Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases by Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Villegas, Jarosław Olav Horbanczuk, Ozlen Konu, Isabel Lastres-Becker, Anna-Liisa Levonen, Viktorija Maksimova, Charalambos Michaeloudes, Liliya V. Mihaylova, Michel Edwar Mickael, Irina Milisav, Biljana Miova, Patricia Rada, Marlene Santos, Miguel C. Seabra, Dubravka Svob Strac, Sandra Tenreiro, Ioannis P. Trougakos, Albena T. Dinkova-Kostova

“…Non-communicable chronic diseases (NCDs) are most commonly characterized by age-related loss of homeostasis and/or by cumulative exposures to environmental factors, which lead to low-grade sustained generation of reactive oxygen species (ROS), chronic inflammation and metabolic imbalance. …”
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Factors Contributing to Retention in Care and Treatment Adherence Among People Living With HIV Returning to Care in South-Eastern Tanzania: A Qualitative Study by Matimbwa H, Lolo SA, Matoy LS, Ndaki R, Ngahyoma S, Mollel HA, Luoga E, Vanobberghen F, Vianney JM, Idindili B, Weisser M

“…Data were analyzed by thematic analysis, with NVivo 12 software.Results: The median age of the 21 PLHIV was 40 years (range 21 to 63); 10 (47.6%) were females. …”
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Plasma IL-17A is increased in patients with critical MIS-C and associated to in-hospital mortality by Emmerson C. F. de Farias, Luciana M. P. P. do Nascimento, Manoel J. C. Pavão Junior, Dalila C. A. Pavão, Ana P. S. Pinheiro, Andreza H. O. Pinheiro, Marília C. B. Alves, Kíssila M. M. M. Ferraro, Larisse F. Q. Aires, Luana G. Dias, Mayara M. M. Machado, Michaelle J. D. Serrão, Raphaella R. Gomes, Sara M. P. de Moraes, Gabriela C. L. Pontes, Railana D. F. P. Carvalho, Cristiane T. C. Silva, Carla M. A. das Neves, Joyce C. L. dos Santos, Adriana M. B. de Sousa, Leda L. da Silva, Mary L. F. M. F. de Mello, Patricia B. Carvalho, Renata de B. Braga, Kathia de O. Harada, Maria C. A. Justino, Iran B. Costa, Igor Brasil-Costa, Marta C. Monteiro, Gleice Clemente, Maria Teresa Terreri

“…BackgroundMultisystem inflammatory syndrome in children (MIS-C) is a rare and severe post-COVID-19 complication with multiple phenotypes.ObjectivesThe aim of this study is to study inflammatory biomarkers (cytokines and oxidative stress) in critical MIS-C patients and to observe if there is association between these biomarkers and mortality.MethodsA single-center prospective study enrolled patients with MIS-C (with positive molecular test), aged between 1 month and 18 years of age. Data was collected from 20 pediatric intensive care unit (PICU)’s bed. …”
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Clinical and genetic drivers of oligo-metastatic disease in colon cancer by Alessandro Ottaiano, Mariachiara Santorsola, Roberto Sirica, Annabella Di Mauro, Antonella Di Carlo, Monica Ianniello, Francesco Sabbatino, Rosa Castiello, Francesca Del Peschio, Marco Cascella, Francesco Perri, Maurizio Capuozzo, Nicola Martucci, Edoardo Mercadante, Valentina Borzillo, Rossella Di Franco, Francesco Izzo, Vincenza Granata, Carmine Picone, Antonella Petrillo, Massimiliano Berretta, Salvatore Stilo, Luca Tarotto, Anna Chiara Carratù, Gerardo Ferrara, Madhura Tathode, Alessia Maria Cossu, Marco Bocchetti, Michele Caraglia, Guglielmo Nasti, Giovanni Savarese

