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49501
Data-Driven Model for the Prediction of Total Dissolved Gas: Robust Artificial Intelligence Approach
Published 2020-01-01“…In addition, ELM’s training process computational time is stated to be much shorter than that of SVM. …”
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49502
SOCIAL AND ECONOMIC DEVELOPMENT OF MAGADAN: FROM A PLANNED ECONOMY TO A MARKET ECONOMY (1960–2020)
Published 2024-12-01“…Archival data from 1960–1990, characterizing the city’s socio-economic development, were examined and are now introduced into scientific discourse for the first time. The findings reveal that during the planned economy era, Magadan experienced major growth, with integrated development across industries, population increase, and economic appeal driven by northern benefits provided by the government. …”
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49503
Novel Antibacterial 4-Piperazinylquinoline Hybrid Derivatives Against <i>Staphylococcus aureus</i>: Design, Synthesis, and In Vitro and In Silico Insights
Published 2024-12-01“…Notably, <b>5k</b> exhibited potent and selective activity against <i>S. aureus</i> (MIC 10 μM), with a dose- and time-dependent response and capability to affect cell membrane integrity. …”
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49504
Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases
Published 2021-01-01“…Thus, the quality and freshness of hBM-MSCs decrease over time after detachment from the culture dish. Especially, for neurological disease cell therapy, the deformability of BM-MSCs is particularly important in the brain for the development of microvessels. …”
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49505
Tolterodine is a novel candidate for assessing CYP3A4 activity through metabolic volatiles to predict drug responses
Published 2025-01-01“…Its activity could be determined by non-invasive and cost-effective assays, such as breath analysis, for the personalised monitoring of drug response. For the first time, we identify an isotopically unlabelled CYP3A4 substrate, tolterodine that leads to the formation of a non-toxic volatile metabolite, acetone, which could potentially be applied to monitor CYP3A4 activity in humans. …”
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49506
A modeling study to define guidelines for antigen screening in schools and workplaces to mitigate COVID-19 outbreaks
Published 2025-01-01“…If high sensitivity antigen tests (Detection limit: $$6.3\times {10}^{4}$$ 6.3 × 10 4 copies/mL) are deployed, it reaches 69.3% (95% CI: 66.5–72.5). …”
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49507
Deep learning based tractography with TractSeg in patients with hemispherotomy: Evaluation and refinement
Published 2025-01-01“…However, to our knowledge, we are the first to document cases in which TractSeg erroneously reconstructs (“hallucinates”) tracts that are known to have been surgically disconnected, and we found cases in which it implausibly continues tracts through obvious lesions. At the same time, TractSeg failed to reconstruct or undersegmented some tracts that are known to be preserved.We subsequently propose a refinement of TractSeg which aims to improve its applicability to data with pathologies, by using its Tract Orientation Maps as an anatomical prior in low-rank tensor approximation based tractography such that tracking is guaranteed to continue only where presence of the tract is directly supported by the data (“data fidelity”). …”
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49508
Comparative effectiveness of laparoscopic versus open colectomy in colon cancer patients: a study protocol for emulating a target trial using cancer registry data
Published 2025-01-01“…Further to the hazard ratio, we will also compute differences in the absolute risk (at 1, 3, and 5 years) and restricted mean survival time (up to 1, 3, and 5 years). A weighted Kaplan‒Meier curve will be used to compare five-year overall survival in both treatment arms. …”
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49509
ТHE BEGINNING OF THE WORLD ACCORDING TO HESIODS AS THE BIRTH OF PHILOSOPHICAL ONTOLOGY
Published 2024-12-01“…Already in the early theogony, in the Orphics and in Hesiod, we find a certain mythological-poetic and, at the same time, religious-philosophical model of the origin of the world and its first elements. …”
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49510
Experiences of Māori and Pacific women recruited into a pregnancy clinical trial in Aotearoa, New Zealand: a Kaupapa Māori qualitative study
Published 2025-01-01“…In contrast, the major barriers described were time pressures and the distance to the research facility.Conclusions Sixteen Māori and Pacific women who participated in a double-blinded randomised controlled trial shared that successful recruitment of Māori and Pacific women into clinical trials can be promoted by research flexibility participants’ whānau/family responsibilities, effective and culturally safe communication, and research teams striving to build and maintain relationships with participants throughout the trial.Trial registeration number Australian New Zealand Clinical Trials Registry, ACTRN12617001078347p. …”
