Comparison of the Insertion Conditions and Haemodynamic Changes during I-Gel Insertion using Propofol, Ketamine-Propofol (Ketofol) and Thiopentone Intravenous Induction Agents: An... by Pooja Arpapan Shah, Aashi Nilesh Surti, Anupapama Kumari, Dinesh K Chauhan, Sara Mary Thomas

“…Complete jaw relaxation and mouth opening were better in the ketofol group than in the propofol group (p-value: 0.003) and were significantly lower in the thiopentone group. Induction time was faster in the ketofol group than in the other groups. …”
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Cement-within-cement technique in revision reverse total shoulder arthroplasty: complications, reoperations, and revision rates at 5-year mean follow-up by Rodrigo de Marinis, MD, John W. Sperling, Jr., Erick M. Marigi, MD, Ausberto Velasquez Garcia, MD, Eric R. Wagner, MD, Joaquin Sanchez-Sotelo, MD, PhD

“…Although a low rate of humeral component loosening was observed, higher rates of complications and re-revision surgery were observed over time secondary to aseptic glenoid component loosening and instability, which are not directly related to CwC technique but to revision surgery in general.…”
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Risk of Coronary Heart Disease among HIV-Infected Patients: A Multicenter Study in Brazil by Sandra C. Fuchs, Paulo R. Alencastro, Maria Letícia R. Ikeda, Nêmora T. Barcellos, Fernando H. Wolff, Ajácio B. M. Brandão, Ricardo A. A. Ximenes, Demócrito de B. Miranda-Filho, Heloísa Ramos Lacerda, Maria de Fátima P. M. de Albuquerque, Ulisses Ramos Montarroyos, Max W. Nery, Marilia D. Turchi

“…The use of antiretroviral agents and time since HIV diagnosis were not risk factors for coronary artery disease in 10 years. …”
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Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia by Rong Lin, Rong Lin, XiaoYing Weng, XiaoYing Weng, Liang Lin, Liang Lin, XuYang Hu, XuYang Hu, ZhiYan Liu, ZhiYan Liu, Jing Zheng, Jing Zheng, FenFang Shen, FenFang Shen, Rui Li, Rui Li

“…Clinical validation was conducted via real-time quantitative polymerase chain reaction (RT-qPCR), immunofluorescence, and Western blot.ResultsFour genes [solute carrier family 25 member 5 (SLC25A5), acyl-CoA synthetase family member 2 (ACSF2), mitochondrial fission factor (MFF), and phorbol-12-myristate-13-acetate–induced protein 1 (PMAIP1)] were identified as biomarkers distinguishing PE from normal controls. …”
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The efficacy of sinustrabeculectomy in the modern clinical practice by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy, A.Ya. Vuks

“…The analysis of postoperative intraocular pressure (IOP) changes over time was performed using statistical methods. </p> <p> <b>Results</b>: the "complete success" of surgical operation achieved in 305 (68.9%) cases was associated with a significant and long-lasting decrease (at least for two years) in IOP values. …”
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Modulation of local immunity by the vaginal microbiome is associated with triggering spontaneous preterm birth by Yijia Liang, Yijia Liang, Yijia Liang, Changying Zhao, Yan Wen, Dashuang Sheng, Tiantian Wei, Tianqi Hu, Junhui Dai, Guoping Zhao, Guoping Zhao, Guoping Zhao, Sijie Yang, Sijie Yang, Qinghua Wang, Lei Zhang, Lei Zhang

“…Microorganisms affected the occurrence of preterm birth by modulating immune factor levels, with time-specific mediation roles observed. Lactobacillus crispatus demonstrated potential in protecting against preterm birth by modulating vaginal immune status.…”
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RETRACTED ARTICLE: Extracorporeal membrane oxygenation support for SARS-CoV-2: a multi-centered, prospective, observational study in critically ill 92 patients in Saudi Arabia by Saad Alhumaid, Abbas Al Mutair, Header A. Alghazal, Ali J. Alhaddad, Hassan Al-Helal, Sadiq A. Al Salman, Jalal Alali, Sana Almahmoud, Zulfa M. Alhejy, Ahmad A. Albagshi, Javed Muhammad, Amjad Khan, Tarek Sulaiman, Maha Al-Mozaini, Kuldeep Dhama, Jaffar A. Al-Tawfiq, Ali A. Rabaan

