Adverse drug events (ADEs) risk signal mining related to eculizumab based on the FARES database by Xi-Feng Wang, Lu-Ri Bao, Ta-La Hu, Rui-Feng Xu, Wu-Niri Gao, Jing-Yuan Wang, Jian-Rong Zhao, Zhen-Li Fu, Shu-Fang Wang, Yan Meng

“…Some PTs, such as aplastic anemia, gene mutation, mastication disorder, kidney fibrosis, BK virus infection, abnormal neutrophil count, C3 glomerulopathy, neuroblastoma, and glomerulonephritis membranoproliferative, were also detected outside the instructions. The median time to onset of eculizumab adverse events was 159 days (interquartile range [IQR] 11∼738 days). …”
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Carnitine palmitoyltransferase 1C promotes EMT-associated cisplatin resistance in non-small cell lung cancer cells by Renjie Chen, Jiahui Wang, Shuoyu Huang, Xuefeng Hu, Xinran He, Tiange Zhang, Yunhan Hu, Huijun Wei, Sihui Nian, Yushu Huang, Zhihao Wu

“…Conclusions: These data provide evidence for the first time that the lipid metabolism enzyme, CPT1C, mediates resistance to chemotherapy. …”
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La atención de las necesidades educativas especiales y la labor docente en la escuela primaria / Response to Special Educational Needs and Teaching Efforts in Elementary School by Mayela Dabdub-Moreira, Alejandra Pineda-Cordero

“…The main limitations facing teachers are lack of time and poor parental support. The areas in which teachers indicated they need training were related to curricular modifications and specific methodologies for SEN. …”
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Alkali Effect on Alkali-Surfactant-Polymer (ASP) Flooding Enhanced Oil Recovery Performance: Two Large-Scale Field Tests’ Evidence by Chen Sun, Hu Guo, Yiqiang Li, Guipu Jiang, Ruicheng Ma

“…How to choose alkali in ASP flooding remains a question for a long time. As the world’s only and largest ASP flooding application place, Daqing Oilfield has always adhered to the strategy of parallel development of strong alkali ASP flooding (SASP) and weak alkali ASP flooding (WASP), but SASP is in a dominant position, indicated by more investments and more project numbers. …”
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Impact of eggshell membrane on metabolism and cell adhesion in oxidatively stressed canine chondrocytes by Juraj Vozar, Nikola Hudakova, Natalia Nosalova, Mykhailo Huniadi, Dana Marcincakova, Slavomir Hornak, Lubica Hornakova, Petra Majerova, Dasa Cizkova, Dasa Cizkova

“…This significant therapeutic potential was validated through XTT assays, which measured cell metabolic activity at 24 h, and Real-time Cell Analysis (RTCA), providing continuous monitoring over 98 h. …”
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Pathways to care for psychosis in rural Uganda: Mixed-methods study of individuals with psychosis, family members, and local leaders by Yang Jae Lee, Kayera Sumaya Nakaziba, Sophie Waimon, Grace Agwang, Kailash Menon, Sam Samuel, Aaron Damon Dyas, Travor Nkolo, Haba Ingabire, Jason Wykoff, Olivia Hobbs, Rauben Kazungu, Job Basiimwa, Robert Rosenheck, Scholastic Ashaba, Alexander C. Tsai

“…While 81% of participants eventually accessed biomedical care, the median time to first biomedical contact was 52 days, compared to 7 days for any care modality. …”
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Treatment and Outcomes of Pancreatic Cancer in Armenia: A Retrospective Study From Resource-Limited Settings by Elen Baloyan, Davit Zohrabyan, Liana Safaryan, Armen Avagyan, Lilit Harutyunyan, Vardan Bardakhchyan, Jemma Arakelyan, Amalya Sargsyan, Martin Harutyunyan, Mariam Mailyan, Gevorg Tamamyan, Samvel Bardakhchyan

“…The median age at diagnosis was 63 years. The median follow-up time was 11 months (range, 2-146). A total of 11.4% of patients had stage I-II, 27.1% had stage III, and 60% had stage IV disease. …”
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Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters by I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, I. A. Drachkova, E. A. Oshchepkova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, V. A. Kozlov

“…Immunopathogenesis is based on the mechanisms of the breakdown of immune tolerance to its own antigens, which is characterized by an increase in the activity of T-effector cells, causing RA symptomatology. At the same time, against the background of such increased activity of effector lymphocytes, a decrease in the activity of a number of regulatory cells, including regulatory T-cells (Treg) and myeloid suppressor cells, is recorded. …”
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Nanoliposomal L-Asparaginase and Its Antitumor Activities in Lewis Lung Carcinoma Tumor-Induced BALB/c Mice by Thi Thao Do, Thi Phuong Do, Thi Nga Nguyen, Thi Cuc Nguyen, Thi Thu Phuong Vu, Thi Giang An Nguyen

“…However, the antitumor activity of liposomal L-ASP was significantly greater than that of untrapped L-ASP at the same doses (6 UI/mouse) in terms of tumor size (6309.11 ± 414.06 mm3) and life span (35.00 ± 1.12 days). This is the first time the antitumor activities of PEGylated nanoliposomal L-ASP have been assessed in LLC carcinoma tumor-induced BALB/c mice and showed significantly improved pharmacological properties compared to those of free L-ASP (P<0.05). …”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles for Regenerative Applications and Radiotherapy by Ning Wang, Feifei Ma, Huijuan Song, Ningning He, Huanteng Zhang, Jianguo Li, Qiang Liu, Chang Xu

