Evaluation of outcome relevance of quality indicators in the emergency department (ENQuIRE): study protocol for a prospective multicentre cohort study by Anna Slagman, Felix Greiner, Martin Möckel, Rainer Röhrig, Susanne Drynda, Wencke Schindler, Johannes Pollmanns, Dirk Horenkamp-Sonntag, Wiebke Schirrmeister, Ronny Otto, Jonas Bienzeisler, Saskia Drösler, Rolf Lefering, Jennifer Hitzek, Enno Swart, Felix Walcher

“…Included are all patients in 2019, who were ≥18 years of age, insured at the Techniker Krankenkasse (statutory health insurance (SHI)) and gave their written informed consent to the study.The primary objective of the study is to assess the effect of selected quality measures on patient outcome. …”
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Clinical Utility of an Alzheimer’s Disease Blood Test Among Cognitively Impaired Patients: Results from the Quality Improvement PrecivityAD2 (QUIP II) Clinician Survey Study by Mark Monane, Demetrius M. Maraganore, Robert M. Carlile, Kim G. Johnson, David A. Merrill, Darren R. Gitelman, Kenneth S. Sharlin, Lawren A. VandeVrede, Kristi K. George, Jimin Wang, Tim West, Leslie Jacobs, Philip B. Verghese, Joel B. Braunstein

“…<b>Results</b>: Patients had a median age of 74, 53% were female, and 28% were traditionally under-represented in Black, Hispanic, and Asian groups. …”
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Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study by Tamara Liana Zocche, Cláudia Maccali, Fernanda Cristina de Augustinho, Elayne Cristina de Morais Rateke, Camila Matiollo, Ariane Borgonovo Rayes, Dariana Carla Maggi, Esther Buzaglo Dantas-Corrêa, Leonardo de Lucca Schiavon, Janaina Luz Narciso-Schiavon

“…Results: Between 2011 and 2016, 280 patients were included in the study. The mean age was 55.68±11.21 years, and 71.8% were males with a mean MELD of 15.65±5.64 and 41.4% Child-Pugh C. …”
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Controls on coastal saline groundwater across North America by Daniel V Kretschmer, Holly A Michael, Nils Moosdorf, Gualbert H P Oude Essink, Marc F P Bierkens, Thorsten Wagener, Robert Reinecke

“…Despite a likely overestimation of saline interface movement, the model required 492 000 years to reach a near-steady state, indicating that the saline groundwater distribution in North America has likely been evolving since before the end of the last ice age, approximately 20 000 years ago.…”
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Making stereopsis related to the ability of ocular deviation: a new paradigm for assessment of intermittent exotropia by Jian-Bing Li, Wan-Ting Kong, Tao Shen, Yong-Guang Yuan, Chong-Lin Chen, Dan-Min Peng, Min-Tong Liang, Xuan He, Dan Luo, Jia-Yi Su, Wei Wang, Rui-Xin Wang, Xin-Ping Yu

“…RESULTS: A total of 48 patients (age range: 4-33y; 54.17% male) participated in the study. …”
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Insulin Resistance Associated with Plasma Xanthine Oxidoreductase Activity Independent of Visceral Adiposity and Adiponectin Level: MedCity21 Health Examination Registry by Masafumi Kurajoh, Shinya Fukumoto, Takayo Murase, Takashi Nakamura, Takuma Ishihara, Hirofumi Go, Kouji Yamamoto, Shinya Nakatani, Akihiro Tsuda, Tomoaki Morioka, Katsuhito Mori, Yasuo Imanishi, Masaaki Inaba, Masanori Emoto

