espen Bjertness, Lars Lien, Win Thuzar Aye, Hein Stigum, Berit Schei

“…Prevalence estimates and associations were presented with a 95% CI and the Wald test.Setting Urban and rural areas of the Yangon region, Myanmar.Participants Men and women ages 18 to 49 years were included. Institutionalised people, monks, nuns and individuals deemed too ill physically and/or mentally to participate were excluded.Results A random sample of 2383 people was included in the analyses. …”
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How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects by Pradipta IS, Aprilio K, Ningsih YF, Pratama MAA, Gatera VA, Alfian SD, Iskandarsyah A, Abdulah R

“…Treatment nonadherence was associated with socioeconomic-related factors of being aged 15– 65 years, living in rural areas, having history of formal education, and having a household size of 2– 6 people. …”
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Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials by Igho J Onakpoya, Elizabeth T Thomas, Joseph J Lee, Ben Goldacre, Carl J Heneghan

“…Objective To assess the benefits and harms of pregabalin in the management of neuropathic pain.Design Rapid review and meta-analysis of phase III, randomised, placebo-controlled trials.Participants Adults aged 18 years and above with neuropathic pain defined according to the International Association for the Study of Pain criteria.Interventions Pregabalin or placebo.Primary and secondary outcome measures Our primary outcomes were pain (as measured using validated scales) and adverse events. …”
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Assessing the use of geospatial data for immunization program implementation and associated effects on coverage and equity in the Democratic Republic of Congo by Dosithée Ngo-Bebe, Patricia Mechael, Fulbert Nappa Kwilu, Théophane Kekemb Bukele, Félicité Langwana, Genèse Lolimo Lobukulu, Marcelo Ilunga Kalonji, Bahindwa Kalalizi, Kevin Tschirhart, Christophe Lungayo Luhata, Carine Gachen

“…A secondary analysis of immunization coverage survey data (2020–2022) was conducted to assess the associated effects on immunization coverage, especially changes in rates of zero dose children, defined as those aged 12–23 months who have not received a single dose of Pentavalent vaccine. …”
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Impact of Prone Position on 12-Lead Electrocardiogram in Healthy Adults: A Comparison Study with Standard Electrocardiogram by Yunis Daralammouri, Murad Azamtta, Hamza Hamayel, Amro Adas, Osama Sawalmeh, Yahia Ismail, Saed H. Zyoud

“…A cross-sectional observational study enrolled forty healthy adults (24 males and 16 females) aged between 18 and 40 years. The ECG was performed in two different body positions, supine and prone. …”
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A study on the variability and correlation of ocular biological measurement parameters in adult myopic patients by Fangxing Zhou, Nan Chen, Hui Qian, Di Gong, Kunke Li

“…ObjectiveThis study aims to explore the differences in ocular parameters among adult myopic patients with different degrees of myopia and axial lengths, and to investigate the correlations between these ocular parameters.MethodsThis single-center observational study collected clinical data from myopic patients aged 18–45 years who visited the Eye Hospital of Nanjing Medical University between January and June 2023. …”
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