Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose by Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl

“…We now examined for the first time how LD-RT influences FLS and bone marrow-derived macrophages in co-culture systems of an experimental model of RA to reveal further mechanisms of immune modulatory effects of low and intermediate dose of ionizing radiation. …”
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Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma by Ni Wang, Hao-Jun Luo, Guo-Bing Yin, Chao-Ran Dong, Man Xu, George G. Chen, Zhi-Min Liu

“…Additionally, HIF-2α, TWIST, and CXCR4 mRNA expression were assessed in 30 PTCs, 10 nodular hyperplasia, and 10 normal thyroid tissue specimens using real-time RT-PCR. TWIST and CXCR4 mRNA expression levels were up-regulated in PTCs, and high mRNA expression of TWIST and CXCR4 was significantly correlated with LNM (P=0.005 and P=0.010, resp.). …”
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Development of an analytical method for the simultaneous determination of 22 Polycyclic Aromatic Hydrocarbons (PAHs) in maternal and umbilical cord blood by Swiha, Stéphanie, Pichon, Valérie, Fournier, Thierry, Gil, Sophie, Delaunay, Nathalie

“…The aim of this project was to develop a method enabling, for the first time, the simultaneous determination of 22 listed PAHs from small volumes (100 ${\mu }$L) of maternal serum and umbilical cord blood, including a sample pre-treatment reducing as far as possible the quantity of solvents used. …”
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Left hemiparesis due to space-occupying lesion in pregnancy by Luminto, Ekarini Aryasatiani, Mahendro Aji Panuntun, Bobby Wirawan Hassan, Tania Sananta, Arya Elbert Neil

“…The patient felt weak and fell in the bathroom 2 times, at the office and at home. The patient had a history of taking aspilet for 1.5 months due to a misdiagnosis as a stroke in a Type B hospital and stopped when she came to the obstetric emergency room at a Type A Hospital for the first time. …”
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Exploring predisposing factors of hearing loss in prematurely born children: A nationwide case-control study by Pei-Chen Tsao, Hung-Chih Lin, Shang-Po Shen, Yu-Chia Chang

“…Methods: This study enrolled 21,576 children born at < 37 weeks of gestation; 3,596 with HL and 17,980 with normal hearing born between 2002 and 2015, matched for sex, age at diagnosis, and enrollment time. Data were abstracted from the concatenation of three nationwide databases for overall risk factors till the diagnosis of HL. …”
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Dynamics of a mechanical system with nonlinear elastic suspension and spectral analysis of the results by V. A. Nekhaev, V. A. Nikolaev, A. N. Smalev, K. O. Seryakov

“…Numerical modeling of the system is performed, the results of which are analyzed by the method of spectral analysis, based on the representation of the correlation function on a small time interval by a square polynomial. As a result of the analysis, it is found that in the pre-resonant and resonant regions, the general solution should consist of three components: a subharmonic of the order of 1/3, the fundamental harmonic, and the third harmonic. …”
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Neuropilin 1 Mediates Keratinocyte Growth Factor Signaling in Adipose-Derived Stem Cells: Potential Involvement in Adipogenesis by Simona Ceccarelli, Cristina Nodale, Enrica Vescarelli, Paola Pontecorvi, Valeria Manganelli, Giovanni Casella, Maria Giuseppina Onesti, Maurizio Sorice, Ferdinando Romano, Antonio Angeloni, Cinzia Marchese

“…Here, we demonstrate for the first time that Neuropilin 1 (NRP1), a transmembrane glycoprotein expressed in ASCs acting as a coreceptor for some growth factors, is responsible for KGF-dependent pathway activation in these cells. …”
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Antibiotic-induced changes in the human gut microbiota for the most commonly prescribed antibiotics in primary care in the UK: a systematic review by Alastair D Hay, Alyson L Huntley, Karen T Elvers, Esther T van der Werf, Victoria J Wilson, Ashley Hammond, Lorna Duncan

“…Secondary outcome was the time for the microbiota to return to baseline.Results Thirty-one articles with low or unclear risk of bias showed that antibiotics impact the gut microbiota by causing rapid and diminished levels of bacterial diversity and changes in relative abundances. …”
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Narrow Dietary Niche With High Overlap Between Snow Leopards and Himalayan Wolves Indicates Potential for Resource Competition in Shey Phoksundo National Park, Nepal by Sandesh Lamichhane, Bikram Shrestha, Bhumi Prakash Chaudhary Tharu, Raj Kumar Koirala, Bishnu Prasad Bhattarai, Pratigyan Poudel, Binaya Adhikari, Gopal Khanal

“…However, a comprehensive understanding of resource competition will require further study on other axes of niche partitioning, including habitat and time. Nevertheless, the region's low prey richness means that, with increasing human influence, any reduction in wild prey or increase in livestock could intensify competition between snow leopards and wolves, which could have implications for livestock depredation.…”
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A Temporal and Dynamic Approach to Enjambments in French Versified Poetry from the 17th to the late 19th Century by Éliane Delente

“…The second part will rely on linear or dynamic grammars that have established that, in any discourse, whether spoken or written, morpho-syntactic units are processed as they unfold over time. This temporal and dynamic perspective, applied to versified poetry, involves the reader in a prospective phase of predictions and a retrospective phase of satisfaction or frustration followed by continuous readjustments, which are an integral part of interpretation. …”
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Construction of a poor prognosis prediction and visualization system for intracranial aneurysm endovascular intervention treatment based on an improved machine learning model by Chunyu Lei, Anhui Fu, Bin Li, Shengfu Zhou, Jun Liu, Yu Cao, Bo Zhou

