Toll-like receptor upregulation in liver and peripheral blood mononuclear cells of patients with amoebic liver abscess by Sandhya Khunger, Abhishek Mewara, Upninder Kaur, Ajay Duseja, Pallab Ray, Naveen Kalra, Navneet Sharma, Rakesh Sehgal

“…Aim: We aimed to understand the host and microbe interactions at the time of infection and inflammatory response in amoebic liver abscess (ALA) patients based on toll-like receptor (TLR) expression (mRNA), cytokine and IgG subtypes levels. …”
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Metasurface higher-order poincaré sphere polarization detection clock by Hui Yang, Kai Ou, Qiang Liu, Meiyu Peng, Zhenwei Xie, Yuting Jiang, Honghui Jia, Xinbin Cheng, Hui Jing, Yueqiang Hu, Huigao Duan

“…Our implementation opens up a new pathway towards real-time polarimetry of arbitrary beams featuring miniaturized size, a simple detection process, and a direct readout mechanism, promising significant advancements in fields reliant on polarization.…”
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Integrated movement models for individual tracking and species distribution data by Frances E. Buderman, Ephraim M. Hanks, Viviana Ruiz‐Gutierrez, Michael Shull, Robert K. Murphy, David A. W. Miller

“…In addition, the integrated approach (a) improves accuracy of other estimated movement parameters, (b) allows us to estimate the proportion of migratory and non‐migratory birds in a given location and time, and (c) estimate future spatiotemporal distributions of birds given a wintering location, which provide estimates of seasonal connectivity and migratory routes. …”
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Loss of phosphatase and tensin homolog (PTEN) increases Lysyl oxidase-like 2 (LOXL2) expression enhancing the growth of fallopian tube epithelial cells as three-dimensional spheroi... by Angela Russo, Junlone Moy, Manead Khin, Timothy R. Dorsey, Alfredo Lopez Carrero, Joanna E. Burdette

“…Conclusions: These results reveal for the first time that PTEN loss in FTE cells increases LOXL2 expression through downregulation of Pax2, and LOXL2 deletion blocks 3D spheroid formation.…”
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Clinical validation of a biopsy‐based six‐gene signature prognostic for aggressive prostate cancer by Agnieszka Krzyzanowska, Debra F. Higgins, Stephen Barron, Tony Loughman, Amanda O'Neill, Katherine M. Sheehan, Chan‐Ju Angel Wang, Bozena Fender, Leah McGuire, Joanna Fay, Anthony O'Grady, Des O'Leary, R. William Watson, Anders Bjartell, William M. Gallagher

“…The primary outcome of adverse pathology and secondary outcomes of high primary Gleason (≥G4) and high pathological T‐stage (≥T3) were assessed by likelihood ratio statistics and area under the receiver operating characteristic curves from logistic regression models; time to biochemical recurrence was assessed by likelihood ratio statistics and C‐indexes from Cox proportional hazard regression models. …”
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Effect of Buffer Charge Redistribution on RF Losses and Harmonic Distortion in GaN-on-Si Substrates by Pieter Cardinael, Sachin Yadav, Bertrand Parvais, Jean-Pierre Raskin

“…Free carrier transport across the buffer is shown to have the greatest contribution on the large time constants, highlighting the importance of vertical transport paths in GaN-on-Si stacks.…”
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Hydrophobic deep eutectic solvents as novel, sustainable aids for intracellular protein release from Saccharomyces cerevisiae by Tjalling Gijsbert Tjalsma, Yannick Patrice Didion, Ziran Su, Magdalena Malankowska, Pablo Torres-Montero, José Luis Martínez, Manuel Pinelo

“…Here, the use of hydrophobic deep eutectic solvents (DESs) as cell wall permeabilization agents for intracellular protein release from Saccharomyces cerevisiae was studied for the first time. This study examines the relatively new type V DESs, which favors downstream methods because less solvent is needed and environmentally friendly substances can be used. …”
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Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials by Jianyu Gan, Jiya He, Kaixiang Zhou, Zhangyuting Shang, Gengxin Dong, Dapeng Bao, Junhong Zhou

“…In the meta-regression, moderators such as the mean age, sex, and baseline BDNF levels of participants, as well as total TCEs time were not associated with outcome variables. …”
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Clinically meaningful improvements after gene therapy for aromatic L-amino acid decarboxylase deficiency (AADCd) in the Peabody Developmental Motor Scale, Second Edition (PDMS-2) a... by Wuh-Liang Hwu, Hui-Min Lee, John Devin Peipert, Rongrong Zhang, Christian Werner, J. Rafael Sierra, Thomas O’Connell, Jonathan J. Woolley, Marjorie Crowell, Antonia Wang, Ioannis Tomazos

“…Correlations between measures were of large magnitude and improved over time (Month 6: r = 0.599 [p = 0.0032]; Month 18: r = 0.796 [p = 0.0002]; Month 60: r = 0.861 [p = 0.0007]). …”
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An analysis of referral patterns of traumatic brain injury at Groote Schuur Hospital Trauma Centre by N Parker, T Navsaria, M Lopez, L Marineau, R Maine, K Chu, T Govender, D McPherson, P Navsaria

