Circulating Th1, Th2, Th17, Treg, and PD-1 Levels in Patients with Brucellosis by Rongjiong Zheng, Songsong Xie, Qiong Zhang, Ling Cao, Shaniya Niyazi, Xiaobo Lu, Lihua Sun, Yan Zhou, Yuexin Zhang, Kai Wang

“…The patients’ immune function had not completely recovered in a short period of time during convalescence, so long-term follow-up of convalescent patients is needed.…”
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Analysis of 42 Years of Cosmic Ray Measurements by the Neutron Monitor at Lomnický štít Observatory by Imre Kisvárdai, Filip Štempel, Lukáš Randuška, Šimon Mackovjak, Ronald Langer, Igor Strhárský, Ján Kubančák

“…Lastly, the computed prediction power score of 0.22 for neutron flux in the context of geomagnetic field strength presents exciting possibilities for developing real‐time geomagnetic storm prediction models based on cosmic ray measurements.…”
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Assessing the Direct Impact of Typhoons on Vegetation Canopy Structure and Photosynthesis by Yaoyao Zheng, Simin Zhan, Zaichun Zhu, Sen Cao, Jiana Chen, Pengjun Zhao, Weimin Wang, Ranga B. Myneni

“…We developed random forest models based on satellite-observed leaf area index (LAI) and environmental data during typhoon-free periods to simulate LAI under non-typhoon conditions. The simulated LAI time series was then compared with the satellite-observed typhoon-affected LAI to assess the typhoon-induced canopy loss and recovery, which was then used to estimate the typhoon-caused photosynthesis loss and recovery with 2 widely used light-use efficiency models. …”
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Automated skin lesion detection and prevalence estimation in Tamanend's bottlenose dolphins by Colin J. Murphy, Melissa A. Collier, Ann-Marie Jacoby, Eric M. Patterson, Megan M. Wallen, Janet Mann, Shweta Bansal

“…Anthropogenic global change is occurring at alarming rates, leading to increased urgency in the ability to monitor wildlife health in real time. Monitoring sentinel marine species, such as bottlenose dolphins, is particularly important due to extensive anthropogenic modifications to their habitats. …”
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Validated HPLC method for simultaneous determination of azelastine hydrochloride fluticasone propionate and oxymetazoline in nasal mucosa and nasopharyngeal swabs from real human s... by Neven N. Mikawy, Nancy Magdy, Marwa H. Mohamed, Amira M. El-Kosasy

“…A good separation of the three proposed analytes with a short run time of 10 min was noted. Our method was validated according to FDA guidelines for bioanalytical validation methods. …”
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Study protocol of the PRINCESS trial—PReoperative INtermittent fasting versus CarbohydratE loading to reduce inSulin resiStance versus standard of care in orthopaedic patients: a r... by Markus W Hollmann, Abraham H Hulst, Benedikt Preckel, Jeroen Hermanides, Ayla Y Stobbe, Eline S de Klerk, Robert van Wilpe, Arthur J Kievit, Kee Fong Choi, Mireille F M van Stijn

“…Recent evidence suggests that time-restricted feeding (TRF), a form of intermittent fasting, improves IR in the general population, even after a short period of TRF. …”
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shRNA-interfered of Nrf2 reveals a critical role for Keap1-Nrf2 signaling pathway during effects of zearalenone induced oxidative stress in IPEC-J2 cells by Qun Cheng, Shu Zhen Jiang, Li Bo Huang, Wei Ren Yang

“…Results The study results showed that, compared with the Sh-Nrf2 group, ZEA significantly increased the apoptosis rate of IPEC-J2 in a time- and dose-dependent manner. Compared with the Sh-Nrf2 group, the activities of total superoxide dismutase and glutathione peroxidase and relative expressions of Keap1 at mRNA and protein level in the Sh-Nrf2+ZEA20 and Sh-Nrf2+ZEA40 groups were significantly reduced, the malondialdehyde level, and the fluorescence intensity around and within the nucleus of reactive oxygen species and Nrf2, and the relative expressions of Nrf2, quinone oxidoreductase 1, and hemeoxygenase 1 at mRNA and protein level significantly increased. …”
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Analisis Sentimen Maskapai Penerbangan Menggunakan Metode Naive Bayes dan Seleksi Fitur Information Gain by Arif Bijaksana Putra Negara, Hafiz Muhardi, Indira Melinda Putri

“…The user reviews contained on the pegipegi.com website are currently very large so this makes it difficult and time consuming to read in its entirety. Therefore sentiment analysis is designed to help classify reviews into positive or negative categories so that they can provide airline recommendations based on the number of review categories. …”
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Association between combined healthy lifestyles and infertility: a cross-sectional study in US reproductive-aged women by Xiaofeng Ye, Xiaoxia Song, Sihang Zhou, Guoqing Chen, Liping Wang

“…A healthy lifestyle score was created based on healthy diet (top two-fifths of the Healthy Eating Index-2015 score), low-to-moderate alcohol drinking (1–14 g/day), optimal waist circumference (less than 80 cm), adequate physical activity (at least 150 min of moderate-to-vigorous leisure-time exercise per week), and current nonsmoking. …”
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Association of real life postural transitions kinematics with fatigue in neurodegenerative and immune diseases by Robbin Romijnders, Arash Atrsaei, Rana Zia Ur Rehman, Lea Strehlow, Jèrôme Massoud, Chloe Hinchliffe, Victoria Macrae, Kirsten Emmert, Ralf Reilmann, C. Janneke van der Woude, Geert Van Gassen, Frédéric Baribaud, Teemu Ahmaniemi, Meenakshi Chatterjee, Bruno Kusznir Vitturi, Clémence Pinaud, Jérôme Kalifa, Stefan Avey, Wan-Fai Ng, Clint Hansen, Nikolay V. Manyakov, Walter Maetzler

