Orthogonal validation of PROTAC mediated degradation of the integral membrane proteins EGFR and c-MET by Camilla Ruffilli, Sascha Röth, Noam Zelcer, Kevin Moreau

Subjects: Get full text

PROTACs: Mechanism and Bioavailability enhancement strategies by nanotechnology, RNA viral infections (vaccine strategy) and Prodrug development by Sanaul Mustafa, Md Sabir Hussain Siddiquee

Subjects: Get full text

A new peptide inhibitor of C1QBP exhibits potent anti‐tumour activity against triple negative breast cancer by impairing mitochondrial function and suppressing homologous recombina... by Xingxing Li, Yue Wu, Min Zhang, Fengliang Wang, Hong Yin, Yanrong Zhang, Shuli Zhao, Jiehua Ma, Mingming Lv, Cheng Lu

Subjects: Get full text

Influenza A virus hemagglutinin: from classical fusion inhibitors to proteolysis targeting chimera-based strategies in antiviral drug discovery by Francisco Javier Hermoso-Pinilla, Aitor Valdivia, María-José Camarasa, Tiziana Ginex, Francisco Javier Luque

Subjects: Get full text

Antibody-mediated degradation of 4R-tau restores mitochondrial membrane polarization in human induced pluripotent stem cell-derived neurons with the MAPT 10+16 mutation by Dale O. Starkie, Charles Arber, Terry Baker, Daniel J. Lightwood, Selina Wray

Subjects: Get full text

New strategies to enhance the efficiency and precision of drug discovery by Qi An, Liang Huang, Chuan Wang, Dongmei Wang, Yalan Tu

Subjects: Get full text

Non-enzymatic protein targeting agents as a promising strategy for cancer treatment by Madison Ambrose, Jeremy Lee, Aleem Syed, Zamal Ahmed, Guang Peng

Subjects: Get full text