Increasing Access to Mental Health Supports for 18- to 25-Year-Old Indigenous Youth With the JoyPop Mobile Mental Health App: Study Protocol for a Randomized Controlled Trial by Angela MacIsaac, Teagan Neufeld, Ishaq Malik, Elaine Toombs, Janine V Olthuis, Fred Schmidt, Crystal Dunning, Kristine Stasiuk, Tina Bobinski, Arto Ohinmaa, Sherry H Stewart, Amanda S Newton, Aislin R Mushquash

“…Linear mixed modeling will be used to analyze change in outcomes over time as a function of condition assignment, while a cost-consequence analysis will be used to evaluate the association between app use and service use. …”
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Obstetric outcomes in breastfeeding women in the first hour of delivery before and during the COVID-19 pandemic by Ana Paula Vieira Faria, Thales Philipe Rodrigues da Silva, Mery Natali Silva Abreu, Maria Albertina Canastra, Ana Clara Fernandes, Eunice Francisca Martins, Fernanda Marçal Ferreira, Fernanda Penido Matozinhos

“…Regarding the pandemic period, we observed that women who underwent cesarean section reduced, on average, 0.61 times the chance of breastfeeding after delivery (p = 0.027), women who had a newborn weighing less than 2500 g reduced, on average, 0.29 times the chance of breastfeeding after delivery (p = 0.031) and women who had a newborn with complications after delivery reduced, on average, 0.05 times the chance of breastfeeding after delivery (p < 0.001). …”
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Doctor, what is my risk of bleeding after cardiac surgery while on combined anticoagulant with antiplatelet therapy? A validated nomogram for risk assessment by Haolong Han, Haolong Han, Hang Xu, Hang Xu, Jifan Zhang, Weihui Zhang, Yi Yang, Xia Wang, Li Wang, Dongjin Wang, Weihong Ge

“…Various models were developed, validated and evaluated by using methods including ROC curves, calibration curves, the Hosmer-Lemeshow test, net reclassification improvement (NRI), integrated discrimination improvement (IDI) index, decision curve analysis (DCA) and clinical impact curves (CIC).ResultsMod2 showed the best performance (AUC of validation set = 0.863) which consists of 8 independent predictive factors (gender, age &gt; 65 years, diabetes, anemia, atrial fibrillation, cardiopulmonary bypass time, intraoperative bleeding and postoperative drainage), with a significantly higher AUC compared to Mod1 (only preoperative factors) and Mod3 (the HAS-BLED scoring model). …”
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Forestry features of regionalization of forest reproductive material by Oleg Danchuk, Vasyl Blystiv, Zinovii Yurkiv, Vitaly Vovchanskyi

“…The most detailed regionalization has been developed in most countries for European beech, Scots pine, silver fir, and Norway spruce – forest-forming species that have a wide distribution area in the European part of the continent and are, at the same time, most widely represented in Ukraine. The regionalization scheme of forest reproductive material (FRM) proposes the allocation of silvicultural districts (the basis is silvicultural zoning and typification of forest crops), forest seed districts - regions of distribution (recognition and accounting of the basic forest material and the boundaries of the FRM distribution), regions (districts) of origin (accounting of objects of the permanent forest seed base, producers and suppliers of FRM) and the origin of autochthonous species (by codes of origin). …”
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MLinvitroTox reloaded for high-throughput hazard-based prioritization of high-resolution mass spectrometry data by Katarzyna Arturi, Eliza J. Harris, Lilian Gasser, Beate I. Escher, Georg Braun, Robin Bosshard, Juliane Hollender

“…For each analyzed HRMS feature, MLinvitroTox generates a 490-bit bioactivity fingerprint used as a basis for prioritization, focusing the time-consuming molecular identification efforts on features most likely to cause adverse effects. …”
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Wound-healing activity of solvent fractions and antiinflammatory activity of crude extract and solvent fractions of Acokanthera schimperi Schweinf (Apocynaceae) leaves in mice mode... by Workineh Woldeselassie Hammeso, Tesfaye Yimer, Getnet Tadege, Wakuma Wakene Jifar, Dejen Nureye

