Nuciferine relieves type 2 diabetes mellitus via enhancing GLUT4 expression and translocation by Tongxi Zhou, Guanjun Song, Di Tian, Qinghua Liu, Jinhua Shen, Xinzhou Yang, Ping Zhao

“…A laser scanning confocal microscope was used to track the translocation of glucose transporter 4 (GLUT4) in L6 cells and the changes in intracellular Ca2+ levels in real time, and related protease inhibitors combined with western blotting were used to explore the mechanism of nuciferine. …”
Get full text

Characterization of the Interaction of a Novel Anticancer Molecule with PMMA, PCL, and PLGA Polymers via Computational Chemistry by Edwar D. Montenegro, Jamylle M. Nunes, Igor F. S. Ramos, Renata G. Almeida, Eufrânio N. da Silva Júnior, Márcia S. Rizzo, Edson C. da Silva-Filho, Alessandra B. Ribeiro, Heurison S. Silva, Marcília P. Costa

“…The development of anticancer drugs is costly and time intensive. Computational approaches optimize the process by studying molecules such as naphthoquinones. …”
Get full text

Overcoming the Silencing of Doxycycline-Inducible Promoters in hiPSC-derived Cardiomyocytes [version 1; peer review: 1 approved, 2 approved with reservations] by Michelle Guichardaz, Elisa Balmas, Alessandro Bertero, Sveva Bottini

“…Transgene expression was assessed via flow cytometry and real-time quantitative PCR. Results TRE3VG exhibited higher activity than T11, but both were prone to silencing. …”
Get full text

Assessment of environmental impacts of heavy metal pollution in rice in Nanning, China by Jing Zhang, Peng Li, Siyan Li, Zhongqi Lyu

“…However, since the pollution of heavy metals will continue to enrich the food chain with time, long-term use will also cause harm to the human body. …”
Get full text

A New X-Ray and Radio Burst Activity from the Magnetar SGR 1935+2154 by Noor S. Rehan, Alaa I. Ibrahim

“…SGR 1935+2154 has emerged as the most active magnetar in recent years, exhibiting X-ray burst activity nearly annually and emitting a fast radio burst (FRB 200428 (FRB1)) in its 2020 April activity, for the first time from a Milky Way source, accompanied by an X-ray burst (X _FRB1 ). …”
Get full text

Classification of Emerging Scoliosis in Congenital Scoliosis After Hemivertebra Resection and Short Segmental Fusion by Chenkai Li, Xiaohan Ye, Bingtai Han, You Du, Yiwei Zhao, Dihan Sun, Shengru Wang, Jianguo Zhang

“…The mean age of the ES patients at the time of primary surgery was 6.6 ± 3.7 years old (2.0–13.2 years old), with a mean follow‐up of 64.2 ± 47.9 months (12–156 months). …”
Get full text

Itinerarios híbridos para lectores modernos. Un enfoque transmediático para textos de fantasía épica / Hybrid itineraries for modern readers. A transmedia approach to epic fantasy... by Isabel Jerez Martínez, Eduardo Encabo Fernández

“…Abstract The content of the following contribution focuses on epic fantasy literature and the formation of the reader in times of evanescent content. The main goal is to analyse the horizon of expectations of the reader in accordance with an era of transmedia manifestations, but which at the same time requires a social need for the hero. …”
Get full text

Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types by Gou XJ, Li LF, He XL, Chen X, Yu AY, Tian WY

“…Significant changes were noted in platelet count (PLT), activated partial thromboplastin time (APTT), and C-reactive protein (CRP) following transfusion (P < 0.05). …”
Get full text

Analysis of Sparse Trajectory Features Based on Mobile Device Location for User Group Classification Using Gaussian Mixture Model by Yohei Kakimoto, Yuto Omae, Hirotaka Takahashi

“…Location data collected from mobile devices via global positioning system often lack semantic information and can form sparse trajectories in space and time. This study investigates whether user age groups can be accurately classified solely from such sparse spatial–temporal trajectories. …”
Get full text

Russian Higher School: Forced Distance Learning and Planned Switch to Distance Learning During Pandemic (Experience of Sociological Analysis) by I. A. Aleshkovski, A. T. Gasparishvili, O. V. Krukhmaleva, N. P. Narbut, N. E. Savina

“…The overall uncertainty in the organization of the social life and the enforced and, at times, very contentious steps taken at various levels of management have caused polarization of opinions as to the functioning of all social institutions. …”
Get full text

Prevalence of anhedonia in women with deep endometriosis by Aida Mallorquí, Alessandra Fortuna, Emma Segura, Gemma Cardona, Marta Espinosa, Lara Quintas-Marquès, Meritxell Gracia, Elena Angulo-Antúnez, Francisco Carmona, María-Angeles Martínez-Zamora

“…This cross-sectional study reports, for the first time, the prevalence of anhedonia in a sample comprised by 212 premenopausal women with suspected DE referred to a tertiary hospital. …”
Get full text