“…Multivariate analysis adjusted for age (>70 vs. <70 years), gender (male vs. female), tumor side (right vs. left), metastatic involvement (more than one site vs. one site), response to first-line therapy (disease control vs. no disease control), and RAS/BRAF variants (wild-type vs. mutated) identified OMD vs. …”
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Long-term trends in the prevalence of cardiovascular-kidney-metabolic syndrome in South Korea, 2011–2021: a representative longitudinal serial studyResearch in context by Yesol Yim, Jae E. Lee, Yejun Son, Soeun Kim, Hojae Lee, Sooji Lee, Wonwoo Jang, Hanseul Cho, Hayeon Lee, Kyeongmin Lee, Hyesu Jo, Jaeyu Park, Jiyeon Oh, Louis Jacob, Jiseung Kang, Hyunji Sang, Sang Youl Rhee, Dong Keon Yon

“…Methods: This nationwide, cross-sectional study analyzed data from 61,106 Korean adults aged ≥20 years using the Korea National Health and Nutrition Examination Survey from 2011 to 2021. …”
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Association between plasma perfluoroalkyl substances and high-grade serous ovarian cancer overall survival: A nested case-control study by Wei-Yi Xing, Fang-Hua Liu, Dong-Dong Wang, Jia-Ming Liu, Wen-Rui Zheng, Jia-Xin Liu, Lang Wu, Yue-Yang Zhao, He-Li Xu, Yi-Zi Li, Yi-Fan Wei, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Qi-Peng Ma, Ting-Ting Gong, Qi-Jun Wu

“…Methods: We conducted a nested case-control study within the Ovarian Cancer Follow-Up Study, matching 159 dead patients and 159 survival ones based on body mass index, sample date, and age at diagnosis. Nine plasma PFASs were extracted by solid phase extraction and measured using a liquid chromatography system coupled with tandem mass spectrometry. …”
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Cohort profile: the multigeneration Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort by Thorarinn Gislason, Torben Sigsgaard, Vivi Schlünssen, Joachim Heinrich, Jesús Martínez-Moratalla, Øistein Svanes, Mathias Holm, Bertil Forsberg, Dan Norbäck, Rain Jogi, Kjell Torén, Deborah Jarvis, Magnus Ekström, Adrian Lowe, Caroline J Lodge, Michael Abramson, Shyamali Dharmage, Kathrine Pape, Cecilie Svanes, Gita Mishra, Caroline Lodge, Lyle Gurrin, Bruce Thompson, Eva Lindberg, Christer Janson, Simone Accordini, Ane Johannessen, Bryndis Benediktsdottir, Karl Franklin, Andrei Malinovschi, Anna Oudin, Francisco Gómez Real, José Luis Sánchez-Ramos, Lennart Bråbäck, Torgeir Storaas, Shanshan Xu, Julia Dratva, John Holloway, Jorunn Kirkeleit, Christine Cramer, Gro Tjalvin, Anne Mette Lund Würtz, Randi Jacobsen Bertelsen, Oskar Jõgi, Signe Timm, Francisco Javier Callejas, Raúl Godoy, Trude Duelien Skorge, Christine Drengenes, Nils Oskar Jõgi, Maryia Khomich, Toril Mørkve Knudsen, Ingrid Kuiper, Juan Pablo López-Cervantes, Marianne Lønnebotn, Shokouh Makvandi-Nejad, Antonio Pérez, Anders Røsland, Rajesh Shigdel, Svein Magne Skulstad, Kai Triebner, Hilde Vindenes, Jose Luis Sanchez, Jose Maldonado, David Martino, Jennifer Perret, Lucia Calciano, William Horsnell, Susanne Krauss-Etchmann

“…The RHINESSA core cohort, adult offspring generation 3 (G3), was first investigated in 2014–17 in a questionnaire study (N=8818, age 18–53 years) and a clinical study (subsample, n=1405). …”
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Optimizing Scanning in Youth Female Football: The Role of Verbal Instructions by Mirjam Hintermann, Michael Romann, Dennis Lüdin, Wolfgang Taube, Jörg Fuchslocher

