Revolutionizing Civil Servant’s Work Behavior through Flexible Working Spaces: Digital Transformation &Green Practices at the Ministry of Finance by Puput Yanita Senja, Wahyu Dian Silviani, Rosana Eri Puspita

“…The pandemic also brought other advantages, including carbon emissions reductions and time savings. Conclusion: The FWS concept in the Ministry of Finance changed the work behavior related to the digital transformation, and the green work behavior of the civil servants. …”
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Static and dynamic brain functional connectivity patterns in patients with unilateral moderate-to-severe asymptomatic carotid stenosis by Junjun Wang, Junjun Wang, Linfeng Song, Binlin Tian, Li Yang, Xiaoyu Gu, Xu Chen, Lei Gao, Lin Jiang

“…Dynamic independent component analysis (dICA) was employed to extract independent circuits/networks and to detect time-frequency modulation at the circuit level. Further imaging-behavior associations identified static and dynamic functional connectivity patterns that reflect cognitive decline.ResultsACS patients showed altered functional connectivity in multiple brain regions and networks compared to controls. …”
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Adherence to prehospital thoracostomy practice guidelines for traumatic cardiac arrest: A retrospective study by Nicolas Beysard, Tara Agudo, Peter Serfozo, Tobias Zingg, Perrine Truong, Roland Albrecht, Vincent Darioli, Mathieu Pasquier

“…We sought to analyse the prehospital management and clinical course of patients with TCA, focusing on changes over time in the use of thoracostomy. Methods: In this single-centre retrospective observational study, we included patients with TCA managed by physicians of the prehospital service of Lausanne University Hospital from 2012 to 2024. …”
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Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway by Lingchao Miao, Meng Sam Cheong, Haolin Zhang, Haroon Khan, Haroon Khan, Hongxun Tao, Yuxiao Wang, Wai San Cheang

“…Pro-inflammatory cytokines were determined using ELISA kits, whereas the components of purslane extract were detected by ultra performance liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry. Chronic oral administration of purslane extract ameliorated colon shortening syndrome and reduced bowel inflammation in HFD-induced obese mice through suppression of the toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling pathway to downregulate TLR4, myeloid differentiation factor 88 (MyD88), Ser32 phosphorylation of NF-κB inhibitor alpha (IκBα), and Ser536 phosphorylation of NF-κB p65 expression levels, thereby inhibiting the pro-inflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-6 levels.ConclusionThe present study supports the anti-inflammatory potential of purslane extract for modulating bowel inflammation under obesity through inhibition of the TLR4/NF-κB signaling pathway.…”
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Characterization of a chemically induced osteoarthritis model in zebrafish by Gongyi Xiao, Jin Qin, Huiping Yang, Qizhi Song, Ruobin Zhang, Junlan Huang, Yuexi Mou, Wen Liu, Xianding Sun, Mao Nie

“…Subsequent analyses included histological staining, immunohistochemistry, OA research society international (OARSI) scoring, and real-time in vivo imaging were performed at 7, 14, and 28 days post injection. …”
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Real-world effectiveness of hemodialysis modalities: a retrospective cohort study by Yan Zhang, Anke Winter, Belén Alejos Ferreras, Paola Carioni, Otto Arkossy, Michael Anger, Robert Kossmann, Len A. Usvyat, Stefano Stuard, Franklin W. Maddux

“…Cox regression models with KRT modality and coronavirus disease 2019 (COVID-19) status as time-varying covariates, and adjusted for multiple confounders, were used to estimate all-cause (primary) and cardiovascular (secondary) mortality. …”
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The clinical impact of recent amphetamine exposure in aneurysmal subarachnoid hemorrhage patients by Jeffrey R. Vitt, Roger C. Cheng, Jason Chung, Travis Caton, Bo Zhou, Nerissa Ko, Karl Meisel, Edilberto Amorim

“…There was no difference in the severity of vasospasm or time to peak severity based on recent amphetamine use. …”
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Impact of Age on Short- and Long-Term Outcomes after Pancreatoduodenectomy for Periampullary Neoplasms by Mario Gruppo, Francesca Tolin, Boris Franzato, Pierluigi Pilati, Ylenia Camilla Spolverato, Francesca Zingales, Imerio Angriman, Romeo Bardini

“…No significance was shown for diabetes, radicality of resection, stage of disease, operative time, length of stay, postoperative complications according to the Clavien-Dindo Score, postoperative mortality, pancreatic fistula, and reoperation rates. 69.9% of the patients in group I underwent adjuvant treatment vs. 39.4% of the older ones (p=0.012). …”
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Primary epidemiological evaluation of the effectiveness of the All-National Dispensarization as a cancer screening by the data of the Arkhangelsk Regional Cancer Registry by L. E. Valkova, M. L. Levit, V. M. Merabishvili, A. Yu. Pankrateva, D. M. Dubovichenko, A. V. Agaeva, A. Yu. Ryzhov, E. F. Potekhina, M. Yu. Valkov

“…Anonymous data were taken from the AOCR database about all cases of each of the index MNs (colon, rectum, lung, mammary gland, cervix, uterus, ovary, prostate, and kidney) from 2000 to 2018. The change over time of the number of new cases, crude, age-standardized incidence and the proportion of Stage I, were estimated. …”
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Phasor-FSTM: a new paradigm for multicolor super-resolution imaging of living cells based on fluorescence modulation and lifetime multiplexing by Luwei Wang, Yue Chen, Jiaqing Guo, Xiaoyu Weng, Wei Yan, Jun Song, Tong Ye, Junle Qu

