LoSI: Large Scale Location Inference Through FM Signal Integration and Estimation by Tathagata Mukherjee, Piyush Kumar, Debdeep Pati, Erik Blasch, Eduardo Pasiliao, Liqin Xu

“…We define and use Dominant Channel Descriptor (DCD) features, which can be used for positioning using time varying models. Finally we use an algorithm based on Euclidean nearest neighbors in the DCD feature space for position estimation. …”
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Whole exome sequencing identifies ABHD14A and MRNIP as novel candidate genes for developmental language disorder by Amal Bouzid, Malek Belcadhi, Amal Souissi, Meryam Chelly, Fakher Frikha, Hela Gargouri, Crystel Bonnet, Fida Jebali, Salma Loukil, Christine Petit, Saber Masmoudi, Rifat Hamoudi, Mariem Ben Said

“…We performed whole-exome sequencing (WES) of a first-time-described Tunisian-family with DLD. Analyses of segregation patterns with stringent filtering of the exome data identified disease-causing compound heterozygous variants. …”
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Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly by Alina A. Almaskhanova, Konstantin V. Melkozerov, Elena G. Przhiyalkovskaya, Natalia V. Tarbaeva, Anastasya Y. Korneluk, Raisa S. Kosharnaia, Victor Y. Kalashnikov, Zhanna E. Belaya, Galina A. Mel'nichenko, Natalia G. Mokrysheva

“…All patients underwent standard medical examinations, including hormonal blood tests, electrocardiograms, echocardiography, Holter monitoring electrocardiograms and magnetic resonance imaging (MRI) of the heart with gadolinium contrast, additionally 48 patients underwent T1-mapping, which is an MRI method that allows the detection of diffuse changes by measuring the values of myocardial relaxation time – T1. Results. The study revealed a high incidence of MF – 53 (75.7%) cases (21 women, 32 men). …”
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Biomarkers for Diagnosis and Prediction of Outcomes in Contrast-Induced Nephropathy by Justor Banda, Raquel Duarte, Therese Dix-Peek, Caroline Dickens, Pravin Manga, Saraladevi Naicker

“…Serum β2M levels were higher in CIN patients at all time points. Elevated baseline serum concentrations of IL18 (p<0.001), β2M (p=0.04), TNFα (p<0.001), and baseline urine KIM (p=0.01) and 24 h urine NGAL (p=0.02) were significantly associated with mortality. …”
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Nanopore-based random genomic sampling for intraoperative molecular diagnosis by Francesco E. Emiliani, Abdol Aziz Ould Ismail, Edward G. Hughes, Gregory J. Tsongalis, George J. Zanazzi, Chun-Chieh Lin

“…Furthermore, we validated iSCORED’s real-time applicability in 15 diagnostically challenging primary brain tumors, achieving 100% concordance in detecting aberrant CNV detection, including diagnostic chromosomal gains/losses and oncogene amplifications (10/10). …”
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Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses by Lifen Liu, Yang Liu, Rui Li, Yue Teng, Shuyang Zhao, Jinhong Chen, Changjiang Li, Xinyu Hu, Lin Sun

“…Anxiety and depression in a mice stress model were assessed using the open‐field test (OFT), elevated plus maze test (EPMT), and forced swimming test (FST). Real‐time quantitative PCR (qRT‐PCR) was conducted to validate key genes in stress‐exposed models. …”
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Diet management of older subjects with Oropharyngeal Dysphagia: The efficacy of ready-made texture-modified and fortified meals by Nikolina Jukic Peladic, Paolo Orlandoni, Laura Bartoloni, Giulia Giulioni, Claudia Venturini, Alessia Fumagalli

