Dyssynchronous heart failure models in canines: New insights into electrocardiographic, echocardiographic and histological features by Han Jin, Shengwen Yang, Hao Huang, Sijing Cheng, Pengkang He, Sixian Weng, Min Gu, Hongxia Niu, Wei Hua, Yiran Hu, Hui Li

“…The RAP+LBBB group exhibited a prolonged overall ventricular activation time, delayed left ventricular activation, and lesser impact on the right ventricle. …”
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A Randomized Study to Compare the Effects of Once-Weekly Dulaglutide Injection and Once-Daily Glimepiride on Glucose Fluctuation of Type 2 Diabetes Mellitus Patients: A 26-Week Fol... by Huiqin Li, Xiaohua Xu, Jie Wang, Xiaocen Kong, Maoyuan Chen, Ting Jing, Zhiying Zhang, Guoping Yin, Xiaomei Liu, Yun Hu, Lei Ye, Xiaofei Su, Jianhua Ma

“…Furthermore, no statistically significant difference was found between the two groups in MBG, SDBG, MAGE, and MODD (P>0.05). The percentage time (PT) (>10 mmol/L and 3.9-10 mmol/L) of the two groups was significantly changed after the treatment (P<0.05). …”
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Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation by Lianling Xu, Lianling Xu, Kaixuan Zeng, Kaixuan Zeng, Zuoyue Duan, Zuoyue Duan, Jing Liu, Yan Zeng, Miao Zhang, You Yang, Qulian Guo, Yanling Jin, Wenjun Liu, Ling Guo

“…Subsequently, based on the results of metabolomics analysis and network pharmacology, cynaroside, nepitrin, and yuanhuanin were identified as potential antileukemia agents present in sweet potato for the first time; while CASP3, KDR, EGFR, and SRC were recognized as pivotal targets of these three monomers against AML. …”
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Associations of dose to the urethra and long-term patient-reported outcomes after radiotherapy with EBRT and HDR brachytherapy boost for prostate cancer by Lars Haack, David Krug, Justus Domschikowski, Olaf Wittenstein, Severin Rodler, Philipp Nuhn, Christof van der Horst, Claudia Schmalz, Christian Schulz, Oliver Blanck, Frank-André Siebert, Alexander Fabian

“…Results: Among 277 screened patients, 113 patients were alive, eligible, consented, and provided PRO. The median time passed since radiotherapy was 4 years. Per univariable analysis, a higher near maximum point dose of the urethra (DU0.1cc) was associated with worse urinary incontinence (r = -0.32; CI = −0.48 − -0.13; p < 0.001) and worse overall urinary function (r = -0.21; CI = −0.38 − -0.03; p = 0.02) of the respective EPIC-26 domains. …”
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Isolation of a tumor neoantigen specific CD8+ TCR from a skin biopsy of a vaccination site by Maria Paula Roberti, Pornpimol Charoentong, Yanhong Lyu, Marten Meyer, Stefan B. Eichmüller, Patrick Schmidt, Frank Momburg, Miray Cetin, Felix Hartmann, Nektarios A. Valous, Albrecht Stenzinger, Laura Michel, Peter Lichter, Andreas Schneeweiss, Verena Thewes, Carlo Fremd, Inka Zörnig, Dirk Jäger

“…Our study shows, for the first time, that tumor mutation – specific T cells are generated at high frequencies in the vaccination site and can be isolated with standard methods for TCR screening. …”
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Behavior of tellurium during vacuum thermal decomposition of Ag–Cu–Te alloy by Jia Deng, Hongjun Ding, Huan Luo, Xianjun Lei, Baoqiang Xu, Bin Yang

“…The experimental results show the volatilization of tellurium reached 99.93% at 1523 K, 10 Pa, and 480 min holding time, and the content of tellurium in the residue was only 0.0045 wt%. …”
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Simplified Physical Stability Assessment of Chilean Mine Waste Storage Facilities Using GIS and AI: Application in the Antofagasta Region by Gabriel Hermosilla, Gabriel Villavicencio, Giovanni Cocca-Guardia, Vicente Aprigliano, Manuel Silva, Juan Carlos Quezada, Pierre Breul, Vinicius Minatogawa, Jaime Morales