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49511
Filles victimes, filles vicieuses, filles dangereuses
Published 2018-03-01“…In addition to the law, municipal bylaws regulate and organize health surveillance of youth prostitution. At the same time, the 19th century criminological theories of the Italian positivist school (Lombroso, Ferri, Garofalo) and the French School of Social Anthropology (Lacassagne, Tarde) combined gave birth during the inter-war period to the School of Modern Anthropology founded by Doctor Vervaeck. …”
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49512
A Collaborative and Scalable Geospatial Data Set for Arctic Retrogressive Thaw Slumps with Data Standards
Published 2025-01-01“…Their spatial distribution remains poorly characterised due to time-intensive conventional mapping methods. While numerous RTS studies have published standalone digitisation datasets, the lack of a centralised, unified database has limited their utilisation, affecting the scale of RTS studies and the generalisation ability of deep learning models. …”
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49513
Follicular Occlusion Syndrome — a Possible Option of Follicular-Retension Origin of Pilonidal Sinus
Published 2024-01-01“…At present, no recurrences have been noted in any of the cases, and the mean follow-up time was 14 ± 5.6 months (6–27 months). PSD as a manifestation of follicular occlusion syndrome is characterized by a more cranial and more superficial location of the cavity in the sacrococcygeal region. …”
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49514
Comprehensive performance evaluation of satellite-based and reanalysis rainfall estimate products in Ethiopia: For drought, flood, and water resources applications.
Published 2025-02-01“…New hydrological insights for the region: This study revealed that the performance of rainfall products varies over space and time and is heavily impacted by the diverse climate and topography of Ethiopia. …”
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49515
Clinical, Paraclinical, and Evolutionary Profiles of Kidney Failure in Gold Miners Hospitalized in a Nephrological Service in a Sub-Saharan African Country
Published 2020-01-01“…The average consultation/referral time for patients at the CHU-YO was 25.4 ± 14.9 days. …”
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49516
Commodity risk assessment of debarked conifer wood chips fumigated with sulfuryl fluoride from the US
Published 2025-01-01“…In particular, it is important to note that SF treatments are generally less effective in eliminating fungi than insects, the required parameters of the fumigation should be met at all points of the pile of wood chips and the time of storage of wood chips before treatment should be kept as short as possible because B. xylophilus can easily reproduce and spread throughout the pile under conducive conditions.…”
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49517
Determination of Modelling Error Statistics for Cold-Formed Steel Columns
Published 2020-01-01“…In this article, an attempt has been made to estimate the Modelling Error (ME) associated with compression capacity models available in international standards for different failure modes of compression members fabricated from Cold-Formed Steel (CFS) lipped channel sections. For the first time, a database has been created using test results available in the literature for compression capacities of CFS lipped-channel sections. …”
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49518
A Novel Chemically Modified Curcumin “Normalizes” Wound-Healing in Rats with Experimentally Induced Type I Diabetes: Initial Studies
Published 2016-01-01“…Additional studies indicated efficacy of 1% CMC2.24 over more prolonged periods of time up to 30 days.…”
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49519
Impact of Moderate to Severe Renal Impairment on Mortality and Appropriate Shocks in Patients with Implantable Cardioverter Defibrillators
Published 2010-01-01“…Severe but not moderate CKD is an independent predictor for time to first appropriate shock.…”
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49520
The power reliability event simulator tool (PRESTO): A novel approach to distribution system reliability analysis and applications
Published 2025-03-01“…Our findings show that this system reliably met 93 % of energy demand for essential non-heating and cooling loads, fully serving these loads in 84 % of events, despite the constraints of daily time-of-use bill management which limits the battery’s state-of-charge reserve. …”
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