مطالعه فیلوژنی مولکولی و ساختار پروتئین matk در سوسن چلچراغ (Lilium ledebourii [Baker] Boiss) by مرتضی شیخ اسدی, روح انگیز نادری, محسن کافی, محمد رضا فتاحی مقدم, علیرضا سلامی

“…بعد از تایید کیفیت و کمیت DNA، توالی‌یابی بصورت Real-Time (SMRT) با استفاده از پلتفرم نسل جدید PacBio انجام و توالی کامل ژن matK با استفاده از ابزراهای بیوانفورماتیک استخراج و در پایگاه اطلاعات ژنی NCBI به شماره دسترسی MN557236 ثبت شد. …”
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Reproductive hormone profiles and gametogenesis in female of giant gouramy (Osphronemus gouramy) by Gratiana E. Wijayanti, . Soeminto, Sorta B.I. Simanjuntak

“…Hormone levels were measured by using ELISA method with kit of REF30-407 for gonadotropin, REF30-431 for estradiol and REF30-406 for progesterone, respectively.  On the same time, ovarian were taken from fish group B. Ovarian were weighted to examine gonado somatic index (GSI), and they were then be fixative by NBF solution, processed to histology using paraffin, and stained with haematoxyline-eosin.   …”
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Beyond Dermatological Findings: Multisystem Involvement in Prolidase Deficiency by Ezgi Yalcin Gungoren, Zeynep Meric, Asena Pinar Sefer, Asuman Deveci Ozkan, Salim Can, Royala Babayeva, Nurhan Kasap, Ercan Nain, Esra Ozek Yucel, Ayca Kiykim, Sevgi Bilgic-Eltan, Ayse Deniz Yucelten, Elif Karakoc-Aydiner, Ahmet Ozen, Safa Baris

“…In patients P1 and P2, the percentages of naive T cells and recent thymic emigrants were reduced, suggesting combined immune deficiency at the time of diagnosis. CD19+ B cells were also low in P1 and P2. …”
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Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction by Montserrat Guadalupe Garza-Reyes, Mónica Daniela Mora-Ruíz, Luis Chávez-Sánchez, Alejandra Madrid-Miller, Alberto Jose Cabrera-Quintero, José Luis Maravillas-Montero, Alejandro Zentella-Dehesa, Luis Moreno-Ruíz, Selene Pastor-Salgado, Erick Ramírez-Arias, Nataly Pérez-Velázquez, Adriana Karina Chávez-Rueda, Francisco Blanco-Favela, Wendy Guadalupe Vazquez-Gonzalez, Alicia Contreras-Rodríguez

“…Here, we describe for the first time the effect of IL-17 in the migration and activation of monocyte subsets in patients during ST-segment elevation myocardial infarction (STEMI) and post-STEMI. …”
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Pien Tze Huang Attenuates Neuro-inflammatory Injury in BV2 Microglial Cells Induced by Lipopolysaccharide via Inhibition of TLR4/MAPK Signaling Pathway by Zhenwei HUANG, Qing ZHANG, Lili HUANG, Xiaoqin ZHANG, Mingqing HUANG

“…And then the mRNA expression of IL-1β, IL-6 and TNF-α were determined using real time-qPCR. BV2 microglial cells were seeded at a density of 1.6×10⁵cells/mL in 6-well plate. …”
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Adherence to a digital therapeutic mediates the relationship between momentary self-regulation and health risk behaviors by Enzo G. Plaitano, Enzo G. Plaitano, Daniel McNeish, Sophia M. Bartels, Sophia M. Bartels, Kathleen Bell, Jesse Dallery, Michael Grabinski, Michaela Kiernan, Hannah A. Lavoie, Hannah A. Lavoie, Shea M. Lemley, Michael R. Lowe, David P. MacKinnon, Stephen A. Metcalf, Stephen A. Metcalf, Lisa Onken, Judith J. Prochaska, Cady Lauren Sand, Cady Lauren Sand, Emily A. Scherer, Luke E. Stoeckel, Haiyi Xie, Lisa A. Marsch

“…Self-regulation is one fundamental behavior change mechanism often incorporated within digital therapeutics as it varies momentarily across time and contexts and may play a causal role in improving these health behaviors. …”
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Architecture et réfection des aqueducs d’Orléans/Cenabum (Loiret) by Julien Courtois, Mathilde Noël, Franck Verneau

