Orbital cycle records in shallow unconsolidated sediments: implications for global carbon cycle and hydrate system evolution in deep-sea area sediments of the Qiongdongnan Basin by Yang Dong, Yang Dong, Ren Wang, Ren Wang, Jinqiang Liang, Yulin He, Jinfeng Ren, Wanzhong Shi, Wanzhong Shi, Xiaosong Wei, Xiaosong Wei, Hao Du, Hao Du, Xiangyang Xie, Arthur B. Busbey

“…IntroductionMilankovitch theory has extensive application in sequence stratigraphy and the establishment of time scales. However, it is rarely applied to shallow strata rich in hydrates. …”
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Phase I study of pembrolizumab in combination with ibrutinib for the treatment of unresectable or metastatic melanoma by Yuan Yao, Yiyi Yan, Vera J. Suman, Allan B. Dietz, Courtney L. Erskine, Anastasios Dimou, Svetomir N. Markovic, Svetomir N. Markovic, Robert R. McWilliams, Heather N. Montane, Matthew S. Block, Matthew S. Block

“…Pembrolizumab (200 mg/kg every 3 weeks) was combined with ibrutinib, administered orally at the dose assigned at the time of registration (140 mg daily, 280 mg daily, and 420 mg daily). …”
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Effect of Electroacupuncture on Hippocampal Functional Activity and Molecular Expression Profile in Rats with Vascular Cognitive Impairment by WANG Zeyu, DING Yanyi, DAI Yaling, YANG Minguang, HUANG Jia, ZHANG Shenghang

“…The electroacupuncture group was intervented by stimulating at Baihui (GV20) and Shenting (GV24) acupoints, the frequency of electroacupuncture was 1/20 Hz, 30 min each time, once a day, dilatational wave, continous intervention for 28 days, and the other two groups were grabbed under the same conditions without any other intervention. …”
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Characterization and dosimetric predictors for absolute lymphocyte count changes during neoadjuvant chemoradiotherapy with or without pembrolizumab for esophageal squamous cell car... by Wei-Xiang Qi, Shuyan Li, Shujun Zhang, Chao Li, Huan Li, Xiaomei Li, Chaofen Zhao, Gang Cai, Cheng Xu, Xuan Han, Yibin Zhang, Jiayi Chen, Shengguang Zhao

“…Compared to nCRT alone, the addition of pembrolizumab to nCRT significantly improve lymphopenia recovery in the 1-months after nCRT (p = 0.0003), but the ALC at other time point during nCRT and ALC nadir was comparable between the two groups. …”
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KATALIKŲ BAŽNYČIOS KAITA LIETUVOJE TRANSFORMACIJŲ LAIKOTARPIU by Valdas Pruskus

“…CHANGES OF CATHOLIC CHURCH IN LITHUANIA IN TIME OF TRANSFORMATIONS Valdas Pruskus Summay After the restoration of independence of Lithuania, changing of Catholic Church as an institution was predetermined by two most important factors. …”
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1-(5-ACETYL-3-METHYL-6-PHENYL-5H-[1,2,4]TRIAZOLO [3,4-b][1,3,4]THIADIAZIN-7-YL)-ETHANONE: DOSE-DEPENDENCE OF ANALGESIC EFFECT, LACK OF OPIOIDERGIC MECHANISM OF ACTION, EFFECT ON BE... by Andriy Koval, Sergiy Shtrygol

“…The average increase in the LP nociceptive response during its use per se was 306.3%, and during the previous blockade of opioid receptors with naloxone - 204.4%, that is, it decreased on average by a third, and the median of the final latent time decreased by 2 times with almost the same initial value. …”
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Effects of Physical Exercise Breaks on Executive Function in a Simulated Classroom Setting: Uncovering a Window into the Brain by Qian Yu, Zhihao Zhang, Sebastian Ludyga, Kirk I. Erickson, Boris Cheval, Meijun Hou, Dominika M. Pindus, Charles H. Hillman, Arthur F. Kramer, Ryan S. Falck, Teresa Liu‐Ambrose, Jin Kuang, Sean P. Mullen, Keita Kamijo, Toru Ishihara, David A. Raichlen, Matthew Heath, David Moreau, André O. Werneck, Fabian Herold, Liye Zou

