Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration by Shuangpeng Jiang, Guangzhao Tian, Xu Li, Zhen Yang, Fuxin Wang, Zhuang Tian, Bo Huang, Fu Wei, Kangkang Zha, Zhiqiang Sun, Xiang Sui, Shuyun Liu, Weimin Guo, Quanyi Guo

“…However, recent evidence has shown that the stem cell secretome plays an important role in biological processes such as the immune response, inflammation regulation, and drug delivery. At the same time, the stem cell secretome can effectively mediate the process of tissue regeneration. …”
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Pearls on a String: Dark and Bright Galaxies on a Strikingly Straight and Narrow Filament by M. Arabsalmani, S. Roychowdhury, B. Schneider, V. Springel, E. Le Floc’h, F. Bournaud, A. Burkert, J.-C. Cuillandre, P.-A. Duc, E. Emsellem, D. Galárraga-Espinosa, E. Pian, F. Renaud, M. A. Zwaan

“…The presence of such gas clouds around the filament spines is predicted by simulations, but this is the first time that the existence of such clouds in a filament is observationally confirmed.…”
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Current situation of central nervous system tumour survivors in a spanish hospital by Ivonne Marcela Rincón-Mantilla, Blanca Herrero, Elena Herranz Valero, Fernando Robles-Bermejo, Alba Herrera-Olivares, Felisa Vázquez-Gómez, Álvaro Lassaletta

“…Results: The mean current age of CNS tumour survivors was 20 years (range, 12–34). The median time since diagnosis was 13 years (range, 10–26). …”
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Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood by Olga D. Boer, Thea Wiker, Shervin H. Bukhari, Rikka Kjelkenes, Clara M.F. Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T. Westlye, Ingmar H.A. Franken, Hanan El Marroun, Rene J. Huster, Christian K. Tamnes

“…Linear regressions were conducted using bootstrap resampling to explore associations between ERN/Pe peak amplitudes and latencies, stop accuracy, stop-signal reaction time (SSRT), and post-error slowing, as well as self-reported substance-related risks and problems and externalizing problems. …”
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Le travail des peaux et du cuir durant le Haut-Empire à Bordeaux/Burdigala (Gironde), d’après les vestiges mis au jour sur le site de la rue Jean-Fleuret by Vanessa Elizagoyen, Christophe Sireix, Gisèle Allenet de Ribemont, Laurence Benquet, Philippe Borgard, Emilie Claud, Katleen Couchez, Marie-France Dietsch-Sellami, Stéphan Dubernet, Véronique Guitton, Jérôme Hénique, Yannick Le Digol, Martine Leguilloux, Sébastien Lepetz, Fabrice Leroy, Hélène Martin, Alain Queffelec, Stéphanie Raux, Nima Saedlou, Farid Sellami, Laure Simon, Serge Vigier

“…The craft activity identified at Jean-Fleuret ceased around 150/160, at which time the area appears to have been put under cultivation, perhaps until the end of the 2nd century. …”
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Relapse-free survival is progressively shortened in a subset of Black patients with immune-mediated TTP treated in the rituximab era by Ayotola Fatola, Michael D. Evans, Jenna Brown, Elizabeth Davis, Andrew Johnson, Ana G. Antun, Andrew M. Farland, Ryan Woods, Ara Metjian, Yara A. Park, Gustaaf de Ridder, Briana Gibson, Raj S. Kasthuri, Darla K. Liles, Susan Eubanks, Frank Akwaa, Todd Clover, Lisa Baumann Kreuziger, J. Evan Sadler, Meera Sridharan, Ronald S. Go, Keith R. McCrae, Harsh Vardhan Upreti, Ming Y. Lim, Nicole K. Kocher, Radhika Gangaraju, X. Long Zheng, Jay S. Raval, Camila Masias, Spero R. Cataland, Marshall Mazepa, Shruti Chaturvedi

