Low prevalence of copy number variation in pfmdr1 and pfpm2 in Plasmodium falciparum isolates from southern Angola by Denise Duarte, Francisco Manuel, Ana Dias, Esmeralda Sacato, Elsa Taleingue, Elsa Daniel, Francisco Simão, Luis Varandas, Maria Lina Antunes, Fatima Nogueira

“…Conclusions This study provides, for the first time, evidence for the presence of CNVs in the pfpm2 and pfmdr1 genes in P. falciparum isolates from southern Angola.…”
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Upstream Solar Wind Prediction up to Mars by an Operational Solar Wind Prediction System by Jingjing Wang, Yurong Shi, Bingxian Luo, Siqing Liu, Linggao Kong, Jijie Ma, Wenya Li, Binbin Tang, Aibing Zhang, Lei Li, Liqin Shi, Qiuzhen Zhong, Yanhong Chen

“…By predicting the HSEs at Earth (Mars), our model reaches a Mean Absolute Error (MAE) of 83.93 km/s (65.91 km/s) and 22.98 hr (21.65 hr) for maximum speed and arrival time prediction error, respectively. We also conduct a three‐month case study, from November 2020 to January 2021, analyzing solar wind conditions upstream of Earth, Mars, and measured by Tianwen‐1 (China's first Mars mission), for which our model is capable to predict the upstream solar wind conditions up to Mars.…”
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Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber by K. N. Naumenko, A. R. Nurislamov, K. D. Nazarov, V. S. Fishman, A. A. Popov, I. O. Petruseva, A. N. Evdokimov, O. I. Lavrik

“…Using the cDNA of the naked mole rat’s Parp1 gene, a vector was created for the expression of the target protein in Escherichia coli cell culture. For the first time, a detailed description of the procedure for the expression and purification of the recombinant protein PARP1 of the long-lived naked mole rat is presented. …”
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Hobbit: Providing Fall Detection and Prevention for the Elderly in the Real World by Markus Bajones, David Fischinger, Astrid Weiss, Daniel Wolf, Markus Vincze, Paloma de la Puente, Tobias Körtner, Markus Weninger, Konstantinos Papoutsakis, Damien Michel, Ammar Qammaz, Paschalis Panteleris, Michalis Foukarakis, Ilia Adami, Danai Ioannidi, Asterios Leonidis, Margherita Antona, Antonis Argyros, Peter Mayer, Paul Panek, Håkan Eftring, Susanne Frennert

“…To the best of our knowledge, this is the first time a multifunctional, low-cost service robot equipped with a manipulator was studied and evaluated for several weeks under real-world conditions. …”
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Therapeutic Potential of Combined 5% Lifitegrast and Tocopherol Eye Drops in Managing Inflammation and Oxidative Stress in Murine Dry Eye by Jayoung Moon, Enying Jiang, Jingting Liu, Hui Jin, Hee Su Yoon, Hoon-In Choi, Ji Suk Choi, Hong Qi, Hyeon-Jeong Yoon, Kyung Chul Yoon

“…Clinical parameters (tear volume, tear break-up time (TBUT), corneal fluorescein staining score (CFSS), tear film lipid layer grade (TFLLG)) were assessed on days 7 and 14. …”
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MENURUNNYA PENUTUR BAHASA INDONESIA SEBAGAI LINGUA FRANCA by Tato Nuryanto

“…</span> <span class="hps">There</span> <span class="hps">it</span> <span class="hps">is forgotten</span> <span class="hps">that the</span> <span class="hps">Indonesian</span> <span class="hps">actually has</span> <span class="hps">a function</span> <span class="hps">as a symbol of</span> <span class="hps">the pride of</span> <span class="hps">nationhood</span><span>,</span> <span class="hps">national identity</span><span>,</span> <span class="hps">means of</span> <span class="hps">transportation</span> <span class="hps">atarwarga</span><span>,</span> <span class="hps">interregional</span> <span class="hps">and</span> <span class="hps">intercultural</span><span>,</span> <span class="hps">as well as</span> <span class="hps">tools that</span> <span class="hps">allow</span> <span class="hps">the unification of</span> <span class="hps">the various ethnic groups</span> <span class="hps">with</span> <span class="hps">socio-cultural background</span> <span class="hps">and</span> <span class="hps">language</span> <span class="hps">of each</span> <span class="hps">into a</span> <span class="hps">unitary</span> <span class="hps">national</span> <span class="hps">Indonesia</span> <span class="hps">,</span> <span class="hps">It is very clear</span> <span class="hps">that the</span> <span class="hps">Indonesian</span> <span class="hps">association</span> <span class="hps">as</span> <span class="hps">an intermediate language</span> <span class="hps atn">(</span><span>lingua</span> <span class="hps">franca</span><span>)</span> <span class="hps">from</span> <span class="hps">time immemorial</span><span>.</span></span></p>…”
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Differences in Characteristics of Peripartum Patients Who Did and Did Not Require an Upgrade to the Intensive Care Unit: A Propensity Score Matching Study by Jennifer A. Walker, Jerry M. Yang, Saad Pirzada, Manahel Zahid, Samantha Asuncion, Amanda Tuchler, Gillian Cooper, Allison Lankford, Emad Elsamadicy, Quincy K. Tran

