ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats by Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali

Subjects: Get full text

Colonic strictures in Crohn’s disease: a non-surgical survival by Sarra Laabidi, Hamed Aboubecrine, Salma Souissi, Donia Gouiaa, Asma Labidi, Nadia Ben Mustapha, Anis Haddad, Amine Sebai, Meriem Serghini, Monia Fekih, Hanene Jaziri, Jalel Boubaker

Subjects: Get full text

Elevated Circulating IL-1<mml:math> <mml:mi>&#x03B2;</mml:mi> </mml:math> and TNF-Alpha, and Unaltered IL-6 in First-Trimester Pregnancies Complicated by Threatened Abortion With an Adverse Outcome

“…IL-1<mml:math> <mml:mi>&#x03B2;</mml:mi> </mml:math> and TNF-alpha were detected with significantly higher levels in group A, compared to all other groups. …”
Get full text

DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS by N. S. Yudin, L. A. Vasil’eva, V. A. Belyavskaya, R. B. Aitnazarov, P. N. Smirnov, M. Heaton, W. W. Laegreid, G. V. Orlova, A. G. Romashchenko, M. I. Voevoda

Subjects: Get full text

MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

Subjects: “…tumor necrosis factor-alpha (TNF-alpha)…”
Get full text

Value of Caffeic Acid Phenethyl Ester Pretreatment in Experimental Sepsis Model in Rats by Ozlem Alici, Havva Sahin Kavakli, Cemile Koca, Neriman Defne Altintas, Murat Aydin, Suleyman Alici

“…Our results demonstrate that CAPE may have a beneficial effect on ET and TNF-alpha levels and oxidative stress parameters induced by sepsis in experimental rat models. …”
Get full text

The Interaction of Oxidative Stress Response with Cytokines in the Thyrotoxic Rat: Is There a Link? by Balahan Makay, Ozer Makay, Cigdem Yenisey, Gokhan Icoz, Gokhan Ozgen, Erbil Unsal, Mahir Akyildiz, Enis Yetkin

“…Serum malondialdehyde (MDA), glutathione (GSH), glutathione reductase (GR), glutathione peroxidase (GPx), and nitric oxide derivates (NO•x), and plasma IL-6, IL-10, and TNF-alpha were measured. MDA, GSH, NO•x, IL-10, and TNF-alpha levels increased after L-thyroxine induction. …”
Get full text

Assessment of the Effects of Chemotherapy on Ovarian Reserve in Rats by Ahmet Mete Ergenoğlu, Özgür Yeniel, Volkan Turan, Gülşah Demirtaş, Levent Akman, Mustafa Coşan Terek, Gülinnaz Ercan, Osman Zekioğlu

“… OBJECTIVE: To determine the effect of cyclophosphamide and cisplatin on ovarian reserve in rats by the way of counting primordial follicle and assessing TNF-alpha, 8-OH deguanosine and oxidant/antioxidant status. …”
Get full text

Pericardial Effusion due to Infliximab Therapy for Ulcerative Colitis by Muhammad Mirza, Maira Mirza, Vagishwari Murugesan, Arrel Olano

“…Antitumor necrosis factor alpha (anti-TNF alpha) agents such as infliximab are drugs that have been used for the treatment of ulcerative colitis for decades. …”
Get full text

Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts by Claudia Casnici, Donatella Lattuada, Noemi Tonna, Katia Crotta, Claudio Storini, Fabio Bianco, Marcello Claudio Truzzi, Costantino Corradini, Ornella Marelli

“…We observed that synovial fluid is more effective in inducing cell proliferation with respect to TNF-alpha or culture medium alone. Spontaneous apoptosis in fibroblasts was also decreased in response to synovial fluid. …”
Get full text

Genetic Analysis of Cytokine Promoters in Nonhuman Primates: Implications for Th1/Th2 Profile Characteristics and SIV Disease Pathogenesis by Pavel Bostik, Melanie Watkins, Francois Villinger, Aftab A. Ansari

“…Sequence analysis of promoter fragments of IL-4, IL-10, IL-12 p40, IFN-gamma and TNF-alpha from the two monkey species showed varying degree of homology ranging from high degree of homology detected for IFN-gamma promoter (>99%) to relatively high degree of polymorphism detected for TNF-alpha promoter (94% homology). …”
Get full text