“…This approach reduces analysis time and minimizes human error. Validated in the Antofagasta Region, Chile&#x2019;s primary mining area, we identified and evaluated 70 WRD and 54 LWD. …”
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Integrating BRCA testing into routine prostate cancer care: a multidisciplinary approach by SIUrO and other Italian Scientific Societies by Giulia Mammone, Simona Borghesi, Nicolò Borsellino, Anna Caliò, Roberta Ceccarelli, Alessia Cimadamore, Giario Natale Conti, Laura Cortesi, Rolando Maria D’Angelillo, Gaetano Facchini, Lorena Incorvaia, Alberto Lapini, Luigi Mearini, Giovanni Pappagallo, Paolo Prontera, Daniela Turchetti, Grazia Sirgiovanni, Sergio Bracarda, on behalf of the Italian Society of Uro-Oncology (SIUrO)

“…A preliminary meeting convened teams from different Italian regions to establish minimal requirements for a mini-counseling program (defined as a pre-test consultation carried out by clinicians responsible of patients’ management) and propose care pathway models. At the same time, a comprehensive survey was launched to highlight regional variations in BRCA testing and identify eventual obstacles to testing activities. …”
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EIF1AX mutation in thyroid tumors: a retrospective analysis of cytology, histopathology and co-mutation profiles by Noha Elsherbini, Dong Hyun Kim, Richard J. Payne, Thomas Hudson, Véronique-Isabelle Forest, Michael P. Hier, Alexandra E. Payne, Marc P. Pusztaszeri

“…While 55% of thyroid nodules were benign at the time of surgery, the possible malignant transformation of these nodules, had they not been resected, is unknown. …”
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Dva příběhy z kriminálního podsvětí – padělatelé peněz na hradě Žampachu a přepadání Židů v roce 1542 by František Šebek

“… On around June 20th 1542, near Chlumec nad Cidlinou (at that time the estate of Jan of Pernštejn) two suspects were arrested: Jan Krška and the tavern-keeper Pavel of Nový Hrádek (district of Náchod). …”
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Mechanical response characteristics and damage mechanism of water-containing mudstone under low strain rate dynamic loading by Guichen LI, Sen YANG, Yuantian SUN, Jinghua LI, Haoran HAO, Zeyu SHAO

“…The results show that: ① low strain rate dynamic loading still has a weakening effect on the strength of mudstone, the ability of mudstone to resist the disturbance of dynamic loading decreases with the increase of water content, dynamic loading rate, and strength, and the strength damage reaches the maximum of 28.47%, 59.76%, and 31.56%, respectively. ② The acoustic emission characteristic parameter law shows that during the loading process, the mudstone has gone through four fracture evolution stages: initial damage, damage intensification, damage quiescence (exacerbation), and damage development, and the Kaiser effect is more obvious at the lower level of each factor in the dynamic loading perturbation stage, and the Felicity effect is more significant at the higher level of each factor. ③ The loading strain and plastic strain of the mudstone under the initial dynamic load disturbance are the largest, and the time of the second significant damage of the mudstone is advanced at higher levels of each factor. …”
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Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

“…Blood samples for circulating tumor DNA (ctDNA) will be collected before RT, during each week of treatment, and at the time of disease progression. The primary endpoint is progression-free survival (PFS) based on RECIST 1.1 or patient death. 1. …”
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Facilitating free travel in the Schengen area—A position paper by the European Association for Biometrics by Christoph Busch, Farzin Deravi, Dinusha Frings, Els Kindt, Ralph Lessmann, Alexander Nouak, Jean Salomon, Mateus Achcar, Fernando Alonso‐Fernandez, Daniel Bachenheimer, David Bethell, Josef Bigun, Matthew Brawley, Guido Brockmann, Enrique Cabello, Patrizio Campisi, Aleksandrs Cepilovs, Miles Clee, Mickey Cohen, Christian Croll, Andrzej Czyżewski, Bernadette Dorizzi, Martin Drahansky, Pawel Drozdowski, Catherine Fankhauser, Julian Fierrez, Marta Gomez‐Barrero, Georg Hasse, Richard Guest, Ekaterina Komleva, Sebastien Marcel, Gian Luca Marcialis, Laurent Mercier, Emilio Mordini, Stefance Mouille, Pavlina Navratilova, Javier Ortega‐Garcia, Dijana Petrovska, Norman Poh, Istvan Racz, Ramachandra Raghavendra, Christian Rathgeb, Christophe Remillet, Uwe Seidel, Luuk Spreeuwers, Brage Strand, Sirra Toivonen, Andreas Uhl