“…Three hundred and two (58.6%) were discharged home within 24 hours. The mean time between referral and CT scan was 13 hours. …”
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Modeling the thermal performance of hybrid paraffin-air nanostructure in a heat sink: Effect of atomic ratio of Al2O3 nanoparticles by Wed khalid Ghanim, Rassol Hamed Rasheed, Ahmed Shawqi Sadeq, Mohammad N. Fares, Soheil Salahshour, Rozbeh Sabetvand

“…Furthermore, the maximum temperature within the system increases to 934.17 K at the 3 % atomic ratio. The aggregation time at this concentration is 8.11 ns, which decreases to 6.83 ns at a 10 % atomic ratio, further supporting the detrimental impact of nanoparticle aggregation. …”
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Immunogenicity of recombinant fragment of orthopoxvirus p35 protein in mice by Ya. A. Khlusevich, A. L. Matveev, E. P. Goncharova, I. K. Baykov, N. V. Tikunova

“…In this work, recombinant protein р35Δ12 produced in E. coli cells XL1-blue and purified by chromatography was used for two-time immunization of mice. Two weeks after the second immunization, blood samples were taken from mice and serum antibodies were analyzed. …”
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Artificial intelligence driven clustering of blood pressure profiles reveals frailty in orthostatic hypertension by Claire M. Owen, Jaume Bacardit, Maw P. Tan, Nor I. Saedon, Choon‐Hian Goh, Julia L. Newton, James Frith

“…As physiological reserve diminishes with age, individuals grow more susceptible to such stressors over time, risking inadequate haemodynamic control observed in orthostatic hypotension. …”
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Gene–Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy by Farzana Jasmine, Armando Almazan, Yuliia Khamkevych, Maria Argos, Mohammad Shahriar, Tariqul Islam, Christopher R. Shea, Habibul Ahsan, Muhammad G. Kibriya

“…We report, for the first time, the significant associations of somatic DELs (many in STR regions) in NMSC tissue and As exposure with many dysregulated gene pathways. …”
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Dexamethasone Provides Effective Immunosuppression for Improved Survival of Retinal Organoids after Epiretinal Transplantation by Bikun Xian, Ziming Luo, Kaijing Li, Kang Li, Mingjun Tang, Runcai Yang, Shoutao Lu, Haijun Zhang, Jian Ge

“…Following this, we used immunofluorescence, real-time polymerase chain reaction, and flow cytometry to investigate the effects of DEX and RAP on cells in the retinal organoids. …”
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Oxyuris spp. Infection in Green Iguana (Iguana iguana) Under Different Cage Types by shelly kusumarini, Rafi Dzakir Ghalib, Garvasilus Privantio Tegar Virgiawan Huler, Reza Yesica, Nanis Nurhidayah, Haris Muhamad, Nuha Fairusya

“…The highest mean egg per gram (EPG) was found in the green iguana which kept in a loose cage / extensive (mean EPG [CI 95 %] = 14 799.21 [14 442.05 – 15 156.37]), followed by terrarium (mean EPG [CI 95 %] = 8 763.80 [8 436.30 – 9 091.30]), and iron-based cage (mean EPG [CI 95 %] = 1 433.42 [1 303.79 – 1 563.05], respectively. At the same time, there is a significant relationship (P<0,05) between the type of cage and the infection rate of Oxyuris spp. …”
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The influence of COVID-19 pandemic on secondary prevention in non-COVID patients with cardioembolic stroke by Lučić-Prokin Aleksandra L., Bogdanović Milan M., Pustahija Tatjana L., Stamenković Marija S.

“…Conclusion: Our results demonstrate preserved stroke care quality during the COVID-19 time period. It is crucial to carefully evaluate the possible causes of any ischemic stroke, anticoagulant therapy with direct oral anticoagulants is the mainstay of NVAF management of CS stroke with the dominance of apixaban and bridging therapy. …”
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A Case of Violent Suicide Attempt in a Context of Myxedema Psychosis following Radioiodine Treatment in a Patient with Graves’ Disease by Louise Todorov, Amel Ait Boudaoud, Rachel Pascal de Raykeer, Alina Radu, Khadija Lahlou-Laforêt, Frédéric Limosin, Cédric Lemogne, Sébastien Czernichow

“…The patient presented delirium symptoms at the time of self-stabbing, which was associated with persecutory delusions and auditory harm command hallucinations. …”
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Risk Factors for Postoperative Nausea and Vomiting After TACE: A Prospective Cohort Study by Yuzhu Wang, Xin Zhou, Guoping Li, Qianzhou Lv, Xiaoyu Li, Zhiping Yan

“…Including: gender, age, education, BMI, operation time, concomitant underlying diseases and drugs, preoperative limosis, history of nausea and vomiting, history of kinetosis, history of smoking or drinking, and occurrence of PONV. …”
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Primary Biliary Cirrhosis-Specific Antimitochondrial Antibodies in Neonatal Haemochromatosis by Daniel S. Smyk, Maria G. Mytilinaiou, Tassos Grammatikopoulos, A. S. Knisely, Giorgina Mieli-Vergani, Dimitrios P. Bogdanos, Diego Vergani

“…Anti-PDC-E2 responses in both infant and mother declined over time, being present 2 months after LT (mother and child) and absent 10 months later (mother) and 17 months later (child). …”
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