Improving Geldanamycin Production in <i>Streptomyces geldanamycininus</i> Through UV Mutagenesis of Protoplast by Yuan Yuan, Lu Yang, Zhikai Fang, Haimin Chen, Fei Sun, Hong Jiang, Jian Zhou

“…Multi-omic analysis revealed that the high-yielding geldanamycin in mutant strain 53 could upregulate <i>GdmG</i> and <i>GdmX</i> by 1.59 and 2.38 times in the ansamycin synthesis pathway, and downregulate <i>pks12</i>, <i>pikAI</i>, and <i>pikAII</i> by 0.25, 0.37, and 0.48 times in the fatty acid synthesis pathway, which was crucial for geldanamycin production. …”
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The Microlensing Event Rate and Optical Depth from MOA-II 9 Yr Survey Toward the Galactic Bulge by Kansuke Nunota, Takahiro Sumi, Naoki Koshimoto, Nicholas J. Rattenbury, Fumio Abe, Richard Barry, David P. Bennett, Aparna Bhattacharya, Akihiko Fukui, Ryusei Hamada, Shunya Hamada, Naoto Hamasaki, Yuki Hirao, Stela Ishitani Silva, Yoshitaka Itow, Yutaka Matsubara, Shota Miyazaki, Yasushi Muraki, Tsutsumi Nagai, Greg Olmschenk, Clement Ranc, Yuki K. Satoh, Daisuke Suzuki, Paul. J. Tristram, Aikaterini Vandorou, Hibiki Yama, (MOA collaboration)

“…In the central region with ∣ l ∣ < 5°, we estimate an optical depth of $\tau =[1.75\pm 0.04]\times 1{0}^{-6}\exp [(0.34\pm 0.02)({3}^{\circ }-| b| )]$ and an event rate of Γ = [16.08 ± 0.28] × 10 ^−6 $\exp [(0.44\pm 0.02)({3}^{\circ }-| b| )]{\mathrm{star}}^{-1}\,{\mathrm{yr}}^{-1}$ using a sample consisting of 3525 microlensing events, with Einstein radius crossing times of t _E  < 760 days and a source star magnitude of I _s  < 21.4 mag. …”
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Microbiome response to cadmium and copper ingestion in the spider Steatoda grossa (Theridiidae): short-term and long-term effects of metal intoxication by G. Wilczek, M. Malicka, K. Kasperkiewicz, J. Łukasiak, C. A. Panek, J. Strzelczyk

“…The highest concentration of the metals was recorded in individuals after long-term exposure (with levels exceeding those of the control by 30 times for Cd and 5 times for Cu). The presence of metals in the food had a significant effect on the qualitative and quantitative structure of the microbiome, particularly in individuals exposed to contaminated food for the short term. …”
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Strong-weak dual interface engineered electrocatalyst for large current density hydrogen evolution reaction by Shaorou Ke, Ruiyu Mi, Xin Min, Xinyu Zhu, Congyi Wu, Xin Li, Bozhi Yang, Xiaowen Wu, Yangai Liu, Zhaohui Huang, Minghao Fang

“…As a result, the tailored catalyst has a 529.3 mV overpotential at 1000 mA cm−2 in 0.5 M H2SO4, 0.69 times less than commercial Pt/C. It also possesses 8.8 times the mass activity of commercial Pt/C and maintains a low overpotential after 2000 cyclic voltammetry cycles, suggesting high activity and stability. …”
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Study on Dynamic Characteristics of Deep Siltstone under High Static Stress and Frequent Dynamic Disturbance by Lu-ping Cheng, Chun Wang, Li-zhong Tang, Cheng Wang, Zhu-qiang Xiong, Shi-ming Wei, Yuan Chen, Tao Liu, Yong-heng Wei

