Levosimendan and Global Longitudinal Strain Assessment in Sepsis (GLASSES 1): a study protocol for an observational study by Iacopo Cappellini, Alessandra Melai, Lucia Zamidei, Maddalena Parise, Simone Cipani, Guglielmo Consales

“…The use of levosimendan in cardiogenic shock during sepsis is still under debate.Methods We are conducting an observational, single-centre, not-for-profit study enrolling patients aged 18–80 years old admitted to the intensive care unit with a diagnosis of septic shock. …”
Get full text

Performance of HPV E4 and p16INK4a biomarkers in predicting regression of cervical intraepithelial neoplasia grade 2 (CIN2): protocol for a historical cohort study by David Jenkins, Mark H Stoler, Anne Hammer, Torben Steiniche, Lone Kjeld Petersen, Patti E Gravitt, Rikke Kamp Damgaard, Maurits NC de Koning, Wim GV Quint, John Doorbar, Johnny Kahlert

“…However, data on HPV E4/p16INK4a as a predictor for CIN2 regression is lacking.Methods and analysis We will conduct a historical cohort study including 500 women aged 23–40 years with a first CIN2 diagnosis in Aarhus, Denmark during 2000–2010. …”
Get full text

Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial by Thanh Huu Khieu, Dung Phuong Le, Binh Thanh Nguyen, Binh Thanh Ngo, Hong Thi Chu, Duc Minh Truong, Hung Minh Nguyen, Anh Hoa Nguyen, Tung Dinh Pham, Anh Thi Van Nguyen

“…Eighty-two patients (41 per group), aged 1 month to 12 years, received standard care along with nasal spraying of either physiological saline (Control group) or LiveSpo Navax (Navax group), administered three times daily over a 7-day follow-up period. …”
Get full text

Correlation Between the Inferior Vena Cava/Aorta (Ivc/Ao) Ratio and Serum Lactate Levels in Children With Renal Disorder by Hakim DDL, Widiasta A, Rachmadi D, Rahayunigsih SE, Apandi PR, Adrizain R, Martiano MRA

“…Understanding these parameters could improve early diagnosis, aid clinical decisions, and enhance outcomes for pediatric AKI patients, offering an accessible monitoring method for clinicians.Methods: This cross-sectional study involved 48 pediatric patients aged 5– 18 years showing Pediatric Early Warning Score (PEWS) ≥ 3 and diagnosed with renal disorders. …”
Get full text

Some haematological values in the healthy kangol dogs and german wolfdogs by Zafer Durgun, Mursayettin Eksen, Ercan Keskin

“…In this study, 11 male, 7 temale Kangal do gs and 18 male, 10 temale German Wolfdogs, aged, 1-3 were used. The required blood for haematological analysis were taken from v. cephalica antebrachi or v. saphena parva.…”
Get full text

Malaria and Geohelminthiasis Coinfections in Expectant Women: Effect on Maternal Health and Birth Outcomes in a Malaria Endemic Region in Kenya by Wekesa Antony Wanyonyi, Chrispinus Siteti Mulambalah, David H. Mulama, Elizabeth Omukunda, Darwin Injete Siteti

“…To collect data on malaria and maternal haematological parameters, blood samples were obtained from 750 participants aged 18-49 years and analyzed. Haemoglobin and eosinophils levels were determined by coulter counter while malaria parasitemia levels and red blood cell morphology were assessed by preparing and observing blood smears under the microscope. …”
Get full text

Assessing hemorrhagic risks in combination therapy: implications of angiogenesis inhibitors and immune checkpoint inhibitors by Yuhui Yang, Yuhui Yang, Yuhui Yang, Pingping Long, Pingping Long, Ying Tuo, Ying Tuo, Xiaoxiao Wang

“…Hemorrhagic events were common in females (50.97%) and older patients (aged 64+), frequently occurring within the first 30 days of treatment (38.11%). …”
Get full text

Major Adverse Kidney Events in Hospitalized Older Patients With Acute Kidney Injury: Machine Learning–Based Model Development and Validation Study by Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng, Hong-Shen Wang, Yi-Xin Kang, Shao-Bin Duan

“…MethodsA total of 4266 older patients (aged ≥ 65 years) with AKI admitted to the Second Xiangya Hospital of Central South University from January 1, 2015, to December 31, 2020, were included and randomly divided into a training set and an internal test set in a ratio of 7:3. …”
Get full text

Can Underlying Co-Morbidities Affect Cerebral Oximetry in Cardiac Surgery Patients? by Kianoush Saberi, Shahnaz Sharifi, Amirhossein Orandi

“…This study investigated rSO2 levels, as measured by a cerebral oximeter, in patients aged 19 to 79 undergoing cardiac surgery. Data were collected from both the right and left sides of the forehead during the operative period. …”
Get full text

Lymphoadenopathies caused by Bartonella henselae by V.S. Zhukovskiy, O.V. Prokopiv, I.R. Trutyak, M.V. Pankiv

