Shaping Ability of XP Endo Shaper File in Curved Root Canal Models by Abdulmohsen Alfadley, Abdalrhman Alrajhi, Hamad Alissa, Faisal Alzeghaibi, Lubna Hamadah, Khalid Alfouzan, Ahmed Jamleh

“…Images of the canals were obtained before and after instrumentation using a stereomicroscope to measure the amount of removed resin from both the inner and outer curvature sides at apex (0 mm) and 3 mm and 6 mm from the apex. The shaping time was calculated. The data were statistically analyzed by the independent t-test at 5% significance level. …”
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Perceived benefits and challenges one year after receiving brief therapy in a district psychiatric centre. An exploration of patients' and GPs' experiences: A qualitative study. by Hilde V Markussen, Lene Aasdahl, Petter Viksveen, Marit B Rise

“…The GPs' experiences are included in each condensed patient story to challenge and elaborate on relevant aspects.<h4>Conclusion</h4>Time-limited brief therapy was experienced as beneficial for patients with moderate affective and anxiety disorders but was experienced as unsuitable for those with more severe conditions. …”
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miR-182 promoter hypermethylation predicts the better outcome of AML patients treated with AZA + VEN in a real-world setting by Yilan Xu, Danyang Li, Na Wang, Bei Ge, Chen Meng, Min Zhao, Zihan Lin, Min Li, Yigang Yuan, Yue Cai, Liuzhi Shi, Shenmeng Gao, Haige Ye

“…However, some AML patients (11.7%) still presented low miR-182 promoter methylation (< 10%). The average time to obtain CR/CRi was shorter in AML patients with miR-182 promoter hypermethylation than AML with hypomethylation. …”
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Totally robotic total gastrectomy with D2 lymphadenectomy for gastric cancer via da Vinci Xi platform: Technical details and perioperative outcomes by Chengcai Liang, Jianrong Guo, Guoming Chen, Zhiwei Zhou, Shuqiang Yuan

“…Results: With an estimated blood loss of 100 ​ml, the operation lasted 210 ​min, including an anastomosis time of 36 ​min. During a postoperative hospital stay of 7 days, the patient started liquid diet after the removal of gastric tube on the third day. …”
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Impact of the Late Miocene Cooling on the loss of coral reefs in the Central Indo-Pacific by B. F. Petrick, L. Reuning, M. Pfeiffer, G. Auer, L. Schwark

“…However, a lack of proxy data prevents an understanding of climatic changes during this time. Here, we present a TEX<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M1" display="inline" overflow="scroll" dspmath="mathml"><mrow><msubsup><mi/><mn mathvariant="normal">86</mn><mi mathvariant="normal">H</mi></msubsup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="11pt" height="17pt" class="svg-formula" dspmath="mathimg" md5hash="2a07f66c340e5ca419639b2784f7d244"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="cp-21-405-2025-ie00001.svg" width="11pt" height="17pt" src="cp-21-405-2025-ie00001.png"/></svg:svg></span></span>-based sea surface temperature (SST) record for the Coral Sea, suggesting that the LMC is present across the Central Indo-Pacific. …”
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Phosphate-modified CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells by A. A. Ostanin, O. Y. Leplina, E. A. Burakova, T. V. Tyrinova, A. A. Fokina, A. S. Proskurina, S. S. Bogachev, D. A. Stetsenko, E. R. Chernykh

“…The stimulating effect of CpG-ODN at a dose of 1.0 μg/ml was comparable (for D-SL03, D-SL03M, SD-101) with or exceeded (for SD-101M) the effect of LPS at a dose of 10 μg/ml. At the same time, IFN-DCs were characterized by greater sensitivity to the action of CpG-ODNs than IL4-DCs. …”
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Research on smoke diffusion and evacuation routes of mine fires with complex roadway networks by Menghui Xiao, Cuifeng Du, Yuan Wang, Jiuzhu Wang, Baomeng Chang

“…Miners in the working face near the fire zone had an optimal evacuation window of only 3 min, and the optimal evacuation times varied for different mining levels and sublevels. …”
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Reverse Shoulder Arthroplasty Baseplate Stability Is Affected by Bone Density and the Type and Amount of Augmentation by Daniel Ritter, Patric Raiss, Patrick J. Denard, Brian C. Werner, Manuel Kistler, Celina Lesnicar, Micheal van der Merwe, Peter E. Müller, Matthias Woiczinski, Coen A. Wijdicks, Samuel Bachmaier

“…Micromotion correlated with the subchondral bone density in the BIO-RSA group (r = −0.63, <i>p</i> = 0.036), but not in the MA-RSA (<i>p</i> > 0.178) or reference (<i>p</i> > 0.117) groups. Conclusions: Time-zero baseplate implant fixation is more variable with BIO-RSA and correlates with bone density. …”
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An examination of ankle joint position sense, postural control and associated neuromuscular deficits in patients with plantar fasciitis: a cross-sectional analysis with advanced bi... by Shaker Hassan S. Alshehri, Mastour Saeed Alshahrani, Saeed Y. Al Adal, Faisal M. Alyazedi, Hani Hassan Alnakhli, Ravi Shankar Reddy

“…Gait parameters (step length, cadence, stance time) were captured via 3D motion capture. Pain catastrophizing, physical activity, and quality of life were evaluated using validated questionnaires (PCS, IPAQ, FHSQ). …”
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H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux by Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Jinfeng Zhao, Yajun Zhai, Yajun Zhai, Li Yuan, Li Yuan, Li Yuan, Li Yuan