Nonradiative and Radiative Recombination in CdS Polycrystalline Structures by E. Gaubas, V. Borschak, I. Brytavskyi, T. Čeponis, D. Dobrovolskas, S. Juršėnas, J. Kusakovskij, V. Smyntyna, G. Tamulaitis, A. Tekorius

“…Properties of polycrystalline CdS layers, employed in formation of the CdS-Cu2S heterostructures, have been studied by combining contactless techniques of the time and spectrally resolved photoluminescence (TR-PL) spectroscopy and microwave-probed photoconductivity (MW-PC) transients. …”
Get full text

Spontaneous pneumothorax: intubated or non-intubated surgery? by V.V. Tkalich, Yu.V. Nedilia, V.I. Borysova, O.V. Galiiev, S.I. Savoliuk

“…The two groups had comparable demographic, perioperative investigations, fluid infusions during surgery, the volume of surgery intraoperatively, blood loss, time for chest drain removal, length of stay in the hospital and the rate of complications. …”
Get full text

Karakteristik komposit bio-foam pati-glukomanan pada variasi formulasi perbandingan foaming agent natrium bikarbonat dengan asam sitrat by I Wayan Arnata, Early Dea Kartika Fiano, I Gusti Ayu Lani Triani

“…SEM analysis shows that bio-foam, adding a NaHCO3/CA, produces a relatively rougher and more porous surface. At the same time, its thermal stability is lower than that of bio-foam without adding a foaming agent.…”
Get full text

Efficacy and Safety of Murivenna Anal Infiltration Compared to Diltiazem Topical Application in Chronic Anal Fissure: Protocol for a Prospective, Randomized, Open-Label Clinical Tr... by Pratap Shankar KM, Indu Puthan Purayil, Palengara Binitha, Amit Kumar Rai, Sophia Jameela, Azeem Ahmad, Chandra Sekhara Rao Bhogavalli, Narayanam Srikanth, Rabinarayan Acharya

“…Ayurveda offers potential for more sustainable relief with fewer adverse effects. Murivenna oil is a time-tested medicated oil effectively used by Ayurvedic physicians for various ulcers of traumatic and pathological origin. …”
Get full text

SS-YOLO: A Lightweight Deep Learning Model Focused on Side-Scan Sonar Target Detection by Na Yang, Guoyu Li, Shengli Wang, Zhengrong Wei, Hu Ren, Xiaobo Zhang, Yanliang Pei

“…Thus, meeting our need to deploy SSS target detection algorithms on unmanned surface vessel (USV) for real-time target detection. Firstly, we replace the original complex convolutional method in the C2f module with a combination of partial convolution (PConv) and pointwise convolution (PWConv), reducing redundant computations and memory access while maintaining high accuracy. …”
Get full text

Measuring the impact introducing NHS 111 online had on the NHS 111 telephone service and the wider NHS urgent care system: an observational study by Richard M Jacques, Rebecca M Simpson, Tony Stone, Janette Turner, Jon Nicholl

“…Objectives To explore what impact introducing the National Health Service (NHS) 111 online service had on the number of phone calls to the NHS 111 telephone service and the NHS urgent care system.Design Observational study using a dose–response interrupted time series model and random-effects meta- analysis to estimate the average effect.Setting and participants NHS 111 telephone and online contacts for 18 NHS 111 area codes in England. …”
Get full text

Understanding the Effects of Selected Backpack Loads Carried for Certain Durations on Peak Forces of Walking Gait in School-Going Boys by Rabiya Husain, Dessalegn Wase Mola, Dhananjoy Shaw

“…Five backpack load conditions were analysed, namely, B1 = backpack load of 0 % of body weight (no additional weight in the backpack); B2 = backpack load of 8% of body weight; B3 = backpack load of 12 % of body weight; B4 = backpack load of 16 % of body weight; and B5 = backpack load of 20 % of body weight, at five following recording time, T1 = recording at zero minute of walking; T2 = recording at fifth minute of walking; T3 = recording at tenth minute of walking; T4 = recording at fifteenth minute of walking; T5 = recording at twentieth minute of walking. …”
Get full text

RISK FACTORS OF LIFE QUALITY REDUCTION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS by Vitalii Dubas

“…A questionnaire was conducted using the Medical Outcomes Study Short Form 36 questionnaire (SF-36) of 36 patients with systemic lupus erythematosus aged 18 to 62 years, regardless of disease activity at the time of examination, and 24 practically healthy persons, comparable in age and gender ratio. …”
Get full text

When to stop social learning from a predecessor in an information-foraging task by Hidezo Suganuma, Aoi Naito, Kentaro Katahira, Tatsuya Kameda

“…Using a behavioural experiment, we investigated how social information available from a preceding demonstrator affects the timing of becoming independent and individual performance thereafter. …”
Get full text