Predicting the exposure of mycophenolic acid in children with autoimmune diseases using a limited sampling strategy: A retrospective study by Ping Zheng, Ting Pan, Ya Gao, Juan Chen, Liren Li, Yan Chen, Dandan Fang, Xuechun Li, Fei Gao, Yilei Li

“…However, multiple blood sampling is required to calculate the area under the plasma concentration‐time curve (AUC), causing patient discomfort and waste of human and financial resources. …”
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Postoperative Lung Function Advantages in Pulmonary Segmentectomy for Early‐Stage Lung Cancer by Ernesto Crisafulli, Claudio Micheletto, Alessio Campisi, Emanuele Vocale, Chiara Schiena, Giulia Sartori, Gianluca Gaburro, Elide Felici, Maurizio Infante

“…Complete lung function evaluation for the study was available for 52 patients (26 matched pairs). The median time from lung resection to repeat spirometry was 35 months. …”
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Molecular characterization of a rare TP63 variant associated with split-hand/split-foot malformation 4 and incomplete penetrance: disruption of the p63-Dlx signaling pathway by Jianlong Zhuang, Yanqing Li, Yu’e Chen, Hegan Zhang, Shufen Liu, Manman Hu, Chunnuan Chen

“…Conclusion This study identifies, for the first time, the TP63 gene variant c.956G > A (p.Arg319His) as a causative factor for SHFM4 in Chinese individuals with incomplete penetrance. …”
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Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis by Fang-Chen Gong, Ran Ji, Yu-Ming Wang, Zhi-Tao Yang, Ying Chen, En-Qiang Mao, Er-Zhen Chen

“…ROC analyses identified nine genes—LRG1, ELANE, TP53, LCK, TBX21, ZAP70, CD247, ITK, and FYN—as potential new biomarkers for sepsis. Real-time PCR confirmed that the expression of seven of these genes was in accordance with the microarray results. …”
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Fusion Model Using Resting Neurophysiological Data to Help Mass Screening of Methamphetamine Use Disorder by Chun-Chuan Chen, Meng-Chang Tsai, Eric Hsiao-Kuang Wu, Shao-Rong Sheng, Jia-Jeng Lee, Yung-En Lu, Shih-Ching Yeh

“…This system is easy to implement in the clinical setting and can save a lot of time on setting up and experimenting while maintaining excellent accuracy to assist in mass screening of MUD.…”
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Mechanism of Fire Prevention with Liquid Carbon Dioxide and Application of Long-Distance Pressure-Holding Transportation Technology Based on Shallow Buried and Near-Horizontal Goaf... by Naifu Cao, Yuntao Liang

“…Under the influence of reverse wind flow and self-expansion and diffusion, the diffusion radius of the goaf is 150 m, and the maximum storage time of gaseous CO2 in the goaf is 27 h. Liquid CO2 was injected into the area with relevant presence of CO, an indicator of possible fires. …”
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TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma by Hongsheng Lu, Chumeng Zhu, Yanyun Ruan, Lilong Fan, Kena Wei, Zhaohui Yang, Qi Chen

“…Immunohistochemistry and quantitative real-time PCR (qRT-PCR) were used to examine the expression of TFE3, P62/SQSTM1, and LC3 in PTC and paracancerous tissues. …”
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Gemelos digitales pulmonares by Ana Fernández-Tena, Carlos Arnedo, Guillaume Houzeaux, Beatriz Eguzkitza

“…DTs integrate clinical data, high-resolution images, and mathematical models to simulate respiratory mechanics, gas diffusion, and fluid dynamics in real time. This technology improves diagnosis, treatment planning, and disease progression monitoring. …”
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Completion of the Central Italy daily precipitation instrumental data series from 1951 to 2019 by Gamal AbdElNasser Allam Abouzied, Guoqiang Tang, Simon Michael Papalexiou, Martyn P. Clark, Eleonora Aruffo, Piero Di Carlo

“…This study seeks to fill the gaps of 201 daily precipitation time series in Central Italy by localizing the approach used to generate the Serially Complete dataset for the Planet Earth (SC‐Earth). …”
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Retrospective Comparison of Postoperative Fascia Iliaca Block and Multimodal Drug Injection on Early Function of the Knee in Femoral Fractures Using Retrograde Intramedullary Naili... by Songtao Li, Ping Luo, Yuhu Huang, Huarong Xia, Wushu Wei, Wendun Wei, Tianyu Xia, Kai Xu

“…There was no significant difference shown in any of the demographic, fracture types, and operative time. All patients performed regular and voluntary knee rehabilitation and weight-bearing at home following the instruction from the orthopedic staff. …”
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Current Updates on Molecular Diagnostic Assays Used for Detection of <i>Candida auris</i>: A Systematic Review by River Chun-Wai Wong, Alfred Lok-Hang Lee, Ingrid Yu-Ying Cheung, Viola Chi-Ying Chow, Margaret Ip, Christopher Koon-Chi Lai