“…Linear mixed models identified significant positive effects of exercise conditions on behavioral reaction time (RT), error rate, and inverse efficiency score (β = −2.62, −0.19, −3.04: ps < 0.05). …”
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Model-Based Variation-Aware Optimization for Offset Calibration and Pre-Sensing in DRAM Sense Amplifiers by Dongyeong Kim, Geon Kim, Suyeon Kim, Jewon Park, Sinwook Kim, Hyeona Seo, Chaehyuk Lim, Sowon Kim, Juwon Lee, Jeonghyeon Yun, Hyerin Lee, Jinseok Park, Yongbok Lee, Seungchan Lee, Myoungjin Lee

“…While HSPICE simulations combining Monte Carlo (MC) and binary search methods require numerous iterations for single design point verification, our model significantly reduces design time by effectively narrowing the region of interest through pre-optimization using statistical characteristics. …”
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Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

“…Critically, this work for the first time reveals regulation of L-methionine (L-met) production within the activated methyl cycle (AMC) by small RNA (sRNA) CjNC110 as a key factor driving C. jejuni optimal chicken colonization. …”
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KiKli Fit: Insights into the Development and Practice of a Physical Activity Program in Pediatric Cancer by Lisa Hillebrech, Lars Rehbein, Ann Christin Schneider, Sara Müller, Christina Schindera, Katharina Eva, Valentin Benzing

“…Building on this, a PA program was designed and implemented over 1.5-years. During this time, various formal and informal assessments were conducted to ensure quality assurance. …”
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Changing consumption of resources for respiratory support and short-term outcomes in four consecutive geographical cohorts of infants born extremely preterm over 25 years since the... by Alicia J Spittle, Lex W Doyle, Peter J Anderson, Li Huang, Jeanie L Y Cheong, Alice C Burnett, Anjali Haikerwal, Merilyn Bear, Margaret Charlton, Janet Courtot, Noni Davis, Julianne Duff, Rachel Ellis, Marie Hayes, Elisha Josev, Elaine Kelly, Marion Mcdonald, Emma Mcinnes, Bronwyn Novella, Gillian Opie, Gehan Roberts, Katherine Scott, Penelope Stevens, Anne-marie Turner, Kim M Dalziel, Katherine Lee, Marissa Clark, Joy E Olsen, Rosemarie A Boland, Alice E Stewart, Leah M Hickey

“…The average additional costs associated with one additional infant surviving in 2016–2017 were 200 (95% CI 150 to 297) days, 326 (183 to 1127) days and 130 (70 to 267) days compared with 1991–1992, 1997 and 2005, respectively.Conclusions Consumption of resources for respiratory support has escalated with improved survival over time. Cystic periventricular leukomalacia reduced in incidence but retinopathy of prematurity requiring treatment increased. …”
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Spatial and temporal heterogeneity of soil respiration in a bare-soil Mediterranean olive grove by S. Aranda-Barranco, S. Aranda-Barranco, P. Serrano-Ortiz, P. Serrano-Ortiz, A. S. Kowalski, A. S. Kowalski, E. P. Sánchez-Cañete, E. P. Sánchez-Cañete

“…The results indicate that <span class="inline-formula"><i>R</i>_{s  Under-Tree}</span> was 3 times higher than <span class="inline-formula"><i>R</i>_s Alley</span> in the annual computations. …”
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The role of artificial intelligence and machine learning in predicting and combating antimicrobial resistance by Hazrat Bilal, Muhammad Nadeem Khan, Sabir Khan, Muhammad Shafiq, Wenjie Fang, Rahat Ullah Khan, Mujeeb Ur Rahman, Xiaohui Li, Qiao-Li Lv, Bin Xu

“…In addition, AI-based clinical decision support systems in real-time guide healthcare professionals to improve prescribing of antibiotics. …”
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Monitoring the Concentrations of Na, Mg, Ca, Cu, Fe, and K in <i>Sargassum fusiforme</i> at Different Growth Stages by NIR Spectroscopy Coupled with Chemometrics by Sisi Wei, Jing Huang, Ying Niu, Haibin Tong, Laijin Su, Xu Zhang, Mingjiang Wu, Yue Yang

