Outcome and prognostic value of N‐terminal pro‐brain natriuretic peptide and high‐sensitivity C‐reactive protein in mildly dilated cardiomyopathy vs. dilated cardiomyopathy by Jiayu Feng, Pengchao Tian, Lin Liang, Yuyi Chen, Yunhong Wang, Mei Zhai, Yan Huang, Qiong Zhou, Xuemei Zhao, Lang Zhao, Boping Huang, Liyan Huang, Yuhui Zhang, Jian Zhang

“…A total of 640 patients (median age 49 years, 24.8% female) were included in this study. …”
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Single-cell RNA sequencing highlights the role of distinct natural killer subsets in sporadic amyotrophic lateral sclerosis by Esther Álvarez-Sánchez, Álvaro Carbayo, Natalia Valle-Tamayo, Laia Muñoz, Joaquim Aumatell, Soraya Torres, Sara Rubio-Guerra, Jesús García-Castro, Judit Selma-González, Daniel Alcolea, Janina Turon-Sans, Alberto Lleó, Ignacio Illán-Gala, Juan Fortea, Ricard Rojas-García, Oriol Dols-Icardo

“…For this purpose, peripheral blood mononuclear cells (PBMC) were isolated from 14 ALS patients and 14 cognitively unimpaired healthy individuals (HC), matched by age and gender, and cryopreserved until library preparation and scRNAseq. …”
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Serum uric acid/creatinine ratio and 1-year stroke recurrence in patient with acute ischemic stroke and abnormal renal function: results from the Xi'an stroke registry study of Chi... by Zhongzhong Liu, Zhongzhong Liu, Zhongzhong Liu, Dandan Zhang, Dandan Zhang, Lingxia Zeng, Weiyan Guo, Qingli Lu, Qingli Lu, Zhen Lei, Yunlong Hao, Pei Liu, Pei Liu, Tong Liu, Tong Liu, Linna Peng, Linna Peng, Qiaoqiao Chang, Qiaoqiao Chang, Mi Zhang, Mi Zhang, Xuemei Lin, Xuemei Lin, Fang Wang, Fang Wang, Songdi Wu, Songdi Wu, Songdi Wu, Songdi Wu

“…Multivariable Cox regression, curve fitting, and stratified analyses were employed to assess the relationship between SUA/SCr and 1-year stroke recurrence in patients with AIS and abnormal renal function, considering SUA/SCr as both a continuous variable and in quartiles (Q1–Q4).ResultsOf 1,932 enrolled patients (65.3% male; mean age 66.7 ± 11.3 years), each unit of increase in SUA/SCr was associated with a 17% decrease in 1-year stroke recurrence (HR = 0.83, 95% CI 0.73 to 0.96, P = 0.009). …”
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A prospective observational cohort study of HIV infection in Indonesia: baseline characteristics and one-year mortality by Tuti P. Merati, Evy Yunihastuti, Rudi Wisaksana, Nia Kurniati, Dona Arlinda, Muhammad Karyana, Nugroho H. Susanto, Dewi Lokida, Herman Kosasih, Aly Diana, Lois E. Bang, Melinda Setiyaningrum, Desrinawati M. Amin, Eppy Eppy, Wiwit A. S. N. Cahyawati, Emon W. Danudirgo, I Made Gede Darmaja, Nur Farhanah, Carta A. Gunawan, Usman Hadi, Kurnia F. Jamil, Sudirman Katu, Tambar Kembaren, I Gede Rai Kosa, Danang L. Norosingomurti, Asep Purnama, Ida S. Laksanawati, Adria Rusli, I Ketut Agus Somia, Yanri W. Subronto, Ivan L. Toruan, Renee Ridzon, C. Jason Liang, Aaron T. Neal, Ray Y. Chen, INA-PROACTIVE Study Group

“…Other factors at enrollment significantly associated with mortality were a CD4 + count < 200 (aHR 8.02, 95% CI: 2.69–23.86; compared to ≥ 350), age 40–49 years (aHR 2.19, 95% CI 1.23–3.87; compared to 18–29 years) and being underweight (aHR 1.84, 95% CI: 1.18–2.85; compared to normal weight). …”
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Editorial by Pieter Vanhuysse, Antony Mason, Jörg Tremmel, Markus Rutsche, Maria Lenk