“…Separately, we evaluated overall RFS (composite of time to clinical relapse, ADAMTS13 relapse, or preemptive rituximab) in a prospective iTTP cohort from the Johns Hopkins University and the University of Minnesota. …”
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A Meta-analysis of Sanyrene in preventing radiation dermatitis of head and neck tumor (赛肤润预防头颈部肿瘤放射性皮炎的Meta分析) by ZHENG Ya (郑雅), ZENG Guqing (曾谷清), PENG Lingying (彭玲英), NI Xiaoyan (倪晓燕), WANG Aoyi (王傲一), PAN Rongjia (潘荣佳), NIAN Fang (年芳)

“…The intervention group used Sanyrene, and the control group used other preventive medications or placebos or conventional methods (such as flushing with water). The search time limit is from the establishment of the database to December 31, 2019. …”
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MSCs Contribute to the Conversion of Ly6Chigh Monocytes into Ly6Clow Subsets under AMI by Wenbin Lu, Genshan Ma, Zulong Sheng, Qingjie Wang, Lijuan Chen, Junhua Qi, Ronghui Shi, Jingjing Ji, Zhenjun Ji, Qiming Dai

“…The expression of NR4A1 in Ly6Chigh/low monocytes was also significantly elevated at that time (1.81±0.46 vs. 0.43±0.09, p<0.001). Following AMI, the percentage of circulating Ly6Clow monocytes in C57BL/6CX3CR1-/- mice was significantly lower than that in C57BL/6 wild-type mice (4.36%±1.27% vs. 12.17%±3.81%, p<0.001). …”
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Challenges and enablers for scaling up interventions targeting non-communicable diseases: a qualitative study applying the Consolidated Framework for Implementation Research to 19... by Josefien van Olmen, Peter Delobelle, Meena Daivadanam, Hassan Haghparast-Bidgoli, Maria Lazo-Porras, J Jaime Miranda, Yuan Li, Rohina Joshi, Amanda G Thrift, Rajesh Vedanthan, Gina Agarwal, Mark D Huffman, Kerstin Klipstein-Grobusch, Naomi Levitt, Dike Ojji, Feng J He, Kamran Siddiqi, Pascal Geldsetzer, Puhong Zhang, Milena Soriano Marcolino, Lal B Rawal, Brian Oldenburg, Helena Teede, Josephine Birungi, Edwin Wouters, Abha Shrestha, Ari Probandari, Mayowa Owolabi, Vilma Irazola, Andrea Beratarrechea, Keiko Nakamura, Gindo Tampubolon, Zulma Ortiz, Violet Naanyu, Jaap Koot, Anusha Ramani-Chander, Stephen Sherwood, Monika Martens, Gade Waqa, Maria Eugenia Esandi, Sujarwoto Sujarwoto, Laura Antonietti, Jan-Walter De Neve, Sayoki G Mfinanga, Antonio Luiz Pinho Ribeiro

“…Generated themes were mapped systematically to four out of five domain categorisations of the Consolidated Framework for Implementation Research (CFIR); the innovation domain fell outside the scope of this study.Results Highlighted findings using CFIR are: (i) outer setting: influence of politics, lack of coordination between government departments and differing agendas towards NCDs hindered implementation while reliable and trustworthy government connections proved useful; (ii) inner setting: commitment of resources for implementation was a challenge while research capacity, work culture and trustworthy networks facilitated implementation; (iii) individuals: high-level stakeholder support and leadership was essential; (iv) process: extensive time and efforts required for stakeholder engagement towards local contextualisation was challenging, while collaborating, joint reflection, effective communication and adaptation facilitated. …”
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Xpert Bladder Cancer Detection in Emergency Setting Assessment (XESA Project): A Prospective, Single-centre Trial by Federica Sordelli, Antonio Desai, Filippo Dagnino, Roberto Contieri, Sofia Giuriolo, Marco Paciotti, Vittorio Fasulo, Stefano Mancon, Davide Maffei, Pier Paolo Avolio, Giorgio Da Rin, Federica Maura, Elena Vanni, Davide Federico, Piergiuseppe Colombo, Giovanni Lughezzani, Nicolò Maria Buffi, Paolo Casale, Alberto Saita, Massiomo Lazzeri, Rodolfo Hurle, Antonio Voza