“…Ready-made products positively affected caregiving (75%), especially because the food administration was less time-consuming (90%). Conclusions: Ready-made texture-modified fortified food seem promising in ensuring the improvement in patients' safety and easing the caregivers' tasks. …”
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Review and External Evaluation of Population Pharmacokinetic Models for Vedolizumab in Patients with Inflammatory Bowel Disease: Assessing Predictive Performance and Clinical Appli... by Marija Jovanović, Ana Homšek, Srđan Marković, Đorđe Kralj, Petar Svorcan, Tamara Knežević Ivanovski, Olga Odanović, Katarina Vučićević

“…Furthermore, the models were utilized for Monte Carlo simulations to generate concentration–time profiles based on 24 covariate combinations specified within the models. …”
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Diagnostics and treatment of pancreatic exocrine insufficiency: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, A. V. Okhlobystin, S. A. Alekseyenko, Ye. V. Beloborodova, Yu. A. Kucheryavy, T. L. Lapina, A. S. Trukhmanov, I. B. Khlynov, M. V. Chikunova, A. A. Sheptulin, O. S. Shifrin

“…No standardized methods of pancreatic exocrine function assessment are developed at the present time, therefore standard diagnostic criteria of PEI are lacking. …”
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The Assessment of Different Dietary Selenium Resources on Reproductive Performance, Spawning Indicators, and Larval Production of Red Tilapia (Oreochromis mossambicus × O. niloticu... by Mohammed A. E. Naiel, El-Sayed H. Eissa, Yasmin M. Abd El-Aziz, Saadea Saadony, Heba E. Abd Elnabi, Salah El-Sayed Sakr

“…The findings showed that female fish fed NPSe-enriched diets had significantly higher viscera, liver, and gonad weight than other experimental groups. At the same time, the highest levels of LH, progesterone, and estradiol-17β, as well as the lowest levels of FSH, were detected in fish fed the NPSe diet, followed by those on the Na2SeO3 + NPSe and Na2SeO3 diets, respectively. …”
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Preoperative assessment of liver regeneration using T1 mapping and the functional liver imaging score derived from Gd-EOB-DTPA-enhanced magnetic resonance for patient with hepatoce... by Qian Li, Tong Zhang, Shan Yao, Feifei Gao, Lisha Nie, Hehan Tang, Bin Song, Bin Song, Yi Wei

“…ObjectivesTo explore whether T1 mapping parameters and the functional liver imaging score (FLIS) based on Gd-EOB-DTPA MRI could evaluate liver regeneration after hepatectomy for HCC patient.MethodsThis retrospective study finally included 60 HCC patients (48 men and 12 women, with a median age of 53 years). T1 relaxation time of liver before gadoxetic acid injection (T1pre) and during the hepatobiliary phase (T1HBP), reduction rate (Δ%) and FLIS were calculated, their correlations with liver fibrosis stage, hepatic steatosis, and liver regeneration, quantified as regeneration index (RI), were assessed by Kendall’s tau-b correlation test or Spearman’s correlation test. …”
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Navigating complex arterial reconstruction in living donor liver transplantation: the role of the splenic artery as a viable conduit by Hosam Hamed, Mohamed Elshobary, Tarek Salah, Ahmad M. Sultan, El-sayed Abou El-Magd, Ahmed M. Elsabbagh, Ahmed Shehta, Mohamed Abdulrazek, Waleed Elsarraf, Mohamed A. Elmorshedi, Mostafa Abdelkhalek, Usama Shiha, Hassan Magdy Abd El Razek, Mohamed Abdel Wahab

“…Results The splenic artery was used because of arterial dissection (70%) or inadequate arterial blood flow. Operative time ranged from 640 to 1020 min, and no splenic infarction was observed. …”
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Digital twin-based modeling of natural gas leakage and dispersion in urban utility tunnels [version 2; peer review: 2 approved] by Jiansong Wu, Jitao Cai, Ziqi Han, Yanzhu Hu, Ming Fu, Yuefei Li, Xin Wang, Xiaofu Zou

