Sex differences in intracranial plaque burden in patients with type 2 diabetes mellitus with acute ischemic cerebrovascular disease: a pilot study based on high-resolution MRI by Xuejiao Yan, Ling Li, Jie Gao, Lihui Wang, Kai Ai, Xiaoyan Lei, Min Tang, Xiaoling Zhang, Dongsheng Zhang

“…Poisson regression models or negative binomial regression models were used to analyze the interaction between sex and treatment in relation to plaque burden.ResultsA total of 495 plaques were detected in 120 patients (75 male; mean age, 60.77 ± 11.01 years), including 311 proximal and 184 distal plaques. …”
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Case report: Novel ACTN4 variant of uncertain significance in a pediatric case of steroid-resistant nephrotic syndrome requesting kidney transplantation by Ignacio Alarcón, Carolina Peralta, Francisco Cammarata-Scalisi, Maykol Araya Castillo, Francisco Cano, Francisco Cano, Angélica Rojo, María Luisa Ceballos, María Luisa Ceballos, Paola Krall, Paola Krall

“…Within a few weeks, proteinuria rapidly increased, and a kidney biopsy exhibited FSGS features. At the age of 12, he reached ESKD and initiated peritoneal dialysis, experiencing an episode of posterior reversible encephalopathy syndrome. …”
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Anaesthesia provision, infrastructure and resources in the Heilongjiang Province, China: a cross-sectional observational study by Jian Zhang, Hui Wang, Fei Han, Ge Jiang, Xi Zhang, Guonian Wang, Xiaoyu Zheng, Jingshun Zhao, Dandan Yao, Wanchao Yang, Xuesong Ma, Xiaodi Lu, Xidong Zhu, Meijun Chen, Mingyue Zhang

“…The percentages of anaesthesiologists’ age ≥46, 36–45, 25–35 and <25 are 24.03%, 41.80%, 33.91% and 0.27%, respectively. …”
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Evolution of Liver Resection for Hepatocellular Carcinoma: Change Point Analysis of Textbook Outcome over Twenty Years by Yeshong Park, Ho-Seong Han, Seung Yeon Lim, Hyelim Joo, Jinju Kim, MeeYoung Kang, Boram Lee, Hae Won Lee, Yoo-Seok Yoon, Jai Young Cho

“…More recent time interval groups were associated with older age (59 vs. 59 vs. 61 vs. 63 years, <i>p</i> < 0.0001) and more comorbidities. …”
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Unmet Supportive Care Needs of Lung Cancer Survival Patients at Different Cancer Stages and Treatment Phases by Lee PY, Chen YA, Tsai TH, Chen CY, Shieh SH

“…Associations with sex, age, cancer stage, and treatment phase were investigated.Results: Compared with male patients, female patients exhibited fewer unmet health information needs (aOR=0.40; p=0.021). …”
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Proportion, quality of life and factors associated with perinatal urinary incontinence among pregnant women attending at Muhimbili national hospital by Geofrey P. Chiloleti, Fransia Arda Mushi, Aboud Muhsin, Ally Mwanga

“…Results A total of 354 women were approached, all of whom participated in the study. The mean age of the participants was 30 years (range 30–34 years). …”
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Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study by Xiao S, Ou J, Qiu W, Ye C, Li N, Chen S, Lai Y, Deng Z, Wu F, Shen Y

“…We explored the all-cause mortality risk of individuals with PRISm in a large sample of the general population.Methods: We used data from the National Health and Nutrition Examination Survey III and 2007– 2012. Participants aged 20– 79 years at baseline and who underwent spirometry were included. …”
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The outcomes of residual ametropia correction by LASIK and PRK on pseudophakic eyes depending on IOL model by E.P. Gurmizov, K.B. Pershin, N.F. Pashinova, A.Yu. Tsygankov

“…<br> <b>Patients and Methods:</b> 57 patients (77 eyes) after cataract surgery (n=37) or refractive lens exchange (n=40) were enrolled in this prospective open study. 45.6% were women and 54.5% were men. Mean age was 50.8±13.9 years. LASIK (n=70, 91.1%) and PRK (n=7, 8.9%) were performed using standard protocols. …”
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Comparative effectiveness of urine drug screening strategies alongside opioid agonist treatment in British Columbia, Canada: a population-based observational study protocol by Malcolm Maclure, M Eugenia Socías, Evan Wood, Paul Gustafson, Robert W Platt, Bohdan Nosyk, Jeong Eun Min, Micah Piske, Julie Bruneau, U Siebert, P Todd Korthuis, Paxton Bach, B Carolina Guerra-Alejos, Megan Kurz, Laura M Dale, X Joan Hu, Kyle Kampman, Tom Loughin

“…Our objective is to determine the safety and comparative effectiveness of alternative UDT monitoring strategies as observed in clinical practice among OAT clients in British Columbia, Canada from 2010 to 2020.Methods and analysis We propose a population-level retrospective cohort study of all individuals 18 years of age or older who initiated OAT from 1 January 2010 to 17 March 2020. …”
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Sex differences in the association between metabolic disorder and inflammatory cytokines in Han Chinese patients with chronic schizophrenia by Yinghan Tian, Yinghan Tian, Zhenkuo Li, Yun Zhang, Pei Tang, Yu Zhuang, Lewei Liu, Lewei Liu, Haojie Fan, Haojie Fan, Haojie Fan, Xianhu Yao, Wenzheng Li, Lei Xia, Lei Xia, Lei Xia, Huanzhong Liu, Huanzhong Liu, Huanzhong Liu

