Cellular rejuvenation protects neurons from inflammation-mediated cell death by Sienna S. Drake, Abdulshakour Mohammadnia, Aliyah Zaman, Christine Gianfelice, Kali Heale, Adam M.R. Groh, Elizabeth M.-L. Hua, Matthew A. Hintermayer, Yuancheng Ryan Lu, David Gosselin, Stephanie Zandee, Alexandre Prat, Jo Anne Stratton, David A. Sinclair, Alyson E. Fournier

“…Pathway analysis identifies a transcriptional signature reminiscent of aged RGCs with some senescent features, with a comparable signature present in neurons from patients with MS. …”
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Apert Syndrome. Case Report by Ninecta Pérez Breña, Francisco Amed Abad Aguiar, Dunia Reyes Hernández, Yamil González Martínez

“…The case of a white female aged 7 is evaluated in the Primary Care Service of the Barrio Adentro medical mission in Nueva Esparta state, Republic of Venezuela. …”
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Correlations of vascular cognitive impairment with brain-derived neurotrophic factor and trace elements by Zhou Rong, Lei Chao, Zhi Haiyang

“…Cognitive impairment has become one of the major public health problems due to population aging and the increased morbidity associated with stroke. …”
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Quantitative Physiologic MRI Combined with Feature Engineering for Developing Machine Learning-Based Prediction Models to Distinguish Glioblastomas from Single Brain Metastases by Seyyed Ali Hosseini, Stijn Servaes, Brandon Hall, Sourav Bhaduri, Archith Rajan, Pedro Rosa-Neto, Steven Brem, Laurie A. Loevner, Suyash Mohan, Sanjeev Chawla

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Beta-hydroxy-beta-methylbutyrate (HMB) improves daily activity and whole-body protein metabolism in Duchenne muscular dystrophy dogs: a pilot study by Peter P. Nghiem, Alexis M. Rutledge, Kyle Tehas, Corine Kaderli, Meredith Poling, Sidney Arnim, Vitaliy Dernov, Celine van Sas, Macie L. Mackey, Gabriella A. M. ten Have, Mariëlle P. K. J. Engelen, Nicolaas E. P. Deutz

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Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

“…Abstract Background Both the expression and activities of LINE-1 (L1) retrotransposons are known to occur in numerous cell-types and are implicated in pathobiological contexts such as aging-related inflammation, autoimmunity, and in cancers. …”
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Temperament Upregulates Mitochondrial Enzymes and Negatively Affects Myofibrillar Fragmentation in Beef of Excitable <i>Bos taurus indicus</i> Cattle by Patricia Maloso Ramos, Eduardo Francisquine Delgado, Ana Cláudia da Silva, Nara Regina Brandão Cônsolo, Vinicius Laerte Silva Herreira, João Marcos Bovetto de Campos Valim, Fernanda Maria Marins Ocampos, Luiz Alberto Colnago, Saulo da Luz e Silva

“…Conclusions: Altogether, results emphasized the upregulation of mitochondrial enzymes and reduced tenderization as determinants of inferior beef quality after prolonged aging in excitable cattle.…”
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Serum 25(OH)D Level and Parathyroid Hormone in Chinese Adult Population: A Cross-Sectional Study in Guiyang Urban Community from Southeast of China by Zhang Qiao, Shi Li-xing, Peng Nian-chun, Xu Shu-jing, Zhang Miao, Li Hong, Zhuang Hui-jun, Gong Ming-xian, Zhang Song, Wang Rui, Hu Ying, Zhang Jing-lu, Chen Shuang

“…Results.The mean serum 25(OH)D level was (20.4 ± 9.0) ng/mL and the highest level among participants aged 40–59 years (22.8 ng/mL). The mean serum PTH level was (32.1 ± 13.7) pg/mL and the lowest level among participants aged 40–50 years (30.8 ng/mL). …”
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Design of a novel Cu-Cr-X alloy with high strength and high electrical conductivity based on mechanical learning by Yunqing Zhu, Yicheng Cao, Lijun Peng, Qian Yu, Zhen Yang, Zengde Li, Junsheng Wu, Haofeng Xie