“…Although many clinical treatments are currently available for tissue repair, they are expensive. The long recovery time and some unavoidable complications such as cell damage and the inflammatory reaction caused by radiotherapy have led to unsatisfactory results. …”
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Reagent-free Hyperspectral Diagnosis of SARS-CoV-2 Infection in Saliva Samples by Brandon Saint-John, Alejandro Wolf-Yadlin, Daniel E. Jacobsen, Jamie L. Inman, Serge Gart, Matt Keener, Cynthia McMurray, Antoine M. Snijders, Harshini Mukundan, Jessica Z. Kubicek-Sutherland, James B. Brown

“…Furthermore, we developed state-of-the-art ML pipelines for near real-time analysis of spectral signatures in saliva samples. …”
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Multidimension Analysis of the Prognostic Value, Immune Regulatory Function, and ceRNA Network of LY6E in Individuals with Colorectal Cancer by Ting Li, Weidong Liu, Chun Wang, Man Wang, Wenjia Hui, Jiajie Lu, Feng Gao

“…A ceRNA expression-based nomogram was established. Real-time PCR (qRT-PCR) was applied to validate the expression of LY6E-related ceRNA in CRC cell lines. …”
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Comparative Efficacy of Esketamine vs Sufentanil with Propofol for Sedation in EUS: A Randomized, Controlled Study by Liu C, Wang Y, Yin Y, Wang P, Ji X, Sun J, Zhao S, Jia Y, Liu S, Zhou Z

“…Compared to the sufentanil group, the induction time of sedation in the esketamine group was shorter, and the hemodynamics were more stable (P < 0.05). …”
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Newborn morbidities and care procedures at the special newborn care units of Gandaki Province, Nepal: a retrospective study by Khim Bahadur Khadka, Nabina Koirala, Olena Ivanova, Ramchandra Bastola, Dela Singh, Kamala Rana Magar, Bidhya Banstola, Ramesh Prasad Adhikari, Vincentas Giedraitis, Deepak Paudel, Guenter Froeschl

“…Female newborns had a 0.45-times (CI: 0.23–0.84) lower risk of mortality compared to male newborns. …”
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INDUSTRIAL POLICY IN ASIAN NEWLY INDUSTRIALIZED COUNTRIES: CONTROVERSIES, REVIEW AND LESSONS by Dejana Gajinov

“…The key conclusion is that there is room for successful industrial policy even in countries that have reached the technological frontier and want to push it further, as well as in countries lagging behind in industrial development, although the global context in which industrial policy is situated has changed over time. A special commentary is referred to the economic and industrial development of the former countries of Yugoslavia. …”
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Neuroprotective Potential of <i>Origanum majorana</i> L. Essential Oil Against Scopolamine-Induced Memory Deficits and Oxidative Stress in a Zebrafish Model by Ion Brinza, Razvan Stefan Boiangiu, Iasmina Honceriu, Ahmed M. Abd-Alkhalek, Samir M. Osman, Omayma A. Eldahshan, Elena Todirascu-Ciornea, Gabriela Dumitru, Lucian Hritcu

“…OmEO can enhance memory through AChE inhibition, reduce SCOP-induced anxiety by increasing the time spent in the top zone in the NTT, and significantly reduce oxidative stress markers. …”
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The clinical frailty scale is associated with an increased risk of postoperative complications and the development of post-traumatic osteoarthritis in elderly patients with trimall... by Qingsong Zhou, Wei Deng, Ming Zhao, Wei Zhou, Duo Chen, Heng Wang, Shengtao Wang, Hongsheng Yang, Yong Yin

“…Method All patients aged 65 and older underwent open reduction and internal fixation for trimalleolar fractures between January 2015 to January 2023 were selected. Follow-up time was at least 1 year. Patients with post-traumatic osteoarthritis, bone tumors, bone infection, and other diseases before surgery were excluded. …”
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ŽINOJIMO SOCIALUMO PROBLEMA ŠIUOLAIKINĖJE SOCIALINĖJE EPISTEMOLOGIJOJE: DU POŽIŪRIAI by Audronė Rimkutė

“…Additionally, sociologistic concept of knowledge is not very suitable for knowledge economics, because it narrows its work to already institutionalised knowledge and says nothing about new knowledge. At the same time, sociologistic concept of knowledge is redundant for science policy, because some of Fuller’s proposals for science democratisation would be better grounded, if they invoked the realistic concept of science. …”
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Deciphering salt-responsive NB-ARC genes in rice transcriptomic data: A bioinformatics approach with gene expression validation by Saputro Triono Bagus, Wardhani Fila Oxi, Sholihah Nur Fadlilatus, Ermavitalini Dini, Purnama Putut Rakhmad, Nurhidayati Tutik

“…Two varieties with contrasting tolerance levels were selected for validation. Real-time polymerase chain reaction was employed to determine the gene expression for validation. …”
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SS316/CCA laminated metal composite fabricated by additive friction stir deposition: Microstructure and mechanical properties by Ravi Sankar Haridas, Anurag Gumaste, Eric Kusterer, Devin Davis, Supreeth Gaddam, Brandon McWilliams, Kyu C. Cho, Rajiv S. Mishra

“…Conventionally, adhesive bonding, roll bonding or deposition methods are used to engineer the LMC for property optimization. For the first time, the present study investigated the potential of the novel solid-state additive friction stir deposition (AFSD) technique to additively manufacture an LMC containing SS316 and Fe40Co20Mn20Cr15Si5 complex concentrated alloy (CS-CCA) exhibiting transformation induced plasticity (TRIP). …”
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