A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2– Metastatic Breast Cancer by Elizabeth J. Anderson, Lea E. Mollon, Joni L. Dean, Terri L. Warholak, Ayal Aizer, Emma A. Platt, Derek H. Tang, Lisa E. Davis

“…., consistency in results by liquid versus solid tumor sample, by the same method over time) in patients with HR+/HER2– advanced (locally unresectable) or metastatic disease (HR+/HER2– mBC) and explores performance (e.g., pairwise concordance, sensitivity, specificity, or predictive value) of respective mutation findings. …”
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Transforming lemon Peel into a sustainable reservoir of bioactives: A green osmotic dehydration strategy by Priyanka Prajapati, Chhavi Porwal, Meenakshi Garg, Neha Singh, Susmita Dey Sadhu, Rajni Chopra, Eram S. Rao, Aparna Agarwal, Mohd Saeed, Safia Obaidur Rab, Dipendra Kumar Mahato, Pradeep Kumar, Madhu Kamle, Abhishek Dutt Tripathi

“…Employing Response Surface Methodology (RSM) framework, pivotal variables—temperature (30–60 °C), exposure time (60–180 min), and sucrose concentration (50–70°Brix)—were optimized to enhance water loss (WL) and solid gain (SG) while safeguarding bioactive retention. …”
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Therapeutic Approaches in Mitochondrial Dysfunction, Inflammation, and Autophagy in Uremic Cachexia: Role of Aerobic Exercise by Yumei Zhang, Yuqing Liu, Xiao Bi, Chun Hu, Feng Ding, Wei Ding

“…Inflammation was identified via proinflammatory cytokines and NLRP3 inflammasome components using real-time PCR and western blotting. We found that CKD mice exhibited higher BUN and creatinine levels and more severe glomerulosclerosis in the glomeruli and renal tubulointerstitial fibrosis, relative to the Sham group; all these effects were relieved by aerobic exercise. …”
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Immersive virtual reality to assess unilateral spatial neglect in stroke patients: a preliminary study by Chloé Sauvage, Pierre Chaulet, Luana Rivas Lopez, Johanne Garbusinski, Pierre Cabaraux, Zachary Duvigneaud, Stéphane Baudry

“…Results: The number of cancelled targets out of 35 was 32.5 (3.5) for PP, 33 (4) for CVR, and 34 (2) for EVR (mean [SD]), with a significant difference between PP and EVR (p < 0.05). The time to complete the Bells Test was 186 (69) s for PP, 184 (65) s for CVR, and 170 (58) s for EVR, without differences between modalities (p > 0.05). …”
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The effect of educational intervention based on the mobile application on women’s knowledge, attitude, and practice on microplastics and health: study protocol for a randomized con... by Zahra Seifi, Fatemeh Zarei, Fazlollah Ahmadi

“…Data analysis will include descriptive statistics and inferential tests, such as independent t-tests and paired t-tests, to assess group differences and within-group changes over time. Discussion Implementing an educational intervention on knowledge, attitude, and practice (KAP) about MPs using a mobile application will be a first in Iran. …”
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Teachers’ responses to racism and racist bullying in Dutch primary schools by Karen M. A. Sieben-Aduful, Roy A. Willems, Trijntje Völlink, Nico van der Wiel, Maria Sapouna, Pieter de Bruijn, Gemma Blok, Gemma Blok, Arjan E. R. Bos, Arjan E. R. Bos, Giel van Lankveld

“…Since they spend a significant time of their daily life in school, teachers have a crucial role in providing a safe and bias-free environment for these children. …”
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Transient response and analytical solution of burst phenomenon in long distance water pipeline by Zhi-Guo Tao, Ling Zhou, Yun-Jie Li, Yuan Huang, Yan-Qing Lu, Yin-Ying Hu, Rui-Ling Feng

“…The rapid detection and localisation of pipe burst incidents in water pipe systems are crucial for timely repair, minimisation of leakage, and assurance of water supply security. …”
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Profile of Progesterone Levels After Administration of Gonadotropins in Dairy Cattle with Ovarian Hypofunction by Erprinanda Galuh Berliana, Suzanita Utama, Wurlina Wurlina, Pudji Srianto, Tita Damayanti Lestari, Hermin Ratnani

“…As a result, the average time of heat in ovarian hypofunction cows was 7,4 days. …”
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The role of L.M. Karakhan in the Chinese policy of the Soviet Union (1923–1926) by I. N. Sotnikova

“…At the same time, the ambassador took an active part in organizing and supporting the revolutionary movement in China. …”
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Transcripts of Anthocyanidin Reductase and Leucoanthocyanidin Reductase and Measurement of Catechin and Epicatechin in Tartary Buckwheat by Yeon Bok Kim, Aye Aye Thwe, YeJi Kim, Xiaohua Li, Jin Woong Cho, Phun Bum Park, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Sun-Ju Kim, Tastsuro Suzuki, Kwang Hyun Jho, Sang Un Park

“…Gene expression was carried out by quantitative real-time RT-PCR, and catechin and epicatechin content was analyzed by high performance liquid chromatography. …”
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Evaluation of a pilot family planning educational seminar and subsequent attitudes towards family planning among Muslim communities in Tanzania. by Alexandra A Cordeiro, Hajirah Gumanneh, Aneth Nzali, Valencia J Lambert, Amina Yussuph, Albert Kihunrwa, Yassin Mchondo, Ramadhan Mtita, Hidaya Yahaya, Samuel E Kalluvya, Joyce Wamoyi, Mehrunisha Suleman, Jennifer A Downs, Agrey H Mwakisole

