Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies by Mengdi Zhang, Haiying Qiu, Zheyi Han, Yazhong Ma, Jingjing Hou, Jingwei Yuan, Haiyan Jia, Menglu Zhou, Hongjie Lu, Yan Wu

“…The effects of lenalidomide on melanoma were further verified through Western blotting, immunohistochemistry, immunofluorescence, and quantitative real-time polymerase chain reaction，using both in vitro cell experiments and in vivo melanoma mouse models. …”
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Ultrasonic-assisted extraction of luteolin from peanut shells using ionic liquid and its molecular mechanism by Liwei Niu, Siwen Zhang, Xiaoyu Si, Yuhan Fang, Shuang Wang, Lulu Li, Zunlai Sheng

“…Single-factor experiments were conducted to analyze the effects of ultrasonic power, extraction time, extraction temperature, IL concentration, and solid-to-liquid ratio on extraction efficiency. …”
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A Complementary Low Schottky Barrier Nonvolatile Bidirectional Reconfigurable Field Effect Transistor Based on Dual Metal Silicide S/D Contacts by Liu Xi, Ya Wang, Meile Wu, Lin Qi, Mengmeng Li, Shouqiang Zhang, Xiaoshi Jin

“…It is designed with Source floating gate (SFG) and drain floating gate (DFG) and adopts two kinds of metal silicide contacts to form complementary low Schottky barrier both between the S/D electrodes and the conduction band of silicon and between the S/D electrodes and the valence band of silicon at the same time. Instead of a program gate (PG) of conventional BRFET which needs independent power supply, the SFG and DFG of the proposed CLSB-NBRFET can be programmed by the CG itself. …”
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The effect of differences in the third domain of the glycoprotein E of tick-borne encephalitis virus of the Far Eastern, Siberian and European subtypes on the binding of recombinan... by I. K. Baykov, A. L. Matveev, L. A. Emelianova, G. B. Kaverina, S. E. Tkachev, N. V. Tikunova

“…Using Western blot analysis and surface plasmon resonance, it was shown that ch14D5 antibody has the highest affinity (KD= 1.7±0.5 nM) for the D3 domain of the TBEV of the “Sofjin-Ru” strain belonging to the Far Eastern subtype of the virus. At the same time, the affinity of ch14D5 antibody for similar D3 proteins derived from “Zausaev”, “1528-99” and “Absettarov” strains of the Siberian and European subtypes of TBEV was noticeably lower (KD= 25±4, 300±50, 250±50 nM, respectively). …”
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Simulation Research on the Influence of the Clearance to the Impact Contact Characteristics between Coal Gangue and the Clearance-Contained Tail Beam Structure by Yang Yang, Zhengyuan Xin, Qingliang Zeng, Zhihai Liu

“…In order to clearly grasp the accurate impact contact response law between coal gangue and the hydraulic support, the radial clearance in the pin shaft connection structure of the tail beam is considered for the first time in this paper. By constructing the theoretical contact model of the pin shaft connection, the difficulty of studying the interaction between coal gangue and the hydraulic support through theoretical solution is proved. …”
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Numerical comparison of aerodynamic performance between stationary and moving trains with varied-height windbreak wall under crosswind by Ru-Dai Xue, Xiao-Hui Xiong, Guang Chen, Xiao-Bai Li, Bin Liu

“…The results found that the error of aerodynamic loads between two simulation methods increases with the elevation of the windbreak wall’s height with the largest value observed in the tail car. Comparing the time-averaged pressure on the train body in the two simulation methods, the most notable disparity manifests in the head car. …”
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Assisting significance of lncRNA ASB16-AS1 in the early detection and prognosis prediction of patients with deep venous thrombosis by Menglan Li, Yingying Li, Dawei Zhang, Cheng Cheng, Meiying Yang, Xiuyin Zhang, Xinming Yu, Bo Lu, Min Wang

“…ASB16-AS1 was negatively correlated with prothrombin time (PT, r = -0.763), antithrombin level (AT, r = -0.711), and international normalized ratio (INR, r = -0.764), and showed positive correlation with fibrinogen (FIB, r = 0.793) and D-dimer (D-D, r = 0.731). …”
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Development of a reversed dispersive based graphene functionalized with multiwalled carbon nanotubes for detection of β2-agonists in pork by high-performance liquid chromatography by Ying-Wen Qian, Xia Hong, Cai-Xia Yuan, Xin-Kui Zhou, Hai-Ning He, Dong-Shuai Wang

“…It was analyzed after purification by high-performance liquid chromatography, the extraction time and the properties of the nanocomposite were optimized. …”
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A practical guide to FAIR data management in the age of multi-OMICS and AI by Douaa Mugahid, Jared Lyon, Charlie Demurjian, Nathan Eolin, Charlie Whittaker, Mark Godek, Douglas Lauffenburger, Sarah Fortune, Stuart Levine

“…However, these ambitious efforts are often limited by access to a variety of high-density intra-, extra- and multi-cellular measurements resolved in time and space and across a variety of perturbations. …”
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A Survey on Adversarial Attacks for Malware Analysis by Kshitiz Aryal, Maanak Gupta, Mahmoud Abdelsalam, Pradip Kunwar, Bhavani Thuraisingham