“…This review summarized the key updates on three categories, including (i) sample pre-extraction procedures and nucleic acid extraction, including magnetic, bead-beating, mechanical, chemical, thermal, and column-based protocols; (ii) commercial molecular assays; and (iii) laboratory-developed tests (LDTs). For real-time PCR, commercial molecular assays and LDTs showed sensitivity (ranging from 94.9% to 100% and 44% to 100%, respectively) and specificity (ranging from 98.2% to 100% and 92% to 100%, respectively). …”
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Ultrafast laser welding of transparent materials: from principles to applications by Xianshi Jia, Jinlin Luo, Kai Li, Cong Wang, Zhou Li, Mengmeng Wang, Zhengyi Jiang, Vadim P Veiko, Ji’an Duan

“…The welding strength and stability are also improvable through the implementation of real-time, in-situ monitoring techniques and the prompt diagnosis of welding defects. …”
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Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

“…The most commonly reported barriers within the above-mentioned categories were suboptimal healthcare networks and interprofessional communication pathways, time constraints, poor applicability of CPGs in real-world practice, lack of knowledge and skills, poor motivations and adherence, and inadequate reinforcement (eg, remuneration). …”
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Prevalence and influencing factors of regular physical activity among community-dwelling adults in Shaanxi province, 2018: an analysis of surveillance data by Yali TAO, Rina SA, Weihua WANG, Meng WU, Rong LIU, Lin QIU

“…ResultsOf all participants, 711 reported regular physical activity (10 minutes of leisure-time physical activity at least 3 days per week), with a weighted prevalence of 13.36%. …”
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Continuous-wave Laser on Er,Yb-Codoped Pentaborate Crystal by K. N. Gorbachenya, V. E. Kisel, R. V. Deineka, A. S. Yasukevich, N. V. Kuleshov, V. V. Maltsev, D. D. Mitina, E. A. Volkova, N. I. Leonyuk

“…We report, for the first time to our knowledge, a diode-pumped continuous-wave microchip Er,Yb:YMgB5O10 laser. …”
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Construction of novel pJRD215-derived plasmids using chloramphenicol acetyltransferase (cat) gene as a selection marker for Acidithiobacillus caldus. by Rui Wang, Chunmao Lin, Jianqiang Lin, Xin Pang, Xiangmei Liu, Chengjia Zhang, Jianqun Lin, Linxu Chen

“…<h4>Results</h4>Effective inhibitory effect of chloramphenicol on the growth of A. caldus was elucidated for the first time. The P2-cat gene cassette, including a chloramphenicol acetyltransferase gene (cat) from plasmid pACBSR and a promoter (P2) upstream of the tetracycline resistance gene on pBR322, was designed, chloramphenicol acetyltransferase was expressed in A. caldus, and the enzyme activity was assessed. …”
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The Impact of Heating Methods on Respiratory and Allergic Diseases in Preschool Children: A Repeated Cross-Sectional Survey Across Northern and Southern China by Chenyang Wang, Shaohua Li, Yan Zhang, Haixia Zhou, Peiwen Zhang, Wei Yu

“…However, limited research has explored the relationship between indoor heating methods and childhood illnesses over time or on a large urban scale, and particularly the relationship between heating methods and asthma or allergic rhinitis among preschoolers from 2010 to 2019. …”
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Medium Energy Electron Flux in Earth's Outer Radiation Belt (MERLIN): A Machine Learning Model by A. G. Smirnov, M. Berrendorf, Y. Y. Shprits, E. A. Kronberg, H. J. Allison, N. A. Aseev, I. S. Zhelavskaya, S. K. Morley, G. D. Reeves, M. R. Carver, F. Effenberger

“…The Medium Energy electRon fLux In Earth's outer radiatioN belt (MERLIN) model takes as input the satellite position, a combination of geomagnetic indices and solar wind parameters including the time history of velocity, and does not use persistence. …”
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Prevalence, risk factors, and cardiovascular disease outcomes associated with persistent blood pressure control: The Jackson Heart Study. by Gabriel S Tajeu, Calvin L Colvin, Shakia T Hardy, Adam P Bress, Bamba Gaye, Byron C Jaeger, Gbenga Ogedegbe, Swati Sakhuja, Mario Sims, Daichi Shimbo, Emily C O'Brien, Tanya M Spruill, Paul Muntner

“…<h4>Background</h4>Maintaining blood pressure (BP) control over time may contribute to lower risk for cardiovascular disease (CVD) among individuals who are taking antihypertensive medication.…”
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Comparison of the safety of remimazolam and propofol during general anesthesia in elderly patients: systematic review and meta-analysis by Xianchun Liu, Longyi Zhang, Li Zhao, Xuelei Zhou, Wei Mao, Linlin Chen, Hongyu Zhu, Ying Xie, Linji Li

“…Among other secondary outcomes, the remimazolam group had lower incidences of injection site pain, nausea and vomiting, and hypoxemia compared to the propofol group, and also had a shorter extubation time.ConclusionIn this meta-analysis, compared to propofol, remimazolam reduced the incidence of hypotension, bradycardia, and injection site pain during general anesthesia in elderly patients. …”
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