Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease by Yue Xu, Yue Xu, Durong Chen, Meiqi Dong, Yun Zhang, Yun Zhang, Hongmei Yu, Hongmei Yu, Hongmei Yu, Yanqing Han, Yanqing Han, Yanqing Han

“…ObjectiveTo investigate the bidirectional relationship between depression and activities of daily living (ADL) in Parkinson’s disease (PD) patients and explore the mediating role of cognitive function over time.MethodsData from 892 PD patients from the Parkinson’s Progression Markers Initiative (PPMI) database were included in this study, and depression, cognitive function, and ADL were measured using the Geriatric Depression Scale (GDS-15), Montreal Cognitive Assessment Scale (MoCA), and Unified Parkinson’s Disease Rating Scale, Part II (UPDRS II) respectively. …”
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Nomogram based on the log odds of negative lymph node/T stage can predict the prognosis of patients with colorectal cancer: a retrospective study based on SEER database and externa... by Xiaochun Chen, Yimin Li, Boyong Cai, Mengli Zheng, Zhicao Chen, Canxin Zhong, Guiquan Chen

“…The performance of the nomogram was comprehensively assessed via the time-dependent receiver operating characteristic curve, concordance index (C-index), calibration curve and decision curve analysis (DCA) comprehensively. …”
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Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Techniques such as biochemical assays, Enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting, and immunofluorescence labeling were employed to detect changes in nitric oxide (NO), lactate dehydrogenase (LDH), inflammatory markers, and components of the cartilage matrix in chondrocytes. …”
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Efficacy and safety of edoxaban in patients with chronic thromboembolic pulmonary hypertension: protocol for a multicentre, randomised, warfarin-controlled, parallel group trial -... by Keiichi Fukuda, Satoshi Yasuda, Hiroyuki Tsutsui, Toyoaki Murohara, Kohtaro Abe, Koichiro Tatsumi, Junji Kishimoto, Yu Taniguchi, Yuichi Tamura, Koji Todaka, Shun Minatsuki, Kazuya Hosokawa, Yuko Kobayakawa, Takumi Inami, Nobutaka Ikeda

“…The anticoagulant activity of warfarin is affected by food and drug interactions, requiring regular monitoring of prothrombin time. The lability of anticoagulant effect often results in haemorrhagic and thromboembolic complications. …”
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Ethnobotanical studies on rice landraces under on-farm conservation in Xishuangbanna of Yunnan Province, China by Fei Wang, Tao Sun, Shuai Yu, Chunhui Liu, Zhuo Cheng, Jianxin Xia, Longzhi Han

“…The Dai, primary cultivators of glutinous rice with higher diversity, intertwine their traditional ethnic culture with the conservation of glutinous rice resources. At the same time, the preserving glutinous rice resources promotes the inheritance of Dai ethnic culture. …”
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Interleukin 10 Plays an Important Role in Neonatal Rats with Hypoxic-Ischemia Associated with B-Cell Lymphoma 2 and Endoplasmic Reticulum Protein 29 by Xue Bai, Liu-Lin Xiong, Chang-Le Fang, Hao-Li Zhou, Lu-Lu Xue, Yue Hu, Qing-Jie Xia, Jia Liu, Jun-Yan Zhang, Ting-Hua Wang, Si-Jin Yang

“…The expression of IL-10 in the cortex, hippocampus, and lung tissues was measured with immunohistochemistry, real-time quantitative polymerase chain reaction (RT-qPCR), and western blot (WB). …”
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Cultivatable Bacteriota of Chronic Wound of Patients with Diabetic Foot Syndrome with Critical Limb Ischemia Based on Wound Biopsy in Peri-Revascularization Period by Syedah Sarah Hussaini, Fran Dominic Grubesa, Mateusz Gajda, Martyna Schönborn, Katarzyna Bogucka, Mikołaj Maga, Paweł Maga, Jadwiga Wójkowska-Mach