“…Multiple regression analysis showed that HOMA-IR was significantly (p=0.020) associated with plasma XOR activity independent of other factors, including VFA and adiponectin level, as well as age, sex, alcohol drinking habit, smoking habit, alanine transaminase, HbA1c, and eGFR. …”
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Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…Secondary outcomes included inflammation levels (hs-CRP, NLR, PLR, LMR), Chair Stand Test (CST), Timed Up and Go (TUG), 36-item short-form health survey (SF-36), Exercise Adherence Rating Scale (EARS), and adverse events.ResultsA total of 121 subjects were enrolled, with an average age of 81.2 years, and 80.2% were female. The between-group mean difference in the WOMAC total score was −5.2 (95% CI −12.1 to 1.7, P = 0.140) at week 12, with Group H showing an improvement of −22.9 (95% CI −26.3 to −19.6, P &lt; 0.001) and Group C showing an improvement of −19.4 (95% CI −22.7 to −16.0, P &lt; 0.001) compared to baseline, revealing a significant group × time interaction (F (3, 356.034) = 14.425, P &lt; 0.001). …”
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Machine learning for predicting severe dengue in Puerto Rico by Zachary J. Madewell, Dania M. Rodriguez, Maile B. Thayer, Vanessa Rivera-Amill, Gabriela Paz-Bailey, Laura E. Adams, Joshua M. Wong

“…Feature importance analysis identified hemoconcentration (≥ 20% increase during illness or ≥ 20% above baseline for age and sex), leukopenia (white blood cell count < 4000/mm3), and timing of presentation at 4–6 days post-symptom onset as key predictors. …”
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Effects of Subchronic Exposure of Diclofenac on Growth, Histopathological Changes, and Oxidative Stress in Zebrafish (Danio rerio) by Eva Praskova, Lucie Plhalova, Lucie Chromcova, Stanislava Stepanova, Iveta Bedanova, Jana Blahova, Martin Hostovsky, Misa Skoric, Petr Maršálek, Eva Voslarova, Zdenka Svobodova

“…The juvenile growth tests were performed on Danio rerio according to OECD method number 215. Fish at the age of 20 days were exposed to the diclofenac environmental concentration commonly detected in the Czech rivers (0.02 mg L−1) and the range of sublethal concentrations of diclofenac (5, 15, 30, and 60 mg L−1) for 28 days. …”
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Clinicodemographic profile and predictors of poor outcome in hospitalised COVID-19 patients: a single-centre, retrospective cohort study from India by Prashant K Singh, Lokesh Tiwari, Alok Ranjan, Prakriti Gupta, Prabhat Kumar Singh, Yogesh Kumar, Yankappa N, Amrita Banerjee, C M Singh

“…Mortality rates increased with age. Death was more common among males (OR 1.51, 95% CI 1.25 to 1.81). …”
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Assessing Prevention Protocols by a Brief Questionnaire in the Infectious Respiratory Diseases Pandemics: An Application in Pedestrian Population in COVID-19 Pandemic by Ali Jafari-Khounigh, Alireza Razzaghi, Hamid Sharifi, Shahram Habibzadeh, Seyed Taghi Heydari, Rasool Entezarmahdi, Mostafa Farahbakhsh, Alireza Ansari Moghaddam, Mahdi Rezaei, Mohammad Saadati, Ehsan Sarbazi, Morteza Haghighi, Mina Golestani, Homayoun Sadeghi-Bazargani

“…A total of 324 persons from three provinces of Iran participated in this study. The mean age (SD) of participants was 41.5 (16.7). The CVR values resulted in the elimination of two questions. …”
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Evaluation of bone mineral density and its influencing factors in patients infected with HIV under antiretroviral therapy by Alireza Azarboo, Mahboobeh Hemmatabadi, Noushin Fahimfar, Zahra Faghihi, SeyedAhmad SeyedAlinaghi, Nooshin Shirzad, Ladan Abbasian

“…Methods Data were collected from individuals diagnosed with HIV aged 30–50, receiving ART for at least 6 months. …”
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Insulin Resistance Increases MRI-Estimated Pancreatic Fat in Nonalcoholic Fatty Liver Disease and Normal Controls by Niraj S. Patel, Michael R. Peterson, Grace Y. Lin, Ariel Feldstein, Bernd Schnabl, Ricki Bettencourt, Ekihiro Seki, Claude B. Sirlin, Rohit Loomba

