Intraocular inflammation after intravitreal injection of aflibercept 8 mg for treatment-refractory neovascular age-related macular degeneration: a case report by Nozomu Hashiya, Ichiro Maruko, Yuri Miyaguchi, Ruka Maruko, Taiji Hasegawa, Tomohiro Iida

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Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study by Giorgio Bedogni, Roberto Berni Canani, Laura Carucci, Rita Nocerino, Serena Coppola, Pasqualina Capasso, Veronica Giglio

“…Anamnestic and clinical data were collected from all enrolled patients.Results 123 non-IgE-GIFA patients were enrolled (56% male, median age (IQR) 150 (60–300) days): FPE (39%), FPIES (17%), FPIAP (16%) and FPIMD (28%). 42% of patients had multiple food allergies (FAs) at baseline, and 64% had a positive family history of allergy. …”
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Temporal trends and cohort variations of gender-specific major depressive disorders incidence in China: analysis based on the age-period-cohort-interaction model by Chao Guo, Xiyuan Hu

“…Background Major depressive disorders (MDDs) impose substantial burdens on individuals and society; however, further detailed analysis is still needed for its long-term trends.Aims This study aimed to analyse the gender-specific temporal trends and cohort variations of MDD incidence among Chinese residents over the past three decades.Methods Employing the age-period-cohort-interaction model and leveraging data from the Global Burden of Disease Study 2019, this research identified and analysed incidence trends of MDD among Chinese males and females aged 5–94 years from 1990 to 2019 across three dimensions, encompassing age, period and birth cohort.Results The analysis reveals age-related effects, indicating heightened MDD risk among adolescents and older adults. …”
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Growth Performance, Body Measurements and Live Weight Estimation of Tülü (Bactrian × Dromedary F1) Calves from Birth to Six Months of Age by Atakan Koç, Alkan Çağlı

“…Tülü calves average birth weight (BW) was 34.7±1.80 kg and reached 175.3±3.38 kg at the age of 6 months with a 0.768±0.03 kg DWG during this time. …”
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Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury by Susan Bengs, Alexia Rossi, Martina Haberecker, Nidaa Mikail, Alexander Meisel, Achi Haider, Muriel Grämer, Angela Portmann, Atanas Todorov, Christof Schönenberger, Caroline E. Gebhard, Gabriela M. Kuster, Vera Regitz-Zagrosek, Catherine Gebhard

“…We sought to analyze the impact of sex hormones, age, and cardiovascular disease on ACE-2 and TMPRSS-2 expression in different mouse models. …”
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Real-Life State of Anti-Hepatitis B Virus Drug Choice in Child-Bearing Age Male Patients and Effect on Fertility and Fetal Safety by Zhao X. Hu, Yi N. Ye, Wei G. Wu, Xu J. Liang, Qi W. Wu, Ao Zhang, Xing R. Zheng, Zhi L. Gao, Liang Peng, Chan Xie

“…Based on whether they received antiviral therapy during conception or not, we divided patients into two groups. In the child-bearing age group, 88.33% (106/120) of patients received telbivudine (LDT), whereas the other group mainly received entecavir (ETV) (87.20%, 586/672). …”
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The Association Between the Onset and Ending of Volunteering on Loneliness and Perceived Social Isolation Among Older Adults: Longitudinal Evidence From the German Ageing Survey by Avery Richardson, Hans‐Helmut König, André Hajek

“…Methods Longitudinal data were obtained from Waves 5 (Year 2014) and 6 (Year 2017) of the German Ageing Survey, focusing on middle‐aged and older adults. …”
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The 4E theory-based performance benchmarking of aged care service provision in community care facilities: a case study of Nanjing, China by Wei Huang, Wei Huang, Ying Hu, Lingzhi Li, Chendi Wang, Luyao Liu

“…The global aging population is growing rapidly, and due to its large population, China is expected to become a ‘super-aged society’ within the next decade. …”
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Le cimetière de la fin du Premier Moyen Âge de Virelles (Chimay, Belgique) : pratiques funéraires et profils biologiques by Eugenie Picot, Caroline Laforest, Nicolas Authom, Frederic Chantinne, Dominique Castex