“…We propose a novel multicolor super-resolution imaging method called phasor-based fluorescence spatiotemporal modulation (Phasor-FSTM). This method uses time-resolved detection to acquire spatiotemporal data from encoded photons, employs phasor analysis to simultaneously separate multiple components, and applies fluorescence modulation to create super-resolution images. …”
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Intermittent Fasting: Weighing the Benefits and Drawbacks for Health and Longevity – A Comprehensive Literature Review by Marta Wojtczak, Michał Pniak, Paweł Miklis, Maciej Mawlichanów, Aleksandra Ciesielska, Aleksandra Sieradzka, Krzysztof Szerej, Alicja Kot, Natalia Myśliwiec, Adrian Różycki

“…It compares IF protocols such as alternate-day fasting (ADF), the 5:2 diet, and time-restricted eating (TRE), emphasizing physiological effects and practical implications. …”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…Assessment of patients with erosive form of GERD at endoscopic control during treatment revealed, that epithelialisation of esophageal erosions in medium age group took significantly longer time, than at young patients. GERD develops on a background of significant atrophic and inflammatory changes of gastric mucosa. …”
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Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition by Zsolt Tamás Papp, Polett Ribiczey, Erzsébet Kató, Zsuzsanna E. Tóth, Zoltán V. Varga, Zoltán Giricz, Adrienn Hanuska, Mahmoud Al-Khrasani, Ákos Zsembery, Tibor Zelles, Laszlo G. Harsing, László Köles

“…Our recently published findings indicate that AT₁ receptor activation enhances NMDAR activity in layer V pyramidal neurons of the rat PFC. At the same time, it suggests that alternative angiotensin pathways, presumably involving AT₄ receptors (AT4Rs), might exert inhibitory effects. …”
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Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma by Melody J. Xu, Tara J. Wu, Annemieke van Zante, Ivan H. El-Sayed, Alain P. Algazi, William R. Ryan, Patrick K. Ha, Sue S. Yom

“…Kaplan-Meier method, log-rank tests, and Cox proportional hazards were used for time-to-event analysis. Results Among 20 LRR and 16 DM patients, the median times to recurrence were 51 and 50 months, respectively. …”
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Wnt4、Wnt7a在不同程度脊髓损伤小鼠中的差异表达 by 高敏

“…【方法】采用LISA脊髓撞击器构建小鼠脊髓损伤模型，实验分为SCI0.65组（损伤深度为0.65mm）、SCI0.45组（损伤深度为0.45mm）和Sham组（假手术）；通过BMS评分和CatWalk9.0步态分析系统测试小鼠术后运动功能；应用VonFrey纤毛和冷热板检测小鼠术后神经病理性疼痛；利用Real-time PCR法检测小鼠脊髓损伤节段和腰4腰5（L4-5）节段非经典Wnt信号通路相关基因和PCP相关基因的表达变化。…”
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Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade by Junjie Li, Yuandong Luo, Quanlan Fu, Shuxian Tang, Pingping Zhang, Ian H. Frazer, Xiaosong Liu, Tianfang Wang, Guoying Ni

“…Furthermore, F1/F3 intratumor injection, CD47 blockade, and therapeutic vaccination significantly increases the survival time of B16 tumour-bearing mice. These results indicate that F1/F3 may be effective to improve the efficacy of ICB and therapeutic vaccine-based immunotherapy for human epithelial cancers and warrants consideration for clinical trials.…”
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Poly-Systemic Analysis of Military Students’ Discipline by L. Ya. Dorfman, A. V. Dubrovsky, A. P. Andrunik, E. A. Tsariev, V. N. Lyadov

“…Confirmatory factor and comparative analysis were used to process the results obtained.Results and scientific novelty. For the first time, the poly-system origin of discipline has been revealed theoretically, logically and empirically. …”
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Effects of combining sensory-motor exercises with transcranial direct current stimulation on cortical processing and clinical symptoms in patients with lumbosacral radiculopathy: A... by Soheila Qanbari, Roya Khanmohammadi, Gholamreza Olyaei, Zohreh Hosseini, Hanie Sadat Hejazi

“…A linear mixed-effects model (LMM) analyzed group, time, and interaction effects, while Spearman's correlation assessed relationships between neurophysiological and clinical outcomes.…”
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Bibliometric analysis of research in ethical concerns and dilemmas of digital mental health care in the last two decades by Poonam Sharma, Rekha Wagani, Mahima Anna Varghese

“…With its core advantage of reaching the unreached, wider coverage, cost and time effectivity, all eyes are on the digital mental health care system. …”
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Removal of ceftriaxone and ciprofloxacin antibiotics from aqueous solutions using graphene oxide derived from corn cob by . Rinawati, A. Rahmawati, D.R. Muthia, M.D. Imelda, F.H. Latief, S. Mohamad, A.A. Kiswandono

“…This is in addition to the initial concentrations of 14 and 2 parts per million, the potential of hydrogen 4, and contact times of 50 and 40 minutes, respectively.CONCLUSION: In conclusion, adsorbents made from corn cobs are better at the removal of ciprofloxacin from water than the antibiotic ceftriaxone. …”
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