Integration of physical and mental health services for children and young people with eating disorders and functional symptom disorders: discrete choice experiment by Efthalia Massou, Mike Basher, Sophie D. Bennett, Tamsin Ford, Saheli Gandhi, Isobel Heyman, Josefine Magnusson, Raj Mehta, Pei Li Ng, Sara O’Curry, Angus I. G. Ramsay, Naomi J. Fulop, Stephen Morris

“…For functional symptom disorders, time to diagnosis was valued most highly, followed by days missed from school while obtaining a diagnosis, reservations about seeing a mental health practitioner, and costs of diagnosis to the NHS. …”
Get full text

Biomarker microRNA-371a-3p - expression in malignancies other than germ-cell tumours by Gazanfer Belge, Markus Klemke, Bendix Hansen, Cansu Dumlupinar, Aylin Igde, Dirk Arnold, Hans Salwender, Christian Wülfing, Armin Soave, Klaus-Peter Dieckmann

“…Methods M371 serum levels were measured in 137 patients with NTM of 12 different neoplastic entities using the IVDR-certified M371-Test for quantitative real-time PCR. Median M371 serum levels and percentages of M371 level elevations were calculated for the entire NTM group and for entity-specific subgroups. …”
Get full text

Changing Characteristics of Sandstone Pore Size under Cyclic Loading by Jiaguang Kan, Guichen Li, Nong Zhang, Peng Wang, Changliang Han, Shun Wang

“…The peak area of the middle relaxation spectrum increases as pressure increases from 10 to 20 MPa, and a peak for the long relaxation time spectrum appears. (2) Under 0–10 MPa load, the spectral peak associated with a large pore moves left and decreases in area as pressure increases. …”
Get full text

Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…The main causes of death among the population of the Krasnodar Krai from diseases of the digestive system at a young age are alcohol consumption with unhealthy consequences. At the same time, people of older age groups die from a lack of prevention of ulceration and inadequate eradication of Helicobacter pylori in patients taking non-steroidal anti-inflammatory drugs and antiplatelet agents.…”
Get full text

Social issues in general practice – a survey assessing the interprofessional perspective of general practitioners and social workers regarding frequency, challenges, and needs by Tonia Gerber, Laura Diaz Hernandez, René Rüegg, Dunja Vetter, Andreas Zeller

“…The most frequently mentioned benefits of an increased collaboration from the GPs’ perspective were “improved quality of care (more time for medical issues)” (64.8%) and “improved mental health of patients” (55.6%). …”
Get full text

Faktor Risiko yang Berhubungan dengan Kejadian Infeksi Toksoplasma pada Ibu Hamil di RSUD Arifin Achmad Pekanbaru Tahun 2010-2013 by Rika Andriyani, Kiki Megasari

“…Multivariate analysis of variables obtained OR education is 4.344 (95% CI: 1804-16427) means that pregnant women with low education are at risk 4 times suffered from toxoplasmosis in pregnant women with high education.…”
Get full text

Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells by Carl D. Richards, Laura Izakelian, Anisha Dubey, Grace Zhang, Steven Wong, Karen Kwofie, Aatif Qureshi, Fernando Botelho

“…Oncostatin M stimulated IL-33 mRNA and IL-33 full length protein in C10 mouse type 2 alveolar epithelial cells in culture in time-dependent and dose-dependent fashion, whereas IL-6, LIF, IL-31, IL-4, or IL-13 did not, and TGFβ repressed IL-33. …”
Get full text

Inhibition of Corneal Neovascularization by Subconjunctival Injection of Fc-Endostatin, a Novel Inhibitor of Angiogenesis by Junko Yoshida, Robert T. Wicks, Andrea I. Zambrano, Betty M. Tyler, Kashi Javaherian, Rachel Grossman, Yassine J. Daoud, Peter Gehlbach, Henry Brem, Walter J. Stark

“…Corneas were digitally imaged at 5 time points. An angiogenesis index (AI) was calculated (vessel length (mm) × vessel number score) for each observation. …”
Get full text

Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated C. acnes-treated SZ95 sebocytes by Ji Yeon Hong, Yong Hee Choi, Yoon Jin Roh, Mi-Kyung Lee, Christos C. Zouboulis, Kui Young Park

“…The gene expression profile was determined using real-time polymerase chain reaction analysis, and protein expression was confirmed via western blotting and immunofluorescence. …”
Get full text

Who freezes her eggs and why? psychological predictors, reasons, and outcomes of social egg freezing by Julia Jeannine Schmid, Seraina Weber, Ulrike Ehlert

“…The women froze eggs mainly to gain time to fulfill their desire for conventional parenthood (59%), including finding the right partner and enabling a genetic relationship to the child. …”
Get full text

The Role of Dectin-1-Mediated M1 Macrophage Polarization in Cerebral Ischemia-Reperfusion Injury by Chen Zongyun, Lin Bixia, Ding Fadian, Hong Xiaoping, Chen Hongbin, Deng Yu, Liu Qicai, Ye Xiaoyi, Zeng Kai

