Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose by Yijun Zhou, Chaojun Qi, Shu Li, Xinghua Shao, Zhaohui Ni

“…Western blot and real-time PCR analyses were used to detect PTX3, p-IKBa/IKBa (I-kappa-B-alpha), and p-eNOS/eNOS (endothelial nitric oxide synthase) expression in mice and HUVECs. …”
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Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume-to-Platelet Count Ratio as Biomarkers in Critically Ill and Inj... by Dragan Djordjevic, Goran Rondovic, Maja Surbatovic, Ivan Stanojevic, Ivo Udovicic, Tamara Andjelic, Snjezana Zeba, Snezana Milosavljevic, Nikola Stankovic, Dzihan Abazovic, Jasna Jevdjic, Danilo Vojvodic

“…NLR and MPV were very good independent predictors of lethal outcome. For the first time, we demonstrate that nature of bacteremia influences MPV/PC, MLR, and PLR. …”
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Difference of clinical characteristics in patients with reinfection and primary infection variants of SARS-CoV-2: a retrospective study in China by Chao-Chao Qiu, Xiao-Qing Lin, Qiang Zhang, Ya-Long Chen, Xiao-Qiao Su, Ming-Ying Zhang, Le-Fei Zhu, Zhi-Ruo Lin, Fang Cheng, Shang-Ren Xie, Ji-Chan Shi, Xian-Gao Jiang

“…The observation group exhibited a shorter clinical symptom recovery time than that did the control group (median, 5 days vs. 7 days, Log rank p<0.001, HR = 1.907(95% CI 1.669–2.178). …”
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Uji Daya Hambat Ekstrak Buah Belimbing Manis (Averrhoa carambola) terhadap Pertumbuhan Bakteri Streptococcus pneumoniae secara In Vitro by Rita Risandi, Aziz Djamal, Asterina Asterina

“…No inhibition zones formed on blood agar and there is no effect of contact time extracts of star fruit (carambola Averhhoa) on the growth of the bacterium Streptococcus pneumoniae in vitro. …”
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Clinicopathological and Prognostic Significance of CD47 Expression in Lung Neuroendocrine Tumors by Mario Orozco-Morales, Alejandro Avilés-Salas, Norma Hernández-Pedro, Rodrigo Catalán, Graciela Cruz-Rico, Ana Laura Colín-González, Elsa Dosal-Mancilla, Pedro Barrios-Bernal, Oscar Arrieta

“…In patients with high-grade tumors (this time defined as Ki‐67>40%), the positive expression of CD47 was strongly associated with an increased PFS. …”
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Protective Effects of NaHS/miR-133a-3p on Lipopolysaccharide-Induced Cardiomyocytes Injury by Yi-Mei Jin, Ai-Rong Huang, Mei-qian Yu, Wan-Ding Ye, Xiao-guang Hu, Hua-min Wang, Zhi-wei Xu, Dong-shi Liang

“…The adenosine triphosphate (ATP) kit was used to detect ATP content; real-time quantitative polynucleotide chain reaction (qPCR) was used to measure the levels of mammalian targets of rapamycin (mTOR), AMP-dependent protein kinase (AMPK), and miR-133a-3p, and Western blot (WB) was used to detect protein levels of mTOR, AMPK, myosin-like Bcl2 interacting protein (Beclin-1), microtubule-associated protein 1 light chain 3 (LC3I/II), and P62 (sequestosome-1, sqstm-1/P62). …”
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Effect of auricular acupoint pressing combined with acupoint application in the treatment of senile constipation (耳穴压豆联合穴位贴敷治疗老年性便秘效果观察) by KAN Haiying (坎海英), ZHOU Weihua (周维华)

“…Results Shorter inter-defecatory time interval and defecation duration, and higher scores of defecation sensation and fecal Characteristics were observed in the observation group compared with those in the control group (P＜0. 05). …”
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Enhancing pathogens detection in suspected geriatric bloodstream infections using Nanopore-targeted sequencing by Menghui Zhao, Yan Ouyang, Junchi Mei, Hang Liu

“…NTS exhibited a significantly higher pathogen detection rate and faster turnaround time than blood culture (78.1% vs 42.2%, P < 0.001), with an agreement rate of 65.6%. …”
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Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study by John Wogabaga, Kathy Burgoine, Abel Kakuru, Brendah Nambozo, Martin Chebet, Josephine Tumuhamye, Benon Wanume, Faith Oguttu, Milton W. Musaba, Agnes Napyo, Solomon Wani, Peter Olupot-Olupot, Andrew D. Weeks, Thorkild Tylleskär, David Mukunya

“…Bivariable and multivariable analyses were conducted using Cox proportional hazard regression models to estimate hazard ratios (HR) of selected exposures and time to omphalitis. Results A total of 2052 neonates were enrolled; half of which were female (51.1%). …”
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Subclinical Inflammatory Status in Rett Syndrome by Alessio Cortelazzo, Claudio De Felice, Roberto Guerranti, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Gloria Zollo, Claudia Landi, Giuseppe Valacchi, Lucia Ciccoli, Luca Bini, Joussef Hayek

“…Our findings reveal for the first time the presence of a subclinical chronic inflammatory status related to the “pseudo-autistic” phase of RTT, which is related to the severity carried by the MECP2 gene mutation.…”
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Irisin reshapes bone metabolic homeostasis to delay age-related osteoporosis by regulating the multipotent differentiation of BMSCs via Wnt pathway by Shangman Xing, Yifan Ma, Bing Song, Bing Song, Min Bai, Kexin Wang, Wenjing Song, Tingting Cao, Chao Guo, Yanying Zhang, Zhandong Wang, Yongfeng Wang, Yongfeng Wang