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Antimicrobial Susceptibility Patterns of Shigella Species among Children under Five Years of Age with Diarrhea in Selected Health Centers, Addis Ababa, Ethiopia by Basha Ayele, Zeleke Mekonnen, Tesfaye Sisay Tessema, Etsehiwot Adamu, Estifanos Tsige, Getenet Beyene

“…This study aimed to characterize the antimicrobial features of the Shigella species isolated from children under five years of age with acute diarrhea in Addis Ababa, Ethiopia. …”
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Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men by Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, Kazuo Tsubota, Kaori Hayashi, Jun Yoshino, Hiroshi Itoh

“…Obesity and aging are major risk factors for several life-threatening diseases. …”
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Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs) by Jeffrey J. Yu, Daniel B. Azzam, Marilyn Chwa, Kevin Schneider, Jang-Hyeon Cho, Chinhui Hsiang, Henry Klassen, M. Cristina Kenney, Jing Yang

“…One of the leading causes of irreversible blindness worldwide, age-related macular degeneration (AMD) is a progressive disorder leading to retinal degeneration. …”
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Les réseaux transsahariens de la traite de l’or et des esclaves au haut Moyen Âge : VIIIe-XIe siècle by Roger Botte

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Age-Dependent Switch of the Role of Serotonergic 5-HT1A Receptors in Gating Long-Term Potentiation in Rat Visual Cortex In Vivo by Peter J. Gagolewicz, Hans C. Dringenberg

“…Interestingly, in juvenile rats, WAY 100635 application inhibited LTP, indicative of an age-dependent switch in the role of 5-HT1A receptors in gating V1 plasticity. …”
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Associations between sedentary behaviour and sarcopenia among patients aged 40 and older with chronic obstructive pulmonary disease: a cross-sectional study by Dandan Wang, Ming Zhang, Jun Huang, Haihong Zhang, Si Chen, Kefang Wang

“…Methods This is a cross-sectional survey of participants aged 40 and above with COPD, involving 27 communities and 2 hospitals’ outpatient departments. …”
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Flavonoids-rich extract of Aframomum melegueta (black pepper) improves antioxidant status and modulates aging process in lead-induced neurotoxic Drosophila melanogaster by Mohammed Sani Jaafaru

“…The expression and activities of the phase II antioxidant and age-related enzymes were determined using quantitative polymerase chain reaction (qPCR) to assess the oxidative and longevity effects of the extract. …”
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Does binge drinking between the age of 18 and 25 years predict alcohol dependence in adulthood? A retrospective case–control study in France by Marie-Pierre Tavolacci, Joel Ladner, Pierre Déchelotte, Quentin Berthon, Damiano Cerasuolo, Alexandre Baguet

“…Controls were non-alcohol-dependent adults, defined according to an Alcohol Use Disorders Identification Test score of less than 8, and were matched on age and sex with cases. Data on sociodemographics, behaviour and alcohol consumption were retrospectively collected for three life periods: before the age of 18 years; between the age of 18 and 25 years; and between the age of 25 and 45 years. …”
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A study of lipid profile peculiarities and atherogenic index of plasma in patients younger than fifty years of age with newly diagnosed rheumatoid arthritis by Varsha R. Bhatt, Kavita K. Krishna, Vishal Asrani, Rajat Chauhan

“…Aims: Evaluation of lipid profile and atherogenic index of plasma (AIP) in newly diagnosed DMARD naïve patients of RA younger than 50 years of age, and its comparison with age- and sex-matched healthy controls. …”
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Reduction of Constipating Scoring System Among Women Aged 18-25 Years Old as A Result of Decocted Trengguli (Cassia fistula L.) by Isnaini Nur Jannah, Arifa Mustika, Edith Frederika Puruhito

“…Purpose: The purpose of this study was to prove the effectiveness of decocta pulp of trengguli for the reduction of constipation scoring system among women aged 18- 25 years old with constipation problem. …”
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Middle-age cerebral small vessel disease and cognitive function in later life: a population-based prospective cohort studyResearch in context by Ali Tanweer Siddiquee, Yoon Ho Hwang, Soriul Kim, Sung Jin Shin, Ji Soo Lee, June Christoph Kang, Min-Hee Lee, Hyeon Jin Kim, Seung Ku Lee, Chol Shin

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