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Tumor microenvironment and immunotherapy for triple-negative breast cancer
Published 2024-12-01Subjects: “…Triple-negative breast cancer (TNBC)…”
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The potential benefits of radiotherapy in elderly patients with early-stage triple-negative breast cancer
Published 2025-01-01Subjects: “…triple-negative breast cancer (TNBC)…”
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Function of vasohibin-2 and the mechanism of alternative splicing in triple-negative breast cancer
Published 2024-12-01Subjects: “…triple-negative breast cancer (tnbc)…”
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Clinical Characteristics in Patients with Triple Negative Breast Cancer
Published 2017-01-01“…The purpose of this study was to compare and contrast the clinical characteristics of the triple negative breast cancer (TNBC) and non-TNBC patients, with a particular focus on genetic susceptibility and risk factors prior to diagnosis. …”
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Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway
Published 2025-01-01“…IntroductionTriple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer to treat. …”
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Network Pharmacology, Molecular Docking, and Molecular Dynamics Analysis of Honokiol against Triple-negative Breast Cancer
Published 2024-12-01“…Introduction: Triple-negative breast cancer (TNBC) persists as a formidable clinical obstacle due to its aggressive nature and the scarcity of effective treatment modalities. …”
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The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer
Published 2025-01-01“…BackgroundTriple-negative breast cancer (TNBC) is a heterogeneous disease with a worse prognosis. …”
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Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting
Published 2025-01-01“…The therapeutic effects of PA may vary across different subtypes of TNBC such as TNBC-BL1, TNBC-Metaplastic, and TNBC-BL2. …”
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Clinicopathological and Prognostic Characteristics of Malaysian Triple Negative Breast Cancer Patients Undergoing TAC Chemotherapy Regimen
Published 2020-01-01“…Triple negative breast cancer (TNBC) is associated with aggressive tumour phenotype and early tumour relapse following diagnosis. …”
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FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancer
Published 2025-01-01“…Abstract Background Dysregulated energy metabolism has emerged as a defining hallmark of cancer, particularly evident in triple-negative breast cancer (TNBC). Distinct from other breast cancer subtypes, TNBC exhibits heightened glycolysis and aggressiveness. …”
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RSL3 induces ferroptosis by activating the NF-κB signalling pathway to enhance the chemosensitivity of triple-negative breast cancer cells to paclitaxel
Published 2025-01-01“…Abstract Chemotherapy resistance in triple-negative breast cancer (TNBC) leads to poor therapeutic effects and a poor prognosis. …”
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SHP2 promotes the epithelial-mesenchymal transition in triple negative breast cancer cells by regulating β-catenin
Published 2025-01-01“…Results We found that high SHP2 expression was associated with a poor prognosis in patients with TNBC. The migratory and invasive abilities of TNBC cells in vitro, as well as the metastatic potential of TNBC in mouse xenograft models, were reduced after SHP2 depletion. …”
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Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality
Published 2025-01-01“…We profiled circulating immune cells in stage I–III and stage IV triple-negative breast cancer (TNBC) patients and healthy donors (HDs). Metastatic TNBC (mTNBC) patients had reduced T cells, dendritic cells, and differentiated B cells compared to non-metastatic TNBC patients and HDs, partly linked to prior chemotherapy. …”
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The mechanism underlying metastasis in triple-negative breast cancer: focusing on the interplay between ferroptosis, epithelial-mesenchymal transition, and non-coding RNAs
Published 2025-01-01“…Triple-negative breast cancer (TNBC) is a type of breast cancer with lack the expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). …”
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Hypoxic BMSC-derived exosomal miR-210-3p promotes progression of triple-negative breast cancer cells via NFIX-Wnt/β-catenin signaling axis
Published 2025-01-01“…Deletion of miR-210-3p in hypoxic BMSC-derived exosomes attenuates TNBC in vivo. Additionally, human exosomal miR-210-3p from the serum of TNBC patients promotes TNBC progression. …”
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A novel lncRNA AC112721.1 promotes the progression of triple-negative breast cancer by directly binding to THBS1 and regulating miR-491-5p/C2CD2L axis
Published 2024-12-01“…Abstract Triple-negative breast cancer (TNBC) seriously threatens women’s health, and long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression and play fundamental roles in TNBC. …”
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GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis
Published 2024-12-01“…Abstract Background Triple negative breast cancer (TNBC) belongs to the worst prognosis of breast cancer subtype probably because of distant metastasis to other organs, e.g. lungs. …”
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Ultrafast dynamic contrast-enhanced breast MRI with quantitative perfusion parameters in differentiating breast cancer: a study focusing on triple-negative and HER2 positive breast...
Published 2025-01-01“…The carcinomas were segregated into respective subgroups (HER2+ vs HER2-, TNBC vs non-TNBC, HER2+ vs TNBC) and we compared the eight parameters across these groups. …”
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Outcome for Patients with Triple-Negative Breast Cancer Is Not Dependent on Race/Ethnicity
Published 2012-01-01“…Triple negative breast cancer (TNBC) is biologically aggressive and is associated with a worse prognosis. …”
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