“…Multivariable ordinal regression analysis was used to assess the time interval to upgrade. <i>Results:</i> From 1855 peripartum patients, we analyzed 37 control and 34 upgrade patients. …”
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A Hybrid Dynamic Principal Component Analysis Feature Extraction Method to Identify Piston Pin Wear for Binary Classifier Modeling by Hao Yang, Yubin Zhai, Mengkun Zheng, Tan Wang, Dongliang Guo, Jianhui Liang, Xincheng Li, Xianliang Liu, Mingtao Jia, Rui Zhang

“…DPCA is utilized to extract dynamical vibration features by introducing time lag. Then, the dynamic principal component matrix is further decomposed by VMD to obtain intrinsic mode functions (IMFs) as finer features and is finally decomposed by SVD to compress the features, thus improving the classification efficiency based on the features. …”
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A preliminary exploration of establishing a mice model of hypoxic training by Minglu Li, Zhijie Chen, Ziyang He, Xinjuan Zhang, Yanqiu Liu, Hui Zhou, Hang Yang, Tao Liu, Xiaochuan Wang, Ran Zhang, Jiaxing Zhang

“…This study aimed to establish a mice model to determine the time point for achieving the best endurance at the lowland. …”
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Therapeutic potential of adipose-derived stem cells for diabetic foot ulcers: a systematic review and meta-analysis by Mohamed A. Abu Elainein, Mohamad Mahmoud Whdan, Mahmoud Samir, Nada G. Hamam, Mohamed Mansour, Mohamed Abdel Mohsen Mohamed, Mahmoud Mostafa Snosy, Mahmoud Ayman Othman, Ahmed Sayed Sobieh, Mahmoud Gamal Saad, Mohamed A. Labna, Salma Allam

“…Results Regarding the total healing state, five studies reported that more participants healed completely at the end of the follow-up period in the ADSCs group (Risk ratio = 1.56, 95% CI [1.32, 1.86], P < 0.00001), for the healing rate the overall effect estimate favors the ADSCs group (pooled effect estimate = 1.84, 95% CI [1.51, 2.89], P < 0.00001), and regarding the healing time the pooled mean difference of the studies demonstrated that the ADSCs group required fewer days to heal than the standard care group. …”
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The impact of implementing and sustaining the international guidelines for skin-to-skin contact in the first hour after birth in Uganda by Kajsa Brimdyr, Scovia Nalugo Mbalinda, Anna Blair, Kristin Svensson, Mike Kagawa, Melissa Reyes, Louise Racine Bastarache, Livingstone Kamoga, Edwin Kigozi, Karin Cadwell

“…Implementation of skin-to-skin contact in the first hour after birth using PRECESS resulted in significantly more time in skin-to-skin contact than pre-intervention (2 m 25 s + − 2 m 48 s vs. 57 m 51 s + −2 m 53 s p < 0.001), although breastfeeding rates in the first hour after birth were not significantly different (29% in baseline, 28% after intervention, p = 0.871). …”
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Retinal Protection of New Nutraceutical Formulation by Luca Rosario La Rosa, Veronica Pepe, Francesca Lazzara, Giovanni Luca Romano, Federica Conti, Erika Giuffrida, Claudio Bucolo, Santa Viola, Giuseppe De Pasquale, Maria Cristina Curatolo, Cristina Zappulla

“…The efficacy of Epicolin was also evaluated in DBA/2J glaucomatous mice through the use of a pattern electroretinogram (PERG), immunostaining, and real-time PCR. <b>Results:</b> Among the nutraceutical formulations tested, only Epicolin showed a significant neuroprotective effect on SH-SY5Y attributable to the synergistic action of its single ingredients. …”
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Emerging Themes in the Ecology and Management of North American Forests by Terry L. Sharik, William Adair, Fred A. Baker, Michael Battaglia, Emily J. Comfort, Anthony W. D'Amato, Craig Delong, R. Justin DeRose, Mark J. Ducey, Mark Harmon, Louise Levy, Jesse A. Logan, Joseph O'Brien, Brian J. Palik, Scott D. Roberts, Paul C. Rogers, Douglas J. Shinneman, Thomas Spies, Sarah L. Taylor, Christopher Woodall, Andrew Youngblood

