Prevalence and Risk Factors of Childhood Hypertension in Urban-Rural Areas of China: A Cross-Sectional Study by Xiaohua Liang, Lun Xiao, Yetao Luo, Jiapei Xu

“…Using stratified cluster sampling in urban and rural areas, a total of 13597 primary school children aged 6∼12 years living in the Southwest of China were included. …”
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A socioecological taxonomy of determinants to colorectal cancer screening in black men: Insights from a mixed-methods systematic review by P.J. Zaire, E. Miller, A.P. Ewing, J. Hefner, K. Wright, L.H. Smith

“…Significant facilitators included aging, receiving a provider recommendation, having social support, and effective culturally appropriate outreach strategies. …”
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Hydroxocobalamin for the treatment of vasoplegia after lung transplantation: A case series by Anh Nguyen, MD, PhD, Rima Bouajram, PharmD, Marek Brzezinski, MD, Sahand Hassanipour, David Gordon, Binh Trinh, MD, Tobias Deuse, MD, Aida Venado, MD, Steve Hays, MD, Jonathan Singer, MD, Jasleen Kukreja, MD, MPH

“…Results: We identified 3 male patients aged 49 to 62, with lung allocation scores between 89.9 and 90.6, requiring extracorporeal membrane oxygenation support (pre- and post-transplant for 5, 5, 9 and 8, 2, 2 days, respectively). …”
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Responsiveness and clinical utility of PROMIS instruments in pediatric Crohn's disease: insights from a longitudinal study by Sara Azevedo, Sara Azevedo, Maria Miguel Oliveira, Maria Miguel Oliveira, Paulo Nogueira, Paulo Nogueira, Paulo Nogueira, Ana Isabel Lopes, Ana Isabel Lopes

“…Integrating patient-reported outcomes (PROs) into clinical practice is crucial for comprehensive disease management.ObjectiveTo evaluate the responsiveness and clinical utility of Patient-Reported Outcomes Measurement Information System (PROMIS) instruments, compared with standard clinical assessment tools in pediatric CD patients.MethodsA longitudinal, prospective study with 31 pediatric Crohn's disease (CD) patients aged 8–17 years recruited from a Pediatric Gastroenterology Unit. …”
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Effect of improving food security on parenting practices and caregiver–adolescent relationships: qualitative findings of an income-generating agricultural intervention in rural Ken... by Maricianah A. Onono, Lila Sheira, Edward A. Frongilio, Gladys Odhiambo, Pauline Wekesa, Amy Conroy, Elizabeth A. Bukusi, Craig R. Cohen, Sheri D. Weiser

“…Aims The study aimed to understand the perceived effects of food security on parenting practices and how this was experienced by both adolescent girls (aged 13–19 years) and their caregivers in rural Kenya. …”
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Results from the PROmoting Early Childhood Outside cluster randomized trial evaluating an outdoor play intervention in early childhood education centres by Rachel Ramsden, Dawn Mount, Yingyi Lin, Emily Fox, Susan Herrington, Janet Loebach, Adina Cox, Anita Bundy, Amber Fyfe-Johnson, Ellen Beate Hansen Sandseter, Michelle Stone, Mark S. Tremblay, Mariana Brussoni

“…This study included eight ECECs delivering licensed care to children (n = 217) aged 2.5 to 6 years in Greater Vancouver, British Columbia, Canada. …”
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Acute Severe Anaphylaxis in Nepali Patients with Neurotoxic Snakebite Envenoming Treated with the VINS Polyvalent Antivenom by Sanjib Kumar Sharma, Emilie Alirol, Anup Ghimire, Suman Shrestha, Rupesh Jha, Surya B. Parajuli, Deekshya Shrestha, Surya Jyoti Shrestha, Amir Bista, David Warrell, Ulrich Kuch, Francois Chappuis, Walter Robert John Taylor

“…Of 155 envenomed patients who received ≥ 1 antivenom dose, 13 (8.4%), three children (aged 5−11 years) and 10 adults (18−52 years), developed clinical features consistent with severe ARA, including six with overlapping signs of severe envenoming. …”
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Endometrial factors in the implantation failure spectrum: protocol of a MUltidisciplinary observational cohort study in women with Repeated Implantation failure and recurrent Misca... by Servaas Morré, Ron van Golde, Andrea Romano, Linda Stevens Brentjens, Denise Habets, Janneke Den Hartog, Salwan Al-Nasiry, Lotte Wieten, Aafke Van Montfoort

