Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff by Jing Zhang, Zhengzheng Wu, Liangnan Sun, Xin-hua Liu

“…All participants completed Ocular Surface Disease Index (OSDI) and Standard Patient Dry Eye Evaluation (SPEED) questionnaires for dry eye severity, as well as Schirmer I and tear break-up time (TBUT) tests. LipiView® II Ocular Surface Interferometer was used for lipid layer thickness (LLT), MG dropout, and partial blink (PB) rate tests. …”
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Analysis of Circulating MicroRNAs In Vivo following Administration of Dexamethasone and Adrenocorticotropin by Ivan Igaz, Gábor Nyírő, Zoltán Nagy, Henriett Butz, Zsolt Nagy, Pál Perge, Peter Sahin, Miklós Tóth, Károly Rácz, Peter Igaz, Attila Patócs

“…Total RNA was isolated and microRNA expression was analyzed by real-time reverse transcription quantitative polymerase chain reaction normalized to cel-miR-39 as reference. …”
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大麻素1型受体在实验性自身免疫性脑脊髓炎小鼠中的 动态表达及其作用

“…EAE 和特异性CB1R抑制剂(SR141716A,SR1)干预组小鼠的神经功能缺损症状和体质量变化;用real time PCR检测CB1R mRNA表达;Western blot和荧光免疫组织化学法检测CB1R蛋白表达;用ELISA法检测细胞因子IL-1β?…”
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Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques by Nico A Flierman, Sue Ann Koay, Willem S van Hoogstraten, Tom JH Ruigrok, Pieter Roelfsema, Aleksandra Badura, Chris I De Zeeuw

“…We found that single-unit DN neurons modulated spiking activity over the entire time course of the task, and that their activity often bridged temporally separated intra-trial events, yet in a heterogeneous manner. …”
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Age but not vitamin D is related to sarcopenia in vitamin D sufficient male elderly in rural China by Weinuo Mi, Huifeng Zhang, Lina Zhang, Xingjia Li, Zhiguo Wang, Yu Sun, Tonggao Shen, Kuanlu Fan, Chao Liu, Shuhang Xu

“…Correlation analyses of sarcopenia components revealed that age was negatively correlated with SMI and gait speed in male elderly, but negatively correlated with the gait speed and positively correlated with the time to complete 5 sit-to-stand movements in female elderly. …”
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Enhancing Bioactive Cordycepin Production via Precision Fermentation with an Engineered <i>Aspergillus oryzae</i> by Jutamas Anantayanon, Warinthon Chamkhuy, Nakul Rattanaphan, Sarocha Panchanawaporn, Kobkul Laoteng, Sukanya Jeennor

“…As predicted, the maximum cordycepin concentration (1724.53 ± 18.30 mg/L) was obtained with a short fermentation time (2 days). A significant increase in cordycepin yield (>50% increase) was observed in the culture grown in the optimized culture medium compared to that grown in the basal medium. …”
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The application of emerging technologies for the quality and safety evaluation of oilseeds and edible oils by Xue Li, Wenwen Liu, Lu Xiao, Jie Zhao, Yan Chen, Liangxiao Zhang, Peiwu Li, Dolores Pérez-Marín, Xu Wang

“…Classical techniques widely used to detect the safety and quality attributes of oilseeds and edible oils often involve time-consuming and tedious operation; therefore, the development of low cost, rapid and non-destructive detection method is necessary. …”
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Evaluation of Digital PCR as a Technique for Monitoring Acute Rejection in Kidney Transplantation by Hyeseon Lee, Young-Mi Park, Yu-Mee We, Duck Jong Han, Jung-Woo Seo, Haena Moon, Yu-Ho Lee, Yang-Gyun Kim, Ju-Young Moon, Sang-Ho Lee, Jong-Keuk Lee

“…Plasma and/or urine samples were isolated from 34 kidney recipients at multiple time points after transplantation, and analyzed by dPCR using the QX200. …”
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Impact of a new case-based payment scheme on volume distribution across public hospitals in Zhejiang, China: does ‘Same disease, same price’ matter by Meiteng Yu, Jing Liu, Tao Zhang

“…A total of 3848 observation points were examined using two sets of controlled interrupted time series analyses to assess the effects of this new case-based payment, without and with “same disease, same price”, on the proportion of discharges, total medical revenue and hospitalization revenue. …”
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Novel application of an imageless robotic system in simultaneous unicompartmental knee arthroplasty and anterior cruciate ligament reconstruction by Joshua Yeuk Shun Tran, Rex Wang-Fung Mak, Kevin Ki-Wai Ho, Jonathan Patrick Ng, Cham Kit Wong, Gloria Yan-Ting Lam, Tsz Lung Choi, Michael Tim-Yun Ong, Patrick Shu-Hang Yung

“…The robotic system facilitates real-time gap assessment and balancing, reducing the risk of over- or under-constraint during ACL graft tensioning.The procedure was performed with a standard medial parapatellar approach. …”
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Network pharmacology-based screening of the active ingredients and mechanisms of Cymbaria daurica against diabetes mellitus by Ruyu Shi, Dongxue Chen, Mingyue Ji, Baochang Zhou, Ziyan Zhang, Chunhong Zhang, Minhui Li