“…Empowering women and men to choose the number and timing of children is a global goal and enhances both maternal and child health. …”
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Designing an intervention to improve cognitive evaluations in primary care by Kyra S. O’Brien, Kristin Harkins, MaryAnne Peifer, Melanie Kleid, Cameron Coykendall, Judy Shea, Jason Karlawish, Robert E. Burke

“…Results Twenty PCPs were interviewed and mentioned barriers included lack of expertise to perform or interpret an assessment, time pressures, lack of incentives, competing priorities, lack of decision-making supports, and limited access to dementia specialists. …”
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Classification of kinesiophobia in patients after cardiac surgery under extracorporeal circulation in China: latent profile and influencing factors analysis from a cross-sectional... by Qi Li, Rong Wang, Yanmei Gu, Tong Ren, Jing Jing Piao, Wenhui Xing, Yujing Liang

“…The result of regression equation shows postoperative time (p&lt;0.001), age, self-efficacy, pain and social support level (p&lt;0.05) were the factors influencing the potential profile classification of patients after cardiac surgery under extracorporeal circulation.Conclusion The study identified three distinct classifications of patients: the low kinesiophobia group, the moderate kinesiophobia—high-risk perceived symptoms group and the high kinesiophobia—high exercise avoidance group (HK-HEAG). …”
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Determinants of Cesarean Section Deliveries in Public Hospitals of Addis Ababa, Ethiopia, 2018/19: A Case-Control Study by Areaya Gebreegziabher Hailu, Tsegaye Kebede Fanta, Fissaha Tekulu Welay, Natnael Etsay Assefa, Surafel Aregawi Hadera, Gebrekiros Aregawi Gebremeskel, Hagos Weldeslassie Gebremedhin, Guesh Gebreayezgi Asefa

“…The cases were all mothers who delivered through caesarean section, and controls were all mothers who delivered vaginally in the same time in the study area. Data were collected from the randomly selected women and looking into their cards. …”
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Effect of Neck Exercises Combined with Stimulating Baihui and Yongquan Acupoints Based on the Concept of Muscle and Bone Balance on Patients with Cervical Hypertension by CHEN Xiuming, LIN Jian, LIU Jinyong, FANG Yuelong, ZHAN Zhengxuan, HE Zhen, CAI Shuhe

“…Patients completed three sets of exercises each time, three times a day, continous treatment for 14 days. …”
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SIRT5‐mediated HOXA5 desuccinylation inhibits ferroptosis to alleviate sepsis induced‐lung injury by Lei Wang, Heng Fan, Min Sun, Ji‐Hui Ye

“…HOXA5, ferroptosis suppressor protein 1 (FSP1), sirtuin 5 (SIRT5), and glutathione peroxidase 4 (GPX4) expressions were measured using western blotting and Real‐Time Quantitative Polymerase Chain Reaction (RT‐qPCR. …”
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Fabrication of taxifolin loaded zein-caseinate nanoparticles and its bioavailability in rat by Ying Li, Hang Su, Wenjun Wang, Zhongping Yin, Jing’en Li, En Yuan, Qingfeng Zhang

“…After oral administration, taxifolin and its five metabolites were identified in rat plasma by ultra high performance liquid chromatography (UPLC) with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS). …”
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The transcription factor dFOXO controls the expression of insulin pathway genes and lipids content under heat stress in <i>Drosophila melanogaster</i> by M. A. Eremina, P. N. Menshanov, O. D. Shishkina, N. E. Gruntenko

“…Thus, we may conclude that dFOXO takes part in regulating the IIS pathway response to heat stress as well as the changes in lipids content caused by heat stress, and this regulation is mediated by DILP6. At the same time, the feeding behaviour of imago might be controlled by dFOXO and DILP6 under normal conditions, but not under heat stress.…”
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Air Pollution and COPD: Unveiling Hidden Risks of Mortality, Mechanical Ventilation, and Prolonged Hospitalization by Jovan Javorac, Dejan Živanović, Miroslav Ilić, Ana Milenković, Emilija Vujičić, Dragica Kovačević, Jelena Zvekić-Svorcan, Darko Mikić, Svetlana Stojkov, Jasminka Bačevac Eminović, Marija Jevtić

“…This study examines the influence of short-term air pollution exposure on adverse hospitalization outcomes—mortality, mechanical ventilation use, and prolonged hospitalization—in patients with non-infectious severe AECOPD in Novi Sad, Serbia. Using a five-year time-series analysis, concentrations of selected air pollutants (PM₁₀, PM_2.5, SO₂, and NO₂) and meteorological data were integrated with hospitalization outcomes. …”
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Aggregation‐based dual‐target probe for dual‐colour super‐resolution monitoring mitophagy and evaluating drugs regulating mitochondria by Xiu‐Zhi Yang, Hongbao Fang, Shumeng Li, Chengyan Chu, Yunhua Zhang, Ying Yang, Weijiang He, Yuncong Chen, Zijian Guo

“…This work provides a powerful dual‐colour super‐resolution imaging agent for real‐time monitoring the dynamics of organelle interactions and oxidative stress.…”
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