“…We found that for patients visiting the emergency department because of blood in their urine, use of this test could save time and money over urine cell analysis (UCA) for ruling out or diagnosing bladder cancer. …”
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Improving Growth Performance, Biochemical Parameters and Reducing Mortality due to Ascites in Broilers by Propranolol Inclusion by Shahriar Saidian, Somaya Farahmand, Mokhtar Fathi, Salar Saifi

“…The levels of glutathione peroxidase, superoxide dismutase, and catalase enzymes were decreased in ascites-induced broiler chickens. At the same time, it decreased the level of serum malondialdehyde, aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase enzymes (P<0.05). …”
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CHARACTERISTICS OF CIRCADIAN BLOOD PRESSURE PROFILE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND THEIR ASSOCIATION WITH THYROID FUNCTION by Nataliia Kuz, Tetiana Solomenchuk

“…The following indicators have been determined: systolic BP (SBP) - daytime, nighttime, and average daily (24 hours) (SBPd, SBPn, and SBPav); diastolic BP (DBPd, DBPn, and DBPav); pulse BP (PBPd, PBPn, and PBPav); time index (TI) for SBPd, SBPn, and SBPav (SBPd TI, SBPn TI, and SBPav TI) and DBP (DBPd TI, DBPn TI, and DBPav TI); variability of SBPd, SBPn, and SBPav (SBPd var, SBPn var, and SBPav var) and DBP (DBPd var, DBPn var, and DBPav var); average daily index for SBP (SBP AvDI) and DBP (DBP AvDI); average daily heart rate (HRav). …”
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Accuracy of Established Prognostic Staging Systems for Cardiac Transthyretin Amyloidosis in the Tafamidis Era by Maximilian Leo Müller, MD, Sebastian Spethmann, MD, Daniel Messroghli, MD, Anna Brand, MD, Isabel Mattig, MD, Katrin Hahn, MD, Ulf Landmesser, MD, Bettina Heidecker, MD

“…Methods: A retrospective observational study following patients with ATTR-CA from initiation of tafamidis (baseline) to time of all-cause death was conducted. Patients were stratified according to the NAC and an adapted Mayo staging system incorporating high-sensitivity cardiac troponin T. …”
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Clinical observation of external application of compound Baiyu powder in treating cracked nipples during lactation period and related nursing management (复方白玉散外敷治疗哺乳期乳头皲裂临床疗效观察及护理)... by CHEN Shuangshuang (陈双双), WANG Yuan (王媛), YOU Tingli (游婷李), CHEN Juan (陈娟)

“…Results The total response rate was 97. 44%(38/39) in the group a, which was higher than 68. 42%(26/38) in group B and 40. 00% (16/40) in control group(P＜0. 05 respectively). A shorter time to pain relief and healing of cracked skin were observed in group A than those in group B and control group, respectively(P＜0. 01). …”
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Spotted fever group rickettsiae in black rats, pets, and humans in Zungarococha community, A rural area in the surroundings of Iquitos, Peru by Cusi Ferradas, Guillermo Salvatierra, David Payahuanca, Winnie Contreras, Andrés M. López-Pérez, Therangika A. Hangawatte, Diana León, Bruno M. Ghersi, Ricardo Gamboa, Katia Manzanares Villanueva, Viviana Pinedo-Cancino, Risa Pesapane, Gabriela Salmón-Mulanovich, Andrés G. Lescano, Janet Foley

“…We screened ectoparasites and black rat tissues by real-time-PCR (qPCR). Positive ectoparasites were further assessed by PCR and DNA amplicon sequencing. …”
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响应面优化氯化胆碱-丙三醇体系提取芝麻蛋白工艺条件 "Response surface optimization of the extraction process conditions for sesame protein using choline chloride-glycerol system"... by 曹培换1，张晨霞1，刘燕2，马宇翔1，刘华敏1，郑永战1，3 "CAO Peihuan1，ZHANG Chenxia1，LIU Yan2，MA Yuxiang1， LIU Huamin1，ZHENG Yongzhan1,3"

