Early health technology assessment of tongue swab for non-sputum based pulmonary tuberculosis diagnosis in ThailandResearch in context by Langming Mou, Teerawat Wiwatpanit, Apiwat Piriyapol, Puwadol Chawengkul, Janjira Thaipadungpanit, Puttarin Kulchaitanaroaj, Yot Teerawattananon, Yi Wang

“…An early health economic model evaluated the cost-effectiveness of two innovative strategies: tongue swab with Loop-Mediated Isothermal Amplification (LAMP) and tongue swab with real-time polymerase chain reaction (RTPCR). The TPP outlines three target levels to guide innovators in designing effective clinical studies. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…Corrected calcium was defined as follows: corrected calcium = total calcium - 0.707*(albumin - 3.4). During this time frame, 1628 patients underwent nephrectomy (partial or radical) for renal masses, 91 (5.6%) of whom had metastatic disease. …”
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Epigenetic «probes» for lung cancer monitoring: LINE-1 methylation pattern in blood- circulating DNA by A. A. Ponomaryova, Е. Y. Rykova, N. V. Cherdyntseva, A. A. Bondar, A. Y. Dobrodeev, A. A. Zavyalov, S. A. Tuzikov, L. O. Bryzgalov, T. I. Merkulova, V. V. Vlassov, P. P. Laktionov

“…Concentrations of methylated LINE-1 region 1 copies (LINE-1met) were assayed by real-time methylation-specific PCR. In order to normalize the LINE-1 methylation level, the LINE-1 region 2 concentration was evaluated, which was independent of the methylation status (LINE-1Ind). …”
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Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus by YU Qin, XU Tingting, YANG Hao, ZHAO Lei

“…[Methods] From January to December 2022, 219 samples positive for hepatitis B surface antigen (HBsAg), 142 occult hepatitis B virus infection (OBI) samples (HBV group) and 873 samples tested negative (control group) were collected. 361 samples were further tested with viral load assay and serological testing for five serological markers (HBsAg, HBsAb, HBeAg, HBeAb and HBcAb), and the DNA load was measured using real time fluorescence quantitative PCR. Commercially available enzyme-linked immunosorbent assays (ELISA) were used for the detection of anti-HEV IgG, anti-HEV IgM and HEV antigen (Ag). …”
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Dim blue light at night worsens high-fat diet-induced kidney damage via increasing corticosterone levels and modulating the expression of circadian clock genes by Wenji Ren, Zixu Wang, Yulan Dong, Jing Cao, Ting Gao, Qingyun Guo, Yaoxing Chen

“…Furthermore, dBL increased BAX protein levels and decreased BCL2 protein levels. At the same time, dBL affected the Keap1/Nrf2/HO-1 signaling pathway, elevating KEAP1 and decreasing NRF2 and HO-1 protein levels. …”
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Association between beta‐blocker atenolol use and prostate cancer upgrading in active surveillance1 by Ali H. Zahalka, Ethan Fram, Evan Garden, Lauren Howard, Emily Wiggins, Mustufa Babar, Jay Annam, Allison Reagan, Benjamin Eilender, Amanda deHoedt, Stephen J. Freedland, Ash Tewari, Kara L. Watts

“…Cox proportional hazard regression models were used to determine the associations between atenolol use and risk of upgrading with time, on a per‐examination basis. Results A total of 467 men with initial GG ≤ 2 were included. …”
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Construction and application of optimized model for mine water inflow prediction based on neural network and ARIMA model by Xiaoyu Gong, Bo Li, Yu Yang, MengHua Li, Tao Li, Beibei Zhang, Lulin Zheng, Hongfei Duan, Pu Liu, Xin Hu, Xin Xiang, Xinju Zhou

“…In order to better predict the amount of water surging in mines and to provide an important basis for mine water damage prevention work, based on the time series data of mine water influx from January 2020 to February 2023 in Northern Guizhou Province Longfeng Coal Mine, the BP-ARIMA prediction model was established by combining the BP neural network model and ARIMA autoregressive sliding average model, It also predicted the mine influx for a total of 6 months from July 2022 to February 2023, and compared the prediction results with four models, namely, BP neural network model, ARIMA autoregressive sliding average model, traditional method of Large well method, and GM(1,1) grey model, and used the absolute relative error as the calculation of model accuracy. …”
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اثر تمرین شنا بر بیان ژن‌های هیپوکامپی mir-23b و mir-let-7 مرتبط با درد، در موش‌های صحرایی نژاد ویستار مبتلا به پارکینسون... by رضا زین العبادی, مهرزاد مقدسی, محمدامین عدالت منش, مهدی نورا

“…بیان ژن  های mir-23b و mir-let-7 در بافت هیپوکامپ، با روش Real Time-PCR اندازه‌گیری شد. تغییرات بیان ژن با استفاده از آزمون تحلیل واریانس یک راهه و آزمون تعقیبی LSD در سطح معنی‌داری 05/0>p تجزیه و تحلیل شدند. …”
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Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin by A. Valle, J. Sastre-Serra, C. Pol, A. M. Miró, J. Oliver, P. Roca

