Outcomes of Idecabtagene Vicleucel Therapy in Patients with Relapsed/Refractory Multiple Myeloma: A Single-Institution Experience by Aaron Trando, Farid Ghamsari, Philip Yeung, Caitlin Costello, Ila Saunders, Ah-Reum Jeong

“…Six of these eleven patients remained alive at time of data cutoff. Univariate and multivariate analysis revealed no significant predictors of ORR, PFS, or OS. …”
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Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…Reductions in mean FMD [test group −3.43%; 95% confidence interval—CI [−2.68; 9.54], p = 0.487; control group −6.75%; 95% CI [1.29; 12.22], p = 0.012] and cIMT (test group −0.05 mm; 95% CI [0.01; 0.10], p = 0.014; control group −0.01 mm; 95% CI [−0.03; 0.05], p = 1.000) were observed in both groups from baseline to 6 months, without significant intergroup differences at any time-point. Differences between groups in serum inflammatory markers were detected at baseline and 3 days for interleukin (IL)-18, and at 10 days for IL-8.ConclusionPreliminary results from the present pilot study showed that steps 1 and 2 of periodontal treatment in subjects with periodontitis in stages III–IV and established cardiovascular disease induced improvements in cIMT and periodontal outcomes, although changes in FMD were not observed. …”
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The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows by Zheng Zhou, Kang Yong, Zhengzhong Luo, Zhenlong Du, Tao Zhou, Xiaoping Li, Xueping Yao, Liuhong Shen, Shumin Yu, Yixin Huang, Suizhong Cao

“…The levels of serum biochemical indices were measured at three time points in the three groups using commercial kits. …”
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Knowledge, attitudes and behaviour towards ticks and tick-borne diseases—A survey among Lyme borreliosis cases in Bavaria in 2019 by Stefanie Böhm, Volker Fingerle, Andreas Beyerlein, Manfred Wildner, Merle M. Böhmer

“…Even though a majority perceived checking for ticks after spending time outdoors, wearing long clothes, wearing closed shoes and tucking pants in socks as effective protection measures against tick bites, a much lower proportion applied those measures frequently (proportions perceived vs. applied: 99.2 % vs. 72.1%; 93.8 % vs. 40.2 %, 88.8 % vs. 51.1 % and 85.4 % vs. 16.8 %, respectively).Identified lack of knowledge or misconception regarding risk factors, availability of protection measures and tick behaviour may hamper application of recommended protection measures. …”
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Comparison of the safety of esophagojejunal overlap and π-shaped anastomosis in totally laparoscopic total gastrectomy by Tongkun Song, Maoxing Liu, Kai Xu, Jiadi Xing, Kechen Guo, Xinyu Qi, Pin Gao, Fei Tan, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Ming Cui, Xiangqian Su

“…No significant difference was found in the operation time, intraoperative blood loss, and postoperative hospital stay between the two anastomosis methods (p > 0.05); however, the π-shaped anastomosis group had more postoperative anastomotic leakage (p < 0.05). …”
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Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization by Liangliang FAN, Limei REN, Song YANG, Wenjing LI, Yueming ZHAO, Ronghua ZHAO, Daqing ZHAO, Jiawen WANG

“…Methods: The CCK-8 assay was employed to detect the effect of GDNPs on the viability of macrophages (RAW264.7). Real-time quantitative PCR was utilized to detect the transcript levels of IL-6, iNOS, TNF-α, and MCP-1, which were indicators related to the M1 polarization of macrophages stimulated by GDNPs. …”
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Prevalence of AZFс Y chromosome microdeletions and association with spermatogenesis in Russian men from the general population by L. V. Osadchuk, G. V. Vasiliev, M. K. Ivanov, M. A. Prasolova, M. A. Kleshchev, A. V. Osadchuk

