Structure of Patients with Hepatocellular Cancer (Data Analysis from Two Specialised Centres) by M. V. Mayevskaya, M. S. Novruzbekov, I. M. Borovkov, D. G. Trofimova, M. S. Zharkova, V. D. Lunkov, K. N. Lutsyk, O. D. Olisov

“…In the analysis of HCC patients, the ratio of men to women was 3:1 (64 men and 22 women), the median age was 54.5 years (IQR 48–59). The median time from the establishment of chronic liver disease to the detection of HCC was 7.5 years (IQR 3–14.5). …”
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Improving Anxiety Related to Chronic Pain Through a Sleep Circadian Intervention Program: A Pilot Study by Sonia López-Monzoni, Gloria Hernando Benito, Sofía Romero-Peralta, Laura Silgado-Martínez, Maria Esther Viejo-Ayuso, Leticia Álvarez-Balado, Enrique Rodríguez Matarranz, Carles Forné Izquierdo, Manuel Sánchez-de-la-Torre, Juan Fernando Masa, Ferrán Barbé, Francisco García-Río, Antonio Martínez-Nicolás, Belén García-Mediano, Esther Solano-Pérez, Olga Mediano

“…This was a randomized clinical trial (NCT03646084), in which 49 CMP patients were assigned to SCIP (<i>n</i> = 15, mean age 51 years and 40% women) or non-SCIP groups (<i>n</i> = 26, 53 years and 61.5% women). …”
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Early initiation of intravenous cyclophosphamide and one‐year outcome in super‐refractory cryptogenic‐new onset refractory status epilepticus by Yasufumi Yorichika, Shuichiro Neshige, Hideaki Sakahara, Narumi Ono, Megumi Nonaka, Yuichiro Tagane, Tomoaki Watanabe, Keisuke Tachiyama, Haruka Ishibashi, Masahiro Nakamori, Takeo Shishido, Shiro Aoki, Hiroki Ueno, Yu Yamazaki, Takahiro Iizuka, Hirofumi Maruyama

“…We compared functional outcomes at 3 months and 1 year after the onset between patients who received IVCPA within 20 days (early‐treated) and those who received it later (late‐treated). All patients (median age: 43 years) had a prodromal fever. Brain MRI revealed symmetrically increased FLAIR signals in the medial temporal lobes of all patients. …”
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First-year dynamics of the anaerobic microbiome and archaeome in infants’ oral and gastrointestinal systems by Charlotte J. Neumann, Rokhsareh Mohammadzadeh, Pei Yee Woh, Tanja Kobal, Manuela-Raluca Pausan, Tejus Shinde, Victoria Haid, Polona Mertelj, Eva-Christine Weiss, Vassiliki Kolovetsiou-Kreiner, Alexander Mahnert, Christina Kumpitsch, Evelyn Jantscher-Krenn, Christine Moissl-Eichinger

“…Additionally, we found that archaeal signatures are present in infants under 1 year of age, but they do not form a stable archaeome. In contrast to this, we could track specific bacterial strains transitioning from oral to gut or persisting in the gut over time.…”
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Renewal of wheat cultivars enhances ozone resistance in yield but detrimentally impacts quality: a survey of Chinese wheat by Yinsen Qian, Zheng Zhao, Yifan Cao, Quan Ma, Nanyan Zhu, Lingqi Song, Min Zhu, Min Zhu, Chunyan Li, Chunyan Li, Jinfeng Ding, Jinfeng Ding, Wenshan Guo, Wenshan Guo, Xinkai Zhu, Xinkai Zhu, Xinkai Zhu

“…Despite extensive research on the impacts of O3 on wheat production and the ongoing development of new wheat cultivars over the years, a connection between yield loss and the released ages of wheat cultivars under O3 stress remains unestablished. …”
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Mortality Risk Prediction in Patients With Antimelanoma Differentiation–Associated, Gene 5 Antibody–Positive, Dermatomyositis–Associated Interstitial Lung Disease: Algorithm Develo... by Hui Li, Ruyi Zou, Hongxia Xin, Ping He, Bin Xi, Yaqiong Tian, Qi Zhao, Xin Yan, Xiaohua Qiu, Yujuan Gao, Yin Liu, Min Cao, Bi Chen, Qian Han, Juan Chen, Guochun Wang, Hourong Cai

“…ML identified 8 important variables as critical for model construction: RP-ILD, erythrocyte sedimentation rate (ESR), serum albumin (ALB) level, age, C-reactive protein (CRP) level, aspartate aminotransferase (AST) level, lactate dehydrogenase (LDH) level, and the neutrophil-to-lymphocyte ratio (NLR). …”
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The expression of MALAT1, plasma brain natriuretic peptide, and Tei index in sepsis-induced myocardial injury by Guangqing Huang, Wenzi Yang, Xu Zhao, Yong Bai, Xing Jiang, Jie Liu

“…Results In terms of general information, there were no significant differences in gender, age, BMI, mean arterial pressure, systolic pressure, diastolic pressure, respiratory rate, oxygenation index, basic diseases and infection site between the two groups (P > 0.05). …”
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<em>Giardia duodenalis</em> en Algérie : une revue dans le cadre du concept Une seule santé by Myriam Thomas, Bruno Polack, Mohamed Mammeri