Tumor Necrosis Factor Receptor Superfamily, Member 1B Haplotypes Increase or Decrease the Risk of Inflammatory Bowel Diseases in a New Zealand Caucasian Population by Lynnette R. Ferguson, Dug Yeo Han, Claudia Huebner, Ivonne Petermann, Murray L. Barclay, Richard B. Gearry, Alan McCulloch, Pieter S. Demmers

“…Interactions between TNF-alpha and TNF-alpha receptor play a fundamental role in inflammatory response. …”
Get full text

Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats by Giuseppina Palladini, Andrea Ferrigno, Vittoria Rizzo, Eleonora Tarantola, Vittorio Bertone, Isabel Freitas, Stefano Perlini, Plinio Richelmi, Mariapia Vairetti

“…Serum levels of hepatic enzymes and TNF-alpha were concomitantly increased during hepatic I/R. …”
Get full text

Reaction of the Liver upon Long-Term Treatment of Fluoxetine and Atorvastatin Compared with Alcohol in a Mouse Model by Zhiliang Chen, Tony C. H. Chow, Shicong Wang, Gigi C. T. Leung, Sharon L. Y. Wu, David T. Yew

“…For ALT, AST, albumin, and liver TNF alpha, only the ethanol group surged to significantly higher levels. …”
Get full text

Effect of attenueted parapoxvirus ovis on levels of some serum cytokines and antibody response in sheep by Kamil Atlı, Atilla Şimşek

“…, IL-12, IFN-&gamma;, TNF-&alpha; from proinflammatory cytokines (Th1) and IL-4 and IL-10 from antiinflammatory cytokines (Th2) were determined by ELISA.…”
Get full text

Inflammatory Cytokine Pattern Is Sex-Dependent in Mouse Cutaneous Melanoma Experimental Model by Mihaela Surcel, Carolina Constantin, Constantin Caruntu, Sabina Zurac, Monica Neagu

“…In the male mice group, only circulatory KC increased 4 times, while IL-1-beta and TNF-alpha doubled their circulatory values. Various serum cytokines correlated with the disease evolution in cutaneous melanoma mouse model.…”
Get full text

The structure–activity relationship and computational studies of 1,3-thiazole derivatives as cholinesterase inhibitors with anti-inflammatory activity by Modrić, Marina, Božičević, Marin, Odak, Ilijana, Talić, Stanislava, Barić, Danijela, Mlakić, Milena, Raspudić, Anamarija, Škorić, Irena

“…In our previous research, some screened 1,3-thiazole fragments were found to be potent by inhibiting LPS-induced TNF$\alpha $ and IL-8 release with IC50 values in the $\mu $M range without cytotoxic activity. …”
Get full text

Significant Cytokine mRNA Expression Changes Immediately after Initiation of Cardiopulmonary Resuscitation by Mareen Braunstein, Martina Williamson, Thomas Kusmenkov, Jürgen Landes, Peter Biberthaler, Karl-Georg Kanz, Wolfgang Böcker, Viktoria Bogner

“…Results. 25 patients (63 ± 15 years) were enrolled presenting a characteristic time-dependent cytokine profile in the early postresuscitation period. High initial TNF-alpha and IL-8 mRNA levels were followed by a significant decrease. …”
Get full text

Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress by Giuseppina Palladini, Laura G. Di Pasqua, Clarissa Berardo, Veronica Siciliano, Plinio Richelmi, Stefano Perlini, Andrea Ferrigno, Mariapia Vairetti

“…Serum hepatic enzymes and TNF-alpha were assessed. An increase in gelatinase activity in the NASH model occurred in RL compared with ML. …”
Get full text

Chemokine Profiles Are Affected in Serum of Patients with Acute Rejection of Kidney Allograft by Lenka Krupickova, Martina Fialova, Marek Novotny, Veronika Svachova, Kristyna Mezerova, Eva Cecrdlova, Ondrej Viklicky, Ilja Striz

“…In our in vitro model with TNF alpha induction, renal proximal epithelial cells seemed to be a more potent source of chemokines attracting neutrophils as compared to monocyte/macrophage cell line but the coculture of these cells potentiated release of neutrophilic chemokines CXCL5 and CXCL6. …”
Get full text