“…Also, there was a high number of patients with septic shock (19.6%) and multiple organ failure (10.9%); and more complications occurred at any time during hospitalization [pneumothorax (5% vs 29.3%, p = 0.000), bleeding requiring blood transfusion (7.1% vs 38%, p = 0.000), pulmonary embolism (6.4% vs 15.2%, p = 0.016), and gastrointestinal bleeding (3.3% vs 8.7%, p = 0.017)] in the ECMO group. …”
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Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans by Benjamin R Kop, Yazan Shamli Oghli, Talyta C Grippe, Tulika Nandi, Judith Lefkes, Sjoerd W Meijer, Soha Farboud, Marwan Engels, Michelle Hamani, Melissa Null, Angela Radetz, Umair Hassan, Ghazaleh Darmani, Andrey Chetverikov, Hanneke EM den Ouden, Til Ole Bergmann, Robert Chen, Lennart Verhagen

“…Across multiple studies, one promising protocol, pulsed at 1000 Hz, has consistently resulted in motor cortical inhibition in humans (Fomenko et al., 2020). At the same time, a parallel research line has highlighted the potentially confounding influence of peripheral auditory stimulation arising from TUS pulsing at audible frequencies. …”
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Characterisation of the effects of the chemotherapeutic agent paclitaxel on neuropathic pain-related behaviour, anxiodepressive behaviour, cognition, and the endocannabinoid system... by Chiara Di Marino, Chiara Di Marino, Chiara Di Marino, Chiara Di Marino, Álvaro Llorente-Berzal, Álvaro Llorente-Berzal, Álvaro Llorente-Berzal, Alba M. Diego, Alba M. Diego, Alba M. Diego, Ariadni Bella, Ariadni Bella, Ariadni Bella, Laura Boullon, Laura Boullon, Laura Boullon, Esther Berrocoso, Esther Berrocoso, Esther Berrocoso, Michelle Roche, Michelle Roche, Michelle Roche, David P. Finn, David P. Finn, David P. Finn

“…After the induction of the model, pain-related behaviours were assessed using von Frey, Acetone Drop and Hargreaves’ tests, Novel Object Recognition and T-Maze Spontaneous Alternation tests were used for cognition-related behaviours, Elevated Plus Maze, Open Field, and Light Dark Box tests were used to assess anxiety-related behaviours, and Sucrose Preference, Sucrose Splash, and Forced Swim tests for depression-related behaviours. At each time point analysed, animals treated with PTX exhibited mechanical and cold hypersensitivity, with females displaying lower hind paw withdrawal thresholds to mechanical stimulation than males. …”
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Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

“…Next, we use five promising biomarkers for relative real‐time polymerase chain reaction (PCR) quantification: TLR4, IL8, NRAMP1, IFNγ and IgY genes in two case and control assays. …”
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Migrant Health Country Profile tool (MHCP-t) for transforming health data collection and surveillance in the Middle East and North African (MENA) region: tool development protocol... by Farah Seedat, Bouchra Assarag, Kolitha Wickramage, Sally Hargreaves, Ana Requena-Mendez, Dominik Zenner, Anna Deal, Stella Evangelidou, Oumnia Bouaddi, Moudrick Abdellatifi, Hassan Edries, Eman Elafef, Taha Maatoug, Anissa Ouahchi, Sara Arias, Adel Abdelkhalek, Ibrahim Ahmed Bani, Kenza Hassouni, Mahmoud Hilali, Mohamed Khalis, Wejdene Mansour, Ali Mtiraoui, Hassan Chrifi, Mohamed Douagi, Abdedayem Khelifi

“…The revised indicators will be entered into an electronic data capture system and the tool will be pilot-tested by applying a mixed-methods process evaluation to examine its relevance, comprehensiveness, comprehensibility and other practical issues, such as completion time and ease of responding. Mechanisms of change will be assessed on how the participative interactions towards the tool development can trigger change at national and regional levels.Ethics and dissemination The study protocol has been approved by the institutional review boards at the Hospital Clinic in Barcelona, Spain, the University of Sousse in Sousse, Tunisia, the University Hospital of Tanger, Morocco and Badr University of Cairo in Egypt. …”
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Supervised Injecting Room Cohort Study (SIRX): study protocol by Lisa Maher, Thomas Kerr, Matthew Hickman, Alexander Thompson, Peter Higgs, Paul Dietze, Paul A Agius, Nick Scott, Daniel O’Keefe, Mark A Stoové, Jack Stone, Dylan Vella-Horne, Ashleigh C Stewart, Amanda Roxburgh, Sione Crawford, Josephine Norman, Zachary Lloyd, Nico Clark

“…Participants are informed of their right to withdraw from the study at any time and that withdrawing does not impact their access to services. …”
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Structure of Patients with Hepatocellular Cancer (Data Analysis from Two Specialised Centres) by M. V. Mayevskaya, M. S. Novruzbekov, I. M. Borovkov, D. G. Trofimova, M. S. Zharkova, V. D. Lunkov, K. N. Lutsyk, O. D. Olisov