“…The radiocarbon analyses carried out on certain pieces of wood suggest a date for the felling of the wood during the autumn or winter of 345-346, thus confirming that this section of aqueduct was in use in the middle of the 4th century and that the route of the aqueduct and the location of the surface manholes were known at that time.…”
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Phosphorus-solubilizing fungi promote the growth of Fritillaria taipaiensis P. Y. Li by regulating physiological and biochemical reactions and protecting enzyme system–related gene... by Yueheng Wang, Lin Yuan, Lin Yuan, Yuhan Wang, Jiaqi Lang, Mingyan Ye, Qingqiu Liu, Qiang Ma, Nong Zhou

“…The expression levels of FtSOD, FtPOD, and FtCAT in the S5 group were the highest, which were 8.67, 7.65, and 6.08 times of those in the CK group, respectively.ConclusionVarious combinations of phosphorus-solubilizing fungi exhibit differential capacities to enhance plant growth indices (including leaf area, plant height, and stem diameter), promote the accumulation of photosynthetic pigments, regulate osmotic pressure, and elevate antioxidant activity. …”
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Multiple large language models versus experienced physicians in diagnosing challenging cases with gastrointestinal symptoms by Xintian Yang, Tongxin Li, Han Wang, Rongchun Zhang, Zhi Ni, Na Liu, Huihong Zhai, Jianghai Zhao, Fandong Meng, Zhongyin Zhou, Shanhong Tang, Limei Wang, Xiangping Wang, Hui Luo, Gui Ren, Linhui Zhang, Xiaoyu Kang, Jun Wang, Ning Bo, Xiaoning Yang, Weijie Xue, Xiaoyin Zhang, Ning Chen, Rui Guo, Baiwen Li, Yajun Li, Yaling Liu, Tiantian Zhang, Shuhui Liang, Yong Lv, Yongzhan Nie, Daiming Fan, Lina Zhao, Yanglin Pan

“…The study highlights that advanced LLMs may assist gastroenterologists with instructive, time-saving, and cost-effective diagnostic scopes in challenging cases.…”
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Solar Energetic Particle Events Detected in the Housekeeping Data of the European Space Agency's Spacecraft Flotilla in the Solar System by Beatriz Sánchez‐Cano, Olivier Witasse, Elise W. Knutsen, Dikshita Meggi, Shayla Viet, Mark Lester, Robert F. Wimmer‐Schweingruber, Marco Pinto, Richard Moissl, Johannes Benkhoff, Hermann Opgenoorth, Uli Auster, Jos deBrujine, Peter Collins, Guido DeMarchi, David Fischer, Yoshifumi Futaana, James Godfrey, Daniel Heyner, Mats Holmstrom, Andrew Johnstone, Simon Joyce, Daniel Lakey, Santa Martinez, David Milligan, Elsa Montagnon, Daniel Müller, Stefano A. Livi, Timo Prusti, Jim Raines, Ingo Richter, Daniel Schmid, Peter Schmitz, Håkan Svedhem, Matt G. G. T. Taylor, Elena Tremolizzo, Dimitri Titov, Colin Wilson, Simon Wood, Joe Zender

“…These counters typically have a sudden large increase in a short time in their error counts that generally match the arrival of energetic particles to the spacecraft. …”
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油脂对植物基冰淇淋乳液性质及产品品质的影响 "Effect of vegetable oil on the properties of plant-based ice cream emulsion and the quality of products" by 张贵金1，范军营2，尹永智2，逯彩云2，张晖1， 王兴国1，吴港城1 ZHANG Guijin1, FAN Junying2, YIN Yongzhi2, LU Caiyun2, ZHANG Hui1, WANG Xingguo1, WU Gangcheng1"

