Transfer from long-term care to acute care and risk of new permanent cognitive or physical disability among long-term care residents in Canada: protocol for a retrospective cohort... by Sharon Kaasalainen, Daniel I McIsaac, Steven Hawken, Daniel Kobewka, Peter Tanuseputro, Amy Hsu, Robert Talarico, Colleen Webber, Ramtin Hakimjavadi, Celeste Fung, Mary M Scott, Doug Manuel, Christina Y Yin, Jackie Kierulf, Frank Molnar, Sandy Shamon, Aliza Moledina

“…The outcomes are (1) subsequent new permanent physical disability, (2) subsequent new permanent cognitive disability and (3) all-cause mortality. Due to the time-varying nature of the exposure and confounders, we will use an extended cause-specific Cox regression model to explore this relationship. …”
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Food for thought: a qualitative assessment of medical trainee and faculty perceptions of nutrition education by Olivia Kunitsky, Mahdi Taye, Karla Feeley, Hugh Johnson, Abigail Glynn, Avery Stivale, Matthew Hamers, Alexis Notarianni, Sireesha Mamillapalli, Gabi Waite, Sonia Lobo

“…For barriers, the qualitative analysis identified these themes: (1) time constraints, (2) assessment and prioritization, (3) insufficient faculty expertise, and (4) bias and stigma. …”
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Weekend-Based Parent-Group Intervention to Reduce Stress in Parents of Children and Adolescents with Type 1 Diabetes: A Pilot Study by Lucia Ferrito, Barbara Predieri, Dorina Pjetraj, Maria Cristina Alessandrelli, Manuela Pagnini, Antonio Iannilli, Monica Marino, Stefano Tombolini, Basilio Pintaudi, Giuseppe Lucisano, Fabiana Zani, Lorenzo Iughetti, Antonio Nicolucci, Valentino Cherubini

“…Intervention was based on the reexamination of the traumatic event of diagnosis of T1D through spatial and time-line anchorage, retracing of the future, emotional awareness, and interactive discussion. …”
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Distinct sex differences in ethanol consumption and operant self-administration in C57BL/6J mice with uniform regulation by glutamate AMPAR activity by Sara Faccidomo, Sara Faccidomo, Vallari R. Eastman, Taruni S. Santanam, Katarina S. Swaim, Seth M. Taylor, Clyde W. Hodge, Clyde W. Hodge

“…Sex-specific differences in neural regulation of EtOH reinforcement were examined by testing the effects of a glutamate AMPA receptor antagonist on operant EtOH self-administration.ResultsFemale C57BL/6J mice exhibited a time-dependent escalation in EtOH intake under both continuous and limited access conditions. …”
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Work–health–personal life conflicts in naive patients with chronic hepatitis B receiving initial treatment in China: a qualitative study by Li Zhang, Ying Chen, Ying Li, Hongmei Wang, Lin Zhu, Xiaoyang Lu, Yingjing Zheng, Donald Patrick, Fengjiao Xu, Mengna Song, Xiao Cheng, Boyan Chen

“…Objectives People with chronic hepatitis B (CHB) perform sick roles, work roles and personal roles simultaneously. At times, role conflicts arise because of failure to meet the expectations of different roles. …”
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Discussion on standardization of Traditional Chinese Medicine nursing appropriate Technology based on Traditional Chinese Medicine nursing inheritance (基于中医护理传承构建标准化中医护理适宜技术)... by LIU Hongxin (刘红鑫), GUO Hailing (郭海玲), TIAN Runxi (田润溪), WANG Fang (王芳), GAO Ning (高宁), ZHENG Liping (郑莉萍), LI Yufeng (李玉凤), YU Liying (于丽英)

“…It can help to provide basis for clinical optimization of TCM nursing appropriate technology and provide efficient nursing mode for patients. At the same time, to cultivate high-level TCM nursing talents with evidence-based thinking and nursing practice ability. …”
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Integrative analysis of miRNA expression data reveals a minimal signature for tumour cells classification by Sabrina Napoletano, David Dannhauser, Paolo Antonio Netti, Filippo Causa