“…To identify AZF microdeletions, the presence/ absence of 15 STS markers was analyzed using multiplex real-time polymerase chain reaction. Age, weight, height, and the volume, concentration, total count, proportion of motile and morphologically normal spermatozoa in the ejaculate were recorded for all participants. …”
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Relationship of the gene pool of the Khants with the peoples of Western Siberia, Cis-Urals and the Altai-Sayan Region according to the data on the polymorphism of autosomic locus a... by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, M. G. Svarovskaya, A. V. Marusin, I. Yu. Khitrinskaya, V. A. Stepanov

“…The specificity of haplotypes, the discovery of various terminal SNPs confirms that the Khanty did not come into contact with other ethnic groups for a long time, except for the Nenets, which included many Khanty clans.…”
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Revealing the role of natural killer cells in ankylosing spondylitis: identifying diagnostic biomarkers and therapeutic targets by Yuling Chen, Yan Li, Yuan Xu, Qing Lv, Yuanchun Ye, Jieruo Gu

“…The diagnostic value of the identified key genes was evaluated using ROC curves, logistic regression analysis, and a nomogram. Real-time PCR (RT-PCR) was used to quantified the expression of genes. …”
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Characterization of the bioaccumulation and toxicity of copper pyrithione, an antifouling compound, on juveniles of rainbow trout by Bourdon, Charlotte, Cachot, Jérôme, Gonzalez, Patrice, Couture, Patrice

“…The expression of genes involved in the antioxidant response (sod1, sod2, gpx), detoxification (cyp1a, mt1x, mt2x), Cu transport (ctr1, ctr2, slc11a2), energy metabolism (AcoAc, cox, 12S) and cell cycle regulation (bax) strongly decreased at Day 8 in the gills and at Day 16 in the liver of CuPT-exposed fish in comparison to controls at the same time point. This study clearly showed that the toxicity of Cu in the form of CuPT was much higher than that of ionic Cu from CuSO4and provides new information on the compound that will be useful to develop regulations concerning its use and release in the aquatic environment. …”
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Enhancing sustainable solid waste management through separate source collection by O. Arabiyat, J.T. Al-Bakri, F. Kölsch, S. Al-Omari, H. Aladwan

“…An overall assessment was carried out for the economic benefit of separate source collection.FINDINGS: Analyses of waste generation in the study area showed that the average quantity of municipal waste was 0.89 kilogram per capita per day, and there is a trend that shows an increase in municipal solid waste quantities with respect to time. A significant amount of municipal solid waste (60 percent) has an organic composition, while recyclable waste constitutes about 12.5 percent of the total municipal solid waste. …”
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Research Progress of Intelligent Evaluation and Virtual Reality Based Training in Upper Limb Rehabilitation afrer Stroke by XIE Qiurong, LIN Wanqi, ZHANG Qi, SHENG Bo, ZHANG Yanxin, HUANG Jia

“…Automated assessment of upper extremity motor function based on machine learning algorithms with markerless sensing techniques has focused on the Fugl-Meyer assessment of upper extremity (FMA-UE), Brunnstrom stages, and Wolf motor function test (WMFT) scales and has been proved with high-scoring accuracy and time efficiency. In addition, virtual reality (VR) training designed for neurorehabilitation can effectively promote recovery of upper limb function after stroke. …”
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Case report: Successful treatment of hyperbaric oxygen for radiation-induced hemorrhagic cystitis in a 95-year-old patient with bladder cancer by Li Lin, Li Lin, Man He, Yanyan Zeng, Xiaoxiao Ni, Yequn Guo, Xiaojuan Xie, Lingling Sun, Huai Huang

“…Moreover, it also records a comprehensive dataset, including the time of the patient’s recurrence of hematuria and the subsequent trend of hematuria control, which contributes valuable evidence to the research on HBOT for the repair of bladder mucosal tissue.…”
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Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns by Yusufjon Gafforov, Manzura Yarasheva, Xue-Wei Wang, Milena Rašeta, Yelena Rakhimova, Lyazzat Kyzmetova, Kanaim Bavlankulova, Sylvie Rapior, Jia-Jia Chen, Ewald Langer, Burkhon Munnavarov, Zafar Aslonov, Bobozoda Bakokhoja, Li-Wei Zhou