“…The hns-deleted mutant EΔhns, the hns-complemented strain EΔhns/phns and the hns-overexpressed strain E/phns were derivatives of Escherichia coli ATCC 25922, the susceptibility of which were assessed by the broth microdilution method and time-kill curves assays. We found that the MICs for strain EΔhns against gentamicin and amikacin were significantly decreased by 8–16 folds in contrast to E. coli ATCC 25922. …”
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Establishment of Fermentation Kinetic Model of Streptococcus thermophilus JM108 by Wen SUN, Baolei LI, Baochao HOU, Weilian HONG, Jian HE, Chao LIANG, Yu ZHANG, Chaoxin MAN, Yujun JIANG, Ling GUO

“…This study examined the growth and metabolism of Streptococcus thermophilus JM108 to establish a time-varying model that simulated the dynamics of bacterial growth, product synthesis, and substrate consumption. …”
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Contrasting seasonal patterns in particle aggregation and dissolved organic matter transformation in a sub-Arctic fjord by M. G. Digernes, Y. V. Bodur, M. Amargant-Arumí, O. Müller, J. A. Hawkes, S. G. Kohler, U. Dietrich, M. Reigstad, M. L. Paulsen

“…We studied the seasonal transition of DOM and POM pools and their drivers in a sub-Arctic fjord by means of monthly environmental sampling and by performing experiments at selected time points. For the experiments, surface water (5 m) was either pre-filtered through a GF/F filter (0.7 <span class="inline-formula">µ</span>m) or left unfiltered, followed by 36 h incubations. …”
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Global seroprevalence of Toxoplasma gondii in pregnant women: a systematic review and meta-analysis by Nader Salari, Avijeh Rahimi, Hosna Zarei, Amir Abdolmaleki, Shabnam Rasoulpoor, Shamarina Shohaimi, Masoud Mohammadi

“…Initial searching was conducted using MeSH (Medical Subject Headings)-based keywords with no time limitation (by August 1, 2024). Collected papers were transferred to Citation Management Software (EndNote). …”
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Long-term neuropsychologic outcome of pre-emptive mTOR inhibitor treatment in children with tuberous sclerosis complex (TSC) under 4 months of age (PROTECT), a two-arm, randomized,... by Jan H. Driedger, Julian Schröter, PROTECT-Study Group, Steffen Syrbe, Afshin Saffari

“…It has thus been hypothesized, that the critical time window for mTOR inhibitors may lie in early infancy, before TSC-related symptoms such as early-onset epilepsy and infantile spasms as sign of disruptive brain maturation occur. …”
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Penerapan Algoritma Deep Learning Convolutional Neural Network Dalam Menentukan Kematangan Buah Jeruk Manis Berdasarkan Citra Red Green Blue (RGB) by Budi Yanto, Erni Rouza, Luth Fimawahib, B.Herawan Hayadi, Rinanda Rizki Pratama

“…Observations in this way have several weaknesses, namely the presence of human visual limitations, being influenced by the psychological condition of the observations and taking a long time, especially for large plantations. For this reason, an algorithm is needed to determine sweet oranges with a computerized system created using the Convolutional Neural Network (CNN) algorithm, which is one of the deep learning algorithms, which is the development of Multilayer Perceptron (MLP), which is able to process data in two-dimensional form, for example. …”
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De Novo Donor-Specific HLA Antibody Development and Peripheral CD4+CD25high Cells in Kidney Transplant Recipients: A Place for Interaction? by Josefina Alberu, Maria Inés Vargas-Rojas, Luis E. Morales-Buenrostro, Jose C. Crispin, Roxana Rodríguez-Romo, Norma O. Uribe-Uribe, Gabriel Carrasco, Diana Gómez-Martín, Jorge Alcocer-Varela

“…The differences in Treg numbers observed at the late time point may reflect better immune acceptance of the graft and may be associated to long-term effects. …”
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Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids by Janesh Pillay, Antine W. Flikweert, Matijs van Meurs, Marco J. Grootenboers, Simone van der Sar-van der Brugge, Peter H. J. van der Voort, Morten A. Karsdal, Jannie M. B. Sand, Diana J. Leeming, Janette K. Burgess, Jill Moser

“…Non-survivors displayed rising levels of collagen degradation and synthesis markers over time, whereas survivors had stable or declining levels. …”
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Prediksi Detak Jantung Berbasis LSTM pada Raspberry Pi untuk Pemantauan Kesehatan Portabel by Ahmad Foresta Azhar Zen, Eko Sakti Pramukantoro, Kasyful Amron, Viera Wardhani, Putri Annisa Kamila

“…The implementation of inference on the Raspberry Pi also demonstrates good performance, with an average inference time of 4.82 seconds for processing 100 data points and a memory usage of 134.8MB. …”
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A novel CFD-MILP-ANN approach for optimizing sensor placement, number, and source localization in large-scale gas dispersion from unknown locations by Yiming Lang, Michelle Xin Yi Ng, Kai Xiang Yu, Binghui Chen, Peng Chee Tan, Khang Wei Tan, Weng Hoong Lam, Parthiban Siwayanan, Kek Seong Kim, Thomas Shean Yaw Choong, Joon Yoon Ten, Zhen Hong Ban

“…The Internet of Things (IoT) enables online real-time gas concentrations, but its capability to predict leak sources accurately remains a challenge. …”
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Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept by Jingjing Li, Yanzhao Zhang, Mingyue Wei, Junjie He, Huifeng Ma, Zilong Chen, Jiajia Duan, Chuanxin Liu

“…Methods: Using the toxicological evidence chain (TEC) as a research method, our team constructed, for the first time, a rat model in which podophyllotoxin caused ovarian damage and investigated the mechanism of the toxic effects of podophyllotoxin on the ovaries. …”
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