“…The strain rate rises in a linear trend with the increasing times of dynamic disturbance, but the value of the strain rate is approximately constant in the process of one impact. …”
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Alteration of Mastication Force via Intraoral Closed-Loop Electrical Stimulation by Junxiang Zheng, Bing Jiang, Saurabh Biswas, Su Young Lee, Erin Ealba Bumann, Teresa E. Lever, Jeonghee Kim, Hangue Park

“…Their mastication forces were recorded ten times per condition. The recorded mastication force profile showed that mastication force was higher with the harder food. …”
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Influence of multi-point laser shock peening process on surficial mechanical properties in gear steels by XUE Cheng, LEI Duncai, YAN Xueyuan, ZANG Shunlai, DONG Hongtao, YOU Zhiwei

“…The effects of laser energy and impact times on the residual stress and micro-hardness of gear steel are experimentally investigated. …”
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EFFECTS OF PRENATAL YOGA ON THE ANXIETY OF PREGNANT WOMEN BEFORE BIRTH by Anggraini Dyah Setiyarini, Ellatyas Rahmawati Tejo Putri, Dwi Margareta Andini, Erna Rahmawati

“…Stress during pregnancy will affect the growth and development of the fetus. Anxiety is three times more likely to increase fear of childbirth and 1.7 times more likely to require a cesarean section. …”
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Enhanced Hydrothermal Depolymerization with Fe/Ni Loaded C Catalysts for Improving Anaerobic Digestion Performance of Corn Stover by Xitong Wang, Chenyang Zhu, Hairong Yuan, Xiujin Li

“…Meanwhile, the DC group produced 4.7 times more reducing sugar (RS), and a 3.4 times increase in total volatile fatty acids (VFAs) as compared to the control. …”
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Dynamic Analysis of the Scraper Conveyor under Abnormal Operating Conditions Based on the Vibration and Speed Characteristics by Shoubo Jiang, Weijian Ren, Qinghua Mao, Qingliang Zeng, Pengfei Yu, Kuidong Gao, Liang Wang

“…Results show that the longitudinal velocity of the link dramatically changes, the contact force increases by 5.4 times, and the link vibrates under impact loads. …”
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IMPROVING THE CHEMICAL PROPERTIES OF ACIDIC SOIL WITH AFFORDABLE LIME APPLICATION FOR INCREASING POTATO GROWTH AND YIELDS IN SEDIE DISTRICT, NORTHWESTERN ETHIOPIA by S. A. Yenesew

“…Each experimental plot had gross and net sizes of 2.1 m &times; 4.5 m (9.45 m&sup2;) and 1.5 m &times; 3 m (4.5 m&sup2;), respectively. …”
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Semavi Dinlerin Ortak Ahlak Değerleri ya da Evrensel Değerler by Halil İbrahim Bulut

“…Bu çerçevede doğru sözlü olmak, adaletli davranmak, iyilik yapmak, cana kıymamak, kul hakkı yememek gibi hususların insanlığın üzerinde ittifak ettiği ortak değerlerden olduğu anlaşılmaktadır.p.p1 {margin: 0.0px 0.0px 0.0px 2.0px; line-height: 8.1px; font: 8.0px 'Times New Roman'; color: #171717}p.p2 {margin: 0.0px 0.0px 0.0px 1.9px; text-align: justify; font: 8.0px 'Times New Roman'; color: #171717}span.s1 {letter-spacing: 0.1px}span.s2 {letter-spacing: 1.6px}span.s3 {letter-spacing: 0.7px}span.s4 {letter-spacing: 1.0px}span.s5 {letter-spacing: 1.1px}span.s6 {letter-spacing: 1.4px}span.s7 {letter-spacing: 0.3px}span.s8 {letter-spacing: 0.4px}span.s9 {letter-spacing: 1.5px}span.s10 {letter-spacing: 2.3px}span.s11 {letter-spacing: 2.4px}span.s12 {letter-spacing: 1.2px}span.s13 {letter-spacing: 1.9px}span.s14 {letter-spacing: 0.8px}…”
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Study on Deformation Law of Deep Foundation Pit with the Top-Down Method and Its Influence on Adjacent Subway Tunnel by Yue Gui, Zhenxing Zhao, Xiaqiang Qin, Jianfei Wang