“…Based on this model, real-time integration of gas sensor data from utility tunnels is achieved through the DA algorithm. …”
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Longitudinal Assessment of Alterations in Peripheral Inflammatory Markers Over a Hospitalization Period in Patients with Schizophrenia by Süleyman Dönmezler, Oya Güçlü, İmren Kurt, Halil Ibrahim Ozturk

“…Inflammatory markers such as neutrophil-to-lymphocyte Ratios (NLR), monocyte-to-lymphocyte ratios (MLR), platelet-to-lymphocyte ratios (PLR), C-reactive protein-to-albumin ratios (CAR), and systemic immune inflammation indices (SII) were calculated at the time of hospital admission and after three weeks. …”
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Alcohol Relapse After Liver Transplantation: Risk Factors, Outcomes, and a Comparison of Risk Stratification Models by Karen Young, Yuval A. Patel, Benson Hoffman, Sarah Peskoe, Shein-Chung Chow, Karli Erhart, Jennifer Jackson, Stephanie Garbarino

“…Results: Sixty-seven patients with a median follow-up time of 43 months were included. Eighteen (27%) experienced alcohol relapse. …”
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Bridging past and present: exploring Cannabis traditions in Armenia through ethnobotanical interviews and bibliographic prospecting by Manica Balant, Teresa Garnatje, Daniel Vitales, Marine Oganesian, Joan Vallès, Nina Stepanyan-Gandilyan, Airy Gras

“…The loss of vernacular names over time, as detected in this study, also reflects the erosion of traditional knowledge, which correlates with diminishing use. …”
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SiCLAT: simultaneous imaging of chromatin loops and active transcription in living cells by Xin Wan, Jie Kong, Xiaodi Hu, Lulu Liu, Yuanping Yang, Hu Li, Gaoao Liu, Xingchen Niu, Fengling Chen, Dan Zhang, Dahai Zhu, Yong Zhang

“…This imaging system offers a novel means of directly observing cis-element interactions and the corresponding gene transcription in living primary cells, thus providing real-time imaging for comprehensive mechanistic investigations of dynamic enhancer-promoter or enhancer-enhancer interactions in regulating transcription activation within living cells.…”
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Phenolic Compounds and Pharmacological Potential of <em>Lavandula angustifolia</em> Extracts for the Treatment of Neurodegenerative Diseases by Olha Mykhailenko, Viktoriia Hurina, Nataliia Herbina, Yuliia Maslii, Liudas Ivanauskas, Inna Vladymyrova, Dmytro Lytkin, Zigmantas Gudžinskas, Hanna Severina, Olena Ruban, Victoriya Georgiyants

“…The selection of the optimal conditions for obtaining lavender herb extracts was determined on the basis of the results of the total yield of phenolic compounds in each extract, where it was found that the raw material–solvent ratio (1:10) in water and 50% ethanol gave the highest yield of substances; the preferred extraction time was 20 min, and the temperature was 60–70 °C, especially for water extraction. …”
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Temperature and repeated catecholamine surges modulate regional wall motion abnormalities in a rodent takotsubo syndrome model by Ermir Zulfaj, AmirAli Nejat, Abdulhussain Haamid, Aaron Espinosa, Ahmed Elmahdy, Tetiana Pylova, Sandeep Jha, Björn Redfors, Elmir Omerovic

“…Systolic function at initial echocardiography predicted worse outcomes (odds ratio 0.73; 95%CI 0.57–0.85), and RWMA extent correlated with recovery time (Rho = 0.772). TS rats developed complications similar to patients, including heart failure, arrhythmias, and thrombus formation. …”
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Exploring the inhibitory effect and mechanism of isorhamnetin therapy on oral squamous cell carcinoma based on network pharmacology and molecular docking by YU Fangfang, ZHOU Jingjing, YANG Jie, QU Huijuan, HUI Guangyan

“…Methods The key targets were obtained by constructing the PPI protein interaction network based on the common intersection targets of Iso-OSCC. At the same time, gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) were used to analyze the related signaling pathways of the intersection targets. …”
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