“…The excision model was utilized to estimate wound contraction and epithelization time, whereas the incision model was utilized to measure tensile strength. …”
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Health-related Quality of Life and Exercise Capacity in Double Lung Transplant Recipients With Baseline Lung Allograft Dysfunction by Alisha Rullay, BSc, Karina Kaur, BSc, Jennifer Holman, PT, Laura C. van den Bosch, MD, Justin G. Weinkauf, MD, Jayan Nagendran, MD, PhD, Rhea A. Varughese, MD, Alim S. Hirji, MD, Dale C. Lien, MD, Jason C. Weatherald, MD, Kieran M. Halloran, MD

“…We defined BLAD as a failure of both forced expiratory volume in 1 s and forced vital capacity to reach ≥80% predicted of a healthy reference population’s lung function on 2 consecutive tests ≥3 wk apart at any time point posttransplant. We tested the relationship between BLAD status and SF-36 physical component summaries and 6MWD using least squares regression, adjusting for age at transplant, sex at birth, and primary lung disease. …”
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Preference for daily (1HP) vs. weekly (3HP) isoniazid-rifapentine among people living with HIV in Uganda by A. Musinguzi, H. E. Aschmann, J. L. Kadota, J. Nakimuli, F. Welishe, J. Kakeeto, C. Namale, L. Akello, A. Nakitende, C. Berger, A. Katamba, J. Tumuhamye, N. Kiwanuka, D. W. Dowdy, A. Cattamanchi, F. C. Semitala

“…RESULTS: Among 429 respondents (median age: 43 years, 71% female, median time on ART: 10 years), intention and confidence were rated high for both regimens. …”
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BananaImageBD: A comprehensive banana image dataset for classification of banana varieties and detection of ripeness stages in BangladeshMendeley Data by Md Hasanul Ferdaus, Rizvee Hassan Prito, Ahmed Abdal Shafi Rasel, Masud Ahmed, Md. Jahid Hassan Saykot, Shanjida Sultan Shanta, Sonali Akter, Ankan Chandra Das, Mohammad Manzurul Islam, Mahamudul Hasan, Md Sawkat Ali

“…Such ML and DL models can be leveraged to develop automated systems to determine the optimal harvest time, establish standards for quality control of bananas, develop products and marketing strategies through analysis of consumer preferences for various banana varieties and ripeness levels, and streamline the banana supply chain through improvements in harvesting, sorting, packaging, and inventory management. …”
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A Live Video Resiliency Dyadic Intervention for Persons With Dementia and Their Care-Partners Early After Diagnosis: Protocol for Open Pilot of Resilient Together for Dementia by Sydney McCage, Kristin Walker, Talea Cornelius, Robert A Parker, Kristen Dams-O'Connor, Brad Dickerson, Christine Ritchie, Ana-Maria Vranceanu, Sarah Bannon

“…The stressors experienced by dyad members at around the time of ADRD diagnosis commonly produce clinically elevated emotional distress (ie, depression and anxiety symptoms), which can become chronic and negatively impact health, relationships, and the overall quality of life. …”
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Research on the impact of land use and land cover changes on local meteorological conditions and surface ozone in the north China plain from 2001 to 2020 by Chunsheng Fang, Xinlong Li, Juan Li, Jiaqi Tian, Ju Wang

“…LULCC enhanced meteorological and chemical processes as well as vertical transport, leading to an increase in O3. At the same time, it reduced the increase in O3 through horizontal transport and dry deposition processes. …”
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Prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province: a population-based prospective study by Daya Zhang, Chen Chen, Yunqian Xie, Shuo Zhou, Da Li, Fan Zeng, Shimei Huang, Yanting Lv, Xianfeng Huang, Fengjiao Mao, Jinglei Kuang, Jin Gan, Xiaojing Xu, Shiju Chen, Runxiang Chen, Xiaodong Zhang, Sangni Xu, Minyu Zeng, Haoyue Ren, Feihu Bai

“…This study is the first to identify the incidence and associated risk factors of long COVID-19 with the longest follow-up time, providing valuable insights for the timely restoration of pre-COVID-19 health.…”
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The impact of an integrated intervention program combining drug therapy with water, sanitation, and hygiene (WASH) education on reinfection with intestinal parasitic infections amo... by Woottichai Nachaiwieng, Sangob Sanit, Nattharinee Kongta, Jassada Saingamsook, Suwit Duangmano, Sakorn Pornprasert, Pradya Somboon, Jintana Yanola