“…Several “needs” emerged from the discussions regarding approaches to the study of forest ecosystems, including (1) consideration of variable spatial and temporal scales, (2) long-term monitoring, (3) development of universal databases more encompassing of time and space to facilitate meta-analyses, (4) combining field studies and modeling approaches, (5) standardizing methods of measurement and assessment, (6) guarding against oversimplification or overgeneralization from limited site-specific results, (7) greater emphasis on plant-animal interactions, and (8) better alignment of needs and communication of results between researchers and managers.…”
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Clarification of factors associated with post-artesunate delayed hemolysis (PADH): Analysis of 327 patients with severe imported Plasmodium falciparum malaria in France by Pierre-Louis Conan, Marc Thellier, Eric Kendjo, Sandrine Houzé, Rémonie Seng, Stéphane Jauréguiberry

“…Results: In the analyzed population (n = 327), 49 PADH events occurred after a median time of14 days (IQR, 13–17) after artesunate initiation. …”
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Targeting accuracy of neuronavigation: a comparative evaluation of an innovative wearable AR platform vs. traditional EM navigation by Marina Carbone, Marina Carbone, Nicola Montemurro, Nicola Montemurro, Nadia Cattari, Nadia Cattari, Martina Autelitano, Martina Autelitano, Fabrizio Cutolo, Fabrizio Cutolo, Vincenzo Ferrari, Vincenzo Ferrari, Emanuele Cigna, Emanuele Cigna, Sara Condino, Sara Condino

“…This ergonomic approach can facilitate a more intuitive understanding of spatial relationships and guidance cues, potentially reducing cognitive load and enhancing the accuracy of surgical gestures by aligning critical information with the actual anatomy in real-time. This study evaluates the benefits of a novel AR platform, VOSTARS, by comparing its targeting accuracy to that of the gold-standard electromagnetic (EM) navigation system, Medtronic StealthStation® S7®. …”
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Extent, Distribution, and Causes of Soil Acidity under Subsistence Farming System and Lime Recommendation: The Case in Wolaita, Southern Ethiopia by Fanuel Laekemariam, Kibebew Kibret

“…DAP and urea applications above 75 kg/ha lowered soil pH units by 0.56 and 0.48, respectively, <25 kg/ha while at the same time farmyard manure (FYM) at 4 t/ha raised pH by 0.75 units over the unfertilized field. …”
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The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Aslıhan Şeyda DOĞAN, Mukaddes PALA, Şenay GÖRÜCÜ YILMAZ, Ayfer BECEREN, Aydın KARABULUT, Yalçın POLAT, Hatice Kübra ELÇİOĞLU

“…Methods: Therefore, miRNAs obtained from rat heart tissue were analyzed by microarray, and twelve miRNAs (rno-miR-200c-3p, rno-miR-129-5p, rno-miR-150-3p, rno-miR-3584-5p, rno-miR-34c-3p, rno-miR-342-3p, rno-miR-466b-3p, rno-miR-466c-3p, rno-miR-31a-3p, rno-miR-15b-5p, rno-miR-196b-3p, and rno-miR-208a-5p) with changed expression levels were validated by real-time polymerase chain reaction analysis. Results: As a result of the validation, it was determined that three miRNAs (rno-miR-15b-5p, rno-miR-196b-3p, and rno-miR-208a-5p) were downregulated, one miRNA (rno-miR-200c-3p) was upregulated (p<0.05). …”
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Pregnant and Postpartum Women’s Experiences and Perspectives on the Acceptability and Feasibility of Copackaged Medicine for Antenatal Care and PMTCT in Lesotho by Michelle M. Gill, Heather J. Hoffman, Appolinaire Tiam, Florence M. Mohai, Majoalane Mokone, Anthony Isavwa, Sesomo Mohale, Matela Makhohlisa, Victor Ankrah, Chewe Luo, Laura Guay

“…Implementation was also feasible; 85.2% of SI participants reported adequate counseling time, though 37.8% felt pack use caused clinic delays. …”
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High CXCR3 on Leukemic Cells Distinguishes IgHVmut from IgHVunmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones by Gayane Manukyan, Tomas Papajik, Zuzana Mikulkova, Renata Urbanova, Veronika Smotkova Kraiczova, Jakub Savara, Milos Kudelka, Peter Turcsanyi, Eva Kriegova

“…Levels of CXCR3 on CD5low subpopulation were associated with time to the next treatment, thus further confirming its prognostic value. …”
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Association of Cancer and the Risk of Developing Atrial Fibrillation: A Systematic Review and Meta-Analysis by Ming Yuan, Zhiwei Zhang, Gary Tse, Xiaojin Feng, Panagiotis Korantzopoulos, Konstantinos P. Letsas, Bryan P. Yan, William K. K. Wu, Huilai Zhang, Guangping Li, Tong Liu, Yunlong Xia

“…The risk of atrial fibrillation was highest within 90 days of cancer diagnosis (OR 7.62, 95% CI 3.08 to 18.88, p<0.00001) and this risk diminished with time. Conclusions. The risk of AF was highest within 90 days of cancer diagnosis. …”
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