“…European Association for Biometrics (EAB), a non‐profit organisation, solicited the views of its members on ways which biometric technologies and services may be used to help with re‐establishing open borders within the Schengen area while at the same time mitigating any adverse effects. From the responses received, this position paper was composed to identify ideas to re‐establish free travel between the member states in the Schengen area. …”
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Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer by Tilo Wuensch, Jonas Wizenty, Janina Quint, Wolfgang Spitz, Madeleen Bosma, Olaf Becker, Andreas Adler, Wilfried Veltzke-Schlieker, Martin Stockmann, Sascha Weiss, Matthias Biebl, Johann Pratschke, Felix Aigner

“…Gene expression was determined by quantitative real-time PCR. In addition, FNDC expression data from publicly available Gene Expression Omnibus (GEO) data sets (GDS4296, GDS4515, and GDS5232) were analyzed. …”
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Kombinasi Intent Classification dan Named Entity Recognition pada Data Berbahasa Indonesia dengan Metode Dual Intent and Entity Transformer by Zahra Asma Annisa, Rizal Setya Perdana, Putra Pandu Adikara

“…In some cases such as banking services, customer service is needed that can be accessed at any time with high accuracy and responsiveness. For this high-quality service requirement, companies can implement the concept of excellent service. …”
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Informasi Dini Terhadap Penyakit Kanker Payudara berbasis Telepon Pintar by Hesti Lina Wiraswati, Savira Ekawardhani, Sarasati Windria, Arina Al Khaq, Fauzia Nurfitri, Dini Wahyuni, Nadya Rachmawati, Rusdi Toriq Baasin, Annissa Retno Arimdayu, Annisa Retno Arimdayu

“…The availability of information about breast cancer and smartphone-based self-examination is a necessity at this time. Therefore, we need the correct socialization. …”
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Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery by Arda Halu, Sarvesh Chelvanambi, Julius L. Decano, Joan T. Matamalas, Mary Whelan, Takaharu Asano, Namitra Kalicharran, Sasha A. Singh, Joseph Loscalzo, Masanori Aikawa

“…We validate the drugs predicted in our proofs-of-concept using real-time polymerase chain reaction (qPCR) experiments. …”
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Evaluating the surgical and oncological outcomes of hepatic artery variations in minimally invasive pancreaticoduodenectomy: insights from 2023 data at a high-volume pancreatic cen... by Tianyu Li, Liangbo Dong, Dongming Zhang, Jiashu Han, Menghua Dai, Junchao Guo, Qiang Xu, Weibin Wang, Xianlin Han, Chen Lin

“…While HAV is associated with longer operation times, other perioperative and oncological outcomes remain comparable between HAV/CR-HAV (+) and (-) groups.…”
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Combining UAV Remote Sensing with Ensemble Learning to Monitor Leaf Nitrogen Content in Custard Apple (<i>Annona squamosa</i> L.) by Xiangtai Jiang, Lutao Gao, Xingang Xu, Wenbiao Wu, Guijun Yang, Yang Meng, Haikuan Feng, Yafeng Li, Hanyu Xue, Tianen Chen

“…For orchards to get targeted, well-informed nitrogen fertilizer, accurate, large-scale, real-time monitoring, and assessment of nitrogen nutrition is essential. …”
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Renin–angiotensin–aldosterone system activation in plasma as marker for prognosis in critically ill patients with COVID-19: a prospective exploratory study by Katharina Krenn, Felix Kraft, Luana Mandroiu, Verena Tretter, Roman Reindl-Schwaighofer, Theresa Clement, Oliver Domenig, Matthias G. Vossen, Gregor Riemann, Marko Poglitsch, Roman Ullrich

“…Ang I, PRA-S, Ang 1–7 and Ang 1–5 concentrations correlated with the SOFA score both at the time of inclusion and after seven days, and driving pressure after seven days. …”
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