“…Our objective is to elucidate whether there is a difference in endometrial receptivity parameters (ie, steroid metabolism, uNK cells and the microbiome) between women aged 18–38 years with reproductive failure (RIF and RM), and fertile controls.Methods and analysis Single-centre, observational cohort study. …”
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Influence of the Multifunctional Biological Product Phytop 26.82 on the Growth and Development of Seed Potatoes by Vladislava Maslennikova, Vera Tsvetkova, Andrey Petrov, Rinat Galeev, Maxim Shulga, Natalia Gavrilets, Sergey Ryumkin, Anastasia Shulga, Evgeniy Ryadskiy, Kristina Koloshina, Inga Ryumkina

“…The authors revealed the degree of influence of the natural effect Phytop 26.82 on the Colorado potato beetle’s larvae of different ages. The larvae were counted on the 5th, 7th, and 10th days of the experiment. …”
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Local application of sodium thiosulfate as an otoprotectant for cisplatin-exposed patients – A narrative literature review to explore the potential benefit for children with cancer... by Nienke Streefkerk, Amirhossein Masroor, James I. Geller, Martine van Grotel, Marc Ansari, Eric Bouffet, Archie Bleyer, Brice Fresnau, Michael Sullivan, Alwin D.R. Huitema, Alexander E. Hoetink, Per Kogner, Rudolf Maibach, Allison F. O’Neill, Vassilios Papadakis, Kaukab M. Rajput, Gareth J. Veal, Penelope R. Brock, Annelot J.M. Meijer, Marry M. van den Heuvel-Eibrink

“…Methods: A PubMed search, focused on clinical and pre-clinical efficacy, safety, and pharmacokinetics of local STS application in cisplatin-exposed subjects of all ages was performed. Findings: From 256 studies, ten studies met the inclusion criteria, including seven preclinical studies, and three clinical studies. …”
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Evaluation of efficacy and safety of generic tacrolimus (Suprotac®) compared to reference tacrolimus (Prograf^®) in kidney transplantation: a phase IV study by Behzad Einollahi, Mohsen Nafar, Mohammad Javanbakht, Amirhesam Alirezaei, Jalal Azmandian, Abbas Etminan, Mohammad Reza Ardalan, Jalal Etemadi, Roghayeh Akbari, Vahid Pourfarziani, Seyed Sadraddin Rasi Hashemi, Seyed Maryam Rahbar, Shahrzad Shahidi, Javid Safa, Hamid Tayyebi Khosroshahi, Sima Abedi Azar, Shahrzad Ossareh, Abdolamir Atapour, Bahareh Marghoob, Fatemeh Nazemian, Hamidreza Kafi, Araz Sabzvari

“…Methods: In this two-armed, open-label, parallel, active-controlled, and cohort study, de novo kidney transplant recipients aging 18 to 65 years were prescribed Suprotac® or Prograf® as part of the immunosuppressant protocol. …”
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Heart rate cost as a tool for monitoring recovery between acute training sessions by José Morais Souto Filho, Milton Rocha de Moraes, Patrício Lopes de Araújo Leite, Larissa Alves Maciel, Andréa Cândida Arruda Andrade Rezende, Thiago dos Santos Rosa, Fabiana Andrade Machado, Sergio Rodrigues Moreira, Ricardo Yukio Assano, Marcelo Magalhães Sales, Herbert Gustavo Simões

“…Methods Fifteen male recreational runners (aged 18–31 years) participated in this investigation. …”
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Evaluating the implementation of a multicomponent intervention to improve faecal immunochemical test-based (FIT) colorectal cancer screening in primary care by Kamala Adhikari, James Whitworth, Gary F Teare, Muhammad Kashif Mughal, Danica Hignell, Barbara Moysey, Jawad Chishtie

“…The faecal immunochemical test (FIT) is recommended for screening people aged 50–74 years at average risk of CRC in Alberta, Canada. …”
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The Validity of a Smartphone-Based Application for Assessing Cognitive Function in the Elderly by Jin-Young Min, Duri Kim, Hana Jang, Hyunjoo Kim, Soojin Kim, Seungbo Lee, Yae-eun Seo, Ye-jin Kim, Jong-yoon Kim, Kyoung-Bok Min