“…La prévalence et la diversité génétique des isolats de G. duodenalis variaient selon les régions et les groupes d’âge, aussi bien chez les humains que chez les animaux. …”
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Relationship between pharmacotherapy for major depressive disorder and healthcare utilisation in British Columbia, Canada: a retrospective population-based cohort by Sonya Cressman, Louisa Edwards, Kimberlyn McGrail, Stirling Bryan, Alison Hoens, Rohit Vijh, Sandra Peterson, Zeina Waheed, Mary Bunka, Nick Pang, Shahzad Ghanbarian, Gavin Wong, Linda Riches, Jehannine Austin

“…Objectives To describe the population that meets the criteria for major depressive disorder (MDD) in British Columbia (BC), compare patterns of healthcare utilisation between those with MDD who are and are not prescribed pharmacotherapy, and assess these relationships in models that control for potential confounding variables.Design We used a population cross-sectional study design among a cohort of individuals living with MDD and examined the relationship between pharmacotherapy and healthcare utilisation between 2019 and 2020 using linked billing and administrative data.Setting This study identified individuals with MDD using a validated case definition of International Classification of Diseases (ICD) codes in BC, Canada.Participants The final study cohort included 549 029 adult participants who met the MDD case definition.Explanatory variable Explanatory variable was the use of prescription antidepressant medication during the study period, based on BC PharmaNet data.Covariates Covariates include sociodemographic characteristics (age, sex, urban/rural residence, neighbourhood income quintile and comorbidities).Primary outcome measure Primary outcome measure was healthcare utilisation (outpatient physician visits, emergency department (ED) visits and hospitalisations).Results We stratified our analysis based on whether study participants were classified as ‘recently incident’ or ‘actively prevalent’. …”
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The Use of Biopsy and “No-Biopsy” Approach for Diagnosing Paediatric Coeliac Disease in the Central European Region by Petra Riznik, Márta Balogh, Piroska Bódi, Luigina De Leo, Jasmina Dolinsek, Ildikó Guthy, Judit Gyimesi, Ágnes Horváth, Ildikó Kis, Martina Klemenak, Berthold Koletzko, Sibylle Koletzko, Ilma Rita Korponay-Szabó, Tomaz Krencnik, Tarcisio Not, Goran Palcevski, Éva Pollák, Daniele Sblattero, István Tokodi, Matej Vogrincic, Katharina Julia Werkstetter, Jernej Dolinsek

“…Data from 653 children (63.9% female, median age: 7 years, range: 7 months-18.5 years) from Croatia, Hungary, Germany, Italy, and Slovenia were analysed. …”
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Gut health-promoting foods intake in Argentine adults: The impact of knowledge, socio-demographic factors, and clinical-nutritional health by Georgina Noel Marchiori, Mayra Ainelén Loyola, Clara Marián Levy Sánchez, María Daniela Defagó, María Georgina Oberto

“…Methods: A cross-sectional study was conducted on 2128 Argentine adults aged 18-82 years-old. An online questionnaire was used to collect socio-demographic, clinical-nutrition and dietary data, as well as information about population's knowledge. …”
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Diabetes distress among immigrants of south Asian descent living in New York City: baseline results from the DREAM randomized control trial by Farhan Mohsin, Laura Wyatt, Hayley Belli, Shahmir Ali, Deborah Onakomaiya, Supriya Misra, Yousra Yusuf, Shinu Mammen, Jennifer Zanowiak, Sarah Hussain, Haroon Zafar, Sahnah Lim, Nadia Islam, Naheed Ahmed

“…Results Overall, 414 participants completed the DDS at baseline (median age = 55.2 years; SD = 9.8). All were born outside of the US; the majority were born in Bangladesh (69.8%) followed by India, Pakistan, and Nepal (24.7%) and Guyana and Trinidad and Tobago (5.5%). …”
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Long-term effectiveness of radiofrequency renal denervation in patients with resistant arterial hypertension (10-year follow-up results) by O.L. Rekovets, Yu.M. Sirenko, O.O. Torbas, S.M. Kushnir, G.F. Prymak

“…RDN was performed in 8 patients (0.70 %). 8 patients refused the procedure. The age was 52.13 ± 3.88 years (40–66), the duration of hypertension was 16.75 ± 2.17 (12–25) years. …”
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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…Schoolchildren (n = 183) between the ages of 6 and 12 years living in southern Taiwan were recruited to measure their serum inflammation including interferon-γ (IFN-γ), IFN-α2, interleukin 1b (IL-1b), IL-2, IL-6, IL-10, IL-13, IL-17, monocyte chemotactic protein (MCP)-l, and tumor necrosis factor (TNF-α). …”
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Effects of Mixing Tree Species on Soil Enzyme Activity and Carbon-Use Efficiency in Eroded Masson Pine Forest by WANG Man, JIANG Yongmeng, ZHANG Shiliang, ZHANG Jinxiu, ZHENG Linmin, ZENG Zhiwei, LYU Maokui, XIE Jinsheng

