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50541
Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1
Published 2025-01-01“…FLIPR Calcium 6 dye concentration, loading time, and TRPM8 transfected cell seeding density were optimized and a DMSO tolerance of ≤0.2 % was set. …”
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50542
Uji Daya Hambat Air Perasan Buah Jeruk Nipis (Citrus aurantifolia s.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Secara In Vitro
Published 2013-01-01“…<br />The results showed that the lime fruit (Citrus aurantifolia S.) squeeze has the ability to inhibite the bacterial growth of Staphylococcus aureus with various concentrations of 25%, 50%, 75%, and 100% and there is the effect of contact time on the growth of bacteria which the bacteria do not grow after contact the first 5 minutes and the next minute followed by lime fruit squeeze with 100% concentration lime fruit squeeze. …”
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50543
Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B
Published 2025-02-01“…Results A total of 1942 CHB patients were included (10–90% follow-up time 3–60 months), and 104 patients with elevated AFP (5.3%) and 27 patients with HCC development (1.4%) were identified during the follow-up. …”
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50544
Restoring tendon microenvironment in tendinopathy: Macrophage modulation and tendon regeneration with injectable tendon hydrogel and tendon-derived stem cells exosomes
Published 2025-05-01“…Notably, it was discovered for the first time that the tdECM hydrogel promotes M2 macrophage polarization, thereby exerting an anti-inflammatory effect in vivo. …”
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50545
The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns
Published 2018-01-01“…In the vestibular sensory organ, however, the Pax2 expression is localized in hair cells at postnatal day 7, while Sox2 is still expressed in both the hair cells and supporting cells at that time. Prox1 was transiently expressed in the presumptive hair cells and developing supporting cells, and lower Prox1 expression was observed in the vestibular sensory organ compared to the organ of Corti. …”
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50546
Acute effect of a Mediterranean-style dietary pattern (MDP) on mood, anxiety and cognition in UK adults with mild to moderate anxiety and depression: the MediMood randomised contro...
Published 2024-12-01“…A linear mixed model and/or paired analysis will be used to compare the effects of treatments over time.Ethics and dissemination The study has received a favourable ethics opinion from the National Health Service London Queen Square Research Ethics Committee (22/LO/0796). …”
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50547
Attendance of Patients with ophthalmological problems about Eye Protection from UV/blue Light Radiation from Sun light and Electronic Devices in Sulaimani City
Published 2018-07-01“…Ultraviolet (UV) and blue light are affecting eyes during the daily time and may cause many eye’s problems and diseases. …”
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50548
Community disaster exposure and first onset of depression: A panel analysis of nationally representative South African data, 2008-2017.
Published 2022-04-01“…Risk of first depression onset between individuals exposed and unexposed to community disaster was measured, accounting for multiple disaster exposure over time by fitting generalized estimating equation (GEE) regression models. …”
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50549
Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau p...
Published 2024-07-01“…Administration of AAV-Tau[R406W] resulted in increased expression of the Htr7, Htr1a, and Cdk5 genes in the prefrontal cortex compared to AAV-EGFP animals. At the same time, amisulpride at the dose of 10 mg/kg in animals from the AAV-Tau[R406W] group caused a decrease in the Htr7, Htr1a genes mRNA levels compared to animals from the AAV-Tau[R406W] group treated with saline. …”
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50550
Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores
Published 2025-01-01“…We saw no significant association between the T1D or T2D PRS and BMI at diagnosis, time to insulin, or the presence of T1D or T2D diagnostic codes amongst the T2D or ambiguous cases, suggesting that these clinical features are not particularly helpful for aiding diagnosis in ambiguous cases. …”
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50551
Development of a Multi-Sensor Mobile Device for Urban Air Quality Monitoring at the Street Corner: The SMILE Project
Published 2025-01-01“…., government-operated fixed stations) located within an 8 km radius of the center of Marseille. Real-time data is made available through a dedicated software server platform, offering geo-localized air quality information and detailed reports. …”
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50552
Cultures for acid-fast bacilli: are we being good stewards?