“…<b>Methods:</b> We recruited 88 study participants aged over 60. They completed two cognitive tests with the Montreal Cognitive Assessment (MoCA), a validated paper-and-pencil cognitive screening tool, and Brain OK, a smartphone-based cognitive testing application. …”
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Towards PErsonalised PRognosis for children with traumatic brain injury: the PEPR study protocol by Jaap Oosterlaan, Marsh Königs, Job B M van Woensel, Marc Engelen, Marjan E Steenweg, Petra J W Pouwels, Cece C Kooper, Hilgo Bruining, Arne Popma, Dennis R Buis, Maayke Hunfeld

“…In addition, the potential added value of advanced neuroimaging data and the use of machine learning algorithms in the development of prognostic models will be assessed.Methods and analysis 210 children aged 4–18 years diagnosed with mild-to-severe TBI will be prospectively recruited from a research network of Dutch hospitals. …”
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Optimizing athletic engagement and performance of obese students: an adaptive approach through basketball in physical education by Oumayma Slimi, Oumayma Slimi, Antonella Muscella, Santo Marsigliante, Mourad Bahloul, Georgian Badicu, Abdullah F. Alghannam, Fatma Hilal Yagin

“…This study evaluated the effects of a 7-week adapted basketball program on the performance and athletic engagement of students with obesity.MethodsSixty-two students with obesity (23 boys, 39 girls, aged 15-17) were randomly assigned to an experimental group (EG, n = 30; 11 boys, 19 girls) participating in adapted basketball sessions or a control group (CG, n = 32; 12 boys, 20 girls) attending standard basketball lessons. …”
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Baricitinib treatment for hospitalized patients with severe COVID-19 on invasive mechanical ventilation: a propensity score-matched and retrospective analysis by Yanxiong Mao, Anyi Guo, Ying Zhang, Jianxing Lai, Dian Yuan, Hao Zhang, Wenqi Diao, Weisong Chen, Fugui Yan

“…But in severe COVID-19 patients, the effectiveness of baricitinib is still controversial.MethodsA propensity score-matched and retrospective study was conducted to evaluate the effectiveness of baricitinib in severe COVID-19 patients requiring invasive mechanical ventilation (IMV).ResultsA total number of 48 patients treated with baricitinib were included, and 48 patients were assigned to control group by propensity score matching. The mean ages were high in both group (baricitinib group vs. control group: 78.80 ± 9.04 vs. 82.57 ± 9.27), and most were unvaccinated (62.5% vs. 66.7%. …”
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Influence of intravenous lidocaine infusion on haemodynamic response to tracheal intubation and metabolic-hormonal responses during laparoscopic procedures in children: a randomise... by Maciej Kaszyński, Alicja Kuczerowska, Justyna Pietrzyk, Piotr Sawicki, Paweł Witt, Barbara Stankiewicz, Marek Darowski, Izabela Pągowska-Klimek

“…Methods A single-centre, parallel, double-masked, randomised, placebo-controlled trial. 132 patients, aged 18 months to 18 years, with no contraindications to lidocaine administration and qualified for laparoscopic appendectomy were enrolled. …”
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Prescription of Strong Opioids in Chronic Non-Cancer Pain in the Province of Valladolid (Spain) by Rodrigo Enríquez de Salamanca Gambara, Ana María Sierra Santos, Ana María Ruiz San Pedro, Federico Montero Cuadrado, Irene Muñoz León, Miguel Ángel Castro Villamor, Alicia Córdoba Romero, Ana María Del Olmo Tornero, Lucía Pérez Pérez, León Morales-Quezada

“…Of the patients, 62.4% were aged 70 or older, 39.8% lived in rural areas, and 9.9% resided in nursing homes. …”
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Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner by Wenxiang Qing, Huimin Chen, Xin Ma, Jie Chen, Yuan Le, Hui Chen, Jianhua Tong, Kaiming Duan, Daqing Ma, Wen Ouyang, Jianbin Tong

“…Chronic stress can result in various conditions, including psychological disorders, neurodegenerative diseases, and accelerated brain aging. Gut dysbiosis potentially contributes to stress-related brain disorders in individuals with chronic stress. …”
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