“…[Results] (1) With the increase of restoration years, soil acid phosphatase (AP) and β-glucosidase (βG) activities were significantly reduced, while C∶NEEA (βG∶NAG), vector length (VL) and vector angle (VA) of the mixed forest were lower than that of pure forest, while C∶PEEA (βG∶AP) and N∶PEEA (NAG∶AP) showed the opposite trend, indicating that long-term mixing is beneficial to alleviate the carbon limitation and phosphorus limitation of microorganisms. (2) Mixing was beneficial to improve CUE and significantly increased with the increase of forest age. Specifically, compared with that of Y39-CF and Y19-MF, CUE of Y39-MF significantly increased by 200.00% and 136.84%, respectively. (3) By analyzing the characteristics of soil enzyme activity and the relationship between CUE and environmental factors, it was found that soil carbon, nitrogen and phosphorus availability was an important influencing factor, mainly affecting AP activity, C∶PEEA, N∶PEEA, VL, VA and CUE, while the stoichiometric ratio of soil nutrients mainly affected βG activity and C∶NEEA. (4) The results of redundancy analysis (RDA) showed that the ratio of fungi and bacteria mainly affected the characteristics of soil enzyme activity and CUE in the mixed forest, while the main influencing factors in pure forest were actinomyces and Gram-negative bacteria. …”
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Real-world clinical outcome of unresectable locally advanced & de-novo metastatic pancreatic ductal adenocarcinoma: a multicentre retrospective study by Mohamed Aseafan, Ali H. Alfakeeh, Emad Tashkandi, Mervat Mahrous, Mohammed Alghamdi, Bader Alshamsan, Marwan Al-Hajeili, Safwan Bakhsh, Kanan Alshammari, Fahad A. Almugbel, Abdulhameed H. Alfagih, Ahmed Allehebi, Mohamed Montaser, Mohamed Hamdy Elsafty, Khaled Abd Elaziz Elnaghi, Ibrahim Issa, Eesa Bakshi, Sadeem AlSubaie, Bandar AlMutairi, Hoda Mokhtar, Mohamed Aboelatta, Nedal Bukhari, Ali M. Alzahrani, Tusneem Elhassan, Ali Alqahtani, Shouki Bazarbashi

“…Data were collected from 10 oncology centers across Saudi Arabia. Results The median age at diagnosis was 60 years, with 63% of patients presenting with multiple metastatic sites, primarily in the liver (66.3%). …”
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Senile cataract — features of development and outcomes of surgical treatment in patients with hepatitis B and C viruses by B.N. Hatsukova, G.M. Chernakova, S.A. Kochergin, E.A. Kleshcheva, E.Yu. Malinnikova, K.K. Kyuregyan, M.M. Mikhailov

“…<br> <b>Results</b>: average age of patients in the main group was 61.9±5.23 years, in the control group — 69.4±3.12. …”
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Administration of Sex Hormone Preparations as a Risk Factor in the Development of Intrahepatic Cholestasis of Pregnancy and Biliary Sludge in Pregnant Women by Yu. B. Uspenskaya, I. V. Kuznetsova, A. A. Sheptulin, N. V. Goncharenko, A. N. Gerasimov, M. M. Amiraslanova

“…Prognostic factors in the insufficient effectiveness of BS treatment: the use of sex hormone preparations during pregnancy, the presence of the polycystic ovary syndrome (PCOS) in the anamnesis, an older age at the time of pregnancy and conception after ART.Conclusion. …”
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Role of Intravitreal Antivascular Endothelial Growth Factor Injections for Choroidal Neovascularization due to Choroidal Osteoma by Ahmad M. Mansour, J. Fernando Arevalo, Eman Al Kahtani, Hernando Zegarra, Emad Abboud, Rajiv Anand, Hamid Ahmadieh, Robert A. Sisk, Salman Mirza, Samuray Tuncer, Amparo Navea Tejerina, Jorge Mataix, Francisco J. Ascaso, Jose S. Pulido, Rainer Guthoff, Winfried Goebel, Young Jung Roh, Alay S. Banker, Ronald C. Gentile, Isabel Alonso Martinez, Rodney Morris, Neeraj Panday, Park Jung Min, Emilie Mercé, Timothy Y. Y. Lai, Vicky Massoud, Nicola G. Ghazi

“…We treated 26 eyes of 25 young patients having a mean age of 30 years with intravitreal vascular endothelial growth factor (VEGF) inhibitor for choroidal new vessel (CNV) formation overlying choroidal osteoma over a mean follow-up of 26 months. …”
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Nucleotide variation in Foxp3 gene and prognosis of bladder cancer: a case-control study by Qin Li, Yan Zhang, Yan Zhang, Min Su, Yaping Song, Yanyun Wang, Bin Zhou, Lin Zhang

“…Notably, individuals who were homozygous for the AA genotype demonstrated a markedly lower overall survival (OS) rate compared to those with the CC/CA genotypes (P = 0.03, OR = 5.89, 95%CI = 1.23-28.15), after adjusting for factors such as age, gender, smoking status, tumor grade, metastasis, and clinical stage. …”
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