C-reactive protein testing in primary care and antibiotic use in children with acute respiratory tract infections in Kyrgyzstan: an open-label, individually randomised, controlled... by Elvira Isaeva, Joakim Bloch, Azamat Akylbekov, Robert L. Skov, Anja Poulsen, Jørgen A.L. Kurtzhals, Susanne Reventlow, Nandini Sreenivasan, Maamed Mademilov, Volkert D. Siersma, Talant Sooronbaev, Jesper Kjærgaard, Rune M. Aabenhus

“…Methods: In this open label individually randomised controlled trial, children aged 6 months to 12 years with ARTI in primary care settings were assigned to receive either standard care or standard care plus CRP testing. …”
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Clinical characteristics and outcomes of children with COVID-19 in pediatric intensive care units during the Omicron wave in Taiwan by Jeng-Hung Wu, Ching-Chia Wang, Frank Leigh Lu, Shu-Chien Huang, Ting-Yu Yen, Chun-Yi Lu, Luan-Yin Chang, En-Ting Wu

“…Methods: Medical records were retrospectively collected from patients with COVID-19 (aged <18 years) admitted to our PICU from April 2022–March 2023. …”
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Technical Proficiency Analysis in Table Tennis: A Comparative Study Between Advanced and Intermediate Players by Benny Aprial, Denny Setyawan, George Danut Mocanu, Candra Brema Tarigan, Ghulam Mustafa, John Michael D. Aquino, Bilal Azmi Sarıtaş

“…The research involved 40 participants (20 advanced players with 5+ years of competitive experience and 20 intermediate players with 2-4 years of experience) aged 18-25 years. Over a three-month period, participants underwent systematic evaluation of their technical skills, including basic stroke accuracy, biomechanical efficiency, and tactical adaptability. …”
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External Validity of the Novel Surrogate Measures for Occipitocervical Alignment by Ahmadreza Mirbolook, Masoomeh Raoufi, Yeganeh Yousefifar, Mobin Forghan, Mohammad Sadegh Fakhari, Mohammadreza Bozorgmanesh

“…We retrospectively studied 274 lateral cervical radiographs of patients aging 1 to 87 years who had no cervical pathology evident on X-ray. …”
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Cholesterol, triglycerides, HDL, and nitric oxide as determinants of resting heart rate variability in non-hospitalized mild post-COVID individuals: a cross-sectional study by Lucivalda Viegas de Almeida, Aldair Darlan Santos-de-Araújo, Luís Cláudio Nascimento da Silva, Patricia Martins Santos, Mariana Campos Maia, Victória Pereira Frutuoso, Daniel Santos Rocha, Adriana Sousa Rêgo, Daniela Bassi-Dibai

“…Individuals of both sexes, aged ≥ 18 years, who tested positive for SARS-CoV-2 according to the RT-PCR test, without the need for hospitalization, were included. …”
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Association between sleep disorder and anhedonia in adolescence with major depressive disorder: the mediating effect of stress by Xinxin Zhao, Hongzhe Ma, Ning Li, Wenjun Wu, Xinxu Ma, Xinxin Zhang, Wenming Liu, Lei Shang, Huaning Wang, Hailong Dong, Chen Li, Guangchao Zhao, Min Cai

“…Methods This is a cross-sectional study that includes 200 adolescents suffered from MDD between the ages of 12–17. We use Spearman’s test to explore the relationship among main variables. …”
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Relationship between Obesity and Cognitive Function in Young Women: The Food, Mood and Mind Study by Rebecca L. Cook, Nicholas J. O’Dwyer, Cheyne E. Donges, Helen M. Parker, Hoi Lun Cheng, Katharine S. Steinbeck, Eka P. Cox, Janet L. Franklin, Manohar L. Garg, Kieron B. Rooney, Helen T. O’Connor

“…Results. 299 women (NW: n = 157; OB: n = 142) aged 25.8 ± 5.1 y were enrolled. Cognition scores were within normal range (±1 z-score), but OB had lower attention (NW: 0.31 ± 1.38; OB: −0.25 ± 1.39; ES: 0.41, CI: 0.17–0.64; p<0.001) and higher impulsivity (NW: 0.36 ± 1.14; OB: −0.07 ± 1.07; ES: 0.39, CI: 0.15–0.62; p=0.033). …”
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The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta by Kunhua ZHENG, Longfei XIAO, Naihan YUAN, Xihui SHENG, Xiaolong QI, Yingqiu WANG, Chang CHEN, Kaijun GUO, Lin YANG, Bingying LIU, Xiangguo WANG