“…Methods Twenty-five elite female football players (mean ± SD age : 17.6 ± 0.7 years) from two Swiss U19 women’s national league teams participated in this study. …”
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Prediction model for type 2 diabetes mellitus and its association with mortality using machine learning in three independent cohorts from South Korea, Japan, and the UK: a model de... by Hayeon Lee, Seung Ha Hwang, Seoyoung Park, Yunjeong Choi, Sooji Lee, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Soeun Kim, Jiyeon Oh, Lee Smith, Damiano Pizzol, Sang Youl Rhee, Hyunji Sang, Jinseok Lee, Dong Keon Yon

“…The SHAP value analysis of our proposed model revealed that age was the most important predictor of incident T2DM, followed by fasting blood glucose, hemoglobin, γ-glutamyl transferase level, and body mass index. …”
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Differences in dialysis modality choice between immigrant and native populations in Barcelona, Spain by María Dolores Arenas-Jiménez, Jose Luis Fernandez-Martin, Isabel Galcerán Herrera, Marisol Fernández-Chamarro, Guillermo Pedreira-Robles, Silvia Collado Nieto, Julia Farrera Núñez, Eva Rodríguez García, Alicia Moreno Rodríguez, Laura Morro Fernández, Marta Crespo Barrio, Julio Pascual Santos

“…However, after adjustment by age, this increased relative risk of mortality disappeared (HR 1.99[0.69–5.76], p = 0.206). …”
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600 meters to VO2max: Predicting Cardiorespiratory Fitness with an Uphill Run by Kübra Stoican, Regina Oeschger

“…In addition to the user’s anthropometric data (age, gender, body mass index) and time, we also used the speed to heart rate (HR) ratio as a predictor variable, since a previous study has shown its importance [8]. …”
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Recommendations for the use of natriuretic peptides for early diagnosis of heart disease in patients with diabetes: A consensus report by SPEDM, SPC, NEDM-SPMI and APMGF by João Sérgio Neves, Rui Baptista, Estêvão Azevedo de Pape, Manuel Rodrigues Pereira, Rita Paulos, Jonathan Pinheiro dos Santos, Cristina Gavina, João Jácome de Castro

“…Accordingly, this consensus advises the use of NT-proBNP analysis for all patients with diabetes aged 50 years and older, or under 50 if they have risk factors and/or comorbidities. …”
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Designing an educational model based on identity development with an Iranian-Islamic approach for primary school students. by Ali Oladhamzehzadeh, masoumeh oladiyan, Mahmoud Safari

“…The results showed that the grandparents of the ethnic minority from a young age and continued living during the multiracial participants have undertaken two focal processes in the process of racial and grandchild socialization of their grandchildren: as beacons of cultural socialization and single center goalkeepers. …”
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The Hubble Space Telescope Survey of M31 Satellite Galaxies. IV. Survey Overview and Lifetime Star Formation Histories by Alessandro Savino, Daniel R. Weisz, Andrew E. Dolphin, Meredith J. Durbin, Nitya Kallivayalil, Andrew Wetzel, Jay Anderson, Gurtina Besla, Michael Boylan-Kolchin, Thomas M. Brown, James S. Bullock, Andrew A. Cole, Michelle L. M. Collins, M. C. Cooper, Alis J. Deason, Aaron L. Dotter, Mark Fardal, Annette M. N. Ferguson, Tobias K. Fritz, Marla C. Geha, Karoline M. Gilbert, Puragra Guhathakurta, Rodrigo Ibata, Michael J. Irwin, Myoungwon Jeon, Evan N. Kirby, Geraint F. Lewis, Dougal Mackey, Steven R. Majewski, Nicolas Martin, Alan McConnachie, Ekta Patel, R. Michael Rich, Evan D. Skillman, Joshua D. Simon, Sangmo Tony Sohn, Erik J. Tollerud, Roeland P. van der Marel