“…The ice cream emulsion prepared with hydrogenated coconut oil and modified soy protein isolate had the lowest interfacial protein content, at 10.48 mg/m2, the highest degree of fat partial aggregation, at 68.89%, and the expansion rate, melting rate and melting lag time of the ice cream were 66.15%, 7.12%, and 212 s, respectively. …”
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The 0ν2β-decay CROSS experiment: preliminary results and prospects by The CROSS collaboration, I. C. Bandac, A. S. Barabash, L. Bergé, M. Brière, C. Bourgeois, P. Carniti, M. Chapellier, M. de Combarieu, I. Dafinei, F. A. Danevich, N. Dosme, D. Doullet, L. Dumoulin, F. Ferri, A. Giuliani, C. Gotti, P. Gras, E. Guerard, A. Ianni, H. Khalife, S. I. Konovalov, E. Legay, P. Loaiza, P. de Marcillac, S. Marnieros, C. A. Marrache-Kikuchi, C. Nones, V. Novati, E. Olivieri, C. Oriol, G. Pessina, D. V. Poda, T. Redon, V. I. Tretyak, V. I. Umatov, M. M. Zarytsky, A. S. Zolotarova

“…Its experimental investigation is the only viable method that can establish the Majorana nature of neutrinos, providing at the same time a sensitive inclusive test of lepton number violation. …”
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GATA2 mutated allele specific expression is associated with a hyporesponsive state of HSC in GATA2 deficiency syndrome by Laetitia Largeaud, Vincent Fregona, Laura A. Jamrog, Camille Hamelle, Stéphanie Dufrechou, Naïs Prade, Esmaa Sellam, Pauline Enfedaque, Manon Bayet, Sylvie Hébrard, Mathieu Bouttier, Christine Didier, Bastien Gerby, Eric Delabesse, Marlène Pasquet, Cyril Broccardo

“…This population showed hyporesponsiveness, accumulated over time, and exhibited allele-specific expression (ASE) favoring the mutated Gata2 allele, also observed in GATA2 mutated patients. …”
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Understanding the scale and nature of avoidable healthcare-associated harm for prisoners in England: protocol for a retrospective cross-sectional study by Andrew Carson-Stevens, Maria Panagioti, Adrian Edwards, Jenny Shaw, Stephen Campbell, Carl de Wet, Kate Davies, Anthony Avery, Stuart Hellard, Melanie Jordan, Caroline Sanders, Isobel Joy McFadzean, Jane Senior, Darren M. Ashcroft, Caroline Stevenson, Tim Millar, Saied Ibrahim, Thomas Hewson, Sandra Flynn, Thomas Purchase, Florian Walter, Sioned Gwyn, Richard N. Keers, Ellie Thompson, Verity Wainwright

“…Univariable and multivariable analyses will be conducted to identify factors associated with avoidable harm.Ethics and dissemination The decision regarding participation by prisons within the study will be voluntary, and their consent to participate may be withdrawn at any time. We will not seek individual patient consent for the retrospective case note review of their records, but if patients respond to publicity about the project and inform us that they do not wish their records to be included, we will adhere to their wishes. …”
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FGF21 ameliorates diabetic nephropathy through CDK1-dependently regulating the cell cycle by Yudie Zhang, Yudie Zhang, Yudie Zhang, Yudie Zhang, Yudie Zhang, Fan Wang, Fan Wang, Fan Wang, Fan Wang, Chongyang Zhang, Chongyang Zhang, Chongyang Zhang, Chongyang Zhang, Fan Yao, Fan Yao, Fan Yao, Fan Yao, Bin Zhang, Bin Zhang, Bin Zhang, Bin Zhang, Yongping Zhang, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun

“…To investigate the mechanism of action of FGF21 in the treatment of glycolytic kidney, transcriptome sequencing of renal tissues and KEGG pathway enrichment analysis of differential genes were performed.ResultsThe study’s findings demonstrated that FGF21 intervention increased clotting time, decreased oxidative stress and inflammation, and avoided thrombosis in addition to considerably improving glomerular filtration damage. …”
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Assessment of platelet-to-white blood cell ratio on short-term mortality events in patients hospitalized with acute decompensated heart failure: evidence from a cohort study from J... by Xin Huang, Xin Huang, Xin Huang, Xin Huang, Maobin Kuang, Maobin Kuang, Maobin Kuang, Maobin Kuang, Jiajun Qiu, Jiajun Qiu, Jiajun Qiu, Jiajun Qiu, Chao Wang, Chao Wang, Chao Wang, Chao Wang, Guotai Sheng, Guotai Sheng, Yang Zou, Guobo Xie