“…Dectin-1, cleaved caspase-3, and Bax increased, while antiapoptosis molecule, Bcl-2, decreased at three appropriate time points (after 6 hours, 12 hours, and 24 hours). …”
Get full text

Clinical Features and Dynamics of T Cells-Related Markers in Immunocompetent Patients with Cytomegalovirus Hepatitis by Takuya Komura, Takashi Kagaya, Hideo Takayama, Masahiro Yanagi, Takatoshi Yoshio, Saiho Sugimoto, Michiko Nishino, Noriaki Orita, Yoshiro Asahina, Masashi Nishikawa, Shuichi Kaneko, Masashi Unoura

“…All patients had a good clinical course without liver failure or transition to chronic liver injury. The time to recover from liver injury ranged from 12 to 142 days (mean, 43.4 ± 28.7 days). …”
Get full text

Thermal enhancement using variable characteristics and tripartite diffusion features of solar aircraft wings in context of Reiner-Philippoff hybrid nanofluid passing through a para... by Esraa N. Thabet, A.M. Abd-Alla, S.M.M. El-Kabeir

“…The application of solar energy in manufacturing processes and thermal power has changed dramatically. This time, the analysis of solar radiation and the possible combination of solar radiation and nanotechnology to increase the efficiency of solar-powered aircraft becomes a significant area of research. …”
Get full text

Neurological post-COVID syndrome is associated with substantial impairment of verbal short-term and working memory by Jeyanthan Charles James, Hannah Schulze, Nadine Siems, Christian Prehn, Daniel R. Quast, Nadine Trampe, Ralf Gold, Simon Faissner

“…Neurologic PCS patients showed impaired mental flexibility as an executive subfunction, verbal short-term memory, working memory and general reactivity (prolonged reaction time). Multiple regression showed fatigue affected processing speed; depression did not. …”
Get full text

The role of eco-digital learning in enhancing the impact of IoT, blockchain, and artificial intelligence on green supply chain for SME internationalization by Faisol, Hestin Sri Widiawati, Risky Aswi Ramadhani, Bambang Agus Sumantri

“…The results indicate that the adoption of the Internet of Things demonstrates a significant positive effect (p = 0.0000, T-statistic = 4.6695), improving real-time monitoring and operational efficiency. Blockchain also positively affects SME internationalization (p-value = 0.0085, T-statistic = 2.6427), enhancing supply chain transparency and ensuring compliance with international standards. …”
Get full text

Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms by Mona Mahmoud, Peter Richter, Philipp Arnold, Michael Lebert, Andreas Burkovski

“…A higher concentration of BP (194.23 µg/ml) or longer exposure time (60 min at 158 J/cm2) effectively eliminated approximately ≥99.99 % of growing and persister cells. …”
Get full text

Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin by Bardees M. Foda, Bardees M. Foda, Annika E. Baker, Annika E. Baker, Annika E. Baker, Łukasz Joachimiak, Marzena Mazur, Richard R. Neubig, Richard R. Neubig, Richard R. Neubig

“…Here, we investigate the role of apoptosis and the protein pirin in CCG-257081-mediated suppression of drug resistance.MethodsUsing naïve and resistant mouse YUMMER melanoma cells, we studied the effect of the BRAF inhibitor Vem with or without CCG-257081 on real-time growth and apoptosis (activation of caspase, Propidium iodide (PI) staining, and PARP cleavage). …”
Get full text

Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes by Anne-Marie L. Wegeberg, Tina Okdahl, Tina Fløyel, Christina Brock, Niels Ejskjaer, Sam Riahi, Flemming Pociot, Joachim Størling, Birgitte Brock

“…Heart rate variability, time domain, and frequency domains were calculated from a 24-hour Holter electrocardiogram, while cardiac vagal tone was determined from a 5-minute electrocardiogram. …”
Get full text

Comparing the Effectiveness of Intra-articular Injection with Autologous Platelet-rich Plasma vs Hyaluronic Acid vs Platelet-derived Growth Factors in Early Osteoarthritis of Knee... by Vidya S Konana, Harish S Yallapura, Sriharsha Bettaswamy, Srinivas P Sivaram, Darshan G Thimmegowda

“…The patients were evaluated primarily with WOMAC scale improvement and secondarily by VAS at the time of getting the injection (0), at the end of 1 month, and at the end of 3 months. …”
Get full text

MicroRNA-28-5p Regulates Liver Cancer Stem Cell Expansion via IGF-1 Pathway by Qing Xia, Tao Han, Pinghua Yang, Ruoyu Wang, Hengyu Li, Jin Zhang, Xinfeng Zhou

“…However, the role of miRNAs in liver CSCs has not been fully elucidated. Methods. Real-time PCR was used to detect the expression of miR-miR-28-5p in liver cancer stem cells (CSCs). …”
Get full text