“…Methods: We used two-dimensional gel electrophoresis (2-DE) and matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) to identify proteins affected by leptin. …”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Cell proliferation assay, beta galactosidase staining, immunocytochemistry, and real-time PCR techniques were applied. Results. Cell proliferation assay showed no difference between early and late passages while senescence markers p16 and p21 were considerably increased in late passage. …”
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An efficient strategy to boost photoelectrochemical water oxidation of g-C3N4 films modified with NiO as cocatalyst by Lingling Bi, Jiahao Zhan, Wenhao Zhang, Zhenzhou Wu, Weichuan Xu, Xiaobo Liang, Lijing Zhang, Bin Yan, Chunyi Xu

“…As such, the NiO-60s (the deposition time of NiO is 60 s) photoanode exhibits a higher photocurrent density and much negative onset potential than g-C3N4. which is of great benefit to designing effective g-C3N4 based photoanode for PEC water oxidation reaction.…”
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Model Evaluasi Usability Menggunakan Confirmatory Factor Analysis pada KRS Online by Endah Ratna Arumi, Pristi Sukmasetya, Agus Setiawan

“…Abstract Nowadays, the development of computer software systems is not just a functional analysis. At this time, the software interface has begun to become a focus in software development. …”
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Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients by Kai Bartkowiak, Parinaz Mossahebi Mohammadi, Paula Nissen, Stefan Werner, David Agorku, Antje Andreas, Maria Geffken, Sven Peine, Karl Verpoort, Thomas M. Deutsch, Laura L. Michel, Andreas Schneeweiss, Verena Thewes, Andreas Trumpp, Olaf Hardt, Volkmar Müller, Sabine Riethdorf, Hartmut Schlüter, Klaus Pantel

“…In conclusion, we show, for the first time, that SUSD2 is expressed in CTCs and appears to affect key proteins in tumor progression and survival.…”
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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

“…By 2026, participants will be surveyed up to four times annually during their outpatient visits. The survey consists of 342 items across 5 domains: comorbidities (96), health behaviours (80), QoL (41), unmet needs (75) and mental health (50). …”
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Interleukin-12 Inhibits Tumor Growth and Metastasis Promoted by Tumor-Associated Mesenchymal Stem Cells in Triple-Negative Breast Cancer by Babak Jahangiri, Zahra-Soheila Soheili, Elahe Asadollahi, Mehdi Shamsara, Vahid Shariati, Alireza Zomorodipour

“…Epithelial-mesenchymal transition (EMT) marker expression was quantifiedby real-time polymerase chain reaction (RT-PCR). Cell proliferation was measured using trypan blue exclusiontechnique, while cell cycle distribution and apoptosis were assessed by flow cytometry. …”
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Resistive switching mechanisms in BiFeO3 devices with YBCO and Ag as top electrodes by Santiago Ceballos Medina, Lorena Marín Mercado, Alexander Cardona-Rodríguez, Mario Fernando Quiñonez Penagos, César Magén, Luis Alfredo Rodríguez, Juan Gabriel Ramírez

“…Ag top electrodes devices consistently exhibited higher resistance ratios ‒approximately three times larger‒ compared to YBCO devices. Furthermore, better temporal stability of HRS and LRS was observed in devices with Ag top electrodes, attributed to the differences in the Fermi energy levels between YBCO, Ag and BFO. …”
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Perfusion index as a predictor of successful PNS-guided supraclavicular block: A prospective study by Monika Gandhi, Khushboo Ranpise, Aseem Sharma, Manish Banjare

“…These metrics provide clinicians with a quick and practical tool for evaluating block efficacy in real-time, potentially improving clinical outcomes.…”
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Differential coping capacities underlie the overall resistance of temperate seagrasses to herbivory by J. Boada, T. M. Smith, A. M. Ricart, T. Alcoverro, M. Pérez, J. Romero, N. Sanmartí, Y. Ontoria, M. Pierrejen, R. Arthur, D. Alonso, M. P. Adams, F. Rossi

“…We experimentally tested in the field the responses of three seagrass species with distinct life history traits to increasing intensities of herbivory over time. Specifically, we assessed structural responses (i.e., canopy height and shoot density) to reflect the ecosystem state. …”
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Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor by Toru Momozane, Eriko Fukui, Soichiro Funaki, Makoto Fujii, Yuhei Kinehara, Emiko Ito, Shigeru Miyagawa, Yuko Ohno, Yoshiki Sawa, Meinoshin Okumura, Yasushi Shintani

“…First, the murine iPSC line 20D-17 was induced to differentiate into ATII over a period of 26 days (days 0-26) using previously reported embryoid body seeding and stepwise differentiation methods. mRNA expressions of differentiation markers including surfactant protein C (Sftpc) were confirmed by real-time reverse transcription-polymerase chain reaction (RT-PCR) results, and 17% of the cells were shown positive for prosurfactant protein C (proSPC) in flow cytometry analysis. …”
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Functional Characteristics and Lipid Lowering Activity of Auricularia heimuer Soluble Dietary Fiber by Xueyu SHANG, Heriban MEI, Ling SU, Qi WANG

“…In addition, HSDF with a concentration of 2.0 mg·mL−1 had a 75% inhibition rate of pancreatic lipase, and had good lipid-lowering activity in vitro. At the same time, HSDF could significantly (P<0.05) improve the organ index of HFD mice, improve the lipid accumulation, inflammatory cell infiltration in the liver and adipocyte enlargement in adipose tissue of HFD mice, and improve the cell area of white adipose tissue of epididymis by more than 50%, which had a good lipid-lowering effect in vivo. …”
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