“…With the increase of aging temperature, the bcc structure Cr phase gradually replaces the fine fcc-Cr phase and exhibited a higher coarsening rate. …”
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Helicobacter pylori antibacterial resistance patterns in Latvia: results from the Gistar pilot study by D. Rudzīte, R. Vangravs, I. Daugule, Ģ. Šķenders, I. Poļaka, A. Vanags, J. Atstupens, I. Tolmanis, P. Pūpola, Y. Tarasenko, J. Park

“…The aim of the study is to evaluate the primary susceptibility of H. pylori to antibiotics used in recommended eradication regimens for the middle-aged population in Latvia. Materials and Methods: H. pylori antibiotic resistance was assessed in asymptomatic individuals aged 40-64 years, recruited as part of the GISTAR pilot study. …”
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Surveillance on the coverage of herpes zoster vaccine and post-marketing adverse events in Jiangsu province, China by Xiang Sun, Lei Zhang, Tingting Zhang, Jinning Sun, Yan Xu, Li Liu, Yuan Bao Liu, Ran Hu, YaLi Fu, Zhiguo Wang, Hui Sun

“…Despite the proven safety profile of the HZ vaccine, its coverage remains significantly low among individuals aged 50 years and above in Jiangsu Province, China as of 2023. …”
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Metformin reverts aortic calcifications and elastin loss induced by an experimental metabolic syndrome by Lucas Streckwall, Nancy Martini, Claudia Sedlinsky, León Schurman, María Virginia Gangoiti, Antonio Desmond McCarthy

“…All these effects were reverted by MET cotreatment (FM group). In vitro, AGEs-modified bovine serum albumin upregulated RAGE expression of control VSMCs, and this was prevented by MET in an AMP kinase-dependent manner. …”
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Protective effects of seed oil from Nicotiana tabacum L. On D-galactose induced liver and brain damages of mice by regulating PI3K/Akt/Nrf2 signaling pathway by Ji Gu, Yongchao Wang, Shanshan Xiao, Yunye Zheng, Zhengxuan Wang, Yaping Liu, Limeng Zhang, Guiguang Cheng

“…Combined with GC/MS component analysis and network pharmacology prediction, the aging related PI3K/Akt/Nrf2 pathway was found for further verification. …”
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Prevalence of Gastrointestinal Protozoa on Bali Cattle in Lopok Sub-District, Sumbawa District by Aldi Hamdani, Nunuk Dyah Retno Lastuti, Yeni Dhamayanti, Setiawan Koesdarto, Agus Sunarso, Poedji Hastutiek

“…This study found 59 samples (59%) were infected by one type of protozoa, 3 samples (3%) were infected by two types of protozoa. Cattle aged 0-6 months (81%) had a higher prevalence rate and were more susceptible to protozoal infections than cows aged 7 months – 2 years (70.3%) and more than 2 years (45.2%).…”
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The experience of mothers of autistic children with a pathological demand avoidance profile: an interpretative phenomenological analysis by Sam Curtis, Elizabeth Izett

“…Methods Semi-structured interviews were completed with ten parents of autistic children with a pathological demand avoidance profile, aged between 5 and 11 years (M = 8.5, SD = 1.90). …”
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Analysis of the Distribution of Forest Management Areas by the Forest Environmental Tax in Ishikawa Prefecture, Japan by Yuta Uchiyama, Ryo Kohsaka

“…From the result, positive correlations are identified between the distribution of management areas and natural hazard areas and between the distribution of management areas and areas with high aging rates.…”
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What was Killing Babies in Sundsvall? A Study of Infant Mortality Patterns Using Individual Level Cause of Death Data, 1860–1892 by Maria Hiltunen Maltesdotter, Sören Edvinsson

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L’usure et la défiguration chez Dickens by Marie-Amélie Coste

“…Although traumas cause sudden and premature ageing, often shown in the characters’ disfiguring, it also has beneficial effects. …”
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Applying a Common-Sense Approach to Fighting Obesity by Jessica Y. Breland, Ashley M. Fox, Carol R. Horowitz, Howard Leventhal

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Failure Mechanism and Mechanical Properties of a Retard-Bonded Prestressed Concrete Girder While Curing by Wei-ning Sui, Zi-yi Wang, Zhong-hua Zhao, Zhan-fei Wang

“…The measurements include the following: the retard-bonded agent ages versus the load-carrying capacity of the girder, the deflection of girder, the strain distribution at key cross sections through the girder, the pressure at PT tensile and anchoring ends, crack distribution, and so on. …”
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