“…Subgroup analysis showed that compared to subjects with reduced or moderately reduced ejection fraction, ADHF patients with preserved ejection fraction had a lower risk of short-term mortality associated with PWR (HR:0.99 vs. 0.98 vs. 0.87, P for interaction = 0.0067).ConclusionThis study reveals, for the first time, a negative correlation between the inflammatory marker PWR and all-cause mortality within 30 days of hospitalization in ADHF patients. …”
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The concerted actions of microRNA-29a and interferon-β modulate complete Freund's adjuvant-induced inflammatory pain by regulating the expression of type 1 interferon receptor, int... by Chien-Cheng Liu, Kuo-Chuan Hung, Yu-Yu Li, Eagle Yi-Kung Huang, Chin-Chen Chu, Lok-Hi Chow, Ping-Heng Tan

“…Results: Our results demonstrated elevated miR-29a expression (CFA 3 days: mean difference [95% confidence interval, CI]: 0.860 [0.657–1.062]; CFA 5 days: mean difference [95% CI]: 1.120 [0.917–1.322], P<0.001, n=6) and decreased IFNR1 expression (CFA 3 days: mean difference [95% CI]: −0.300 [−0.470 to −0.130]; CFA 5 days: mean difference [95% CI]: −0.330 [−0.515 to −0.145], P=0.004, n=6) from Days 3–5 post-CFA induction, with IFN-ß expression showing a significant increase from Day 2 (F [3.30, 16.5]=34.3 for factor time, P≤0.01, n=6). Treatment with an miR-29a inhibitor alleviated CFA-induced mechanical allodynia and thermal hyperalgesia by Day 5 (P<0.001, n=9), concomitant with upregulation of IFNR1 and ISG15 expression, and downregulation of p-ERK (IFNR1; CFA 5 days + miR-29a inhibitor vs CFA 5 days; mean difference [95% CI]: 30.00 [20.31–39.69]; ISG15 conjugates; CFA 5 days + miR-29a inhibitor vs CFA 5 days, mean difference [95% CI]: 1.000 [0.9144–1.086]; free ISG15, mean difference [95% CI]: 2.402 [2.171–2.633]; p-ERK; CFA 5 days + miR-29a inhibitor vs CFA 5 days, mean difference [95% CI]: −32.00 [−34.10 to −29.90], P<0.001, n=9). …”
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Studying the Oncolytic Activity of <i>Streptococcus pyogenes</i> Strains Against Hepatoma, Glioma, and Pancreatic Cancer <i>In Vitro</i> and <i>In Vivo</i> by Anna N. Tsapieva, Alexander N. Chernov, Nadezhda V. Duplik, Anastasiya O. Morozova, Tatiana A. Filatenkova, Mariia A. Suvorova, Elena Egidarova, Elvira S. Galimova, Kseniya Bogatireva, Alexander N. Suvorov

“…Methods: The <i>in vitro</i> oncolytic cytotoxic activity of GAS strains was studied against human glioma U251, pancreatic cancer PANC02, murine hepatoma 22a, and normal skin fibroblast cells using the MTT assay and the real-time xCELLigence system. A syngeneic mouse model of hepatoma and pancreatic cancer was used to evaluate the <i>in vivo</i> oncolytic effect of GAS strains. …”
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Comparison of outcome and toxicity of postoperative intensity‐modulated radiation therapy with two‐dimensional radiotherapy in patients with soft tissue sarcoma of extremities and... by Jianyang Wang, Yongwen Song, Xinfan Liu, Jing Jin, Weihu Wang, Zihao Yu, Yueping Liu, Ning Li, Hui Fang, Hua Ren, Yuan Tang, Yu Tang, Bo Chen, Ningning Lu, Shunan Qi, Shulian Wang, Yexiong Li

“…Results With a median follow‐up time of 58.1 months, 30 local recurrences, 66 distant metastases, and 40 deaths occurred. …”
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Resultados a corto y largo plazo tras trasplante cardíaco en pacientes con cardiopatías congénitas by Marta Molina, Elena Roselló, Manel Tauron, Juan F. Tabilo, Constanza Fernandez, Carla Gotsens, Exzequiel Pueblas, José Montiel, Sandra Casellas, Angela Irabien, Laura Corominas, Laura López, Sonia Mirabet, Antonino Ginel

“…There were no significant differences in extracorporeal circulation time, reoperation for bleeding, or hospital stay. …”
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