“…In the analysis of HCC patients, the ratio of men to women was 3:1 (64 men and 22 women), the median age was 54.5 years (IQR 48–59). The median time from the establishment of chronic liver disease to the detection of HCC was 7.5 years (IQR 3–14.5). …”
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Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…Methods Twenty-four patients with histologically confirmed neuroendocrine tumor, who underwent clinically indicated [18F]SiTATE PET/CT examination (3.0 MBq/kg, 5 min PET scan time) on a Siemens Biograph Vision Quadra LAFOV PET/CT, were included retrospectively in this study. …”
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Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

“…Meta-analyses for preterm birth, spontaneous abortion and small-for-gestational-age birth demonstrated no significant associations with seasonal influenza vaccination. Immortal time bias was observed in a sensitivity analysis of meta-analysing risk-based preterm birth data. …”
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Impact of protein intake from a caloric-restricted diet on liver lipid metabolism in overweight and obese rats of different sexes by Ying Tian, Jiawei Gong, Zhiyan He, Suwen Peng, Yuping Huan, Hongpeng Cao

“…A 40% energy restriction can significantly reduce the body weight, body fat, liver fat, and the blood concentration of TG in both male and female overweight and obese rats, but it can significantly increase the blood concentration of TC in overweight and obese male rats. At the same time of 40% calorie restriction, increasing dietary protein intake to twice the normal protein intake has a stronger effect on promoting hepatic triglyceride oxidation and reducing liver fat content in the male overweight and obese rats by increasing the levels of adiponectin and leptin in the blood, and can also significantly reduce the plasma cholesterol concentration in the female overweight and obese rats through inhibiting cholesterol synthesis most likely by increasing glucagon level in the blood.…”
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Effect of colloidal particle size on physicochemical properties and aggregation behaviors of two alkaline soils by Y. Yan, X. Zhang, C. Xu, C. Xu, J. Liu, F. Hu, F. Hu, Z. Geng, Z. Geng

“…The organic and inorganic carbon contents, clay mineralogy and surface electrochemical properties, including surface functional groups and zeta potentials, were characterized. Through a time-resolved light scattering technique, the aggregation kinetics of soil colloidal fractions were investigated, and their critical coagulation concentrations (CCCs) were determined. …”
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Donor-Specific Anti-Human Leukocyte Antigen Antibodies Predict Prolonged Isolated Thrombocytopenia and Inferior Outcomes of Haploidentical Hematopoietic Stem Cell Transplantation by Xiaosu Zhao, Xiangyu Zhao, Mingrui Huo, Qiaozhen Fan, Xuying Pei, Yu Wang, Xiaohui Zhang, Lanping Xu, Xiaojun Huang, Kaiyan Liu, Yingjun Chang

“…Our results, for the first time, suggest an association of DSAs with PT after unmanipulated HBMT. …”
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Five-Year Follow-Up of a Slowly Resorbable Biosynthetic P4HB Mesh (Phasix) in VHWG Grade 3 Incisional Hernia Repair by L. M. Van den Dop, MD, M. M. J. Van Rooijen, MD, PhD, T. Tollens, MD, L. N. Jørgensen, MD, PhD, T. S. De Vries-Reilingh, MD, PhD, G. Piessen, MD, PhD, F. Köckerling, MD, PhD, M. Miserez, MD, PhD, M. Dean, MD, F. Berrevoet, MD, PhD, B. Dousset, MD, PhD, H. L. Van Westreenen, MD, PhD, F. Gossetti, MD, PhD, G. W. M. Tetteroo, MD, PhD, A. Koch, MD, PhD, M. F. Boomsma, MD, PhD, J. F. Lange, MD, PhD, J. Jeekel, MD, PhD

“…In total, 61/84 (72.6%) patients were seen. Median follow-up time was 60.0 [interquartile range (IQR): 55–64] months. …”
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First-year dynamics of the anaerobic microbiome and archaeome in infants’ oral and gastrointestinal systems by Charlotte J. Neumann, Rokhsareh Mohammadzadeh, Pei Yee Woh, Tanja Kobal, Manuela-Raluca Pausan, Tejus Shinde, Victoria Haid, Polona Mertelj, Eva-Christine Weiss, Vassiliki Kolovetsiou-Kreiner, Alexander Mahnert, Christina Kumpitsch, Evelyn Jantscher-Krenn, Christine Moissl-Eichinger

“…In contrast to this, we could track specific bacterial strains transitioning from oral to gut or persisting in the gut over time.…”
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