A remarkable and durable response to tislelizumab treatment of an anaplastic thyroid carcinoma without targetable genomic alterations: a case report by Jingjing Chai, Jiaqi Lv, Jian Xiong, Xiuwen Chen, Senyuan Luo, Zhiguo Luo, Zhiguo Luo, Ming Luo

“…Anaplastic thyroid carcinoma (ATC) is a rare and highly aggressive malignancy characterized by a poor prognosis, with a median survival time of approximately 3 to 4 months. In this report, we present a case involving a 59-year-old patient diagnosed with ATC, who experienced swift local recurrence and pulmonary metastasis following radical thyroidectomy. …”
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Hospital utilization and telemedicine preferences in patients with late-stage Parkinson’s disease and caregivers by Seo Hyun Hong, Seoyeon Kim, Seungmin Lee, Bora Jin, Jung Hwan Shin, Kyung Ah Woo, Han-Joon Kim

“…Descriptive analysis was conducted based on HY stage, age, and travel time to the hospital. Results: 82.1% of patients in HY4 make more than 50% of in-person visits by themselves or with caregivers, compared with only 38.9% of patients in HY5. …”
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Long-term outcomes of Türkiye’s first population-based mammography screening program: a decade of breast cancer detection and survival analysis in Bahçeşehir by Beyza Ozcinar, Erkin Aribal, Neslihan Cabioglu, Sibel Ozkan Gurdal, Gamze Varol, Nuran Akyurt, Efe Sezgin, Vahit Ozmen

“…The risk of breast cancer was 1.39 times higher (95% CI: 1.01–1.93) in women aged ≥ 50 compared to those less than 50 years (p = 0.045). …”
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Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small Cell Lung Cancer: A Real-Life Study at a Portuguese Centre by Maria João Santos, Filipa Ferro, Andrea Machado, Ana Sofia Vilariça, Direndra Hasmucrai, Paula Alves

“…Median overall and progression-free survival were 12.2 months and 6.7 months, respectively. At the time of the cut-off, 21.2% of patients were alive and progression-free. …”
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Urinary Tract Infections in Children: Changing Trends in Etiology and Local Resistance Patterns over a Three-Year Period by Patrícia Sousa, Lucinda Delgado, Susana Correia-de-Oliveira, Cecília Pereira, Ângela Dias, Ana Cláudia Tavares

“…Methods: We conducted a cross-sectional study including pediatric patients performing urine cultures in a hospital in northern Portugal over two periods: 2019 (group 1) and 2022 (group 2). Between time periods, an internal guideline was implemented recommending cefuroxime as the first-line choice for empirical treatment of urinary tract infections, according to local resistance patterns. …”
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Penerapan Simple Additive Weighting pada Pemilihan Canvasser Terbaik PT.Eratel Prima by Veny Cahya Hardita, Ema Utami, Emha Taufiq Luthfi

“…But this assessment process done with manual method and for data process require more time.  In addition, the assessment is still subjective and not relevant with actual situation. …”
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Bias in Discontinuous Elevational Transects for Tracking Species Range Shifts by Shixuan Li, Jiannan Yao, Yang Lin, Siyu Wu, Zhongjie Yang, Chao Jin, Yuhan Zhang, Zhen Wang, Jinliang Liu, Guochun Shen, Mingjian Yu

“…Our analysis focused on how quadrat spacing and survey time intervals affect bias in estimating species range shifts. …”
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The Urinary Liver-Type Fatty Acid Binding Protein (L-FABP) in Early Detection and Outcome Prediction of Sepsis-Associated Acute Kidney Injury by Ghi Nguyen Hai, Binh Nguyen Gia, Hoa Do Thanh, Cuong Nguyen Thai, Duc Vu Anh, Anh Duong Duc, Duong Le Xuan Xuan

“…Urinary L-FABP levels were measured at the time of admission and patients were classified into AKI and non-AKI groups within 7 days according to the KIDGO Criteria. …”
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Cryopreservation of primary neonatal rat oligodendrocytes and recapitulation of in vitro oligodendrocyte characteristics by Hanki Kim, Hanki Kim, Bum Jun Kim, Bum Jun Kim, Seungyon Koh, Seungyon Koh, Seungyon Koh, Hyo Jin Cho, Byung Gon Kim, Byung Gon Kim, Jun Young Choi, Jun Young Choi