“…Currently, the determination of minerals in <i>S. fusiforme</i> primarily relies on inductively coupled plasma mass spectrometry and other methods, which are time-consuming and labor-intensive. Thus, a rapid and convenient method was developed for the determination of six minerals (i.e., Na, Mg, Ca, Cu, Fe, and K) in <i>S. fusiforme</i> via near-infrared (NIR) spectroscopy based on chemometrics. …”
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Multi-observatory Study of Young Stellar Energetic Flares (MORYSEF): No Evidence for Abnormally Strong Stellar Magnetic Fields after Powerful X-Ray Flares by Konstantin V. Getman, Oleg Kochukhov, Joe P. Ninan, Eric D. Feigelson, Vladimir S. Airapetian, Abygail R. Waggoner, L. Ilsedore Cleeves, Jan Forbrich, Sergio A. Dzib, Charles J. Law, Christian Rab, Daniel M. Krolikowski

“…We explore the empirical power-law relationship between X-ray luminosity ( L _X ) and total surface magnetic flux (Φ), established across solar magnetic elements, time- and disk-averaged emission from the Sun, older active stars, and pre-main-sequence (PMS) stars. …”
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Quality evaluation and influencing factors analysis of 6-minute walking test in coronary heart disease patients (冠心病患者6分钟步行试验质量评价与原因分析) by WANG Shanshan (王珊珊)

“…It is suggested that quality of 6MWT should be strengthened from following aspects: patient health education, kinesiophobia, financial burden, time of conducting 6MWT after PCI and role of cardiac rehabilitation specialist nurses. …”
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Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma by Yining Zhang, Zhenfang Li, Chengchi Zhang, Chengying Shao, Yanting Duan, Guowan Zheng, Yu Cai, Minghua Ge, Jiajie Xu

“…Optical technology offers distinctive possibilities for early preoperative diagnosis, intraoperative real-time visualization of tumor margins, sentinel lymph node biopsies, phototherapy. …”
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Experimental use of mycobacterial antigens in tuberculin skin test on water buffalo by Alessandra Martucciello, Federica Signorelli, Piera Mazzone, Francesco Grandoni, Giovanna Cappelli, Lucia Boccia, Giuseppe Parente, Monica Cagiola, Maria Beatrice Boniotti, Esterina De Carlo, Francesco Napolitano, Giorgio Galiero

“…Negative subjects also exhibited a skin response to PPDB at 24 and 48 h, but it became completely negative at 72 h, the prescribed reading time. In the positive buffaloes, the kinetics of skin responses showed that the strongest response was to PPDB at 24h, with some subjects becoming doubtful at 72 and 96 h. …”
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Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial by Michael Walsh, Salim Yusuf, Chirag Parikh, Jessica Vincent, P J Devereaux, Francois Lamontagne, Matthew T V Chan, Richard Whitlock, Meaghan Cuerden, Amit X Garg, Andre Lamy, Daniel I Sessler, Kevin Teoh, Ainslie Hildebrand, Yunxia Zuo, Pallav Shah, Seyed Hesameddin Abbasi, Mackenzie Quantz, Jean-Pierre Yared, Nicolas Noiseux, Georgios Tagarakis, Antoine Rochon, Janice Pogue, Abbas Salehiomran

“…Introduction Steroids In caRdiac Surgery trial (SIRS) is a large international randomised controlled trial of methylprednisolone or placebo in patients undergoing cardiac surgery with the use of a cardiopulmonary bypass pump. At the time of surgery, compared with placebo, methylprednisolone divided into two intravenous doses of 250 mg each may reduce the risk of postoperative acute kidney injury (AKI).Methods and analysis With respect to the study schedule, over 7000 substudy eligible patients from 81 centres in 18 countries were randomised in December 2013. …”
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Human head and neck cancer cell lines response to cold atmospheric plasma activated media is affected by the chemistry of culture media by Viviana di Giacomo, Marwa Balaha, Asia Pece, Ilaria Cela, Gianluca Fulgenzi, Giovanna Orsini, Tatiana Spadoni, Tirtha Raj Acharya, Nagendra Kumar Kaushik, Eun Ha Choi, Monica Rapino, Mariangela Mazzone, Gabriella Mincione, Gianluca Sala, Eloisa Sardella, Vittoria Perrotti

“…The impact of PAM obtained from exposure to CAP for different times was evaluated in three head and neck cancer (HNC) cell lines (HSC3, FaDu, CAL-27). …”
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