“…Our results demonstrate a highly significant differentiation of cancer types, achieving 100 % classification accuracy with minimal training time using a streamlined miRNA signature. Validation of the miRNA profile confirms that each of the three identified miRNAs regulates distinct biological pathways with minimal overlap. …”
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Two Approaches to Cognitive Evaluation: Assessing the Strengths and Limitations of GPCOG and ACE-III by Magdalena Mąka, Dominik Sikora, Piotr Oleksy, Adam Zając, Karol Zieliński, Łukasz Papież, Ewa Góralczyk, Jakub Kamiński, Bartosz Buczkowski, Dagmara Wochnik

“…It excels in assessing complex dementia but is time-intensive and requires trained personnel, limiting its use in primary care. …”
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Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4 by Arushi Vats, Luca Braga, Nezka Kavcic, Paola Massimi, Edoardo Schneider, Mauro Giacca, Laimonis A. Laimins, Lawrence Banks

“…This study, for the first time, identifies a novel ubiquitin ligase, FBXO4 that targets the degradation of HPV E6 oncoprotein in the absence of E6AP in cervical cancer-derived cell lines. …”
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Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study by Daiki Yamashige, Susumu Hijioka, Yoshikuni Nagashio, Yuta Maruki, Soma Fukuda, Shin Yagi, Kohei Okamoto, Hidenobu Hara, Yuya Hagiwara, Daiki Agarie, Tetsuro Takasaki, Akihiro Ohba, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Miyuki Sone, Yutaka Saito, Takuji Okusaka

“…Results Of 133/68 patients who underwent 6-mm/10-mm-diameter FCSEMS deployment, 59 in each group were selected. The median time to recurrent biliary obstruction was not significantly different between the groups (p=0.46). …”
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Effect of skill-based educational training for ambulance personnel on neonatal transport for newborn care in coastal South India – a single arm intervention study [version 2; peer... by Shantharam Baliga B, Harsha Lashkari P, Sowmini Padmanabh Kamath, Leslie Lewis, Subhodh Shetty S, Santosh Kalyan, Ramesh Holla, Suchitra Shenoy M

“…Of 53 neonates studied post intervention, there was a significant reduction in hypothermia (17% vs. 48.4%, p < 0.001), hypoglycemia (16.9% vs. 38.7%, p=0.010), and prolonged capillary refill time (71.7% vs. 46.8%, p=0.042), improvement in the use of intravenous fluids (69.8% vs. 29%, p <0.001), a reduction in growth from umbilical swabs (15.1% vs. 42%, p=0.002) and duration of NICU stay (p = 0.001). …”
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Clinical Features of COVID‐19 Associated Pulmonary Aspergillosis: A Multicenter, Retrospective Study by Yasheng Zhan, Guojun He, Cheng Zhong, Yake Yao, Jiangying Zhou, Tong Li, Hua Zhou

“…All seven cases acquired CAPA in the ICU, six cases during MV, of which five cases received ECMO treatment at the same time, and one case had been off ventilation. The average duration from onset of COVID‐19 to CAPA was 25.4 days, from ICU admission to CAPA was 23.4 days, and from MV to CAPA was 22.1 days. …”
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Influence law and control mechanism of coal seam permeability on coal and gas outburst by Chaolin ZHANG, Mingliang LIU, Enyuan WANG, Peizhong WANG, Qiaozhen JIANG, Wei ZENG

“…With the increase of coal seam permeability, the resistance to gas flow decreases, and the gas pressure decreases rapidly, making it difficult to form a high gas pressure gradient. At the same time, the seepage force near the exposed surface is low and quickly transfers to the distant location, unable to further damage the exposed coal seam, resulting in the decrease of outburst strength or even no outburst. …”
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A review of the research progress on nursing measures in cardiac rehabilitation with integrated Chinese and western medicine (中西医结合心脏康复护理研究进展) by ZHANG Wenjuan (张文娟), TIAN Hongyan (田洪燕), GEN Ao (耿敖), XU Xiao (徐笑), ZHANG Xuan (张璇), YU Meili (于美丽), YUE Zong (岳宗), CHEN Liang (陈亮)

