A novel lncRNA AC112721.1 promotes the progression of triple-negative breast cancer by directly binding to THBS1 and regulating miR-491-5p/C2CD2L axis by Ping Ma, Shiyao Kang, Huimin Li, Ming Li, Yuan Zhao, Hongjun Yuan, Jianyu Pang, Wenru Tang, Miaomiao Sheng

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Colour Stability and Lipid Oxidation of Beef Longissimus Lumborum under Different Packaging Conditions by Bonny Dadji Stéphane Serge, Li Xin, Li Zheng, Li Meng, Du Manting, Gao Lingling, Zhang Dequan

“…Beef under vacuum packaging showed higher a* values on 7, 14, and 21 days of ageing and lower L* values on 14 and 21 days of ageing than beef in MAP (p<0.05). …”
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Long-term Cd remediation mechanisms and potential risks in soil with biochar application under dry-wet cycling at different soil moisture levels by Shuang Huang, Zhuowen Meng, Jingwei Wu, Lei Xin, Qin Zhao

“…The results showed that Cd adsorbed by biochar in soils during long-term ageing first underwent rapid adsorption (over 0–5 years of simulated ageing), then equilibrium stabilization (over 5–20 years of simulated ageing), and finally slight re-released (over 20–30 years of simulated ageing). …”
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Effects of Low-Dose Testosterone Undecanoate Treatment on Bone Mineral Density and Bone Turnover Markers in Elderly Male Osteoporosis with Low Serum Testosterone by Yan-Jiao Wang, Jun-Kun Zhan, Wu Huang, Yi Wang, Yuan Liu, Sha Wang, Pan Tan, Zhi-Yong Tang, You-Shuo Liu

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Development and Mixed-Methods Evaluation of a Pain Assessment Video Training Program for Long-Term Care Staff by Michelle M Gagnon, Thomas Hadjistavropoulos, Jaime Williams

“…Insufficient pain education and inaccurate beliefs about the nature of pain and aging have been identified as possible contributors. …”
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Increased matrix metalloproteinase-1 expression by coexposure to UVA and cigarette sidestream smoke and contribution of histone acetylation by Ryoma Ito, Yukako Komaki, Yuko Ibuki

“…Abstract Background Skin is exposed to various environmental factors throughout life, and some of these factors are known to contribute to skin aging. Long-term solar UV exposure is a well-known cause of skin aging, as is cigarette smoke, which contains a number of chemicals. …”
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Cardiac Resynchronization Therapy Outcomes in Type 2 Diabetic Patients: Role of MicroRNA Changes by Celestino Sardu, Michelangela Barbieri, Maria Rosaria Rizzo, Pasquale Paolisso, Giuseppe Paolisso, Raffaele Marfella

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Non-canonical lysosomal lipolysis drives mobilization of adipose tissue energy stores with fasting by GV Naveen Kumar, Rui-Sheng Wang, Ankit X. Sharma, Natalie L. David, Tânia Amorim, Daniel S. Sinden, Nandini K. Doshi, Martin Wabitsch, Sebastien Gingras, Asim Ejaz, J. Peter Rubin, Bradley A. Maron, Pouneh K. Fazeli, Matthew L. Steinhauser

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The Demographic Database — History of Technical and Methodological Achievements by Pär Vikström, Maria Larsson, Elisabeth Engberg, Sören Edvinsson

“… The Demographic Data Base (DDB) at the Centre for Demographic and Ageing Research (CEDAR) at Umeå University has since the 1970s been building longitudinal population databases and disseminating data for research. …”
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The Light and Shadow of Senescence and Inflammation in Cardiovascular Pathology and Regenerative Medicine by Laura Iop, Eleonora Dal Sasso, Leonardo Schirone, Maurizio Forte, Mariangela Peruzzi, Elena Cavarretta, Silvia Palmerio, Gino Gerosa, Sebastiano Sciarretta, Giacomo Frati

“…Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised tissue abilities to protect the heart against stress. …”
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A Chemically Defined Culture for Tooth Reconstitution by Ziwei Zhang, Hong Hu, Zhiheng Xu, Ce Shan, Hanyi Chen, Kun Xie, Kun Wang, Yifu Wang, Qing Zhu, Yike Yin, Haoyang Cai, Yunqiu Zhang, Zhonghan Li

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A study on the effect of nano-precipitates on fracture behavior of nano-structured Al-2wt%Cu alloy fabricated by accumulative roll bonding (ARB) process by Azad B., Borhani E.

“…The two kinds of different microstructures, i.e, solution treated (ST) one and 190°C pre-aged for 30 min (Aged), were prepared as the starting structures for the ARB process. …”
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Comparison of Geological Structures and Satellite-based Tectonic Lineaments in Gülağaç (Aksaray) and its Surroundings by Ramazan Demircioğlu

“…The basement of the study area consists of metamorphic rocks belonging to the Paleozoic–Mesozoic-aged Kaman Group. Mesozoic-aged ophiolites overlie these rocks, and both are cut by Late Cretaceous-aged igneous rocks. …”
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Does Routine Pain Assessment Result in Better Care? by Thomas Hadjistavropoulos, Ying C MacNab, Amanda Lints-Martindale, Ronald Martin, Heather Hadjistavropoulos

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Can Cognitive and Behavioural Disorders Differentiate Frontal Variant-Frontotemporal Dementia From Alzheimer’s Disease at Early Stages? by C. Jenner, G. Reali, M. Puopolo, M. C. Silveri

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Protecting cell cycle integrity: enhanced start-codon stringency in mitosis by Omid Omrani, Kanstantsin Siniuk, Martin Fischer

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A Deep Learning-Based Approach for Precise Emotion Recognition in Domestic Animals Using EfficientNetB5 Architecture by Rashadul Islam Sumon, Haider Ali, Salma Akter, Shah Muhammad Imtiyaj Uddin, Md Ariful Islam Mozumder, Hee-Cheol Kim

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Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease by Dmitri Leonoudakis, Anand Rane, Suzanne Angeli, Gordon J. Lithgow, Julie K. Andersen, Shankar J. Chinta

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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…The acute scarcity of critical care resources forced doctors in these countries to make allocation decisions at the bedside, which often resulted in de facto age-based allocation as well as experiences of moral distress and shame among providers.[4] In France, medical allocation guidelines and statistics were never released to the public, raising concerns over the role of transparency in implementing crisis standards and triage guidelines and causing the public to question the trustworthiness of provider triage.[5] Though many states in the US have crisis standards of care that can be implemented in the case of a large-scale triage event, these measures vary widely. …”
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Gestational Diabetes and Thyroid Autoimmunity by Ester Vitacolonna, Annunziata Lapolla, Barbara Di Nenno, Annalisa Passante, Ines Bucci, Cesidio Giuliani, Dominique Cerrone, Fabio Capani, Fabrizio Monaco, Giorgio Napolitano

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