Comparing the Prognostic Value of PTEN and Akt Expression with the Mitotic Activity Index in Adjuvant Chemotherapy-Treated Node-Negative Breast Cancer patients aged <55 years by Emiel A. M. Janssen, Håvard Søiland, Ivar Skaland, Einar Gudlaugson, Kjell H. Kjellevold, Arne Nysted, Jon-Arne Søreide, Jan P. A. Baak

“…Conclusions: In T1−3N0M0 adjuvant CMF-treated breast cancer patients aged <55 years, MAI was the strongest survival predictor. …”
Get full text

Heterogeneous association of health with patient and general practice characteristics by region, age and chronic condition: pooled cross-sectional study of patient-level data from England by Hugh Gravelle, Yan Feng, Vladimir Sergeevich Gordeev

“…White ethnicity is associated with worse health up to age 64 and better health from age 65, with better health in five of the eight chronic condition samples, and in the regional samples except for London and Yorkshire and Humber regions. …”
Get full text

Age, Body Mass Index, and Waist-to-Hip Ratio Related Changes in Insulin Secretion  and  Insulin Sensitivity in Women  with Polycystic Ovary Syndrome: Minimal Model Analyses by Mirjana Šumarac-Dumanović, Danica Stamenković-Pejković, Danka Jeremić, Janko Dumanović, Vesna Mandić-Marković, Miloš Žarković, Dragan Micić

“…There was a significant interaction between disease (PCOS), BMI, and WHR on Si as well as between age and PCOS on AIRG. Thus, patients below the age of 25 with PCOS showed enhanced AIRG (89.5 ± 7.1 vs. 65.1 ± 6.7, p<0.05) and decreased Si (2.43 ± 0.25 vs. 4.52 ± 0.62, p<0.05) compared to age-matched controls. …”
Get full text

Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (N = 19) by Carlijn de Roos, Julia Offermans, Samantha Bouwmeester, Ramón Lindauer, Frederike Scheper

“…Background: Trauma exposure is common in (pre) school-aged children and around one-fifth of exposed children meet the criteria for post-traumatic stress disorder (PTSD). …”
Get full text

Architecture antique entre âge du Fer et époque impériale en Provence : les piliers du site de Château-Bas à Vernègues by Sandrine Agusta-Boularot, Raphaël Golosetti

“…The originality of these pieces should perhaps be sought in the copying and adaptation of Italic architectural features (Attic base, Tuscan capital) to a particular form of monument (pillar, stela) and type of decoration (snake) attested in Provence in the Late Iron Age.…”
Get full text

Older Age Is Associated with Decreased Levels of VDR, CYP27B1, and CYP24A1 and Increased Levels of PTH in Human Parathyroid Glands by Yi Jiang, Liyan Liao, Jina Li, Larry Wang, Zhongjian Xie

“…Previous studies have shown that the serum level of intact parathyroid hormone (iPTH) increases with age. We hypothesized that the expression of CYP27B1 or VDR in parathyroid glands decreases with age, which might account for the increased serum levels of iPTH due to decreased suppression of parathyroid hormone (PTH) secretion by 1,25(OH)2D in older people. …”
Get full text

A Meta-Analysis of Studies Evaluating Visual and Anatomical Outcomes in Patients with Treatment Resistant Neovascular Age-Related Macular Degeneration following Switching to Treatment with Aflibercept by Sophie Seguin-Greenstein, Sue Lightman, Oren Tomkins-Netzer

“…With the introduction of aflibercept, eyes with neovascular age-related macular degeneration (AMD) not responding well to injections of ranibizumab or bevacizumab can be switched to treatment with aflibercept. …”
Get full text

Global burden and cross-country inequalities of nutritional deficiencies in adults aged 65 years and older, 1990–2021: population-based study using the GBD 2021 by Shuang Liang, Shao-Zhi Xi, Jia-Yi Liu, Gui-Chun Tang, Wei-Guang Zhang, Xin-Ru Guo, Chen Yang, Chun Zhang, Guang-Yan Cai