“…Cotyledon villi were collected from bovine placentas at different gestational ages, and the localization and expression of IGF2, IGF2R, and exosomal marker proteins were detected. …”
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Higher oxidative balance score is associated with a decreased risk of infertility: an analysis of NHANES 2013–2020 by Mingjun Ma, Huanying Xu, Huanying Xu, Kexin Wang, Yanfen Chen, Ting Pan, Qiaoling Zhu, Qiaoling Zhu

“…However, limited studies have explored the relationship between OBS and infertility.MethodsWe performed a cross-sectional study including 2,664 women aged 20–45 years, based on data from the 2013–2020 National Health and Nutrition Examination Survey (NHANES). …”
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Twelve-month follow-up of a controlled trial of a brief behavioural intervention to reduce psychological distress in young adolescent Syrian refugees by Richard A. Bryant, Rand Habashneh, Maha Ghatasheh, Aiysha Malik, Ibrahim Said Aqel, Katie S. Dawson, Sarah Watts, Mark J. D. Jordans, Felicity L. Brown, Mark van Ommeren, Aemal Akhtar

“…Methods In this single-blind, parallel, controlled trial, Syrian refugees aged 10-14 years in Jordan who screened positive for psychological distress were randomised to receive either EASE or enhanced usual care (EUC). …”
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Use of Complementary and Alternative Medicine Practices in Patients Admitted to The Pediatric Neurology Outpatient Clinic by Deniz Yüksel, Ergin Atasoy, Ülkühan Öztoprak, Erhan Aksoy, Fatih Mehmet Akif Özdemir, Halil Celik, Nesrin Ceylan

“…Methods: This prospective survey study was conducted with the parents of 300 pediatric patients aged between 6 months and 18 years, who were being treated at the Child Neurology Clinic between March 1st and May 30th, 2020. …”
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Polymorphisms in the leptin gene and their role in adolescent obesity and metabolic health by Raden Ayu Tanzila, Irfannuddin Irfannuddin, Yudianita Kesuma, Iche Andriyani Liberty, Miranti Dwi Hartanti, Ni Made Elva Mayasari, Wieke Anggraini, Liza Chairani, Thia Prameswarie, Indri Ramayanti, Wulan Aristi, Delvi Larasari

“…A total of 50 blood samples from adolescents (aged 10-18 years) were analyzed in this study. Standard laboratory protocols for serum lipid measurements, deoxyribonucleic acid (DNA) extraction, allele analysis by polymerase chain reaction (PCR), and LEP and insulin analysis by enzyme-linked immunosorbent assay (ELISA) were employed. …”
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The effects of war-related experiences on mental health symptoms of individuals living in conflict zones: a longitudinal study by Doron Amsalem, Shilat Haim-Nachum, Amit Lazarov, Yossi Levi-Belz, John C. Markowitz, Maja Bergman, Alexandra Klein Rafaeli, Lisa A. Brenner, Nitsa Nacasch, Milton L. Wainberg, Ido Lurie, Shlomo Mendlovic, Yuval Neria

“…This three-wave online survey study assessed mental health symptoms in a sample of 1052 individuals, aged 18–40, residing in conflict zones in Israel from February 2024 (day 1), through March 2024 (day 30), to May 2024 (day 90). …”
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Damoctocog Alfa Pegol, a PEGylated B-domain Deleted Recombinant Extended Half-life Factor VIII for the Treatment of Hemophilia A: A Product Review by Mark T. Reding, Shadan Lalezari, Gili Kenet, Giovanni Di Minno, Jonathan Ducore, Alexander Solms, Anita Shah, Pål André Holme, Lone H. Poulsen, Karina Meijer, Mindy Simpson, Maria Elisa Mancuso