“…However, due to the limitations of our country’s social support system, traditional concepts, and medical insurance system, the development of cardiac rehabilitation in China is still in its infancy and is facing huge challenges; at the same time, how to integrate Traditional Chinese Medicine into the existing cardiac rehabilitation system, to create a cardiac rehabilitation theory and specific practice with Chinese characteristics is also a hot topic of current research. …”
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Gut Dysbiosis and Abnormal Bile Acid Metabolism in Colitis-Associated Cancer by Li Liu, Min Yang, Wenxiao Dong, Tianyu Liu, Xueli Song, Yu Gu, Sinan Wang, Yi Liu, Zaripa Abla, Xiaoming Qiao, Wentian Liu, Kui Jiang, Bangmao Wang, Jie Zhang, Hailong Cao

“…Intestinal inflammation, mucosal barrier, and bile acid receptors were determined by real-time PCR and immunohistochemistry. Fecal microbiome and bile acids were detected via 16S rRNA sequencing and liquid chromatography-mass spectrometry. …”
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Genetic and biochemical characterization of staphylococci occurring in Novosibirsk, Russia by Y. N. Kozlova, N. V. Fomenko, V. V. Morozova, I. V. Saranina, A. Yu. Tikunov, D. A. Ganichev, A. G. Samokhin, V. V. Pavlov, O. M. Rozhnova, I. A. Bondar’, E. V. Zenkova, V. V. Nimaev, V. V.  Klimontov, N. V. Tikunova

“…Identification of coagulase positive strains was performed using a standard biochemical method and by real­time PCR of the coa gene. 100 % coincidence between the presence of the gene and coagulase activity for S. aureus strains was recorded, which suggests that detection of the coa gene can be used as a correct method for S. aure us identification. …”
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Overexpression of MMP13 Is Associated with Clinical Outcomes and Poor Prognosis in Oral Squamous Cell Carcinoma by Vui King Vincent-Chong, Iman Salahshourifar, Lee Peng Karen-Ng, Ming Yhong Siow, Thomas George Kallarakkal, Anand Ramanathan, Yi-Hsin Yang, Goot Heah Khor, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Narayanan Prepageran, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Sok Ching Cheong, Rosnah Binti Zain

“…Copy number, mRNA, and protein expression analysis of MMP13 were determined using real-time quantitative PCR and immunohistochemistry methods in OSCC samples. …”
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Solid and Gaseous Methane in IRAS 23385+6053 as Seen with Open JWST Data by Ruslan Nakibov, Varvara Karteyeva, Igor Petrashkevich, Maksim Ozhiganov, Mikhail Medvedev, Anton Vasyunin

“…The derived column densities are ${N}_{{\,\rm{CH}\,}_{4}}$ (CO _2 ) = $2.9{7}_{-0.57}^{+0.37}\times 1{0}^{17}$ cm ^−2 and ${N}_{{\,\rm{CH}\,}_{4}}$ (H _2 O) = $1.0{2}_{-0.27}^{+0.46}\times 1{0}^{17}$ cm ^−2 . …”
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COVID-19 pandemic and vaccination rate in patients with psoriasis treated with biologics: A single center experience by Milčić Danijela, Malinić Marija, Ćirković Anđa, Krupniković Doroteja, Milinković-Srećković Mirjana

“…The therapy with biologics was successful regardless of the short-term interruption of drug administration due to the beginning of the COVID-19 pandemic and the worsening of psoriasis in some patients during that time.…”
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Pragmatic performance, its relationship with symptom severity, and early clinical predictors of pragmatics in 5 ~ 6-year-old children with autism spectrum disorder by Lu Qian, Ning Ding, Hui Fang, Ting Xiao, Bei Sun, HuiYun Gao, XiaoYan Ke

“…Additionally, given the close correlation between the LUI-Mandarin score and symptom severity on the ADOS/ADI-R, the LUI-Mandarin might be a good way to triage children who need to wait a long time for a more extensive evaluation. Furthermore, this study provides new insights into potential targets for pragmatic interventions, and interventions can be designed to promote SJE between caregivers and children in future work.…”
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