“…The maximum distortion between the diaphragm wall and the column is less than 1/500 of the limit range proposed by Bjerrum. (3) The impact range caused by excavation is about 3.8 times the maximum excavation depth. The ground settlement around the foundation pit is groove type, and the maximum settlement point is located at 2.7 times the maximum excavation depth. (4) The excavation of the foundation pit leads to the maximum vertical settlement of 2 mm and maximum horizontal displacement of 5.2 mm in the subway tunnel; the maximum change of axial force and bending moment are 8.8 kN (the vertical direction) and 6.4 kN·m/m (the horizontal direction), respectively.…”
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Effects of Feeding Frequency for Nile Tilapia Fingerlings (Oreochromis niloticus) by Aldo Felipe Fava, Gildete de Souza Bezerra, Dacley Hertes Neu, Fabio Bittencourt, Altevir Signor, Kerolay Valadão Carvalho, Ricacio Luan Marques Gomes, Wilson Rogério Boscolo

“…In conclusion, fingerlings fed 5 to 6 times a day have better zootechnical and partial recipes.…”
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Pneumothorax, Pneumomediastinum, and Cervical and Facial Massive Emphysema Secondary to Colonoscopy: A Rare Complication of Colonoscopy by Ruben Daniel Perez Lopez, Julian Vargas Flores, Lenin de Jesus Orbe Garibay, Hugo Fernando Narvaez Gonzalez

“…The incidence of perforation is 0.03%–0.65% in diagnostic colonoscopy; however, the incidence can be up to 10 times higher in therapeutic interventions, such as polypectomies, increasing the risk of complications up to 0.07–2.1%. …”
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Evaluation on the Quasi‐Realistic Ionospheric Prediction Using an Ensemble Kalman Filter Data Assimilation Algorithm by Jianhui He, Xinan Yue, Huijun Le, Zhipeng Ren, Weixing Wan

“…Furthermore, the Thermosphere, Ionosphere, Mesosphere Energetics and Dynamics/Global Ultraviolet Imager (TIMED/GUVI) [O/N2] observations are used to validate the predicted thermosphere [O/N2]. …”
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Insecticide-treated nets utilization and influencing factors on middle school students in Southeast Nigeria. A cross-sectional study by Egbobe JohnPaul Otuomasiri, Magnus Michael Sichalwe, Ezaka Ephraim Ibeabuchi

“…Participants aged 15–19 were 2.258 times more likely to use ITNs than those aged 20–24. …”
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A longitudinal bottom-up analysis of staff travel patterns (2018–2023) at a research-intensive university hospital by N. Gebhardt, O. A. Kern, L. Schwaab, H.-C. Friederich, C. Nikendei

“…On average, medical professors emitted 24 times as much GHG as regular physicians per person, and 10 times as much as scientific research personnel. …”
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Effects of nonspecific resistance in barley genotypes obtained by cell selection by O. N. Shupletsova, S. Yu. Ogorodnikova, Ya. I. Nazarova

“…Against stressful soil backgrounds, regenerative lines induced on in vitro media with cadmium or aluminum were observed to have a low manifestation of oxidative stress symptoms, tested by the intensity of lipid peroxidation and the content of photosynthetic pigments in the leaves, which provided these genotypes with higher seed productivity (1.5–3.6 times in the number of grains, and 1.5– 3.0 times in the grain weight per plant) and adaptive advantages compared to the original genotype and regenerants induced on an in vitro medium with water deficiency. …”
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Does medical school research productivity predict a resident’s research productivity during residency? by Scott Kohlert, Laura Zuccaro, Laurie McLean, Kristian Macdonald

“…The odds of publishing during residency was 5.85 times higher (95% CI 2.69-12.71) if a resident published prior to residency (p < 0.0001). …”
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