“…The blood supply to the limb was assessed with laboratory tests and two time-point qualitative cultures using a wound biopsy. …”
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Meta-analysis and Trial Sequential Analysis for Therapeutic Eefficacy and Safety of Acupotomy and Acupuncture for Cervical Spondylotic Radiculopathy by Renpan ZHANG, Zhongbiao XIU, Jing LIU, Bin CHEN, Hong LIU, Hongjia ZHAO

“…Clinical randomized controlled trials(RCTs)of acupotomy versus acupuncture with/without additional treatment for cervical spondylotic radiculopathy patients would be searched by two reachers independently. The time limitation was from the commencement of each database to 31st October 2018. …”
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Optomechanical energy enhanced BF-QEPAS for fast and sensitive gas sensing by Weilin Ye, Linfeng He, Weihao Liu, Zhile Yuan, Kaiyuan Zheng, Guolin Li

“…Traditional beat frequency quartz-enhanced photoacoustic spectroscopy (BF-QEPAS) are limited by short energy accumulation times and the necessity of a decay period, leading to weaker signals and longer measurement cycles. …”
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Understanding the experiences of birthing care during COVID-19: A qualitative systematic review by Danielle Macdonald, Kristen Bigelow-Talbert, Amanda Ross-White, Erna Snelgrove-Clarke, Leah Sookhoo

“…Background: The Covid-19 pandemic was a challenging time for people who sought health care and for health care providers. …”
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Possible linking and treatment between Parkinson’s disease and inflammatory bowel disease: a study of Mendelian randomization based on gut–brain axis by Beiming Wang, Xiaoyin Bai, Yingmai Yang, Hong Yang

“…LRRK2 and RAB29 were reported to be pleiotropic genes, and RAB29 and HLA-DQA2 were reported for the first time as potential drug targets. Conclusions This study established a reliable causal relationship, possible shared drug targets and common pathogenesis pathways of two diseases, which had important implications for intervention and treatment of two diseases simultaneously.…”
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Response surface methodology for the design of malachite green dye removal by γ-Fe2O3 dispersed on reduced graphene oxide sheets by Liu Zhu, Anam Sana, Muhammad Tariq Qamar, Ali Bahadur, Guocong Liu, Mohammad Aslam, Ammar Zidan, İsmail Seçkin Çardaklı, Shahid Iqbal, Sajid Mahmood, Muhammad Saad, Khalid M. Alotaibi

“…The optimal adsorption parameters obtained from the within-range numerical optimization based on 0.923 Derringer’s desirability function were 200 mg/100 mL dose, 80 ppm dye solution, 7.99 pH and 112.68 min. contact time for ~ 90% MG dye removal and 40.64 mg/g adsorption capacity (qm) by rGO/γ-Fe2O3. …”
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Aux origines gauloises de Tours (Indre-et-Loire) : état des connaissances by Sandrine Linger-Riquier

“…A number of difficulties or limitations were present during the excavation of this material, including: the depth at which the Gallic remains reside (some 3 to 7 m in certain areas), the small size of the opened spaces, safety concerns, the water table level, the available time for investigation, and historical prejudices. …”
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Novel MOF-based vanadium and 2,2 -bipyridine-4,4 -dicarboxylic acid as phenomenal dye adsorbent and antimicrobial agent by Baraa Mohammed Yaseen, Farag M. A. Altalbawy, Farag M. A. Altalbawy, Rafid Jihad Albadr, Waam Mohammed Taher, Mariem Alwan, Mahmood Jasem Jawad, Hiba Mushtaq, Khursheed Muzammil, Ahmed Hussein Zwamel, Ahmed Hussein Zwamel, Ahmed Hussein Zwamel