Published 2025-01-01“…The number of specimens processed by the microbiology laboratory required 2 full-time microbiology technicians to process specimens. …”
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50553
Antimicrobial Susceptibility of <i>Glaesserella parasuis</i> to Macrolides and Characterization of <i>erm</i>(T)-Carrying Mobile Elements on Chromosome
Published 2025-01-01“…To the best of our knowledge, integrative and conjugative element (ICE)-borne <i>erm</i>(T) in <i>G. parasuis</i> is reported for the first time in this study. Taken together, these results provide insights into the susceptibility of <i>G. parasuis</i> to macrolides. …”
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50554
Detection and subtyping of Blastocystis sp. in human and animal stool samples using high-resolution melting analysis
Published 2025-02-01“…HRM analysis was then employed to identify and differentiate Blastocystis subtypes using specific primers via real-time PCR. Results Six subtypes were identified, with ST7 (30%) being the most prevalent, followed by ST3 (28%), ST2 (16%), ST1 (14%), ST5 (6%), and ST14 (6%). …”
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50555
Combined oven/freeze drying as a cost and energy-efficient drying method for preserving quality attributes and volatile compounds of carrot slices
Published 2025-01-01“…Drying conditions included 36 hours of FD, OD, and combinations of OD and FD at 1 h of OD + 21 h of FD (OD1-FD21), 2 h of OD + 18 h of FD (OD2-FD18), 3 h of OD + 15 h of FD (OD3-FD15), and 9 h of OD.Results and discussionCompared to FD alone, the OD-FD combination reduced drying time by 39–50% and decreased energy consumption and costs by 40–56%. …”
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50556
Effect of spherical Mo metal particles on microstructure and properties of 316L stainless steel during laser powder bed fusion
Published 2025-01-01“…It was found that the addition of Mo particles significantly affected the solidification behavior and organization of the matrix and formed a unique spherical metal reinforcement in the matrix, which significantly enhanced the strength of the material while avoiding a serious loss of plasticity: compared with PBF-316L, the ultimate tensile strength (UTS) and elongation of 2Mo/316L with 2 wt% Mo particles added were simultaneously increased by 9.7% and 10.4%, which is a good result of improving strength and plasticity at the same time. With the addition of 6 wt% Mo particles, the UTS of 6Mo/316L reaches 952 MPa while still maintaining a good elongation of 21%. …”
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50557
An Environmentally Adaptive CRO-SL Algorithm Based on Dynamic Agents for the Channel Assignment Problem in Wireless Networks
Published 2025-01-01“…The results show that incorporating the new environmental agents into the EnvAdapt-CRO-SL workflow significantly boosts throughput while reducing the computational time required to obtain optimal solutions.…”
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50558
Assessment of the influence of gap wall mobility factor at calculation of leakage in working section of a scroll compressor. Part 2
Published 2023-12-01“…Accordingly, an adequate and qualitative mathematical model should include the factor of non-stationarity of the leakage process, taking into account the mobility of scroll elements. At the same time, the real properties of the working medium, characterized by the compressibility coefficient, play an important role in the nature of leakage. …”
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50559
بررسی اثرات مواجهه با PFOA در دوران بارداری بر بیان فاکتورهای نوروتروفین 3 (NT3) و نوروتروفین 4 (NT4) در مغز نوزادان تازه متولد شدهی موش صحرایی...
Published 2024-08-01“…در گروهای دریافتکنندهی PFOA، این ترکیب بصورت روزانه گاواژ گردید. 20 روز بعد از زایمان، با استفاده از روشهای ELISA و Real Time PCR، بیان فاکتورهای 3NT و 4NT در مغز موشهای نوزاد مورد بررسی قرار گرفت. …”
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50560
Assessment of Treatment Outcomes and Associated Factors Among Pediatric Patients With Burkitt Lymphoma at Kenyatta National Hospital
Published 2025-01-01“…Kaplan–Meier survival and Cox regression analyses were employed to determine the survival time and predictors of mortality, respectively. The median age of the patients at diagnosis was 6 years (range: 3–13 years). …”
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