“…We demonstrated for the first time that integration of WASH education increased KAP scores and consequently significantly reduced IPI reinfection among the Karen hill tribe in northern Thailand. …”
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Validation of Immersion Precooling and Drip Sanitation Standard Operating Procedures on Weight, Temperature, Microbiological Quality, and Safety of Chicken Carcasses by Angela B.P.S. Fernandes, Clair F.S. Pereira, Hiago M. Pereira, Marco A.C. Batista, Luiz F.S. Dionisio, Amauri A. Alfieri, Bruna Alexandrino, José C. Ribeiro-Júnior

“…Salmonella serovars were determined by real-time PCR. Immersion of the carcasses in water at 9.5 (±2.89) and 2.33 (±1.30) °C in the first and second stages was sufficient to considerably reduce the carcass temperature to 5.70 and 7.41 °C at the system outlet and after dripping, respectively. …”
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Pharmacokinetics of 7,8-dihydroxyflavone in neonatal mice with hypoxia-ischemia related brain injury by Sin Yin Lim, Cameron O. Scarlett, Sefer Yapici, Peter Ferrazzano, Peter Ferrazzano, Pelin Cengiz, Pelin Cengiz

“…A nonlinear mixed-effects model was used to analyze the plasma and brain concentration-time data. A semi-quantitative approach was used to evaluate the concentrations of two active O-methylated metabolites of 7,8-DHF (8H7M-flavone and 7H8M-flavone) in both plasma and brain samples.ResultsOur PK analyses show that plasma 7,8-DHF concentrations followed a two-compartment PK model, with more than 95% eliminated by 3 h after the IP injection. …”
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Multi-modal characterisation of early-stage, subclinical cardiac deterioration in patients with type 2 diabetes by Ambre Bertrand, Andrew Lewis, Julia Camps, Vicente Grau, Blanca Rodriguez

“…Methods We quantified ECG and cardiac magnetic resonance imaging biomarkers in two matched cohorts of 1781 UK Biobank participants, with and without T2DM, and no diagnosed cardiovascular disease at the time of assessment. We performed a pair-matched cross-sectional study to compare cardiac biomarkers in both cohorts, and examined the association between T2DM and these biomarkers. …”
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Predictors of the Short‐Term Outcomes of Guillain–Barré Syndrome: Exploring Electrodiagnostic and Clinical Features by Yi‐Hsiang Chen, Chia‐Lun Wu, Wei‐Chieh Weng, Yi‐Chia Wei

“…Prompt identification of patients at a high risk of poor outcomes is crucial for timely intervention. In this study, we combined clinical data with nerve conduction study and electromyography data to identify the predictors of GBS outcomes. …”
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Preparation, Modification, Characterization and Antioxidant Activities of Apigenin Liposomes by Siyu DAI, Ying TANG, Nian LIU, Lu HE, Miao GU, Chenbo FENG, Jin REN, Zhengjie FANG

“…The optimal preparation process for AP-L included 6 mg of apigenin, an apigenin to phospholipid ratio of 1:24, a phospholipid to cholesterol ratio of 6:1, 6.3 mL of ethanol, 20 mL of phosphate buffer solution (PBS), hydration temperature 50 ℃ and ultrasonic time 20 min. The particle size of AP-L was 157.34±1.87 nm, the polydispersity index (PDI) was 0.240±0.025, and the encapsulation efficiency was 66.50%±1.00%. …”
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The White Clover Single-Copy Nuclear Gene <i>TrNAC002</i> Promotes Growth and Confers Drought Resistance in Plants Through Flavonoid Synthesis by Youzhi Zhang, Wei Fu, Qi Pu, Zhirui He, Zhou Li, Lin Liu, Xiao Ma, Yan Peng

“…Under natural drought stress, OE can survive in dry soil for a longer period of time than WT. Furthermore, OE exhibits a lower level of reactive oxygen species (ROS) level and a higher content of flavonoids than WT. …”
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Attenuated titin protein expression is associated with advanced stages of ovarian cancer by Harvey Sharma, Jaskaran Aujla, Asad Nawaz, Thabet Khasawneh, Ayesha Alvero, Robert T. Morris, Asma Basha, Laila Tutunji, Toshima Z. Parris, Khalil Helou, Ghassan M. Saed

“…Tissue samples underwent immunohistochemistry, and serum titin levels were measured using ELISA. Quantitative real-time PCR analyzed titin mRNA in cell lines, including chemosensitive, chemoresistant, and normal ovarian cells. …”
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