“…The description of two clinical cases of cat scratch disease in adult women aged 19 and 59 is given. The typical course of the disease in one of them at the beginning of the disease, was manifested by symptoms of general intoxication, fever, an increase of lymph nodes in the neck and axillary area, which coincided in time with the previously diagnosed bacterial angina. …”
Get full text

Intersigmoid Hernia: A Forgotten Diagnosis—A Systematic Review of the Literature over Anatomical, Diagnostic, Surgical, and Medicolegal Aspects by Stella Chiarini, Paolo Ruscelli, Roberto Cirocchi, Vito D’Andrea, Beatrice Sensi, Alberto Santoro, Alessia Corsi, Federico Zepponi, Piergiorgio Fedeli, Sara Gioia

Get full text

Investigating the link between frailty and outcomes in geriatric patients with isolated rib fractures by Yang Cao, Shahin Mohseni, Babak Sarani, Frank Hildebrand, Ahmad Mohammad Ismail, Maximilian Peter Forssten, Marcelo AF Ribeiro

“…In the current investigation, we sought to delineate the association between frailty, measured using the Orthopedic Frailty Score (OFS), and outcomes in geriatric patients with isolated rib fractures.Methods All geriatric (aged 65 years or older) patients registered in the 2013–2019 Trauma Quality Improvement database with a conservatively managed isolated rib fracture were considered for inclusion. …”
Get full text

The Impact of Multidisciplinary Discussion (MDD) in the Diagnosis and Management of Fibrotic Interstitial Lung Diseases by Ghofran Ageely, Carolina Souza, Kaissa De Boer, Saly Zahra, Marcio Gomes, Nha Voduc

Get full text

Genetic parameters and parental and early-life effects of boar semen traits by Pedro Sá, Rodrigo M. Godinho, Marta Gòdia, Claudia A. Sevillano, Barbara Harlizius, Ole Madsen, Henk Bovenhuis

“…Early-life effects included the dam’s parity, ages of the dam and sire, gestation length, litter size, litter sex ratio, number of piglets born alive, number of litter mates at weaning, rearing length, and weight gain. …”
Get full text

Severe Hepatotoxicity in Mushroom Poisoning by Lepiota brunneoincarnata from Complete Recovery to Liver Transplantation: A Case Series with Review on Liver Function Tests and Liver... by Mohammad Hossein Anbardar, Neda Soleimani, Kourosh Kazemi, Zahra Jafarpour, Mahsa Hasani, Sahand Mohammadzadeh, Parnia Torfehnezhad, Sedighe Jafarian, Mahsa Farhadi, Mina Salari Sardari

“…The patients were between the ages of 18 and 67 years, composed of ten females and eight males. …”
Get full text

Assessing the use of the Index of Consciousness (IoC) as a monitoring tool for the sedative effects of ciprofol during general anesthesia induction: a prospective observational stu... by Yanhong Yu, Hao Wang, Liguo Wei, Yifan Gao, Nuo Yan, Jing Chu, Hong Li

“…A total of 130 patients aged 18 to 65 years who underwent noncardiac or noncranial elective surgery under general anesthesia were included. …”
Get full text

OCT-A monitoring of the efficacy of neuroprotective therapy for glaucomatous optic neuropathy by N.G. Glazko, A.E. Egorov

“…</i> </p> <p> <i><b>Patients and Methods: </b>45 patients (78 eyes) aged 45–80 years with moderate and advanced POAG lasting at least one year were enrolled in the study. …”
Get full text

Comparative analysis of long-term outcomes of primary posterior continuous curvilinear capsulorhexis in pseudoexfoliation syndrome by E.V. Egorova, V.V. Chernykh

“…</i> </p> <p> <i><b>Patients and Methods: </b>173 patients (213 eyes) aged 50–84 years with PEX were enrolled in the study. …”
Get full text

Feasibility and Safety of Field-Based Physical Fitness Tests: A Systematic Review by Carolina Cruz-León, Pablo Expósito-Carrillo, Sandra Sánchez-Parente, José Jiménez-Iglesias, Milkana Borges-Cosic, Magdalena Cuenca-Garcia, José Castro-Piñero

“…Objectives (i) To examine the feasibility and safety of existing field-based physical fitness tests used in people of all ages and (ii) to establish a comprehensive view of criterion-related validity, reliability, feasibility and safety based on scientific evidence for the existing field-based physical fitness tests in adults. …”
Get full text

Impact of a Virtual Care Navigation Service on Member-Reported Outcomes Among Lesbian, Gay, Bisexual, Transgender, and Queer Populations: Case Study by Seul Ki Choi, Jaclyn Marshall, Patrina Sexton Topper, Andrew Pregnall, José Bauermeister

“…MethodsThis case study is based on the experience of commercially insured members, aged 18 or older, who used the LGBTQ+ Health Care Navigation (LGBTQ+ Navigation) service by Included Health between January 26 and July 31, 2023. …”
Get full text