“… Population ageing across the advanced economies (though not in large parts of Africa and Asia) has become a growing concern for academics, policy-makers and the public at large. …”
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Experiencia en DAC cardiaca en la Comunidad Valenciana: programa de extracción cardiaca extrahospitalaria by Audelio Guevara-Bonilla, Eduardo Tébar-Botí, Claudia Aguirre-Ramón, Alexandra Merino-Orozco, Carlos Domínguez-Massa, Manuel Pérez-Guillén, Ana Bel-Mínguez, Salvador Torregrosa-Puerta, Tomás Heredia-Cambra, Alejandro Rincón-Almanza, María J. Dalmau-Sorli, Iván Martín González, Francisco J. Valera Martínez, Ana Tur-Alonso, Juan B. Martínez León

“…Results: Of the 21 possible donors, 19 were valid hearts, 2 of them were for a hospital outside the community. The mean age of the donors was 40.4 years, most of them men. …”
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Establishment and evaluation of nomogram model for risk of PICC related upper extremity deep vein thrombosis in elderly patients (高龄患者PICC导管相关性上肢深静脉血栓发生风险的列线图模型构建与评估)... by YAN Ying (闫影), QI Xiaojiu (齐晓玖), SU Qian (苏倩), WANG Pei (王培)

“…The results of Logistic regression model showed that the age, malignant tumor, D-D level before catheterization and operation history during catheterization were independent risk factors for upper extremity DVT in elderly patients with PICC (P<0. 05); The risk factors affecting the occurrence of PICC related upper extremity DVT in elderly patients were introduced into R software (R3. 6. 3) rms package to establish nomogram prediction model, the area under the ROC curve was 0. 777, the slope of calibration curve was close to 1, and the Hosmer-Lemeshow goodness-of-fit test showed χ2=9. 637, P=0. 291. …”
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Geriatric nutritional risk index and newly developed scoring system as prognosis prediction for unresectable hepatocellular carcinoma patients treated with lenvatinib by Hideko Ohama, Atsushi Hiraoka, Toshifumi Tada, Masashi Hirooka, Kazuya Kariyama, Joji Tani, Masanori Atsukawa, Koichi Takaguchi, Ei Itobayashi, Shinya Fukunishi, Kunihiko Tsuji, Toru Ishikawa, Kazuto Tajiri, Hironori Ochi, Satoshi Yasuda, Hidenori Toyoda, Chikara Ogawa, Takashi Nishimura, Takeshi Hatanaka, Satoru Kakizaki, Noritomo Shimada, Kazuhito Kawata, Atsushi Naganuma, Hisashi Kosaka, Tomomitsu Matono, Hidekatsu Kuroda, Yutaka Yata, Hironori Tanaka, Hiroki Nishikawa, Hiroshi Shibata, Fujimasa Tada, Kazuhiro Nouso, Asahiro Morishita, Akemi Tsutsui, Takuya Nagano, Norio Itokawa, Tomomi Okubo, Taeang Arai, Michitaka Imai, Yohei Koizumi, Shinichiro Nakamura, Hiroko Iijima, Masaki Kaibori, Yoichi Hiasa, Takashi Kumada

“…From 2018 to 2022, 484 uHCC patients treated with LEN (384 males, median age 73). Prognostic value was compared between GNRI and C-reactive protein (CRP) scoring (GNRI-C score), GNRI, and neo-Glasgow prognostic score (neo-GPS). …”
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Outcomes and risk factors of transported patients with extracorporeal membrane oxygenation: An ECMO center experience by Lingjuan Liu, Dingji Hu, Tong Hao, Shanshan Chen, Lei Chen, Yike Zhu, Chenhui Jin, Jing Wu, Haoya Fu, Haibo Qiu, Yi Yang, Songqiao Liu