“…The results showed that the optimal conditions for extracting sesame protein were as follows: moisture content in DES 10%, solid-liquid mass ratio 1∶ 29.4, extraction temperature 59.0 ℃, extraction time 1 h, and stirring speed 750 r/min. Under these conditions, the extraction rate of sesame protein was (64.65 ±0.52)%, significantly lower than that of the alkali solution-acid precipitation method((74.19±1.79)%). …”
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Logistic Regression Model in a Machine Learning Application to Predict Elderly Kidney Transplant Recipients with Worse Renal Function One Year after Kidney Transplant: Elderly KTbo... by Ubiracé Fernando Elihimas Júnior, Jamila Pinho Couto, Wallace Pereira, Michel Pompeu Barros de Oliveira Sá, Eduardo Eriko Tenório de França, Filipe Carrilho Aguiar, Diogo Buarque Cordeiro Cabral, Saulo Barbosa Vasconcelos Alencar, Saulo José da Costa Feitosa, Thais Oliveira Claizoni dos Santos, Helen Conceição dos Santos Elihimas, Emilly Pereira Alves, Marcio José de Carvalho Lima, Frederico Castelo Branco Cavalcanti, Paulo Adriano Schwingel

“…We analysed medical records of KT recipients from January to December 2017, with a follow-up time of one year after KT. We used multivariable logistic regression to estimate odds ratios for elderly vs younger recipients, controlled for demographic, clinical, laboratory, data pre- and post-KT, and death. …”
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Modern theoretical-methodological and economic-legal problems of implementing the concept of sustainable development of tourism and recreation in Ukraine by Ion Dubovich, Alla Anishchenko, Nadia Yurkiv, Yuliia Volkovska, Rostyslav Matsko, Oleh Rozhkovych, Mariana-Nadiia Dubovich, Oksana Pylypiak

“…It is noted that tourism and recreation in Ukraine is an industry with great potential and prospects, but at the same time it is a complex and dynamic system that covers various regional, ecological, economic, organizational and other aspects.It is emphasized that Ukraine, due to its unique natural resources, rich historical heritage and socio-cultural values, has great potential in the field of tourism and recreation, which creates opportunities for its development throughout the year.It is found that in order to achieve effective results regarding the organization, functioning and development of tourism and recreation, a number of regulatory legal acts were adopted in Ukraine. …”
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Effect of Slit3 on kidney fibrosis in diabetic kidney disease rats by Huang Ming-fang, Dong Yang, Shadek-jiang Harinul, Gan Xin-yu, Shi Wen-li, Lu Chen

“…The reverse-transcription quantitative real-time polymerase chain reaction （RT-qPCR） was performed to detect mRNA levels of Slit3， α-smooth muscle actin （α-SMA）， and transforming growth factor-β1 （TGF-β1） in kidney tissues， and their protein levels were detected by Western blot. …”
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Antiedemic Effect of the Myosin Light Chain Kinase Inhibitor PIK7 in the Rat Model of Myocardial Ischemia Reperfusion Injury by Dmitry L. Sonin, Mikhail S. Medved, Asker Y. Khapchaev, Maria V. Sidorova, Marina E. Palkeeva, Olga A. Kazakova, Garry V. Papayan, Daniil A. Mochalov, Sarkis M. Minasyan, Ilya E. Anufriev, Daria V. Mukhametdinova, Natalia M. Paramonova, Ksenia M. Balabanova, Anastasia S. Lopatina, Ilia V. Aleksandrov, Natalya Yu. Semenova, Anna A. Kordyukova, Kirill V. Zaichenko, Vladimir P. Shirinsky, Michael M. Galagudza

“…The early no-reflow detected for the first time after 30 min ischemia in this model of myocardial infarction reduces the area accessible for PIK7. …”
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