“…Primary culture methods for OLs from rats have been developed and improved over time, but there are still multiple aspects in which efficiency can be boosted.MethodsTo make use of excess oligodendrocyte progenitor cells (OPCs) from primary cultures, a cryopreservation process utilizing a commercially available serum-free cryopreservation medium was established to passage and freeze OPCs at −80°C for later use.ResultsCryopreserved OPCs stored for up to 6 months were viable, and retained their OL lineage purity of ~98%. …”
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Classification by production: an alternative criterion to categorization by Luis Yáñez, Nidia Rojas, Ricardo Aparicio, Manuel Mazzei, Eugenio Maldonado, Jairo Fernández, Nicola Fabbozzo, Rafael Rincón, Rafael Urdaneta

“…In the absence of an institution in charge of the Stud Book, over time, this scarce information was lost to the point where it was impossible to recover it. …”
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A Mobile App–Based Gratitude Intervention’s Effect on Mental Well-Being in University Students: Randomized Controlled Trial by Chloë Fuller, Silvia Marin-Dragu, Ravishankar Subramani Iyer, Sandra Melanie Meier

“…Participants in the control group used only the mobile sensing app, which passively collected smartphone sensory data on mobility, screen time, sleep, and social interactions. …”
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Thermal properties and non-bonded interactions in human PMP2 variants: A molecular dynamics study by Prabin Aryal, Jhulan Powrel

“… Charcot-Marie-Tooth disease has been known for a long time, affecting population worldwide. Many studies on this disease have been conducted, including clinical as well as computational, but no effective medical cure has yet been found. …”
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Risk Probability Assessment of Annual Extreme Precipitation in Fujian by Yang Xinyu, Zhang Rongyan, Xu Hong, Wu Dixi

“…This methodology facilitates the characterization of extreme precipitation patterns across both time and space. To assess the risk of precipitation-driven disasters, the two-dimensional joint exceedance probability of extreme precipitation indices is calculated, and the empirical orthogonal function (EOF) method is employed to analyze the spatiotemporal evolution of extreme precipitation events in the region. …”
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Rutin via Increase in the CA3 Diameter of the Hippocampus Exerted Antidepressant-Like Effect in Mouse Model of Maternal Separation Stress: Possible Involvement of NMDA Receptors by Maryam Anjomshoa, Shakiba Nasiri Boroujeni, Sorayya Ghasemi, Zahra Lorigooini, Ahmad Amiri, Shima Balali-dehkordi, Hossein Amini-khoei

“…Rutin significantly reduced immobility time in the FST. The expression of NR2A and NR2B subunits of NMDA receptor in MS mice was significantly higher than that in the control group. …”
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Identification and characterization of Faecalibacterium prophages rich in diversity-generating retroelements by Anastasia Gulyaeva, Lei Liu, Sanzhima Garmaeva, Marloes Kruk, Rinse K. Weersma, Hermie J. M. Harmsen, Alexandra Zhernakova

“…DGRs of two phages were active at the time of the induction experiments, as evidenced by nucleotide variation in sequencing reads. …”
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Neglected Forearm Fractures and Its Outcome Following Mediolateral Plate Osteosynthesis: A Retrospective Case Series by Sitsabesan Chokkalingam, Ashok T Ramanathan, Gopinath Menon

“…The mean age in this study group is 32.4 years, with an average time delay of 3.8 months in presentation for the definitive procedure. …”
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Efficacy of Red Cell Salvage Systems in Open Acetabular Surgery by S. MacDonald, C. Byrd, E. Barlow, V. K. Nahar, J. Martin, D. Krenk

“…Our study revealed that patients with blood loss of less than 400 mL were 13 times less likely to receive autologous blood, and patients with hemoglobin less than 10.5 were 5 times less likely to receive autologous transfusion (p<0.05). …”
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Anxiety as a prevailing factor of performance of university mathematics students during the COVID-19 pandemic by D. Mendoza, M. Cejas, G. Rivas, C. Varguillas

“…Teaching mathematics at university in online format requires the assessment of digital connection and time limited submission of assignments. These factors limit understanding and generate mathematical anxiety. …”
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Personal culture as a goal of continuing developmental education: Philosophical and methodological substantiation by N. L. Hudyakova, A. B. Nevelev, V. S. Neveleva

“…The scientific novelty of the study lies in the fact that for the first time in the philosophy of education, the authors consider the formation of personal culture in conjunction with the development by individuals of groups of cultural means corresponding to the main stages of human cultural development.Practical significance. …”
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The potential uses of Galangal (Alpinia sp.) essential oils as the sources of biologically active compounds by R. Amilia Destryana, Teti Estiasih, Sukardi, Dodyk Pranowo

“…This genus has been used for a long time in traditional medicine in some countries along with for food flavouring and spices. …”
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