“…Abstract Damoctocog alfa pegol (BAY 94-9027, Jivi®), is a site-specifically PEGylated, extended half-life recombinant factor VIII (FVIII) that is approved in several European and non-European countries for on-demand treatment and prophylaxis of bleeding in previously treated patients aged ≥ 12 years with hemophilia A. Reliable measurements can be obtained using most one-stage and chromogenic FVIII assays over a wide concentration range. …”
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Exploring Prevalence and Sociodemographic Factors Associated With Smoking Among Malaysian Adults: A Cross‐ Sectional Study by Mohd Hasni Ja'afar, Rosnah Ismail, Zaleha Md Isa, Azmi Mohd Tamil, Noor Hassim Ismail, Nafiza Mat Nasir, Nik Munirah Nasir, Nurul Hafiza Ab Razak, Najihah Zainol Abidin, Andrew Mente, Khairul Hazdi Yusof

“…Methods This study was carried out in urban and rural communities with adults aged between 35 and 70 years using purposive sampling. …”
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Reduced functional independence and multimorbidity increases the risk of severe infection among older patients with Omicron: a multicenter retrospective cohort study by Wan Yu, Runnian Huang, Shuning Sun, Li Bu, Xin Chen, Yunhua Di, Shuwu Lin, Qian Li, Yang Yang, Xingyue Ye, Wenxu Wang, Rui Ren, Linze Xi, Ru Zhang, Yi Li, Xin Li, Tianbo Hou, Zibo Ning, Yang Peng, Difei Wang

“…Methods This is a multicentre, retrospective cohort study in northeastern China. Patients aged ≥ 60 years, who were diagnosed with COVID-19 at the time of admission or during hospitalisation. …”
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MATN3 Gene Polymorphism Is Associated with Osteoarthritis in Chinese Han Population: A Community-Based Case-Control Study by Jiaao Gu, Jiesheng Rong, Fulin Guan, Liying Jiang, Shuqing Tao, Guofa Guan, Tianzun Tao

“…A total of 732 community residents aged 40–84 years participated in the community-based study in Northeast China. …”
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Longer-term safety and efficacy of baricitinib for atopic dermatitis in pediatric patients 2 to <18 years old: a randomized clinical trial of extended treatment to 3.6 years by Andreas Wollenberg, Masanori Ikeda, Chia-Yu Chu, Lawrence F. Eichenfield, Marieke M. B. Seyger, Apurva Prakash, Robinette Angle, Danting Zhu, Marco Pontes, Amy S. Paller

“…Background Baricitinib, an oral selective Janus kinase inhibitor, improved clinical signs and symptoms of moderate-to-severe atopic dermatitis (AD) at week 16 in the phase 3 pediatric study BREEZE-AD-PEDS.Objective To assess longer-term efficacy and safety of baricitinib in pediatric patients aged 2 to <18 years.Methods In BREEZE-AD-PEDS long-term extension, responders and partial responders (validated Investigator Global Assessment-Atopic Dermatitis [vIGA-AD®] 0/1/2) at Week 16 remained on double-blind treatment to which they were randomized (placebo, baricitinib [1-mg equivalent, 2-mg equivalent, or 4-mg equivalent); non-responders (vIGA-AD 3 or 4) at Week 16 transitioned to open-label baricitinib 4-mg equivalent. …”
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Tramadol use and incident dementia in older adults with musculoskeletal pain: a population-based retrospective cohort study by Si Nae Oh, Hye Jun Kim, Jae Yong Shim, Kyuwoong Kim, Seogsong Jeong, Sun Jae Park, Sang Hyun Lee, Joong Won Ha, Sang Min Park

“…This population-based retrospective cohort study using the Korean National Health Insurance Service database included a total of 1,865,827 older adult patients aged 60 years or older with common musculoskeletal pain between January 1, 2003, and December 31, 2007. …”
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Nutritional intake of micronutrient and macronutrient and type 2 diabetes: machine learning schemes by Mohammad Rashidmayvan, Amin Mansoori, Elahe Derakhshan-Nezhad, Davoud Tanbakuchi, Fatemeh Sangin, Maryam Mohammadi-Bajgiran, Malihehsadat Abedsaeidi, Sara Ghazizadeh, MohammadReza Mohammad Taghizadeh Sarabi, Ali Rezaee, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…The study population comprised 9704 individuals aged 35–65 years were enrolled regarding their T2D status, and those with T2D history. 15% of individuals are diabetic and 85% of them are non-diabetic. …”
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