“…These macrofungi play essential ecological roles as saprotrophs and pathogens of various identified host plant families, aiding in lignin degradation and exhibiting diverse enzymatic activities. For the first time, we modelled the potential distribution patterns of Hymenochaetoid fungi in Central Asia, revealing that their distribution is strongly influenced by host plant availability and temperature-related factors. …”
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AI-based carbon peak prediction and energy transition optimization for thermal power industry in energy-intensive regions of China by Chenhao Huang, Zhongyang Lin, Jian Wu, Penghan Li, Chaofeng Zhang, Yanzhao Liu, Weirong Chen, Xin Xu, Jinsong Deng

“…Lastly, the tailored energy transition strategies were suggested according to the spatial distributions of carbon peak time nodes under each scenario. The results showed that, compared to the baseline, the carbon peak under the Economic Development Scenario will be delayed by three years, with an additional 92.74 Mt CO2; while under the Environmental Protection and Energy Transition Scenarios, the peak will be advanced by five and three years, with 106.48 and 73.86 Mt CO2 reductions, respectively. …”
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Robot-Assisted versus Laparoscopic-Assisted Gastrectomy among Gastric Cancer Patients: A Retrospective Short-Term Analysis from a Single Institution in China by Li-Fei Sun, Kai Liu, Xue-Shang Su, Xuan Wei, Xiao-Long Chen, Wei-Han Zhang, Xin-Zu Chen, Kun Yang, Zong-Guang Zhou, Jian-Kun Hu

“…Baseline characteristics between two groups were well balanced. The operation time of RAG was longer than that of LAG (333.1±61.4 min vs. 290.6±39.0 min, p=0.001), and the estimated blood loss was 62.4±41.2 ml in the RAG group and 77.7±32.3 ml in the LAG group (p=0.005), respectively. …”
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Mycotoxilogical monitoring. Part 2. Wheat, barley, oat and maize grain by G. P. Kononenko, A. A. Burkin, Ye. V. Zotova

“…High prevalence of alternariol and emodin known as “diarrhea factor” as well as maize grain contamination with mycophenolic acid (mycotoxin having an immunosuppressive effect) are for the first time reported in this paper. These data support the need of their introduction in the group of regulated substances significant for public health. …”
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Effort-reward imbalance and health outcomes in emergency nurses: the mediating role of work–family conflict and intrinsic effort by Le Tong, Le Tong, Ling Zhu, Ling Zhu, Hao Zhang, Hao Zhang, Luying Zhong, Luying Zhong, Dongmei Diao, Dongmei Diao, Xiaoli Chen, Xiaoli Chen, Jianna Zhang, Jianna Zhang

“…Future research should focus on longitudinal studies to assess the effectiveness of these interventions over time.…”
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Short- But Not Long-Term Effects of Creep Feeding Provided to Suckling Piglets by María Romero, Ana Heras-Molina, María Muñoz, Luis Calvo, José Ignacio Morales, Ana Isabel Rodríguez, Rosa Escudero, Clemente López-Bote, Cristina Óvilo, Álvaro Olivares

“…Feces samples from the rectum were obtained at three time points (three days prior weaning, a week after weaning, and before the slaughtering of the pigs). …”
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Exploring under-five child malnutrition in Bangladesh: Analysis using the Extended Composite Index of Anthropometric Failure (ECIEF) by Farzana Akhter Bornee, Mohammad Rocky Khan Chowdhury, Badrun Naher Siddique, Baki Billah, Farjana Akter, Md Nazmul Karim

“…Continuous monitoring of the ECIAF over time would facilitate tracking changes in the prevalence of different forms of malnutrition, helping to plan interventions and assess the effectiveness of interventions aimed at addressing both undernutrition and overweight. …”
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