“…Then, a HepG2 cell insulin resistance model and a high-fat, high-glucose diet combined with a streptozotocin-induced T2DM rat model was established to assess the fasting glucose changes and lipid profile after C. daurica treatment, respectively. Finally, real-time PCR and western blotting were used to verify changes in key targets. …”
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Long-term drought and risk of infant mortality in Africa: A cross-sectional study. by Pin Wang, Tormod Rogne, Joshua L Warren, Ernest O Asare, Robert A Akum, N'datchoh E Toure, Joseph S Ross, Kai Chen

“…The association between drought exposure and infant mortality risk was estimated using Cox regression models allowing time-dependent covariates. We further examined whether the association varied for neonatal and post-neonatal mortality and whether there was a delayed association with drought exposure during pregnancy or infancy. …”
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HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells by Yoo-Wook Kwon, Hyo-Suk Ahn, Jin-Woo Lee, Han-Mo Yang, Hyun-Jai Cho, Seok Joong Kim, Shin-Hyae Lee, Heung-Mo Yang, Hyun-Duk Jang, Sung Joo Kim, Hyo-Soo Kim

“…Although human induced pluripotent stem cells (iPSCs) can serve as a universal cell source for regenerative medicine, the use of iPSCs in clinical applications is limited by prohibitive costs and prolonged generation time. Moreover, allogeneic iPSC transplantation requires preclusion of mismatches between the donor and recipient human leukocyte antigen (HLA). …”
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Home-based strength and balance exercises for fall prevention among older individuals of advanced age: a randomized controlled single-blind study by Jian Zhou, Bo Liu, Jian-fang Xu, Fu-bai-hui Wang, Hui Ye, Jin-Ping Duan, Xin-wen Cui

“…Adherence was better in the test group, with 54.0% exercised ≥ 3 times per week and 28.6% exercised 1–2 times per week on average.Conclusion Home-based strength and balance exercises improved balance and reduced the risk of falls among the individuals of advanced age. …”
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BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

“…Administered at birth, BCG induces broad immune responses against a large number of antigens shared with Mycobacterium tuberculosis (Mtb), but protection wanes over time. We have previously shown that unconventional B cell subsets play a role in tuberculosis control.MethodsHigh-dimensional flow cytometry and multiplex cytokine analysis were employed to investigate the effects of immunotherapy on BCG-vaccinated mice in an Mtb challenge model.ResultsIn this study, we investigate the potential of recombinant cytokines targeting B cells – B-cell activating factor (BAFF) and A proliferation-inducing ligand (APRIL) – to modulate BCG immunity and improve protection in mice. …”
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Compact Quantum Cascade Laser-Based Noninvasive Glucose Sensor Upgraded with Direct Comb Data-Mining by Liying Song, Zhiqiang Han, Hengyong Nie, Woon-Ming Lau

“…Specifically, the sensor performance is validated with 492 glucose absorption scans in the time domain, each with 20 million datapoints measured from four subjects with glucose concentrations of 3.9–7.9 mM. …”
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Experimental study on the effect of ion transmission mode on the calcium leaching rate of cementitious materials by Shihao An, Chunmeng Jiang, Shuangxi Li, Chong Shi

“…In addition, XRD, MIP, and SEM assessments were used to observe and analyze the changes in the phase composition, pore structure, and microscopic morphology of the various types of specimens before and after calcium leaching. The time-varying behavior and damage mechanisms of the specimens of cementitious material systems with different aggregate compositions under the action of calcium leaching were investigated using macroscopic indexes with microscopic tests. …”
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Long-term maintenance of patient-specific characteristics in tumoroids from six cancer indications by Colin D. Paul, Chris Yankaskas, Pradip Shahi Thakuri, Brittany Balhouse, Shyanne Salen, Amber Bullock, Sylvia Beam, Anthony Chatman, Sybelle Djikeng, Xiaoyu Jenny Yang, Garrett Wong, Isha Dey, Spencer Holmes, Abigail Dockey, Lindsay Bailey-Steinitz, Lina Zheng, Weizhong Li, Vivek Chandra, Jakhan Nguyen, Jason Sharp, Erik Willems, Mark Kennedy, Matthew R. Dallas, David Kuninger

“…An example application of these models for assessing the cytotoxicity of a natural killer cell line and primary natural killer cells over time and at various doses demonstrated the compatibility of these models with assays used in compound and cell therapy development. …”
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Klasifikasi Intensi dengan Metode Ling Short-Term Memory pada Chatbot Bahasa Indonesia by Faiz Aulia Al Farisi, Rizal Setya Perdana, Putra Pandu Adikara

“…Therefore, the solution offered is the implementation of a chatbot, so that it can serve at any time, while easing the work of staff. This study attempts to design one of the components of the chatbot, namely the intention classification model, using the Long Short-Term Memory method. …”
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Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization by Caden G. Bonzerato, Katherine R. Keller, Richard J. H. Wojcikiewicz

“…Conclusions For the first time, Bok was shown to directly suppress IP3R1 activity, which was reversed by Ser-8 phosphorylation. …”
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