“…From our SFHs, we find: (i) The median stellar age and quenching epoch of M31 satellites correlate with galaxy luminosity and galactocentric distance. …”
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Multimodal data-based longitudinal prognostic model for predicting atrial fibrillation recurrence after catheter ablation in patients with patent foramen ovale and paroxysmal atria... by Shoupeng Duan, Xujun Li, Jun Wang, Yuhong Wang, Tianyou Xu, Fuding Guo, Yijun Wang, Lingpeng Song, Zeyan Li, Xiaomeng Yang, Xiaoyu Shi, Hengyang Liu, Liping Zhou, Yueyi Wang, Hong Jiang, Lilei Yu

“…The constructed nomogram included four clinical variables: age, diabetes mellitus, lipoprotein (a), and right ventricular diameter. …”
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Identifying factors affecting the distribution strategy in the food industry with the attitude of marketing and online sales by solmaz seyedghafouri, Vahid nasehifar, Farid askari

“…They can pay attention to factors such as gender, age, geographical location, type of industry and other characteristics. …”
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IGJR 1/2020: Housing crisis: How can we improve the situation for young people? by IF and FRFG

“…At the same time, with pension systems under pressure because of ageing populations, the ownership of residential property has become an important component of old-age provision (Helbrecht/Geisenkauser 2012). …”
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IGJR 1/2020: Housing crisis: How can we improve the situation for young people? by IF and FRFG

“…At the same time, with pension systems under pressure because of ageing populations, the ownership of residential property has become an important component of old-age provision (Helbrecht/ Geisenkauser 2012). …”
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Designing a model for re-employment of employees during retirement (Study case: Ministry of Education) by Fatemeh Fatemeh Bina Baji, Hamid Rezaei Far, Mohammad Mohammadi, Monireh Salehnia

“…Considering the country's demographic changes and the effects and consequences of transitioning the age structure of the population, it is expected that the number of retirees in our society will continue to increase in the future decades (Statistical and Socioeconomic Analysis Office, 2019). …”
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Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial by Jeffry Nahmias, Daniel N Holena, Bellal Joseph, Martin Schreiber, Lisa M Kodadek, Mayur Narayan, Grace Chang, Joe Patton, Abid Khan, Mark Seamon, Jessica H Beard, Michelle T Bover Manderski, Michael A Vella, Ryan Peter Dumas, Haytham Kaafarani, Alison A Smith, Rachel Leah Choron, Christopher Bargoud, Amanda L Teichman, Francesk Mulita, Christine T Trankiem, Hashim Ahmed, Aaron Anderson, Odessa Pulido, Caleb Mentzer, Jane Keating, Mira Ghneim, Reynold Henry, Dane R Scantling, Andrew Benjamin, Christopher W Foote, Carlos H Palacio, Randi N Smith, Meghan Jonikas, Dias Argandykov, Jason D Sciarretta, Joshua P Hazelton, Pascal Udekwu, Jordan Michael Kirsch, Charoo Piplani, Julia Kuzinar, Dustin Hanos, Iman N Afif, Navpreet Kaur Dhillon, Ashling Zhang, Rebekah Devasahayam, Oliver Gunter, Brandi Sun, Chloe S Cao, Jessica K Reynolds, Lauren A Hilt, Karla Echeverria-Rosario, Nathaniel S Fung, Caitlin A Fitzgerald, Jeremy H Levin, JaeHee Yoon, Jacqueline Blank, Christopher J McLaughlin, Rami Al-Aref, Daniel S Howard, Kate Dellonte, Brent Hopkins, Chloe Shell, Evan G Wong, Howard Lieberman, Walter A Ramsey, Collin H Stewart, Claudia Alvarez, John D Berne, Ivan Puente, Ilya Rakitin, Lindsey Perea, Jason Wade, Laura K Mann, Vasileios Mousafeiris, Shari Reid-Gruner, Erica Sais, Lilamarie Moko

“…Included patients were ≥15 years of age with the American Association for the Surgery of Trauma grade IV–V duodenal and/or pancreatic injuries. …”
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