Integrating Videoconferencing Therapist Guidance Into Stepped Care Internet-Delivered Cognitive Behavioral Therapy for Child and Adolescent Anxiety: Noninferiority Randomized Contr... by Sonja March, Susan H Spence, Larry Myers, Martelle Ford, Genevieve Smith, Caroline L Donovan

“…MethodsParticipants included 137 Australian children and adolescents aged 7 to 17 years (male: n=61, 44.5%) with a primary anxiety disorder who were recruited from participants presenting to the BRAVE Online website. …”
Get full text

Increased risk for alcohol- and other substance-exposed pregnancies among women who smoke tobacco: A secondary analysis of a primary care-based intervention by Thomas F. Northrup, Angela L. Stotts, Stephen M. Fischer, Kirk L. von Sternberg, Mary M. Velasquez

“…Material and Methods Eligible women (N=261) were recruited from 12 primary care clinics in a public healthcare system, not pregnant, aged 18–44 years, drinking >3 drinks/ day or >7 drinks/week, sexually active, and not using effective contraception. …”
Get full text

Usability and Usefulness of a Symptom Management Coaching System for Patients With Cancer Treated With Immune Checkpoint Inhibitors: Comparative Mixed Methods Study by Savannah Lucia Caterina Glaser, Itske Fraterman, Noah van Brummelen, Valentina Tibollo, Laura Maria Del Campo, Henk Mallo, Sofie Wilgenhof, Szymon Wilk, Vitali Gisko, Vadzim Khadakou, Ronald Cornet, Manuel Ottaviano, Stephanie Medlock

“…ResultsWe included 21 participants in the study, aged 29 to 73 years; 13 participants who had received immunotherapy and 8 participants who had not received immunotherapy. …”
Get full text

Efficacy and Safety of Non-Vitamin K Anticoagulants for Atrial Fibrillation in Relation to Different Renal Function Levels: A Network Meta-Analysis by Hao Jin, Kongbo Zhu, Lina Wang, Yifan Li, Jingjun Meng, Hong Zhi

“…And it does not coincide with patients taking dabigatran 110 mg with dose reduction for other factors including aged ≥75 years, renal impairment (CrCL 30–50 mL/min), gastritis, esophagitis, or gastroesophageal reflux, receiving concomitant verapamil, and so on. …”
Get full text

Un programme d’éducation à l’environnement en RDC : la malle pédagogique « les grands singes et leur habitat », présentation des résultats d’une campagne de sensibilisation en pays... by Louis Ledo, Jean Christophe Bokika Ngawolo, Samy Mankoto, Richard Dumez, Sabrina Krief

“…Ainsi, l’analyse de 288 fiches de suivi d’impact d’élèves âgés entre 10 et 18 ans révèle que le bonobo est perçu comme « laid » ; « fort » ; « gros » et « méchant ». …”
Get full text

TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles by Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Konstantina Psatha, Dimitris Kletsas, Michalis Aivaliotis, Carl-Henrik Heldin, Aristidis Moustakas

Get full text

Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“…ResultsAnalysis of 10,033 psychiatric e-referrals revealed that 58.99% (n=5918) were for patients aged 18‐44 years, 63.93% (n=6414) were for men, and 87.10% (n=8739) were for Saudi nationals. …”
Get full text

Nomogram to predict 3 month prognosis of acute ischemic stroke among young adults by Qian He, Qian He, Miaoran Wang, Haoyue Zhu, Ying Xiao, Rui Wen, Xiaoqing Liu, Yangdi Shi, Linzhi Zhang, Bing Xu

“…ObjectiveThis study aimed to develop and validate a nomogram for predicting the risk of 3 months adverse outcomes among young adults with acute ischemic stroke (AIS).MethodsPatients aged between 18 and 50 with acute ischemic stroke (AIS) at the Shenyang First’s People Hospital, between January 1st 2017 to May 30th 2023 were included in this retrospective study. …”
Get full text

The Influence of Depression, Anxiety, and Stress on Ageism Among Undergraduates: Mediating Roles of Life Satisfaction, Gratitude, and Prosociality by Chen S, Wan Z