“…The survey highlights real-world adversarial evasion attacks on machine learning-based anti-malware engines under each taxonomical heading, demonstrating the evolution and refinement of these attack strategies over time. Our survey outlines current limitations and practical challenges in executing adversarial attacks against malware detectors in real-world environments. …”
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Oral nutritional supplements for gastric cancer – the review of current evidence by A. L. Potapov, V. E. Khoronenko, E. V. Gameeva, Zh. V. Khailova, A. D. Dorozhkin, V. Yu. Scoropad

“…After gastrectomy (GE) its administration reduces the time of recovery of bowel motor function and the duration of hospitalization. …”
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DEKARTIŠKASIS DIEVO ĮRODYMAS: PRIELAIDOS IR INTENCIJOS by Skirmantas Jankauskas

“…An attempt is being made to prove that namely this Proof of the Existence of God serves as the axis for the Meditations of Descartes, though the subsequent philosophy attributed a considerably greater significance to the cogito principle. At the same time, there is also supported the traditional attitude that the most important discovery of Descartes is precisely the cogito principle, which initiates the modern thinking. …”
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Modeling the Incident Solar Radiation of the City of N’Djamena (Chad) by the Capderou Method by Mahamat Hassane Babikir, Donatien Njomo, Mahamat Barka, Mahamoud Youssouf Khayal, Deli Goron, Venant Sorel Chara-Dackou, Tefouet Tiague Martial, Kamta Legue Daniel Romeo, Gram-shou Jean Paul, Nzadi Siwe Elie

“…This model allowed us to determine, over time, the component of global, direct, and diffuse solar radiation over a period that will cover the different seasons of the year. …”
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A <i>SMALL AUXIN UP-REGULATED RNA</i> Gene Isolated from Watermelon (<i>ClSAUR1</i>) Positively Modulates the Chilling Stress Response in Tobacco via Multiple Signaling Pathways by Duo Wang, Gangli Ma, Jia Shen, Xinyang Xu, Weisong Shou, Zhengying Xuan, Yanjun He

“…Subcellular localization analysis demonstrated that the protein is directed to both the nucleus and cytoplasm. Quantitative real-time PCR (qRT-PCR) analysis indicated that <i>ClSAUR1</i> is ubiquitously expressed across various watermelon tissues, with pronounced expression in the roots and leaves. …”
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Electroacupuncture for mild-to-moderate dry eye: study protocol for a multicentre, randomised, single-blind, sham-controlled trial by Yue Zhao, Guang Yang, Yun-Qiong Lu, Mei-Yan Li, Jue Hong, Yan-Ting Yang, Xue-Jun Wang, Xie-He Kong, Zhao Ma, Xin-Yun Huang, Yue-Lan Zou, Xing-Tao Zhou, Xiao-Peng Ma

“…The primary outcome is the change in the non-invasive tear break-up time (NIBUT) from baseline to week 4. The secondary outcomes include tear meniscus height, the Schirmer I test, corneal and conjunctival sensation, the ocular surface disease index, corneal fluorescein staining, the numerical rating scale and the Chinese DE-related quality of life scale.Ethics and dissemination The trial protocol and informed consent were approved by the Ethics Committee of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine (identifier: 2021–119), Shanghai Eye Disease Prevention and Treatment Center (identifier: 2022SQ003) and Eye and ENT Hospital of Fudan University (identifier: 2022014).Trial registration number NCT05552820.…”
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Comparative analysis of deep learning models for crack detection in buildings by S. Siva Rama Krishnan, M. K. Nalla Karuppan, Adil O. Khadidos, Alaa O. Khadidos, Shitharth Selvarajan, Saarthak Tandon, Balamurugan Balusamy

“…Abstract Life-time of the buildings is generally challenged by the act of nature. …”
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A patient-centered interactive voice response system for supporting self-management in kidney transplantation: design and field testing by Raheleh Ganjali, Raheleh Ganjali, Mahin Ghorban Sabbagh, Mahin Ghorban Sabbagh, Saeid Eslami, Saeid Eslami

“…However, decisions must be made about the thoroughness of the execution of each phase, taking into account time constraints.…”
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Structural, Optical, and Electrical Characterization of β-Ga2O3 Thin Films Grown by Plasma-Assisted Molecular Beam Epitaxy Suitable for UV Sensing by Abraham Arias, Nicola Nedev, Susmita Ghose, Juan Salvador Rojas-Ramirez, David Mateos, Mario Curiel Alvarez, Oscar Pérez, Mariel Suárez, Benjamin Valdez-Salas, Ravi Droopad

“…Reflection high-energy electron diffraction (RHEED) was used to monitor the surface quality in real time. Both in situ RHEED and ex situ X-ray diffraction confirmed the formation of single crystal β-phase films with excellent crystallinity on c-plane sapphire. …”
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Traumatic degloving injuries: a prospective study to assess injury patterns, management, and outcomes at a single center in northern India by Divij Jayant, Atul Parashar, Ramesh Sharma

“…Most patients had mild disabilities. Time away from work depended largely upon the site and severity of the injury. …”
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Cell-free DNA release following psychosocial and physical stress in women and men by A. S. Limberg, F. Berg, E. Köper, C. Lindgraf, C. Gevers, R. Kumsta, E. M. Hummel, D. A. Moser

“…In addition, cf-nDNA and cf-mtDNA were comparatively quantified in both plasma and saliva at four time points, 2 min before and 2, 15, and 45 min after stress induction. …”
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