Subjects: Get full text

Factors Predicting Insecticide-Treated Bednet Use among Children under Age Five in Female-Headed Households in Ghana: An Analysis of the 2019 Malaria Indicator Survey by Desmond Klu, Grace Frempong Afrifa-Anane, Michael Larbi Odame

“…However, children living with older female household heads aged 70 years and above (aOR = 0.12; CI: 0.07–0.21), 60–69 years (aOR = 0.23; CI: 0.14–0.38), and those residing in urban areas (aOR = 0.59; CI: 0.43–0.82) were less probable to sleep under treated bednet. …”
Get full text

Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…Objectives The type of electronic nicotine delivery system (ENDS) used by different age groups may be associated with ENDS and cigarette use behaviours. …”
Get full text

Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials by Jianyu Gan, Jiya He, Kaixiang Zhou, Zhangyuting Shang, Gengxin Dong, Dapeng Bao, Junhong Zhou

Subjects: Get full text

Constraints of S–Pb–Sr Isotope Compositions and Rb–Sr Isotopic Age on the Origin of the Laoyingqing Noncarbonate-Hosted Pb–Zn Deposit in the Kunyang Group, SW China by Hongsheng Gong, Runsheng Han, Peng Wu, Gang Chen, Lingjie Li

“…First, the Rb–Sr isochron age of sphalerite is 209.8±5.2 million years (Ma), consistent with the ages of most Pb–Zn deposits in the SYGT (approximately 200Ma), thereby potentially indicating that these Pb–Zn deposits may have been formed synchronously during the late Indosinian orogeny. …”
Get full text

A more accurate relationship between serum androgen and metabolism among healthy, nonobese, reproductive-age women based on liquid chromatography-tandem mass spectrometry by Sha Ye, Yepei Huang, Yi Lu, Xiaoyan Li, Meiling Ye, Hongyu Lu, Junhua Shi, Jian Huang, Hong Cai

“…This study explored a more precise association between androgens and glycolipid metabolism in healthy women of different ages. Body mass index (BMI), waist circumference (WC), and waist-to-hip ratio were used as body fat indicators. …”
Get full text

Anti-vascular Endothelial Growth Factor Outpatient Treatment Patterns in Patients with Exudative Age-related Macular Degeneration from a Japanese Hospital Claims Database by Tomohiro Iida, Aya Narimatsu, Kenji Adachi, Edward CY Wang

“…**Purpose:** To identify outpatient treatment patterns of patients with exudative age-related macular degeneration (AMD) who received approved anti–vascular endothelial growth factor (VEGF) therapy, using real-world data from hospitals in Japan. …”
Get full text

Christian Felix Weiße’s Poetry in Latvian and Estonian Literature by Ave Mattheus, Pauls Daija

Subjects: Get full text

Mosaic loss of the Y chromosome in human neurodegenerative and oncological diseases by I. L. Kuznetsova, L. I. Uralsky, T. V. Tyazhelova, T. V. Andreeva, E. I. Rogaev

Subjects: Get full text

Business philosophy during digital transformation in wartime conditions. The case of Ukraine in critical perspective by Yaroslav Pushak, Nataliia Trushkina, Vitaliy Flyak, Iryna Bezpalko

Subjects: “…Business in the digital age…”
Get full text

UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases by Marco Capó, Silvia Vitali, Georgios Athanasiou, Nicole Cusimano, Daniel García, Garth Cruickshank, Bipin Patel

Subjects: “…Brain age prediction…”
Get full text

Histoire et archéologie d’un chef-lieu de pagus en Bourgogne : recherches en cours sur le site de la « Montagne de Saint-Laurent » à Mesmont (Côte d’Or) by Antoine Guicheteau

Subjects: Get full text

Investigating LiDAR Metrics for Old-Growth Beech- and Spruce-Dominated Forest Identification in Central Europe by Devara P. Adiningrat, Andrew Skidmore, Michael Schlund, Tiejun Wang, Haidi Abdullah, Marco Heurich

Subjects: “…stand age…”
Get full text