“…Nonetheless, the targeting effect of irisin on age-related osteoporosis and its underlying molecular biological mechanisms remain unclear.MethodsThe specific role of irisin in osteogenic-adipogenic differentiation in young or aging BMSCs was evaluated by multiple cells staining and quantitative real-time PCR (RT-qPCR) analysis. RNA-seq and protein Western blotting excavated and validated the key pathway by which irisin influences the fate determination of aging BMSCs. …”
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Optimising the Design of a Hybrid Fuel Cell/Battery and Waste Heat Recovery System for Retrofitting Ship Power Generation by Onur Yuksel, Eduardo Blanco-Davis, Andrew Spiteri, David Hitchmough, Viknash Shagar, Maria Carmela Di Piazza, Marcello Pucci, Nikolaos Tsoulakos, Milad Armin, Jin Wang

“…It assesses the environmental impact by including upstream emissions integrated with the Energy Efficiency Existing Ship Index (EEXI) and the Carbon Intensity Indicator (CII) calculations. Real-time data have been collected from a Kamsarmax vessel to build a hybrid marine power distribution plant model for simulating six system designs. …”
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Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential by Valentina Sesti, Arianna Magni, Matteo Moschetta, Chiara Florindi, Marlene E. Pfeffer, Mattia Lorenzo DiFrancesco, Michele Guizzardi, Giulia Folpini, Luca Sala, Alessandra Gilda Ritacca, Beatrice Campanelli, Paola Moretti, Giuseppe Maria Paternò, Luca Maragliano, Matteo Tommasini, Francesco Lodola, Elisabetta Colombo, Fabio Benfenati, Chiara Bertarelli, Guglielmo Lanzani

“…The most promising species, MTP2, was extensively studied. Time-resolved spectroscopy techniques provide insights into the excited state evolution and a complete understanding of its isomerization reaction. …”
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Ultrasound-Guided Peripheral Nerve Blocks Performed by Orthopedic Surgeons: A Retrospective, Multicenter Study in Akita Prefecture, Japan by Tatsuru Tomioka, Seietsu Senma, Yuichiro Narita, Masakazu Urayama, Satoshi Yumoto, Hiroki Ito, Toshiaki Aizawa, Tsuyoshi Shirahata, Hiroshi Aonuma, Nozomi Kaga, Norimitsu Masutani, Yusuke Yuasa, Hikaru Saito, Kunio Ebata, Kentaro Ouchi, Naohisa Miyakoshi, Yoichi Shimada

“…The block site and the hospital where the block was performed showed a significant relationship with the addition of local anesthetics to the surgical site (P<0.001). Surgery time, age at surgery, and surgical site showed no significant relationships with the addition of local anesthetics. …”
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The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C by Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin

“…Assessment of polymorphism of the studied genes was carried out by real-time polymerase chain reaction with melting curve analysis. …”
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Pembangunan Aplikasi Virtual Reality Tur Perumahan Pada Balimbingan Permai Regency (PT. Karya Propertindo Utama) by Komang Candra Brata, Reinhard Jonathan Silalahi, Adam Hendra Brata

“…The main feature of the proposed app is to manage and display all types and details of the house unit catalog in Virtual Reality so that it can be used as an alternative solution for prospective buyers who cannot conduct direct site surveys due to limited time and distance issue. The usability testing results on a total of 20 respondents showed that the application for users received a usability value response of 82%, which was included in the excellent category. …”
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Prediction of growth and feed efficiency in mink using machine learning algorithms by A. Shirzadifar, G. Manafiazar, P. Davoudi, D. Do, G. Hu, Y. Miar

“…Measuring individual daily feed intake and BW is time-consuming, labor-intensive, and stressful for the animals and mink producers. …”
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Identification of a postoperative survival scoring index for adult liver transplantation by Shuai Wang, Xiaohong Lin, Yefu Li, Zhonghao Xie, Ming Zhang, Yicheng Liang, Chuchen Zhu, Yuqi Dong, Ping Zeng, Xiaoshun He, Weiqiang Ju, Maogen Chen

“…Finally, the interpretation of the long-term mortality and subgroup analyses extended the application of the POSS index.Results Finally, a total of five factors (donor sex, recipient body mass index (BMI), total bilirubin (Tbil), international normalized ratio (INR) and total operative time) were identified as independent risk parameters and included in our POSS index. …”
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Cause-Effect Relationships between Painful TMD and Postural and Functional Changes in the Musculoskeletal System: A Preliminary Report by Adam Andrzej Garstka, Monika Brzózka, Aleksandra Bitenc-Jasiejko, Roman Ardan, Helena Gronwald, Piotr Skomro, Danuta Lietz-Kijak

“…On the other hand, the displacement of the articular disc was diagnosed on the basis of the diagnostic criteria of temporomandibular disorders (RDC/TMD IIa)—displacement of the articular disc without reduction. At the same time, the body posture was assessed by inspection and using computer techniques while standing and during motion. …”
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Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD by Pritha Majumder, Biswanath Chatterjee, Khadiza Akter, Asmar Ahsan, Su Jie Tan, Chi-Chen Huang, Jen-Fei Chu, Che-Kun James Shen

“…Conclusions This study, for the first time, highlights the importance of posttranslational modification of RBPs, such as the neurodevelopmental disease-related protein FMRP, as the molecular switch regulating the dendrite-to-spine transport of specific mRNAs under mGluR1-mediated neurotransmissions. …”
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