“…In the investigation of CR absorption activity, several factors such as concentration of V/BP-MOF, pH, time, and temperature were investigated. Antimicrobial evaluations were carried out on Common bacterial strains in wastewater and values of MIC (minimum inhibitory concentration) and MBC (Minimum Bactericidal Concentration) were reported. …”
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Protocol on establishing a prospective enhanced surveillance of vaccine preventable diseases in residential aged care facilities in Central Queensland, Australia: an observational... by Mohammad Rashidul Hashan, Robert Booy, Michael Kirk, Gulam Khandaker, Gwenda Chapman, Jacina Walker, Sonya Jayne Davidson, Jill Auriac, Nicolas Smoll, Delwar Akbar

“…The increasing burden of emerging and existing VPDs (eg, COVID-19, influenza, pneumococcal, pertussis and varicella-zoster) necessitates the establishment of an active enhanced surveillance system to provide real-time evidence to devise strategies to reduce the burden of VPDs in RACFs.Method and analysis This study proposes a prospective active enhanced surveillance that will be implemented in RACFs across the Central Queensland (CQ) region. …”
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5G Networks Security Mitigation Model: An ANN-ISM Hybrid Approach by Rafiq Ahmad Khan, Habib Ullah Khan, Hathal Salamah Alwageed, Hussein Al Hashimi, Ismail Keshta

“…In the third phase, we employed a hybrid approach integrating ANN for real-time threat detection and risk assessment and utilizing ISM to analyze the relationships between security threats and vulnerabilities, creating a structured framework for understanding their interdependencies. …”
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A case of hypophysitis after COVID-19 vaccination with a detection of anti-pituitary antibody, with review of literature by Chika Kyo, Tomoko Kobayashi, Shintaro Iwama, Rieko Kosugi, Fumikazu Sawabe, Ryo Hayafusa, Yuki Sakai, Tatsuo Ogawa, Masato Kotani, Tatsuhide Inoue, Hiroshi Arima, Hiroyuki Ariyasu

“…Unlike previous cases, our patient has partial recovery from pituitary insufficiency, and his pituitary function gradually improved over time. Anti-pituitary antibodies (APAs) against corticotrophs, thyrotrophs, gonadotrophs, and folliculo stellate cells (FSCs) were detected in serum samples taken 3 months after onset. …”
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Towards a sustainable set of European Core Health Indicators (ECHI) by Mariken J. Tijhuis, Eveline A. van der Wilk, Sarka Dankova, Angela Fehr, Silvia Ghirini, Mika Gissler, Romana Haneef, Heidi Lyshol, Emanuele Scafato, Stefanie Seeling, Hanna Tolonen, Thomas Ziese, Irisa Zīle-Velika, Peter W. Achterberg

“…As the ECHI set was defined more than ten years ago, it is time to review its current needs and readiness for the future. …”
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Development and Validation of an UHPLC-MS/MS Method for Quantification of DMAG in Rat Plasma and Its Application in a Preliminary Pharmacokinetic Study in Thrombocytopenia Rats by Yan Li, Yuqing Wang, Zhiqiang Zhao, Yunxia Li, Cheng Peng, Jianming Wu

“…DMAG and hispidulin (internal standard, IS) were separated on an Acquity Shim-pack GIST column using 0.1% formic acid in water and acetonitrile as the mobile phase with a total run time of 5 min and gradient elution at a flow rate of 0.3 mL/min. …”
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A developed TaqMan probe-based qPCR was used to quantify the distribution of AMDV in various tissues of infected mink and its prevalence in northern China by Zaixing Yang, Zaixing Yang, Yifan Li, Yuxuan Jiang, Yuxuan Jiang, Jingqi Wu, Zhenhong Guan, Junwei Ge, Lili Zhao

“…In this study, we developed a TaqMan probe-based real-time PCR technology (TaqMan-qPCR) for the specific, sensitive, and reproducible detection and quantification of AMDV in mink tissues by the VP2 gene, achieving detection limits as low as 1.69 × 101 copies/uL of plasmid DNA and 8.50 × 10−3 ng/uL of viral DNA, and the established TaqMan-qPCR assay is 100 times more sensitive than PCR. …”
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