“…Se Chen,1 Zhonglei Wan2 1School of International Education, Jiangxi Science and Technology Normal University, Nanchang, Jiangxi, People’s Republic of China; 2Department of General Education, Jiangxi Youth Vocational College, Nanchang, Jiangxi, People’s Republic of ChinaCorrespondence: Se Chen, Jiangxi Science and Technology Normal University, 589 Xuefu Avenue, Nanchang, Jiangxi Province, 330038, People’s Republic of China, Tel +0086 – 18679059130, Email chense063@foxmail.comBackground: The rapid growth of the global aging population highlights the need to address ageism and promote social inclusiveness. …”
Get full text

Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us? by Iván Sanz-Muñoz, Javier Sánchez-Martínez, Carla Rodríguez-Crespo, Corina S. Concha-Santos, Marta Hernández, Silvia Rojo-Rello, Marta Domínguez-Gil, Ahmed Mostafa, Luis Martinez-Sobrido, Jose M. Eiros, Aitor Nogales

“…The aim of this study is to analyze the basal protection and presence of antibodies against IAV H5N1 and H7N9 subtypes in the population from different ages. Moreover, we have evaluated the humoral response after immunization with a seasonal influenza vaccine. …”
Get full text

Umbilical Cord Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Skin Matrix Synthesis and Pigmentation by Kee LT, Foo JB, How CW, Nur Azurah AG, Chan HH, Mohd Yunus MH, Ng SN, Ng MH, Law JX

“…Li Ting Kee,1 Jhi Biau Foo,2– 4 Chee Wun How,5 Abdul Ghani Nur Azurah,6 Hong Hao Chan,5 Mohd Heikal Mohd Yunus,7 See Nguan Ng,8 Min Hwei Ng,1 Jia Xian Law1 1Department of Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia; 2School of Pharmacy, Taylor’s University, Subang Jaya, Selangor, Malaysia; 3Digital Health and Medical Advancements Impact Lab, Taylor’s University, Subang Jaya, Selangor, Malaysia; 4Non-Destructive Biomedical and Pharmaceutical Research Centre, Smart Manufacturing Research Institute, Universiti Teknologi MARA Selangor Campus, Puncak Alam, Selangor, Malaysia; 5School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia; 6Department of Obstetrics and Gynaecology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia; 7Department of Physiology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia; 8Ming Medical Sdn Bhd, Petaling Jaya, Selangor, MalaysiaCorrespondence: Jia Xian Law, Department of Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia, Email lawjx@hctm.ukm.edu.myIntroduction: Research has unveiled the remarkable properties of extracellular vesicles derived from mesenchymal stromal cells (MSCs), particularly in promoting wound healing, aiding re-epithelialization, revitalizing aging skin, and inhibiting hyperpigmentation. However, investigations into the potential of small extracellular vesicles from umbilical cord-derived MSCs (UC-MSC-sEVs) in reducing scarring and preventing hyperpigmentation remain limited. …”
Get full text

The Association of Cell-Free LncH19 and miR-29b Expression with the PI3K/AKT/HIF-1/VEGF Pathway in Patients with Diabetic Nephropathy: In Silico Prediction and Clinical Validation by Noha M. Abd El-Fadeal, Basma Osman Sultan, Asmaa K. K. AbdelMaogood, Essam Al Ageeli, Fatma Tohamy Mekhamer, Sherihan Rohayem, Ahmed Shahidy, Nora Hosny, Manal S. Fawzy, Mohammed M. Ismail, Hidi A. A. Abdellatif

Get full text

Regular versus as-needed treatments for mild asthma in children, adolescents, and adults: a systematic review and network meta-analysis by Prapaporn Pornsuriyasak, Sunatee Sa-nguansai, Kunlawat Thadanipon, Pawin Numthavaj, Gareth J. McKay, John Attia, Ammarin Thakkinstian

“…We aimed to update the evidence on the efficacy and safety of ICS-containing regimens, leukotriene receptor antagonists (LTRA), and tiotropium relative to as-needed (AN) short-acting β2-agonists (SABA) in children (aged 6–11 years) and adolescents/adults. Methods A systematic review of randomized controlled trials (RCTs) of regular and AN treatment for mild asthma was conducted (CRD42022352384). …”
Get full text

Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults by Clément Lanfranchi, Nadège Zanou, Jérôme Feige, Umberto DeMarchi, Aurélie Hermant, Ornella Cominetti, Eugenia Migliavacca, Alba Moreno-Asso, Astrid Hostrman, Sara Mistro, Nicolas Place

“…Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance. …”
Get full text

Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children by Ana Torres-Costoso, Vicente Martínez-Vizcaíno, Andreia Oliveira, Mairena Sánchez-López, Eva Rodríguez-Gutiérrez, Sergio Núñez de Arenas-Arroyo, Montserrat Solera-Martínez, Blanca Notario-Pacheco, Vanessa Martínez-Madrid, Arthur Eumann Mesas

“…Methods Cardiometabolic risk factors (plasma insulin levels, homeostatic model assessment for insulin resistance, mean arterial blood pressure (MAP), waist circumference (WC), and cardiorespiratory fitness (CRF)) were examined in 3417 Spanish schoolchildren aged 8–11 years. The children were categorized into four subgroups (low vs. high) based on the cutoff of ≥ 110 mg/dL for LDL-c and of ≥ 15 mg/dL for RC to define higher levels, and ANCOVA models were applied to assess the role of both lipid parameters in cardiometabolic risk. …”
Get full text

Are changes in pain intensity related to changes in balance control in individuals with chronic non-specific low back pain? A systematic review and meta-analysis by Daniel K.Y. Zheng, Jae Q.J. Liu, Jeremy R. Chang, Jeffrey C.Y. Ng, Zhixing Zhou, Jinlong Wu, Chelsia K.C. Cheung, Frank F. Huang, Sabina M. Pinto, Dino Samartzis, Manuela L. Ferreira, Kanchana Ekanayake, Stephen Lord, Xueqiang Wang, Arnold Y.L. Wong

Get full text

A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study by Aoyu Li, Jingwen Li, Yishan Hu, Yan Geng, Yan Qiang, Juanjuan Zhao

“…MethodsWe recruited 843 participants aged 60 years and older from the geriatrics and neurology departments of our collaborating hospitals, who were randomly divided into a development dataset (674/843 participants) and an internal test dataset (169/843 participants) at a 4:1 ratio. …”
Get full text

The hidden crisis: double burden of malnutrition among refugee children in South Asia – a systematic review and meta-analysis from observational studies by Pooja Panchal, Mohd Usman, Tajung Longkumer, Reshma Susan Babu, Mahalaqua Nazil Khatib, Shariza Abdul Razak, Kavitha Menon

“…The 10 studies covered a total of 4,274 participants with 3,536 urban and 738 rural refugee children aged between 0 and 19 years [refugee children (n = 8) and refugee adolescents (n = 2)]. …”
Get full text

Studying and enhancing the methods for distance teaching of computer science in Kazakh secondary school students during the pandemic by M. M. Zhamankarin, A. M. Sivinskiy, M. K. Aitkenova, M. B. Zhanibekov

“…At the moment of the experiment, the students were aged 12 to 18 years old. The participants were divided into seven groups according to the educational level (5th–11th forms) in order to make it more convenient to trace qualitative changes in the academic progress depending on the selected method for distance teaching of computer science. …”
Get full text

Comparing the Institution-based Supervision and Tele-based Supervision for Task-oriented Exercises on Upper Limb Motor Performance and Functional Ability among Stroke Patients: A R... by Neha, Subhasish Chatterjee

“…A total of 62 male and female patients, aged 45-75 years, who have experienced their first ischaemic or haemorrhagic stroke within the last six months and have scores ranging from 26 to 56 on the Fugl-Meyer Assessment for Upper Extremity (FMA-UE), mild to moderate spasticity (less than 2 on the Modified Ashworth Scale (MAS), >24 on the Mini-mental State Examination (MMSE), and stages II and III of the Brunnstrom score will be included in the study. …”
Get full text