Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites by Yun Teng, Chao Luo, Xiaolan Qiu, Jingyao Mu, Mukesh K. Sriwastva, Qingbo Xu, Minmin Liu, Xin Hu, Fangyi Xu, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Maiying Kong, Zhanxu Liu, Xiang Zhang, Raobo Xu, Jun Yan, Michael L. Merchant, Craig J. McClain, Huang-Ge Zhang

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Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults by Timothy D. Verstynen, Brighid Lynch, Destiny L. Miller, Michelle W. Voss, Ruchika Shaurya Prakash, Laura Chaddock, Chandramallika Basak, Amanda Szabo, Erin A. Olson, Thomas R. Wojcicki, Jason Fanning, Neha P. Gothe, Edward McAuley, Arthur F. Kramer, Kirk I. Erickson

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Highly pathogenic avian H5N1 influenza A virus replication in ex vivo cultures of bovine mammary gland and teat tissues by Masaki Imai, Hiroshi Ueki, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Maki Kiso, Asim Biswas, Sanja Trifkovic, Nigel Cook, Peter J. Halfmann, Gabriele Neumann, Amie J. Eisfeld, Yoshihiro Kawaoka

“…Here, we compared the replicative capacity of A/dairy cattle/Texas/24-008749-001/2024 (H5N1; Cow-H5N1) isolated from a dairy cow, A/chicken/Ghana/AVL-76321VIR7050-39/2021 (H5N1; Chicken-H5N1) isolated from a chicken, and a human H1N1 2009 pandemic virus in ex vivo explant cultures of mammary gland and teat from lactating cows. …”
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Tolerability and Effectiveness of Regorafenib Treatment in Patients with Unresectable Hepatocellular Carcinoma: Real-World Data from the United States by Finn RS, Iyer R, Kalman RS, Parikh ND, Cabrera R, Babajanyan S, Kaseb AO

“…Richard S Finn,1 Renuka Iyer,2 Richard S Kalman,3 Neehar D Parikh,4 Roniel Cabrera,5 Svetlana Babajanyan,6 Ahmed O Kaseb7 1Department of Medicine, University of California, Los Angeles, CA, USA; 2Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA; 3Department of Medicine, Einstein Medical Center, Philadelphia, PA, USA; 4Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA; 5Department of Medicine, University of Florida Health, Gainesville, FL, USA; 6US Medical Affairs, Oncology, Bayer Healthcare, Whippany, NJ, USA; 7Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence: Richard S Finn, Department of Medicine, University of California, Los Angeles, CA, USA, Tel +1-310-586-2091, Email rfinn@mednet.ucla.eduIntroduction: While several systemic therapies are available for unresectable hepatocellular carcinoma (uHCC), there is a lack of granular real-world evidence to support the efficacy and safety of these therapies. …”
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A maturity model for Clinical Trials Management Ecosystem by Shruti Sehgal, E. Chris Pua, Svetlana Rojevsky, Michael J. Becich, Joshua Fehrmann, Boyd M. Knosp, Adam Wilcox, Jeffery C. Talbert, Catherine K. Craven, Justin Starren

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Assessing survey design changes of long-term fishery-independent groundfish trawl surveys in the Gulf of Mexico by Adam G. Pollack, Eric R. Hoffmayer, Theodore S. Switzer, David S. Hanisko, Jill M. Hendon, John Mareska, Fernando Martinez-Andrade, Jeff Rester, Zachary C. Zuckerman, Gilmore Pellegrin

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First Results from the JWST Early Release Science Program Q3D: The Fast Outflow in a Red Quasar at z = 0.44 by Weizhe Liu, Sylvain Veilleux, Swetha Sankar, David S. N. Rupke, Nadia L. Zakamska, Dominika Wylezalek, Andrey Vayner, Caroline Bertemes, Yuzo Ishikawa, Yu-Ching Chen, Jenny E. Greene, Timothy Heckman, Guilin Liu, Hsiao-Wen Chen, Dieter Lutz, Sean D. Johnson, Nicole P. H. Nesvadba, Patrick Ogle, Nadiia Diachenko, Andy D. Goulding, Kevin N. Hainline, Fred Hamann, Hui Xian Grace Lim, Nora Lützgendorf, Vincenzo Mainieri, Ryan McCrory, Grey Murphree, Lu Shen, Eckhard Sturm, Lillian Whitesell

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Discovering Large-scale Structure at 2 < z < 5 in the C3VO Survey by Denise Hung, Brian C. Lemaux, Olga Cucciati, Ben Forrest, Ekta A. Shah, Roy R. Gal, Finn Giddings, Derek Sikorski, Emmet Golden-Marx, Lori M. Lubin, Nimish Hathi, Giovanni Zamorani, Lu Shen, Sandro Bardelli, Letizia P. Cassarà, Gabriella De Lucia, Fabio Fontanot, Bianca Garilli, Lucia Guaita, Michaela Monika Hirschmann, Kyoung-Soo Lee, Andrew B. Newman, Vandana Ramakrishnan, Daniela Vergani, Lizhi Xie, Elena Zucca

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The association of origin and environmental conditions with performance in professional IRONMAN triathletes by Beat Knechtle, Mabliny Thuany, David Valero, Elias Villiger, Pantelis T. Nikolaidis, Marilia S. Andrade, Ivan Cuk, Thomas Rosemann, Katja Weiss