“…Compared to healthy controls, patients with NAFLD had significantly higher pancreatic MRI-PDFF (3.6% versus 8.5%, P value <0.001), and these results remained consistent in multivariable-adjusted models including age, sex, body mass index, and diabetes (P value =0.03). …”
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Magnetic resonance imaging -based radiomics of the pituitary gland is highly predictive of precocious puberty in girls: a pilot study by Michele Maddalo, Maddalena Petraroli, Francesca Ormitti, Alice Fulgoni, Margherita Gnocchi, Marco Masetti, Eugenia Borgia, Benedetta Piccolo, Emanuela C. Turco, Viviana D. Patianna, Nicola Sverzellati, Susanna Esposito, Susanna Esposito, Caterina Ghetti, Maria E. Street, Maria E. Street

“…A predictive model based on radiomic features (RFs), extracted form magnetic resonance imaging (MRI) of the pituitary gland, was thus developed to distinguish between CPP and control subjects.Methods45 girls with confirmed diagnosis of CPP (CA:8.4 ± 0.9 yr) according to the current criteria and 47 age-matched pre-pubertal control subjects (CA:8.7 ± 1.2 yr) were retrospectively enrolled. …”
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Metformin Increases Protein Phosphatase 2A Activity in Primary Human Skeletal Muscle Cells Derived from Lean Healthy Participants by Aktham Mestareehi, Xiangmin Zhang, Berhane Seyoum, Zaher Msallaty, Abdullah Mallisho, Kyle Jon Burghardt, Anjaneyulu Kowluru, Zhengping Yi

“…Eight lean insulin-sensitive nondiabetic participants (4 females and 4 males; age: 21.0±1.0 years; BMI: 22.0±0.7 kg/m2; 2-hour OGTT: 97.0±6.0 mg/dl; HbA1c: 5.3±0.1%; fasting plasma glucose: 87.0±2.0 mg/dl; M value; 11.0±1.0 mg/kgBW/min). …”
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Whether the Indications for Reverse Shoulder Arthroplasty Should Continue to Be Expanded? A Systematic Review and Meta‐Analysis by Huankun Li, Hangsheng Bao, Zhidong Yang, Baijun Hu, Yaocheng Pan, Yi Wang, Jiayi Chen, Hongjun Chen, Bisheng Shen, Yonggen Zou

“…Further meta regression analysis was conducted, considering factors such as region, age, gender ratio, and follow‐up time, excluding the influence of relevant factors. …”
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Zoltán Kodálys Harmonielehre – ein Rekonstruktionsversuch by Anna Dalos

“…Der Beitrag spart die Harmonik in Kodálys Kompositionen bewusst aus, da dies einen eigenständigen Aufsatz erfordern würde. In 1907, at the age of 25, Zoltán Kodály began teaching music theory and composition at the Budapest Academy of Music. …”
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Analysis of the accuracy of disease prediction in pediatric ward patients based on the modified early warning score for children: A randomized controlled trialWhat is already known... by Kang Lin, Xiaojun Weng, Bing Du, Ting Tian, Xiaoxiang Quan

“…Background: Due to their young age and limited ability to communicate, pediatric patients in internal medicine wards are at risk of nursing assessment errors, which can lead to adverse events and disputes. …”
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Rate of Suture Material Absorption Does Not Impact Short Term Outcome of Tubularized Incised Plate Repair of Distal Penile Hypospadias in Children: A Randomized Controlled Study by Mohamed Abdelwahab, Mohamed Salah, Waseem Aboul Ela, Ahmed Salem, Amr Amin Ragab, Ahmed Mahmoud Shouman, Mohamed Abdelghany

“…Results: The mean ± SD age at the time of surgery for groups (A) and (B) was 46.95 ± 28.07 and 39.33± 21.63 months respectively (p = 0.353). …”
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Impacts of drought on respiratory mortality in the upper midwest United States: a population subgroup assessment by Yeongjin Gwon, Yuanyuan Ji, Jesse D Berman, Azar M Abadi, Ronald D Leeper, Jared Rennie, Jesse E Bell

“…Stratification analyses were conducted by age group, gender, race, urbanicity, and state within the region. …”
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