“…Result: Out of 303 patients supported with ECMO, 111 (36.6%) were transported. 69.4% of the transport group were male, mean age was (42.0±17.0) years, mean body mass index was (24.4±4.6) kg/m2, and veno-arterial-ECMO accounted for 52.5%. …”
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Le mobilier en cuir antique et médiéval du boulevard Dr Henri-Henrot à Reims/Durocortorum by Martine Leguilloux

“…The second group is that of the quartered upper portions, which are found in all levels until the early Middle Ages (state 13). For each group, high topped models exist, rising to the ankle, and others with lower upper portions. …”
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Association of chronic heart failure with mortality in old intensive care patients suffering from Covid‐19 by Raphael Romano Bruno, Bernhard Wernly, Georg Wolff, Jesper Fjølner, Antonio Artigas, Bernardo Bollen Pinto, Joerg C. Schefold, Detlef Kindgen‐Milles, Philipp Heinrich Baldia, Malte Kelm, Michael Beil, Sigal Sviri, Peter Vernon vanHeerden, Wojciech Szczeklik, Arzu Topeli, Muhammed Elhadi, Michael Joannidis, Sandra Oeyen, Eumorfia Kondili, Brian Marsh, Finn H. Andersen, Rui Moreno, Susannah Leaver, Ariane Boumendil, Dylan W. De Lange, Bertrand Guidet, Hans Flaatten, Christian Jung, COVIP study group

“…After multivariate adjustment for confounders (SOFA, age, sex, and frailty), no independent association of CHF with mortality remained [adjusted odds ratio (aOR) 1.2, 95% CI 0.5–1.5; P = 0.137]. …”
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De l’agglomération antique de Cassinomagus au village de Chassenon (Charente) : un bilan des connaissances by Lucie Carpentier, Sandra Sicard

“…Excavations carried out in the eastern part of the site revealed traces of occupation dating back to the Second Iron Age, though it remains impossible to determine whether these vestiges correspond to the origins of the urban concentration that would become Cassinomagus, or whether they are merely indicative of the presence of marginal rural occupation at that time. …”
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Territorios rurales en transformación: desafíos y oportunidades frente al reto de la despoblación by Néstor Vercher

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Effects of non-pharmacological interventions on depressive and anxiety symptoms in pregnant women: a systematic review and network meta-analysisResearch in context by Guowei Zeng, Jianfeng Niu, Ke Zhu, Fei Li, Liwen Li, Kaiming Gao, Yanlong Zhuang, Boyang Zhang, Xiaoqiang Han, Gang Ye, Zhikun Gao, Haobai Li

“…The outcomes were assessed in two groups of participants: a high-risk pregnancy group, including pregnant women with depressive and/or anxiety symptoms and high-risk pregnancies (defined as having a history of miscarriage, pregnancy complications such as gestational hypertension, gestational diabetes mellitus, or preeclampsia, and advanced maternal age (i.e., over 35 years old); and a healthy group, including participants who exhibited depressive and/or anxiety symptoms only during pregnancy and did not have other high-risk pregnancy conditions or underlying health issues. …”
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Comparative Effectiveness of Rosuvastatin Versus Atorvastatin in Acute Ischemic Stroke Treatment by Joon‐Tae Kim, Ji Sung Lee, Hyunsoo Kim, Beom Joon Kim, Jihoon Kang, Keon‐Joo Lee, Jong‐Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae‐Kwan Cha, Dae‐Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun‐Sik Hong, Yong‐Jin Cho, Hong‐Kyun Park, Byung‐Chul Lee, Kyung‐Ho Yu, Mi Sun Oh, Dong‐Eog Kim, Jay Chol Choi, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong‐Ho Hong, Sang‐Hwa Lee, Man‐Seok Park, Wi‐Sun Ryu, Kwang‐Yeol Park, Juneyoung Lee, Jeffrey L. Saver, Hee‐Joon Bae

“…Results A total of 43 512 patients (age, 69.2±12.5 years; male, 59.8%) were analyzed in this study. …”
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Editorial by Michael Rose, Jonathan M. Hoffmann