“…Abstract Fatigue is prevalent in immune-mediated inflammatory and neurodegenerative diseases, yet its assessment relies largely on patient-reported outcomes, which capture perception but not fluctuations over time. Wearable sensors, like inertial measurement units (IMUs), offer a way to monitor daily activities and evaluate functional capacity. …”
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Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach by Pei Liu, Lin Xu, Jing-han Guo, Jin-hua Chang, Xi-gang Liu, He-fei Xue, Ru-xing Wang, Zhong-si Li, Guang-xin Miao, Cui-zhe Liu, Jian-yu Zhou

“…The current diosgenin analysis methods have the disadvantages of long analysis time and low sensitivity. The aim of the present study was to establish an efficient, sensitive ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach for pharmacokinetic analysis of diosgenin amorphous solid dispersion (ASD) using tanshinone IIA as an internal standard (IS). …”
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Effects of coal mine dust on lung function in rats by LIU Yang, LI Meng, LU Liyuan, WANG Ru, YANG He, ZHANG Huifang

“…The relative mRNA expressions of peroxisome proliferators-activated receptor gamma coactivator 1-alpha (PGC-1α) and mitochondrial transcription factor A (TFAM) were detected using real-time fluorescent quantitative polymerase chain reaction assay. …”
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Study of the Optimal Control of the Central Air Conditioning Cooling Water System for a Deep Subway Station in Chongqing by Xingyu Shu, Yu Dong, Jun Liu, Xinhua Xu

“…The results also demonstrate that the cooling water pipes release heat to the air in the corridor most of the time, and the released heat is larger than the absorbed heat. …”
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Use of a microbial supplement containing live bacteria <I>Bacillus subtilis</I> and their metabolites in dairy farming by O. Yu. Oparina, A. S. Krasnoperov, S. V. Malkov, A. I. Belousov, A. E. Chernitskiy, I. Yu. Vershinina

“…The phagocytic activity of neutrophils in animals of all groups changed slightly. At the same time, the phagocytic index increased by 2.5–3.2 times throughout the experiment, which indicated an increase in nonspecific resistance of the body. …”
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Determination of Electrolytes in Critical Illness Patients at Different pH Ranges: Whom Shall We Believe, the Blood Gas Analysis or the Laboratory Autoanalyzer? by Christopher Hohmann, Roman Pfister, Kathrin Kuhr, Julia Merkle, Julian Hinzmann, Guido Michels

“…All patients suffered an infarct-related cardiogenic shock and were intubated and not under therapeutical hypothermia at the time of blood collection. We used scatter plots to compare different distributions of sodium and potassium values between the methods. …”
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Protective Effect of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) against Vascular Dysfunction in Hyperglycemic Rats by Nurul Paramita, Brilliant C. Puspasari, Randika Arrody, Neng T. Kartinah, Trinovita Andraini, Julfiana Mardatillah, Hardiyanti Rusli, Dewi I. S. Santoso

“…A colorimetric assay was used to measure superoxide dismutase (SOD) activity and malondialdehyde (MDA) levels. Quantitative real-time polymerase chain reaction (PCR) was used to measure the expression of the receptor for advanced glycation end-products (RAGE) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB). …”
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Genome wide landscaping of copy number variations for horse inter-breed variability by Nitesh Kumar Sharma, Prashant Singh, Bibek Saha, Anuradha Bhardwaj, Mir Asif Iquebal, Yash Pal, Varij Nayan, Sarika Jaiswal, Shiv Kumar Giri, Ram Avatar Legha, T. K. Bhattacharya, Dinesh Kumar, Anil Rai

“…Also, three random CNVRs were validated with real-time polymerase chain reaction. These findings will aid in the understanding the horse genome and serve as a preliminary foundation for future CNV association research with commercially significant equine traits. …”
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Rancidity Estimation of Perilla Seed Oil by Using Near-Infrared Spectroscopy and Multivariate Analysis Techniques by Suk-Ju Hong, Shin-Joung Rho, Ah-Yeong Lee, Heesoo Park, Jinshi Cui, Jongmin Park, Soon-Jung Hong, Yong-Ro Kim, Ghiseok Kim

“…The acid, peroxide value, and transmittance spectra of perilla seed oil stored in two different environments for 96 and 144 h were obtained and used to develop prediction models for different storage conditions and time periods. Preprocessing methods were applied to the transmittance spectra of perilla seed oil, and multivariate analysis techniques, such as principal component regression (PCR), partial least squares regression (PLSR), and artificial neural network (ANN) modeling, were employed to develop the models. …”
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Differential expressed genes (DEGs) and differential alternative splicing genes (DASs) revealed the common pathologic mechanism of three bacterial pathogens to American eels (Angui... by Zihao Chen, Guanghua Sun, Songlin Guo

“…Together, we report for the first time a comparative analysis of pathogenicity and RNA sequencing for E. anguillarum, V. harveyi and V. vulnificus in the American eel. …”
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Halothermophilic Cas9 and dCas9 Interaction with Variety sgRNA In-silico by Kenny Lischer, Kholisoh Hayati, Muhammad Haykal Fabian, Fina Amreta Laksmi, Yudhi Nugraha, Hamdan Dwi Rizqi, Riri Fauziyya, Sarmoko, Mohd Shukuri Mohamad Ali

“…Molecular Docking has advantages such as cost-effectiveness and time efficiency in designing the optimal sgRNA length. …”
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