“…Most of the athletes competed in IRONMAN Hawaii (925), IRONMAN Florida (563), IRONMAN Austria (452), IRONMAN France (354), IRONMAN Wisconsin (330), IRONMAN Lanzarote (322) and IRONMAN Texas (313). The Decision Tree and the XG Boost models were the best performing models (r2 = 0.48) and rated the relative feature importances in the order gender, country of origin, water temperature, air temperature and event location. …”
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Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers by Daehwan Kim, Heekyung Chung, Wen Liu, Kangjin Jeong, Tugba Y. Ozmen, Furkan Ozmen, Matthew J. Rames, Sangyub Kim, Xiao Guo, Nathan Jameson, Petrus R. de Jong, Steven Yea, Laurie Harford, Jiali Li, Cara A. Mathews, Deborah B. Doroshow, Vincent J. Charles, Doris Kim, Kimberlee Fischer, Ahmed A. Samatar, Adrian Jubb, Kevin D. Bunker, Kimberly Blackwell, Fiona Simpkins, Funda Meric-Bernstam, Gordon B. Mills, Olivier Harismendy, Jianhui Ma, Mark R. Lackner

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Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients by Harry Pickering, Joanna Schaenman, Hoang Van Phan, Cole Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Iván Agudelo Higuita, Mark A. Atkinson, Scott Brakenridge, Monica Fung, William Messer, IMPACC Network, Ramin Salehi-rad, Matthew C. Altman, Patrice M. Becker, Steven E. Bosinger, Walter Eckalbar, Annmarie Hoch, Naresh Doni Jayavelu, Seunghee Kim-Schulze, Meagan Jenkins, Steven H. Kleinstein, Florian Krammer, Holden T. Maecker, Al Ozonoff, Joann Diray-Arce, Albert Shaw, Lindsey Baden, Ofer Levy, Elaine F. Reed, Charles R. Langelier

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Prolonged Cardiopulmonary Bypass Time-Induced Endothelial Dysfunction via Glypican-1 Shedding, Inflammation, and Matrix Metalloproteinase 9 in Patients Undergoing Cardiac Surgery by Shiyi Li, Katherine V. Nordick, Iván Murrieta-Álvarez, Randall P. Kirby, Rishav Bhattacharya, Ismael Garcia, Camila Hochman-Mendez, Todd K. Rosengart, Kenneth K. Liao, Nandan K. Mondal

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Risk factor for intestinal carriage of carbapenem-resistant Acinetobacter baumannii and the impact on subsequent infection among patients in an intensive care unit: an observationa... by Li Wei, Lin Cai, Shan Gao, Fu Qiao, Wenzhi Huang, Shichao Zhu, Yan Kang, Chuanmin Tao, Zhiyong Zong

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Unintended pregnancy among women living with HIV and its predictors in East Africa, 2024. A systematic review and meta-analysis. by Eyob Shitie Lake, Mulat Ayele, Abebaw Alamrew, Befikad Derese Tilahun, Besfat Berihun Erega, Alemu Birara Zemariam, Getinet Kumie, Gizachew Yilak

“…The extracted Microsoft Excel spreadsheet data were imported into the STATA software version 17 (STATA Corporation, Texas, USA) for analysis. A random-effects model was used to estimate the pooled prevalence of unintended pregnancy among women living with HIV in East Africa. …”
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Ezrin Polarization as a Diagnostic Marker for Circulating Tumor Cells in Hepatocellular Carcinoma by Ibrahim Büdeyri, Olaf Guckelberger, Elsie Oppermann, Dhruvajyoti Roy, Svenja Sliwinski, Felix Becker, Benjamin Struecker, Thomas J. Vogl, Andreas Pascher, Wolf O. Bechstein, Anna Lorentzen, Mathias Heikenwalder, Mazen A. Juratli

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Entrepreneurship education for women through project-based flipped learning: The impact of innovativeness and risk-taking on course satisfaction by Seung-chul Yoo, Tu Anh Truong, Kwanghee Jung

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Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain by Andrew Silberfeld, James M. Roe, Jacob Ellegood, Jason P. Lerch, Lily Qiu, Yongsoo Kim, Jong Gwan Lee, William D. Hopkins, Joanes Grandjean, Yangming Ou, Olivier Pourquié

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Dependencia funcional en pacientes adultos mayores con diabetes mellitus tipo 2 en Lima, Perú by José Gálvez, Ericson Gutiérrez, Fernando Runzer Colmenares, José Parodi

“…<br /><strong>Método:</strong> se realizó un estudio transversal con análisis secundario de la base de datos Texas-Camena UTMB 2010-2015 del Centro de Investigación del Envejecimiento de la Universidad San Martín de Porres. …”
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The effectiveness of providing training and ongoing support to foster cultural humility in volunteers serving as mentors to youth of color: a mixed-methods study protocol by Bernadette Sánchez, Amy J. Anderson, Carla Herrera, David L. DuBois, Kay Thursby Bourke, Jean K. Sack, So Jung Lee, Karen Burchwell, Lidia Y. Monjaras-Gaytan, Yesenia Garcia-Murillo

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Direct-Acting Oral Anticoagulants in the Management of Cerebral Venous Sinus Thrombosis—Where Do We Stand? by Nikhil Vojjala, Supriya Peshin, Lakshmi Prasanna Vaishnavi Kattamuri, Rabia Iqbal, Adit Dharia, Jayalekshmi Jayakumar, Rafi Iftekhar, Shagun Singh, Mamtha Balla, Claudia S. Villa Celi, Ramya Ramachandran, Rishab Prabhu, Sumeet K. Yadav, Geetha Krishnamoorthy, Vijendra Singh, Karan Seegobin

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