“…The girl was about to decide whether or not to conceive a child at her age, and Parfit argued that she would not make that particular child worse off by conceiving now (although giving him a bad start in life) as opposed to waiting a few years and heaving a child as a grown-up. …”
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Triglyceride-glucose-body mass index and the incidence of cardiovascular diseases: a meta-analysis of cohort studies by Xiyun Rao, Ziyi Xin, Qingwen Yu, Lanlan Feng, Yongmin Shi, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Jiake Tang, Xingwei Zhang, Mingwei Wang, Ling Liu

“…The results indicated that Compared with the lowest TyG-BMI index category, the highest TyG-BMI index was related to a higher incidence of cardiovascular diseases (CVD) (HR = 1.62; 95% confidence interval (CI): 1.35–1.95; I2 = 94%),coronary artery disease (CAD) (HR = 1.69; 95% (CI): 1.23–2.31; I2 = 94%). stroke(HR = 1.57; 95% (CI): 1.11–2.23; I2 = 94%).In the dose–response analysis, there was a linear association of the TyG-BMI index with the risk of CVD (Pnonlinear = 0.223), CAD (Pnonlinear = 0.693), and stroke (Pnonlinear = 0.122)No significant effects were observed regarding participants’ gender, length of follow-up, sample size or mean age(P > 0.05). Conclusion Higher TyG-BMI may be independently associated with an increased risk of CVD in individuals without CVD at baseline. …”
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Serum NFL and neuropsychological performance over ∼8 years in women with and without HIV: a longitudinal repeated measures studyResearch in context by Deborah R. Gustafson, Xuantao Li, Alison E. Baird, Henrik Zetterberg, Kaj Blennow, Jinbing Zhang, Amanda Blair Spence, Pauline Maki, Anjali Sharma, Kathleen Weber, Recai Yucel

“…Methods: We assessed cross-sectional and longitudinal change in sNFL between 2008 and 2019 associated with neuropsychological performance (NP) among women living with HIV (WLWH) and without HIV (WLWOH) age ≥40 years in the Women's Interagency HIV Study. …”
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Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group by Aysegul Oruc, Abdullah Sumnu, Aydın Turkmen, Taner Basturk, Egemen Cebeci, Kenan Turgutalp, Hakkı Cetinkaya, Müge Uzerk Kibar, Nurhan Seyahi, Erhan Tatar, Metin Ergul, Ülver Derici, Mehmet Deniz Aylı, Musa Pınar, Betül Bakar, Rümeyza Kazancıoglu, Abdülmecit Yıldız, Ahmet Burak Dirim, Zülfükar Yılmaz, Kültigin Turkmen, Onur Tunca, Mehmet Koc, Sim Kutlay, Hasan Micozkadıoglu, Alper Azak, Burcu Boztepe, Sedat Ustundag, Seda Şafak Ozturk, Abdulkadir Unsal, Serhat Karadag, Gülizar Sahin, Ezgi Coşgun Yenigun, Necmi Eren, Mustafa Gullulu, Meltem Gursu, Savaş Ozturk

“…A total of 408 primary IgAN patients treated with IST (65.4% male, mean age 38.4 ± 12.5 years, follow-up 30 (3–218) months) were included and divided into two groups according to treatment protocols (isolated corticosteroid [CS] 70.6% and combined IST 29.4%). …”
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Perioperative tislelizumab plus chemotherapy for locally advanced gastroesophageal junction adenocarcinoma (NEOSUMMIT-03): a prospective, nonrandomized, open-label, phase 2 trial by Run-Cong Nie, Shu-Qiang Yuan, Ya Ding, Yong-Ming Chen, Yuan-Fang Li, Cheng-Cai Liang, Mu-Yan Cai, Guo-Ming Chen, Wei Wang, Xiao-Wei Sun, De-Sheng Weng, Dan-Dan Li, Jing-Jing Zhao, Xiao-Jiang Chen, Yuan-Xiang Guan, Zhi-Min Liu, Yao Liang, Ma Luo, Jun Chi, Hai-Bo Qiu, Zhi-Wei Zhou, Xiao-Shi Zhang, Ying-Bo Chen

“…Thirty-two patients were enrolled. The median age was 60 years (range: 28–74 years), and 53.1% (17/32) patients were Siewert III type. …”
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