“…The patients with MD had higher age and duration of illness, and lower chlorpromazine equivalents and negative symptom score than those without MD. …”
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Aspartate aminotransferase to alanine aminotransferase ratio and short-term prognosis of patients with type 2 diabetes hospitalized for heart failure by Dan Liu, Li Liu, Nan Li, Yiling Zhou, Hongmei Huang, Jidong He, Heling Yao, Xiangyang Chen, Xiaochi Tang, Miye Wang, Ying Qi, Si Wang, Ye Zhu, Haoming Tian, Zhenmei An, Sheyu Li

“…Results This retrospective cohort included 8,073 patients (39.4% women) with type 2 diabetes hospitalized for heart failure. The median age was 71 years. Higher AST/ALT ratio was associated with higher risks of poor endpoints (with per standard deviation increment in AST/ALT ratio, for death within 30 days after discharge: adjusted hazard ratio [HR], 1.35, 95% confidence interval [CI], 1.21 to 1.50; for composite cardiac events: HR, 1.18, 95% CI: 1.06 to 1.31). …”
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Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…Results were analyzed using SPSS software. Result The mean age of this study population was 35.60 years with M: F ratio 1.27:1. …”
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Impact of Helicobacter pylori infection on neoadjuvant chemotherapy in locally advanced gastric cancer: a retrospective analysis by Bin Zhong, Zhizhong Xiong, Jiabo Zheng, Saddam Ahmed Mohamed, Jiachen Sun, Dayin Huang, Zijian Deng, Jianping Guo, Junsheng Peng, Huashe Wang, Lei Lian

“…Multivariate analysis showed that factors related to major pathological response included; age ≤ 50 (OR: 0.423, 95% CI: 0.194–0.925), H. pylori infection (OR: 0.396, 95% CI: 0.183–0.854), pathological stage T 3/4 (OR: 0.524, 95% CI: 0.288–0.954), and CA12-5 > 35 U/mL (OR: 0.345, 95% CI: 0.132–0.904). …”
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Hubungan Infeksi Soil Transmitted Helminth dengan Status Gizi pada Murid SDN 29 Purus Padang by Reshka Renanti M, Selfi Renita Rusdji, Elmatris SY

“…<br />Kata kunci: soil transmitted helminth, status gizi, infeksi</p><p>Abstract<br />School-age children are often exposed to a class of worm Soil Transmitted Helminth (STH) because of frequent contact with the ground. …”
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Predictive modelling and identification of critical variables of mortality risk in COVID-19 patients by Olawande Daramola, Tatenda Duncan Kavu, Maritha J. Kotze, Jeanine L. Marnewick, Oluwafemi A. Sarumi, Boniface Kabaso, Thomas Moser, Karl Stroetmann, Isaac Fwemba, Fisayo Daramola, Martha Nyirenda, Susan J. van Rensburg, Peter S. Nyasulu

“…By using the Shapley Additive exPlanations (SHAP) model to interpret the mortality risk predictions, we identified the Length of stay (LOS) in the hospital, LOS in the ICU, Time to ICU from admission, days discharged alive or death, D-dimer (blood clotting factor), and blood pH as the six most critical variables for mortality risk prediction. Also, Age at admission, Pf ratio (PaO2/FiO2 ratio), troponin T (TropT), ferritin, ventilation, C-reactive protein (CRP), and symptoms of acute respiratory distress syndrome (ARDS) were associated with the severity and fatality of COVID-19 cases. …”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…Methods A prospective, population-based study of random samples of the population (age 16–69 years) was performed within The Obstructive Lung Disease in Northern Sweden (OLIN) study and West Sweden Asthma Study (WSAS). …”
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Associations Between Patient-Reported Nutritional Status, Toxicity, and Survival in Limited-Stage SCLC by Evgenia Taranova, Marianne Aanerud, MD, PhD, Tarje O. Halvorsen, MD, PhD, Kristin T. Killingberg, MD, PhD, Marit Slaaen, MD, PhD, Bjørn H. Grønberg, MD, PhD

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Immunogenicity of the 9-valent human papillomavirus vaccine: Post hoc analysis from five phase 3 studies by Anna R. Giuliano, Joel M. Palefsky, Stephen E. Goldstone, Jacob Bornstein, Ilse De Coster, Ana María Guevara, Ole Mogensen, Andrea Schilling, Pierre Van Damme, Corinne Vandermeulen, Misoo C. Ellison, Susan Kaplan, Jianxin Lin, Rachael Bonawitz, Alain Luxembourg

“…Covariates considered were age, gender, sexual orientation, region of residence, and race. …”
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Candidate SNP markers of changes in the expression levels of the human <i>SCN9A</i> gene as a hub gene for pain generation, perception, response and anesthesia by P. A. Dotsenko, K. A. Zolotareva, R. A. Ivanov, I. V. Chadaeva, N. L. Podkolodnyy, V. A. Ivanisenko, P. S. Demenkov, S. A. Lashin, M. P. Ponomarenko

“…First, with our tool called OrthoWeb, we estimated the phylostratigraphic age indices (PAIs) for each of the genes, that is, identified the taxon of the most recent common ancestor of the organisms for which that gene has been sequenced. …”
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Efficacy of intermittent fasting on improving liver function in individuals with metabolic disorders: a systematic review and meta-analysis by Mousa Khalafi, Sara K Rosenkranz, Faeghe Ghasemi, Shokoufeh Kheradmand, Aref Habibi Maleki, Mallikarjuna Korivi, Jung-Piao Tsao

“…Subgroup analyses showed that IF decreased liver fat and ALT significantly, independent of IF mode, participant age, health status, weight status, and intervention duration. …”
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