“…The model identified 10 key variables: age, hypertension, preoperative aneurysm rupture, Hunt-Hess grading, Fisher score, ASA grading, number of aneurysms, intraoperative use of etomidate, intubation upon leaving the operating room, and surgical time. These variables were consistent with the results of logistic multivariate analysis.ConclusionsThe application of improved machine learning models for the analysis of patient clinical data can effectively predict the risk of poor prognosis following endovascular intervention for intracranial aneurysms at an early stage. …”
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Characterization of an Endemic Plant Origanum grosii from Morocco: Trace Element Concentration and Antihyperglycemic Activities by H. El hassouni, M. Bouhrim, R. El hajji, M. Bnouham, A. Ziyyat, A. Romane

“…The present investigation aims to characterize, for the first time, endemic Origanum grosii collected from the Taounate region, Morocco. …”
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The Impact of Pelvic Floor Muscle Strengthening on the Functional State of Women Who Have Experienced OASIS After Childbirth by Atėnė Simanauskaitė, Justina Kačerauskienė, Dalia Regina Railaitė, Eglė Bartusevičienė

“…After one year of performing PFM strengthening exercises, some women in the study group exhibited stronger PFM contractions (<i>p</i> = 0.076), while others held the contracted PFM for a longer time (<i>p</i> = 0.133). UI affected women in the control group more often (<i>p</i> = 0.019). …”
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Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma by Xiang-Ming Wang, Shang-Wei Chen, Gang Chen, Hua-Fu Zhou, Ting-Qing Gan, Jing-Jing Zeng, Zu-Yun Li

“…Here, we detected miRNA-33a-5p in 20 samples from patients with LUSCs and 20 matching non-LUSC specimens by in-house quantitative real-time PCR (RT-qPCR). Relationship between miRNA-33a-5p expression and clinicopathological traits was investigated from materials derived from miRNA sequencing and miRNA microarrays. …”
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Drug risk Factors Associated with a Sustained Outbreak of Clostridium difficile Diarrhea in a Teaching Hospital by Swapan K Nath, Suzette Salama, Devia Persaud, James H Thornley, Ian Smith, Gary Foster, Coleman Rotstein

“…Major risk factors implicated in the development of C difficile diarrhea in hospitalized patients were the following antimicrobial agents: ceftazidime (adjusted odds ratio [aor]=26.01, 95% ci 5.67 to 119.19, P=0.0001); cefuroxime (aor=5.17, ci 1.86 to 14.36, P=0.005); ciprofloxacin (aor=3.81, ci 1.05 to 13.79, P=0.04); and clindamycin (aor=15.16, ci 2.93 to 78.44, P=0.004). This is the first time that the use of ciprofloxacin has been linked to the development of C difficile diarrhea. …”
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Electrochemically-driven solid oxide tubular membrane reactor for efficient separation of oxygen and argon by Yuanhui Tang, Yutao Hu, Sisi Wen, Song Lei, Yakai Lin, Li Ding, Haihui Wang

“…Inspired by the principle that O2 can permeate through the electrolyte as oxygen ions (O2-) in a solid oxide electrolysis cell, for the first time, this study designed and developed an electrochemically-driven tubular inorganic membrane reactor to separate O2/Ar mixtures, achieving high-purity Ar (≥99.99 %). …”
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HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway by Min Zhao, Yao-Yao Bian, Li-Li Yang, Yan-Qi Chen, Ya-Jie Wang, Yan-Ting Ma, Yu-Qiong Pei, Wen-Lin Li, Li Zeng

“…Histopathology, flow cytometry, ELISA, real-time PCR, and Western blotting were used to further detect the related protein, M1/M2 polarization tendency, and PPAR-γ nuclear translocation. …”
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Investigation of Insulin-Like Growth Factor 2 mRNA Binding Protein 2 Gene Polymorphisms in Type 2 Diabetes Patients by Duygu Yolal Ertural, Ümit Çınkır, Nurcan Aras

“…The molecular analysis of rs1470579 and rs4402960 polymorphisms of IGF2BP2 gene of each individual was performed by using Real-Time PCR (Applied Biosystems) method. Relationships of genotypes and alleles frequency of IGF2BP2 polymorphisms and T2D were examined by "Chi-square" or "Likelihood ratio" tests.Results: As a result of the genotype and allele distributions; there was association between type II diabetes patients and control group for IGF2BP2 rs1470579 (A/C) gene polymorphism (p=0.0123). …”
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Optimizing Rehabilitation Strategy for Walking after Stroke： from Assisted Walking Training to Brain-Limb Cooperative Therapy by YAN Tiebin

“…It is also the primary goal when planning rehabilitation treatment plans with patients. For a long time, experts in the field of neurological rehabilitation have been exploring effective methods to accelerate the recovery of walking function after stroke. …”
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A Clinical Mentorship and Quality Improvement Program to Support Health Center Nurses Manage Type 2 Diabetes in Rural Rwanda by Aphrodis Ndayisaba, Emmanuel Harerimana, Ryan Borg, Ann C. Miller, Catherine M. Kirk, Katrina Hann, Lisa R. Hirschhorn, Anatole Manzi, Gedeon Ngoga, Symaque Dusabeyezu, Cadet Mutumbira, Tharcisse Mpunga, Patient Ngamije, Fulgence Nkikabahizi, Joel Mubiligi, Simon Pierre Niyonsenga, Charlotte Bavuma, Paul H. Park

“…Of 263 observed nurse mentee-patient encounters, mentor and mentee agreed on diagnosis 94.4% of the time. Similarly, agreement levels were high for medication, laboratory exam, and follow-up plans, at 86.3%, 87.1%, and 92.4%, respectively. …”
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